CN102512547A - Traditional Chinese medicine composition for treating canine distemper virus and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating canine distemper virus and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating canine distemper virus. The composition is prepared from pure natural herbs such as cordate houttuynia, honeysuckle, fructus forsythia, kawazure, radix sophorae flavescentis, cyrtomium fortune, Chinese violet, common andrographis herb, root of Chinese pulsatilla, radix isatidis and rhizoma alismatis. The invention further relates to a preparation method of the composition and use of the traditional Chinese medicine composition for preparation of the drug for treating the canine distemper virus. The product, disclosed by the invention, has remarkable treatment effect to early, middle and later stages of cases of the canine distemper virus.
Description
Technical field
The invention belongs to the veterinary medicine field, specifically, is a kind of Chinese medicine composition that is used to treat canine distemper virus, also relates to the application of said composition in the bad medicine of treatment canine distemper virus.
Background technology
In recent years, living standards of the people significantly improve, and population steps into aging society, and it is a kind of happy that the elderly keeps a pet, and house pet is a member in the family, no matter are that the people that city or rural area keep a pet gets more and more.Particularly after China's entry into the World Trade Organization; The house pet of introducing from countries in the world is various in style; Have from German shepherd, Australian Shepherd, English Springer Spaniel, Scotland shepherd dog, the U.S. can card, Borzoi, crust brother dog, Canis lupus familiaris, it is red to arrive Budgerigar greatly, little have 80 to the deer Canis familiaris L. surplus the famous and precious Canis familiaris L. of kind; Also have more than 20 kind of local various stupid Canis familiaris L.s, other has kind surplus the famous and precious cat 30.Streets and lanes and residential quarter in the city are found everywhere house pet miscellaneous, let the pedestrian see several unavoidably more.A lot of house pets are played together and are easy to the cross infection various diseases; Like diseases such as the extremely strong canine distemper disease of infectiousness, canine parvovirus disease, bacterial enteritis, dysentery, dysentery, viral transmissible gastroenteritis; Canine distemper disease particularly; Canine parvovirus disease is multiple, the deadly infectious disease of dog and other house pets, is difficult to cure, and mortality rate accounts for more than 98%.
Summary of the invention
An object of the present invention is to provide a kind of Chinese medicine composition of treating canine distemper virus, said composition is prepared from following Chinese medicine raw materials by weight proportion:
Preferably, said composition is prepared from following Chinese medicine raw materials by weight proportion:
Chinese medicine composition of the present invention can be processed various types of pharmaceutical preparatioies according to actual needs, for example processes injection, and is preferred but be not limited to injection.
Another object of the present invention provides a kind of treatment canine distemper virus preparation of compositions method, it is characterized in that: may further comprise the steps:
1, with Herba Houttuyniae, Flos Lonicerae, Fructus Forsythiae, Rhizoma Coptidis, Radix Sophorae Flavescentis; Rhizoma Osmundae, Herba Violae, Herba Andrographis, the Radix Pulsatillae, Radix Isatidis; The dried medicine raw material of Rhizoma Alismatis 11 flavor Chinese medicines cleans, cleans, drying, by weight weighing, adds multi-function extractor, adds the dried quality of medicinal material 8-12 of Chinese medicine purified water doubly, and is heated to and boils; Decocted 1-3 hour, medicinal liquid is leached, time filtrating of winning is subsequent use;
2, decocting for Chinese herbal medicine for the second time in multi-function extractor, adds the dried quality of medicinal material 6-10 of Chinese medicine purified water doubly, and is heated to and boils, and decocts 1-2 hour, medicinal liquid is leached, filtrate for the second time, subsequent use;
3, decocting for Chinese herbal medicine for the third time in multi-function extractor, adds the dried quality of medicinal material 4-6 of Chinese medicine purified water doubly, and is heated to and boils, and decocts 1-2 hour, medicinal liquid is leached, filtrate for the third time, subsequent use;
4, first time that step 1, step 2, step 3 is subsequent use, for the second time, filtrating places container to mix for the third time, deposition is filtered, and must filtrate, and is subsequent use;
5, step 4 gained filtrating is concentrated with the Chinese medicine vaporizer, concentrate concentration and be 2/5ths of filtrating, get concentrated solution, subsequent use;
6, step 5 gained concentrated solution is added the ethanol of 1 times of amount content 95%, carried out precipitate with ethanol 50-90 hour, then ethanol is separated, time fluid extract of winning; The ethanol of 0.8 times of amount of fluid extract adding first time content 95% was carried out precipitate with ethanol 30-80 hour, and separating alcohol gets fluid extract for the second time then; With the second time fluid extract add ethanol precipitate with ethanol 10-50 hour of 0.7 times of amount content 95%, and then separate ethanol, the crude drug extractum for preparing is subsequent use;
7, by the beastly officinal standard preparation of China, the crude drug extractum for preparing is adjusted to pH value 4.6～6.0, with the stock solution that configures, sterilization, packing promptly gets the injection of treating canine distemper virus.
