CN102516146B - 5位为氮的四元氮杂螺环衍生物及其制备方法和用途 - Google Patents
5位为氮的四元氮杂螺环衍生物及其制备方法和用途 Download PDFInfo
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- CN102516146B CN102516146B CN 201110378173 CN201110378173A CN102516146B CN 102516146 B CN102516146 B CN 102516146B CN 201110378173 CN201110378173 CN 201110378173 CN 201110378173 A CN201110378173 A CN 201110378173A CN 102516146 B CN102516146 B CN 102516146B
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- 0 C*C1(C)[U]N1* Chemical compound C*C1(C)[U]N1* 0.000 description 6
- DAHLUHBOWUHHOX-UHFFFAOYSA-N C1NCC11NCCC1 Chemical compound C1NCC11NCCC1 DAHLUHBOWUHHOX-UHFFFAOYSA-N 0.000 description 1
- WEFREESWPHICPL-UHFFFAOYSA-N CC(C)(C)OC(N(C1)CC1C#N)=O Chemical compound CC(C)(C)OC(N(C1)CC1C#N)=O WEFREESWPHICPL-UHFFFAOYSA-N 0.000 description 1
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CN 201110378173 CN102516146B (zh) | 2011-11-24 | 2011-11-24 | 5位为氮的四元氮杂螺环衍生物及其制备方法和用途 |
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CN 201110378173 CN102516146B (zh) | 2011-11-24 | 2011-11-24 | 5位为氮的四元氮杂螺环衍生物及其制备方法和用途 |
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CN102516146A CN102516146A (zh) | 2012-06-27 |
CN102516146B true CN102516146B (zh) | 2013-10-02 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2019152696A1 (en) * | 2018-01-31 | 2019-08-08 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
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JP4749715B2 (ja) * | 2002-07-05 | 2011-08-17 | ターガセプト,インコーポレイテッド | N−アリールジアザスピロ環式化合物、並びにその製造及び使用方法 |
CN101022801A (zh) * | 2004-08-20 | 2007-08-22 | 塔加西普特公司 | N-芳基二氮杂螺环化合物在成瘾治疗中的用途 |
CN101081851B (zh) * | 2006-05-30 | 2012-05-09 | 上海药明康德新药开发有限公司 | 一种α-氮杂螺环类药物模板的制备方法 |
US8735411B2 (en) * | 2006-10-02 | 2014-05-27 | Abbvie Inc. | Macrocyclic benzofused pyrimidine derivatives |
CN102711476B (zh) * | 2009-12-01 | 2014-12-03 | Abbvie公司 | 新的三环化合物 |
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WO2019152696A1 (en) * | 2018-01-31 | 2019-08-08 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
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Address after: Wenjiang District 610000 of Sichuan city of Chengdu province Chengdu Strait science and Technology Industry Development Park No. 488 West Ke Lin Lu Patentee after: Astatech (Chengdu) biological pharmaceutical Limited by Share Ltd Address before: Ke Lin Lu Xi Duan cross-strait science and Technology Industrial Development Park in Wenjiang District of Chengdu City, Sichuan Province, No. 488 611137 Patentee before: ASTATECH (CHENGDU) PHARM. CO., LTD. |
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Denomination of invention: Quaternary nitrogen varied volution derivate with 5 position as nitrogen and preparation method and use thereof Effective date of registration: 20170822 Granted publication date: 20131002 Pledgee: Chengdu SME financing Company Limited by Guarantee Pledgor: Astatech (Chengdu) biological pharmaceutical Limited by Share Ltd Registration number: 2017510000052 |
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Date of cancellation: 20180801 Granted publication date: 20131002 Pledgee: Chengdu SME financing Company Limited by Guarantee Pledgor: Astatech (Chengdu) biological pharmaceutical Limited by Share Ltd Registration number: 2017510000052 |
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