CN102552537A - Chinese medicinal composition for treating qi and blood loss - Google Patents

Chinese medicinal composition for treating qi and blood loss Download PDF

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Publication number
CN102552537A
CN102552537A CN2011104261384A CN201110426138A CN102552537A CN 102552537 A CN102552537 A CN 102552537A CN 2011104261384 A CN2011104261384 A CN 2011104261384A CN 201110426138 A CN201110426138 A CN 201110426138A CN 102552537 A CN102552537 A CN 102552537A
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sheep embryo
chinese medicine
freeze
dried powder
medicine composition
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CN102552537B (en
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杨万政
刘悦
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DONGWUZHUMUQIN QI YUEYI BIO-TECH Co Ltd
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DONGWUZHUMUQIN QI YUEYI BIO-TECH Co Ltd
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Abstract

The invention discloses a Chinese medicinal composition for treating disorders qi and blood loss, which comprises the following medicinal raw materials in parts by weight: 50 to 200 of sheep embryo freeze-dried powder, 1 to 20 of Fructus Lycii, 1 to 20 of Citrus aurantium flower, 1 to 20 of hawthorn fruit and 1 to 20 of Radix Puerariae. The sheep embryo freeze-dried powder as major raw material is easily available and has a low cost. The other four materials which are both medicinal and edible are selected according to the theories in traditional Chinese medicine. The Chinese medicinal composition has a simple formula and a synergistic effect, is used for treating qi and blood loss of people of all ages, can achieve the effects of invigorating qi, nourishing blood, enhancing the health and prolonging lives, can improve both manifestations and root cause of diseases, has no toxic or adverse effect, and prevents relapsing after being used by patients.

