CN102552600A - Traditional Chinese medicine for preventing and treating chicken infectious laryngotracheitis and production method thereof - Google Patents
Traditional Chinese medicine for preventing and treating chicken infectious laryngotracheitis and production method thereof Download PDFInfo
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- CN102552600A CN102552600A CN201210025529XA CN201210025529A CN102552600A CN 102552600 A CN102552600 A CN 102552600A CN 201210025529X A CN201210025529X A CN 201210025529XA CN 201210025529 A CN201210025529 A CN 201210025529A CN 102552600 A CN102552600 A CN 102552600A
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Abstract
The invention discloses a traditional Chinese medicine for preventing and treating chicken infectious laryngotracheitis and a production method of the traditional Chinese medicine. The traditional Chinese medicine is prepared from the following raw material drugs according to a weight ratio: 100-400 of honeysuckle, 100-400 of radix scutellariae, 100-400 of tuber pinellia processed with ginger, 100-400 of dried orange peel, 100-400 of tuckahoe and 60-200 of licorice, wherein the honeysuckle, radix scutellariae, tuber pinellia processed with ginger, dried orange peel, tuckahoe and licorice are processed and extracted according to the amount so as to prepare into oral liquid, granulates, fluid extract, extract, powder, ultramicro powder and any pharmaceutical preparations capable of being clinically applied. The traditional Chinese medicine is significant in curative effect, is taken by drinking water or mixing with other materials, and is very convenient for transportation, storage and use.
Description
Technical field
The invention belongs to the animal and veterinary field, relate to a kind of Chinese medicine that is mainly used in the control infectious laryngotracheitis of chicken and preparation method thereof.
Background technology
Infectious laryngotracheitis of chicken (ILT) is the chicken acute upper respiratory tract infectious disease that is caused by a kind of herpes simplex virus group.Primary disease be characterized as dyspnea, breathe, expectoration band blood secretions, throat and tracheal mucosa swelling, hemorrhage, and form rotten to the cornly, the sickness rate during the acute outburst of this disease can reach 100%, case fatality rate is generally about 20%.There is laryngotracheitis to exist in that majority state is verified at present, and remains a kind of serious disease of the particularly big chicken crowd of susceptible chicken crowd, often cause heavy blow to poultry husbandry.
Aspect the prevention of primary disease, the immune effect of inactivated vaccine is relatively poor, and there is the danger of the poison that looses again in weak malicious Seedling.For this reason, Drug therapy remains indispensable control measure.Yet at present the unique medicine that allows to be used to treat ILT of country only is " HOUYANJING SAN " that " two ones of Chinese veterinary drug allusion quotations " recorded.This powder dosage is big, processing technology thereof is coarse simple, with low content of technology, and a large amount of useless compositions even harmful components are taken simultaneously, cause curative effect not satisfactory.And HOUYANJING SAN needs the spice interpolation, and transportation, storage and use are all very inconvenient, and then more inconvenient for the spice interpolation of pellet, therefore large-scale intensive culture field is just more and more lower to the frequency of utilization of HOUYANJING SAN.HOUYANJING SAN is processed oral liquid, granule and extractum etc. because of containing two mineral substance medicines of Realgar and Matrii Sulfas Exsiccatus and do not suit further to extract.
Summary of the invention
The object of the invention is exactly to solve the problems referred to above that exist in the prior art, provides a kind of evident in efficacy, and drinking-water or spice add, and transports, preserves and use and all prevent and treat Chinese medicine of infectious laryngotracheitis of chicken and preparation method thereof very easily.
For realizing above-mentioned purpose; Technical solution of the present invention is: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken; It is processed by following crude drug; By weight calculating, Flos Lonicerae 100-400, Radix Scutellariae 100-400, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100-400, Pericarpium Citri Reticulatae 100-400, Poria 100-400, Radix Glycyrrhizae 60-200.
The manufacture method of the Chinese medicine of above-mentioned described control infectious laryngotracheitis of chicken is extracted described Flos Lonicerae, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Pericarpium Citri Reticulatae, Poria and Radix Glycyrrhizae and to be processed oral liquid or process granule or process fluid extract or process extractum or process powder or process superfine powder according to the processing of said amount.The usage and the consumption of this pharmaceutical preparation are: the corresponding preparations that the 2g raw medicinal herbs is processed is converted water 1L or spice 0.5kg, supply fowl logotype 4～6 days.With the oral liquid is example, can be made into the oral liquid that 1ml contains the 1g raw medicinal herbs, mixes drink, and every 2ml converts water 1L, supplies fowl to drink logotype 4～6 days.