Above-mentioned raw material and equipment are all commercially available to be arrived.
Need to prove that method of the present invention is a kind of preferable preparation technique but is not limited to this.Product by the inventive method preparation has good stability.
For many years, adopt Chinese medicine composition of the present invention, treatment canine distemper virus and be that routine effect is remarkable surplus the gastroenteropathy incomplete statistics 30,000 of characteristic with diarrhoea, enteritis, cure rate is more than 99%.
Chinese medicine composition of the present invention is to canine distemper virus, Canine Parvovirus, feline panleukopenia virus, hundstaupe exanthema virus, dog hemorrhagic intestinal class malignant bacteria, dog dust Li Shi body (rickettsia) pasteurellosis bacillus, and pathogen such as streptococcus all have very strong inhibition or killing action.Use the preparation of this Chinese medicine composition, can activate choline acetylase and the activity that suppresses choline enzyme, conditioning choline enzyme nervous system; Digestive system, the function of cardiovascular system, the enhance gastrointestinal road is to fat; Protein, the absorption of sugar and moisture content, and very strong astringing to arrest diarrhea effect is arranged.The combination of the prescription of this medicine is according to traditional Chinese medical science monarch, minister, the formulation principle scientific composition helping, make, each medicine form the back produce very strong collaborative or shape the antibacterial action of making a concerted effort, can improve tens of times of curative effects.
Pharmacological action: the present invention is a pure Chinese medicinal preparation, is efficient specially good effect, specially controls canine distemper, dog, and this medicine is to canine distemper, and Canine Parvovirus has strong inhibition or killing action.This product is to canine distemper, " canine parvovirus disease " early, in, evening, its case all had good therapeutic effect ".
Indication: sick dog spirit is depressed, and appetite is useless exhausted, and fervescence is vomitted more than 40 ℃, and ophthalmic has a large amount of viscosity; The purulence eye corner of the eyes, asoscope is dry, walks haltingly the atrophy of eyeball after 48 hours of falling ill on foot; Skin elasticity descends, and has loose bowels, and diarrhoea is serious, the serious dehydration phenomenon occurs.Nervous symptoms appears in the sick dog that has, and promptly warm thing is insane to expand, and diarrhoea appears in tic time quick property outbreak then, has blood in stool, and is brick-red, color of soy sauce, and cerise does not wait.This seasonal disease dog can not be stood, and in time injects the sinister pestilence spirit of dog injection, can in time alleviate the disease disease.The sinister pestilence spirit of dog injection is the specific drug of a kind of not controlling " Canine Parvovirus " severe disease, early, in, late period, sick dog was with this medicine cure rate a hundred per cent.Later stage, the poisoning of dehydration clothes appearred in sick dog, and condition of illness such as heart failure will be joined Energy mixture, vitamin C, and fluid infusion, heart tonifying, toxin expelling strengthens Comprehensive Treatments such as body immunity, and cure rate can reach 99 percent.