Description

A kind of Chinese medicine composition that is used to treat deficiency of both QI and blood
Technical field
The present invention relates to a kind of Chinese medicine composition that is used to treat deficiency of both QI and blood, belong to the field of Chinese medicines.
Background technology
Deficiency of both QI and blood generally shows as and has a dizzy spell, deficiency of QI with disinclination to talk, weak spontaneous perspiration, pale white complexion or sallow, palpitation and insomnia, light red tongue and tender, thready and weak pulse etc., is diagnosed as anemia, subhealth state, senilism, puerperal blood deficiency, weak, menoxenia, amenorrhea etc. clinically.According to motherland's traditional medical theory, though the symptom of these diseases is different, the mechanism of studying carefully its morbidity all can be summed up as due to the deficiency of qi and blood, but subordination is in " asthenia ".Asthenia is to lose, day after tomorrow weak owing to natural endowment to support and function decline that multiple reasons such as diseases caused by exogenous pathogenic factor internal injury cause, with the passing of time the negative and positive of qi and blood loss is not main diseases again because of one type of disease.Theory of Chinese medical science thinks that the treatment deficiency of both QI and blood should focus on the recovery of coordinating YIN and YANG, benefiting vital QI and blood, promotion function.
At present, the Chinese medicine that is used to treat deficiency of both QI and blood mainly contains that hematonic compatibilities such as Qi-tonifying drugs such as Radix Ginseng, Radix Codonopsis, the Radix Astragali, Poria, Rhizoma Dioscoreae and Radix Angelicae Sinensis, Fructus Jujubae, Colla Corii Asini form, like the bolus of ten powerful tonics of extensive use clinically; Form by Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae (stir-fry), Poria, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Paeoniae Alba (wine stir-fry), Radix Rehmanniae Preparata, Radix Astragali Preparata and Cortex Cinnamomi, be used for QI and blood deficiency, pale complexion; The cardiopalmus of breathing hard, dizzy spontaneous perspiration, fatigue and asthenia; Extremity are not warm, menorrhagia, but this prescription contains Cortex Cinnamomi; Belong to warm drugs, the person avoids usefulness therefore to have the excess-heat, simultaneously clinical trial certificate affection of exogenous wind-cold, wind heat; Sheng person should not take in the excess-heat, also should not take simultaneously with a flu type medicine, and the use of this medicine is restricted.
Foetus Caprae seu Ovis has another name called Placenta caprae seu ovis; Its trophic component and human placenta's basically identical, trophic structure are near people's Placenta Hominis, and the special rich nutrient contents content of its rational natural structure becomes the first-selected kind of animal Placenta Hominis; Extensively be present in the NORTHWEST CHINA area; Mainly be used for extracting sheep placental extract in the market, be applied to cosmetic field, the application and development for preparing medicine as raw material of Chinese medicine also seldom.Chinese patent document CN101804165A discloses the preparation of a kind of clearing kidney toxicity, the strong vital organs of the human body, health invigorating slow down aging; Said preparation is except that containing Foetus Caprae seu Ovis powder; Also comprise 80 pleasant impression Chinese medicines such as Cordyceps militaris (L.) Link., Cornu Cervi Pantotrichum, Radix Codonopsis, Caulis Spatholobi, Radix Rehmanniae Preparata; This prescription prescription is complicated, contains valuable medicinals such as Cordyceps, Radix Ginseng, Radix Panacis Quinquefolii simultaneously, and cost is high.
Summary of the invention
Technical problem to be solved by this invention is that the Chinese medicine preparation that utilizes the sheep embryo to process in the prior art is complicated; The problem that cost is high; Provide a kind of prescription simple, the treatment cost is low, the Chinese medicine composition of treating deficiency of both QI and blood and preparation method thereof that is used to applied widely.
The invention provides a kind of Chinese medicine composition that is used to treat deficiency of both QI and blood, realize that through following technical scheme the weight portion of said composition crude drug is: freeze-dried powder of sheep embryo 50-200 part; Fructus Lycii 1-20 part; Citrus aurantium L. var. amara Engl. 1-20 part, Fructus Crataegi 1-20 part, Radix Puerariae 1-20 part.
The weight portion of preferred traditional Chinese medicinal composition raw materials of the present invention is: freeze-dried powder of sheep embryo 80-150 part, Fructus Lycii 2-10 part, Citrus aurantium L. var. amara Engl. 2-10 part, Fructus Crataegi 2-10 part, Radix Puerariae 1-20 part.
The weight portion of best traditional Chinese medicinal composition raw materials of the present invention is: 92 parts of freeze-dried powder of sheep embryo, 2 parts of Fructus Lycii, 2 parts of Citrus aurantium L. var. amara Engl.s, 2 parts of Fructus Crataegis, 2 parts of Radix Puerariaes.
Said freeze-dried powder of sheep embryo is for obtaining under-80~+ 50 ℃ of temperature said sheep embryo being carried out pulverizing after 20-30h is handled in lyophilizing.
Chinese medicine composition of the present invention can be made into pill, tablet, capsule, syrup, granule, powder, medicated wine.
The method for preparing of Chinese medicine composition of the present invention comprises the steps:
A) it is for use to take by weighing each crude drug of specified weight part;
B) Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become fine powder;
C) above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, get the active component of medicine of the present invention.
Wherein freeze-dried powder of sheep embryo is to obtain under-80~+ 50 ℃ of temperature said sheep embryo being carried out pulverizing after 20-30h is handled in lyophilizing.Said fine powder particle diameter is the 500-1200 order.
The invention still further relates to the purposes of this Chinese medicine composition in preparation treatment deficiency of both QI and blood medicine.
The principle of Chinese traditional treatment deficiency of both QI and blood and method mainly contain invigorating the spleen and regulating the stomach, QI invigorating and blood producing, the kidney invigorating hemopoietic, blood stasis dispelling hemopoietic, detoxifcation hemopoietic.
The sweet temperature of sheep embryo property is the in love article of the flesh and blood of enrich and benefit essence and blood, and is very wide in the application of area, Inner Mongol, classifies principal agent as; Fructus Lycii sweet in the mouth property is flat, goes into Liver and kidney two warps, nourishing the liver and kidney, replenishing vital essence to improve eyesight, and the kidney tonifying the yang aspect of yang of holding concurrently again with Radix Puerariae mutually 5, strengthens the power that strong waist is good for bone, is accessory drugs altogether.The experiment proof: give the mouse gavaging decoct every day, and hemopoietic function is had facilitation.
The acid of Citrus aurantium L. var. amara Engl. bitter in the mouth is slightly cold, and returns spleen lung large intestine channel, but alleviating distention in middle-JIAO regulate the flow of vital energy, help digestion and remove to expand; Be equipped with Fructus Crataegi circulation of qi promoting dissipating blood stasis, walk and do not keep, burnt unobstructed in the order, QI and blood is in harmonious proportion, and makes for assistant altogether.The experiment proof: ability facilitating digestion glandular secretion especially promotes the lipase secretion, to digest fat for good.
The above five tastes belong to the integration of edible and medicinal herbs article, and fit applications is played nourishing qi and blood, the strong bone of strong waist, benefit and oiliness and reach the effect of life lengthening altogether, to men and women, old and young's deficiency of both QI and blood, need QI replenishing and blood tonifying, disease-relieving and physique enhancing person all available it.For the costa sternales feeling of distension and oppression, dyspepsia does not disappear, and the stool impassable patient also can be effective.
The present invention has following advantage:
It is raw material that the present invention selects the sheep embryo for use, raw material be easy to get and cost low, simultaneously select Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi and Radix Puerariae for use according to Traditional Chinese medical theory; Belong to the integration of edible and medicinal herbs medical material together, prescription is simple, works in coordination with through each flavor medical material to play a role; Can be used for treating deficiency of both QI and blood, can play the effect of QI replenishing and blood tonifying, disease-relieving and physique enhancing, life lengthening, treating both the principal and secondary aspects of a disease; And have no side effect, use the back to be difficult for recurrence the patient.Chinese medicine composition of the present invention selects for use the Citrus aurantium L. var. amara Engl. alleviating distention in middle-JIAO to regulate the flow of vital energy, and helps digestion to remove to expand, and is equipped with Fructus Crataegi circulation of qi promoting dissipating blood stasis; The QI and blood regulating, effectively the facilitating digestion glandular secretion especially promotes the lipase secretion; Digestion fat; Thereby promote the absorption of body, under the prerequisite of not using big tonic such as Cordyceps, Radix Ginseng, play the effect of QI replenishing and blood tonifying, disease-relieving and physique enhancing, life lengthening nutritional labeling.Chinese medicine composition of the present invention further selects sheep embryo's lyophilized powder as crude drug; Thereby sheep embryo active component is remained fully through freeze drying technology; Avoided the sheep embryo is directly carried out the ruined problem of active component that drying causes; Thereby guaranteed the effective active composition of this Chinese medicine composition, improved its curative effect.
The specific embodiment
Embodiment 1
Take by weighing freeze-dried powder of sheep embryo 50g, Fructus Lycii 1g, Citrus aurantium L. var. amara Engl. 1g, Fructus Crataegi 1g, Radix Puerariae 1g is for use.
Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become 500 order fine powders;
Above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, incapsulate, make capsule of the present invention.
Embodiment 2
Take by weighing freeze-dried powder of sheep embryo 200g, Fructus Lycii 20g, Citrus aurantium L. var. amara Engl. 20g, Fructus Crataegi 20g, Radix Puerariae 20g is for use.
Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become 1200 order fine powders;
Above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, add Mel 150g, roll into a ball into the ball shape, make pill of the present invention.
Embodiment 3
Take by weighing freeze-dried powder of sheep embryo 92g, Fructus Lycii 2g, Citrus aurantium L. var. amara Engl. 2g, Fructus Crataegi 2g, Radix Puerariae 2g is for use.
Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become 850 order fine powders;