From Chinese veterinarian's medicine theory, this Chinese medicine is with the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) drying dampness to eliminate phlegm, and stopping nausea and vomiting by lowering the adverse flow of QI is a principal agent; Because of having pathogenic heat more, productive cough due to phlegm-damp violates lung and pestilential pathogen, so with Flos Lonicerae, Radix Scutellariae reducing heat and dispersing lung-QI, the detoxifcation pathogenic fire purging; With the Pericarpium Citri Reticulatae activating QI to eliminate phlegm, the suitable then expectorant of gas falls again, and gasifying then, expectorant disappears; Again because of expectorant by humidogene, the spleen rehabilitation is transported then turbid damp and can be changed, and wetly goes then that expectorant disappears, so be assistant with the Poria invigorating spleen to remove dampness; Make with Radix Glycyrrhizae and middle spleen invigorating, coordinate all medicines.Six medicines share, play heat clearing and damp drying, preventing phlegm from forming and stopping coughing altogether, regulate the flow of vital energy and in effect, be used for infectious laryngotracheitis of chicken and the control of the warm cough that causes.
From the modern medicine and pharmacology theory, the Flos Lonicerae heat-clearing and toxic substances removing, the heat radiation dispelling wind cures mainly the epidemic febrile disease heating, anemopyretic cold, cough due to lung-heat, laryngopharynx swelling and pain, toxic-heat and blood stasis etc.; The Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication cures mainly the cough due to lung-heat, the greedy drink of hyperpyrexia, carbuncle sore tumefacting virus, damp-heat dysentery etc.Silver yellow two medicines are all the key medicine of heat-clearing and toxic substances removing, are widely used in the treatment of several diseases viral disease.Infectious laryngotracheitis of chicken is the commonly encountered diseases toxicity disease of veterinary clinic, belongs to the pestilence category, controls suitable heat-clearing and toxic substances removing, thus first-selected silver yellow two medicines, and inhibition and killing action that this two medicine share avian infectious laryngotracheitis virus significantly strengthen.Simultaneously, the Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) of compatibility drying dampness to eliminate phlegm, Pericarpium Citri Reticulatae, the Poria of invigorating spleen to remove dampness, and coordinating the actions of various ingredients in a prescription Radix Glycyrrhizae reach the effect of the ILT of the warm cough of treatment performance jointly.
The present invention is evident in efficacy, and drinking-water or spice add, and transportation, storage and use are all very convenient.
The clinical efficacy test report
1 experimental animal is handled and is divided into groups
60 age in days test chickens of 240 body condition basically identicals are divided into VI group, 40 every group at random.According to the trial test observed result, most chickens 36h morbidity after contamination among the chicken crowd.Therefore, the drug test group is thrown in the medicine of corresponding dosage respectively in drinking-water or feedstuff behind collunarium contamination 36h, and 2 times/d, logotype 5d.Test chicken is freely drunk water and is searched for food.Observe the clinical symptoms of chicken before and after the medication, write down the death toll of chicken after the administration every day, (behind the counteracting toxic substances within the 36h) dead person disregards before the medication, adds up mortality rate and medicine effective percentage and the cure rate to chickling at last.The normal healthy controls group is virus inoculation not, does not also handle to medicine.See table 1 for details.
Table 1 test is divided into groups and medication
2 result of the tests
After the administration 7 days, statistics is respectively organized mortality rate, cure rate, effective percentage, sees table 2.
The different Chinese medicinal formulaes of table 2 are to the therapeutic outcome of artificial challenge ILT
Can find out that by table 2 the normal healthy controls group is not contaminated and raised separately, not have morbidity with dead; The middle and high dose groups mortality rate of the present invention is merely 5.0% and 7.5%, is starkly lower than the model control group that low dose group and HOUYANJING SAN group and contamination are not treated.From effective percentage, middle and high dose groups reaches 95.0% and 92.5% respectively, apparently higher than low dose group and HOUYANJING SAN group.From cure rate, middle and high dose groups reaches 92.5% and 90.0% respectively, is higher than low dose group and HOUYANJING SAN group equally.
Result of the test shows that the middle and high dose groups mortality rate of the present invention is minimum after the medication, and effective percentage and cure rate are the highest, and curative effect is best.So dosage is the clinical application amount in the recommendering folder invention.
3 conclusions
Chinese medicine drinking-water of the present invention administration, high, middle dose groups all can significantly improve the cure rate of the infectious laryngotracheitis of chicken of the warm cough of performance.So dose groups is clinical consumption in recommending, that is, and drinking-water, chicken, 2ml/L water (0.2%), every day 2 times, logotype 5 days.
The specific embodiment
Below in conjunction with specific embodiment the present invention is done further description.