Above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, incapsulate, make capsule of the present invention.
Embodiment 4
Take by weighing freeze-dried powder of sheep embryo 80g, Fructus Lycii 2g, Citrus aurantium L. var. amara Engl. 2g, Fructus Crataegi 2g, Radix Puerariae 2g is for use.
Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become 1000 order fine powders;
Above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, adds ethanol and make binding agent, add starch and make filler, suppress granule of the present invention.
Embodiment 5
Take by weighing freeze-dried powder of sheep embryo 150g, Fructus Lycii 10g, Citrus aurantium L. var. amara Engl. 10g, Fructus Crataegi 10g, Radix Puerariae 10g is for use.
Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become 700 order fine powders;
Above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, add adjuvant and process granule, and dry, and compacting makes tablet of the present invention in flakes.
Freeze-dried powder of sheep embryo is the commercially available freeze-dried powder of sheep embryo by the sale of the happy skill of the pearl Mu Qin of Wu flag biotechnology Co., Ltd in the foregoing description.In addition, the freeze-dried powder of sheep embryo in the Chinese medicine composition according to the invention also can use any commercially available freeze-dried powder of sheep embryo.Freeze-dried powder of sheep embryo also can be chosen under-80~+ 50 ℃ of temperature the sheep embryo is carried out pulverizing the freeze-dried powder of sheep embryo that obtains after 20-30h is handled in lyophilizing.
Experimental example
In order to show this Chinese medicine composition to men and women, old and young's deficiency of both QI and blood, need QI replenishing and blood tonifying, disease-relieving and physique enhancing person's therapeutic effect, the present invention is through the clinical observation of 100 routine systems, and writes down its medical history, the state of an illness, age and original therapy method and compare efficacy experiment.
Suffer from anemia 30 people due to the deficiency of both QI and blood, subhealth state 15 people, puerperal asthenia 35 people, senilism 20 people among this 100 routine patient.In above-mentioned patient, great majority show as site of pathological change pain, swelling, stiff.Patient's course of disease of having is long reaches the more than ten years, and multiple therapy methods does not all have positive effect.
The criterion of clinical therapeutic efficacy is:
Clinical cure: original transference cure.
Produce effects: original symptom partly disappears.
Take a turn for the better: original state of an illness alleviates to some extent.
Invalid: the symptom and sign no change.
Medication is: give the patient capsule of oral embodiment 3 preparations.
The course of treatment: 15 days is a course of treatment, uses every day twice.
Clinical experiment is the result show, only uses this Chinese medicine composition of a course of treatment, and original symptom obviously alleviates.According to statistics, the light patient of 5% symptom can once cure, use a course of treatment after, reach 95% cure rate, 5% produce effects or improvement, no invalid situation (seeing table 1).
In above-mentioned clinical experiment, hematuria routine before and after patient's medication, hepatic and renal function, electrocardiogram etc. have been done inspection and record, contrast no abnormally, visible this Chinese medicine composition has no side effect, and after 2 years above-mentioned case is paid a return visit, and nothing recurs the patient.
Points for attention: 1, have in the body excess pathogen, stagnated fire person need not; 2, the person need not to have the interior-heat caused by deficiency of YIN; 3, avoid pungent.
Contrast experiment's example
Take by weighing 15g Cordyceps militaris (L.) Link., 15g Cornu Cervi Pantotrichum, 20g Radix Codonopsis, 15g Caulis Spatholobi, 20g Radix Rehmanniae Preparata, 25g Fructus Mori, 15g Gecko, the 15g Rhizoma Anemarrhenae, 15g Fructus Ligustri Lucidi, 15g Folium Ginkgo, 15g Semen Vitis viniferae extract, 15g Margarita powder, 15g propolis, 15g Radix Puerariae, 16g Fructus Hippophae, 15g Poria, 20g Arillus Longan, 15g Fructus Crataegi, 15g Fructus Rosae Laevigatae, 15g Semen Coicis, 15g Semen Persicae, 20g Pericarpium Citri Reticulatae, 15g Rhizoma Polygonati Odorati, 18g Folium Nelumbinis, 300g Ganoderma, 50g Aloe, 40g Radix Angelicae Sinensis, 23g Radix Ginseng, 40g Colla Corii Asini, 50g Foetus Caprae seu Ovis powder, 15g Cordyceps, 14g Ganoderma, the 23g Radix Astragali, 30g Fructus Lycii, 15g QUANGUI, 20g Trionyx sinensis (Wiegmann), 25g Radix Polygoni Multiflori, 14g Sucus Rosae Normalis, 15g Radix Glycyrrhizae, 13g dodder laurel, 15g Herba Cynomorii, 16g Rhizoma Polygonati, 15g Fructus Corni, 15g Herba Epimedii, 20g Radix Panacis Quinquefolii, 13g Colla cornus cervi, 20g Semen Cassiae, 16g Thelenota ananas (Jaeger) and 15g HUANGTAI, process preparation according to aforementioned Chinese patent document CN101804165A disclosed method.Use said preparation that 100 routine patients of identical body constitution, state of an illness state are carried out clinic trial, give said preparation a 10ml, 2 times on the one.
After taking 15 days continuously, the result is as shown in table 2, and its average cure rate can only reach 40%, and is prone to repeatedly after the drug withdrawal.
Though the present invention has carried out detailed elaboration through above-mentioned specific embodiment to it; But; Any form that does not exceed the claim protection domain that those skilled in the art should be understood that on this basis to be made and the variation of details all belong to invention which is intended to be protected.