Embodiment 1, a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 100, Radix Scutellariae 400, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 100, Poria 240, Radix Glycyrrhizae 60.
Embodiment 2: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 200, Radix Scutellariae 300, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 200, Pericarpium Citri Reticulatae 100, Poria 100, Radix Glycyrrhizae 100.
Embodiment 3: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 300, Radix Scutellariae 200, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 100, Poria 150, Radix Glycyrrhizae 150.
Embodiment 4: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 400, Radix Scutellariae 100, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 100, Poria 100, Radix Glycyrrhizae 200.
Embodiment 5: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 160, Radix Scutellariae 160, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 300, Pericarpium Citri Reticulatae 200, Poria 100, Radix Glycyrrhizae 80.
Embodiment 6: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 120, Radix Scutellariae 150, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 300, Poria 200, Radix Glycyrrhizae 130.
Embodiment 7: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 100, Radix Scutellariae 100, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 400, Poria 180, Radix Glycyrrhizae 120.
Embodiment 8: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 150, Radix Scutellariae 150, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 400, Pericarpium Citri Reticulatae 100, Poria 100, Radix Glycyrrhizae 100.
Embodiment 9: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 100, Radix Scutellariae 120, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 180, Pericarpium Citri Reticulatae 200, Poria 300, Radix Glycyrrhizae 100.
Embodiment 10: a kind of Chinese medicine of preventing and treating infectious laryngotracheitis of chicken, and it is processed by following crude drug, by weight calculating, Flos Lonicerae 200, Radix Scutellariae 100, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100, Pericarpium Citri Reticulatae 100, Poria 400, Radix Glycyrrhizae 100.
The Chinese medicine of above embodiment can be processed to extract and process oral liquid, also can be made into granule, fluid extract, extractum, powder, superfine powder and any pharmaceutical preparation that supplies clinical practice.
Claims (2)
1. Chinese medicine of preventing and treating infectious laryngotracheitis of chicken; It is characterized in that: it is processed by following crude drug; By weight calculating, Flos Lonicerae 100-400, Radix Scutellariae 100-400, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 100-400, Pericarpium Citri Reticulatae 100-400, Poria 100-400, Radix Glycyrrhizae 60-200.
2. the manufacture method of the Chinese medicine of the described control infectious laryngotracheitis of chicken of claim 1 is characterized in that: described Flos Lonicerae, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Pericarpium Citri Reticulatae, Poria and Radix Glycyrrhizae are extracted according to said amount processing process oral liquid or process granule or process fluid extract or process extractum or process powder or process superfine powder.
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Cited By (2)
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| CN103599288A (en) * | 2013-09-26 | 2014-02-26 | 挑战（天津）动物药业有限公司 | Traditional Chinese medicine oral liquid for treating chicken infectious laryngotracheitis and preparation method thereof |
| CN104206710A (en) * | 2014-08-15 | 2014-12-17 | 亚太兴牧(北京）科技有限公司 | Traditional Chinese medicinal feed additive containing N-carbamylglutamic acid, and its application |
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| CN101269168A (en) * | 2008-04-14 | 2008-09-24 | 王鲁云 | Traditional Chinese medicine for treating cough and asthma of children |
| CN101417065A (en) * | 2008-11-24 | 2009-04-29 | 律北平 | Oral traditional Chinese medicine formulation for treating chronic tracheitis |
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| CN101269168A (en) * | 2008-04-14 | 2008-09-24 | 王鲁云 | Traditional Chinese medicine for treating cough and asthma of children |
| CN101417065A (en) * | 2008-11-24 | 2009-04-29 | 律北平 | Oral traditional Chinese medicine formulation for treating chronic tracheitis |
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| CN103599288A (en) * | 2013-09-26 | 2014-02-26 | 挑战（天津）动物药业有限公司 | Traditional Chinese medicine oral liquid for treating chicken infectious laryngotracheitis and preparation method thereof |
| CN104206710A (en) * | 2014-08-15 | 2014-12-17 | 亚太兴牧(北京）科技有限公司 | Traditional Chinese medicinal feed additive containing N-carbamylglutamic acid, and its application |
| CN104206710B (en) * | 2014-08-15 | 2017-05-17 | 亚太兴牧(北京）科技有限公司 | Traditional Chinese medicinal feed additive containing N-carbamylglutamic acid, and its application |
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Denomination of invention: A traditional Chinese medicine for prevention and treatment of infectious laryngotracheitis and its preparation method Effective date of registration: 20210115 Granted publication date: 20131204 Pledgee: China Construction Bank Gaoyang sub branch Pledgor: BAODING JIZHONG PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980000409 |