Claims (9)

1. Chinese medicine composition, it is characterized in that: the weight portion of said composition crude drug is: freeze-dried powder of sheep embryo 50-200 part, Fructus Lycii 1-20 part, Citrus aurantium L. var. amara Engl. 1-20 part, Fructus Crataegi 1-20 part, Radix Puerariae 1-20 part.
2. Chinese medicine composition according to claim 1 is characterized in that: the weight portion of said crude drug is: freeze-dried powder of sheep embryo 80-150 part, Fructus Lycii 2-10 part, Citrus aurantium L. var. amara Engl. 2-10 part, Fructus Crataegi 2-10 part, Radix Puerariae 1-20 part.
3. Chinese medicine composition according to claim 2 is characterized in that: the weight portion of said crude drug is: 92 parts of freeze-dried powder of sheep embryo, 2 parts of Fructus Lycii, 2 parts of Citrus aurantium L. var. amara Engl.s, 2 parts of Fructus Crataegis, 2 parts of Radix Puerariaes.
4. according to the arbitrary described Chinese medicine composition of claim 1 to 3, it is characterized in that: said freeze-dried powder of sheep embryo is for obtaining under-80~+ 50 ℃ of temperature said sheep embryo being carried out pulverizing after 20-30h is handled in lyophilizing.
5. according to the arbitrary described Chinese medicine composition of claim 1 to 4, it is characterized in that: said Chinese medicine composition can be made into pill, tablet, capsule, syrup, granule, powder, medicated wine.
6. the method for preparing of the arbitrary described Chinese medicine composition of claim 1 to 4 comprises the steps:
A) it is for use to take by weighing each crude drug of specified weight part;
B) Fructus Lycii, Citrus aurantium L. var. amara Engl., Fructus Crataegi, Radix Puerariae pulverize separately are become fine powder;
C) above-mentioned fine powder is mixed with freeze-dried powder of sheep embryo, get the active component of medicine of the present invention.
7. method for preparing according to claim 6 is characterized in that: said freeze-dried powder of sheep embryo is for obtaining under-80~+ 50 ℃ of temperature said sheep embryo being carried out pulverizing after 20-30h is handled in lyophilizing.
8. method for preparing according to claim 6 is characterized in that: said fine powder particle diameter is the 500-1200 order.
9. the arbitrary said Chinese medicine composition of claim 1 to 4 is treated the purposes in the deficiency of both QI and blood medicine in preparation.
CN2011104261384A 2011-12-19 2011-12-19 Chinese medicinal composition for treating qi and blood loss Active CN102552537B (en)

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Cited By (3)

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CN105663319A (en) * 2016-03-16 2016-06-15 石药集团河北永丰药业有限公司 Traditional Chinese medicine composition for treating anemia and granular preparation and preparation method thereof
CN106467880A (en) * 2015-08-20 2017-03-01 伊犁肖尔布拉克酒业有限责任公司 A kind of preparation method of Placenta caprae seu oviss wine
CN114766619A (en) * 2022-05-30 2022-07-22 中山市美太保健制品有限公司 Health-care product oral liquid for delaying senility and preparation method thereof

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CN106467880A (en) * 2015-08-20 2017-03-01 伊犁肖尔布拉克酒业有限责任公司 A kind of preparation method of Placenta caprae seu oviss wine
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CN114766619A (en) * 2022-05-30 2022-07-22 中山市美太保健制品有限公司 Health-care product oral liquid for delaying senility and preparation method thereof

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