The functional component of treatment canine distemper virus Chinese medicine composition of the present invention is a Herba Houttuyniae, Flos Lonicerae, Fructus Forsythiae, Rhizoma Coptidis, Radix Sophorae Flavescentis, Rhizoma Osmundae, Herba Violae, Herba Andrographis, the Radix Pulsatillae, Radix Isatidis, Rhizoma Alismatis.
In the prescription of treatment canine distemper virus Chinese medicine composition of the present invention: put down in writing according to the Chinese medicine voluminous dictionary:
Herba Houttuyniae-[function cures mainly]: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, the dense infections of lung, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.
Flos Lonicerae-[function cures mainly]: heat clearing away, detoxifcation.Control the epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.
Herba Violae-[function cures mainly]: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Radix Isatidis-[function cures mainly]: heat clearing away, detoxifcation, removing heat from blood.Control influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, temperature is sent out speckle, and coma is told nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash.
Fructus Forsythiae-[function cures mainly]: heat clearing away, detoxifcation, eliminating stagnation, detumescence.Control warm, erysipelas, macule, the carbuncle toxic swelling, scrofula, urine stranguria with urinary obstruction.
Herba Andrographis-[function cures mainly]: heat-clearing and toxic substances removing, removing heat from blood detumescence.Control acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, the dense infections of lung, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.
Radix Sophorae Flavescentis-[function cures mainly]: heat clearing away, dampness, parasite killing.Control toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, furuncle leprosy malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula is scalded.
Rhizoma Osmundae-[function cures mainly]: kill ascarid, silk ribbon, pinworm, heat clearing away, detoxifcation, removing heat from blood, hemostasis.Control the branch hotness and emit, warm skin eruption is spitted blood epistaxis, discharging fresh blood stool, dysentery, metrorrhagia, leukorrhagia.
The Radix Pulsatillae-[function cures mainly] clearing away heat and cooling blood, detoxifcation.Control toxic-heat and blood stasis, pyrexial malaria cold and heat, epistaxis, internal hemorrhoid with bleeding.
Rhizoma Coptidis-[function cures mainly]: heat clearing and damp drying, eliminating fire and detoxication; Damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder, conjunctival congestion and swelling pain, fire-toxin carbuncle sore.The red skin of fish, the Bai Guanbai mouth is hemorrhage.
Rhizoma Alismatis-[function cures mainly]: diuretic, eliminating dampness by diuresis expels the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.
With the medical material in the above-mentioned prescription by weight ratio complex group be fitted together, have following effect:
1, pure Chinese medicinal preparation, pure green medicine, combination is novel, science, rationally, medicine is pollution-free, and noresidue has no side effect.Human body is had no effect.
2, curative effect is outstanding, and effect is remarkable, and dosage is few, and cost is low, the short treating period instant effect, and canine distemper, Canine Parvovirus cures 99%.
3, this prescription is new and effective antibiotic, antiviral drug, and it has antibiotic, and chemicals does not have the advantage of desirableization.
4, this prescription can be eliminated sinister element of the intravital intestinal of house pet and endotoxin, human body immunity improving function rapidly.
5, participate in reconciling the body biochemical reaction, reconcile nerve, cardiovascular, the function of digestive system.
6, protection heart, the enhance gastrointestinal absorbability, and very strong receipts wound anti-diarrhea effect is arranged, lasting medicine is stable.
For this reason, another object of the present invention provides the application of a kind of present composition in preparation treatment canine distemper disease cytotoxic drug.
The specific embodiment
Embodiment 1
Injection formulation (ProductName: dog poison pestilence spirit injection)
Raw material of Chinese medicine and consumption:
Herba Houttuyniae 2kg, Flos Lonicerae 1kg, Fructus Forsythiae 1kg, Rhizoma Coptidis 1kg, Radix Sophorae Flavescentis 1kg, Rhizoma Osmundae 1kg, Herba Violae 2kg, Herba Andrographis 2kg, Radix Pulsatillae 2kg, Radix Isatidis 2kg, Rhizoma Alismatis 1kg;
The method for preparing concrete steps are following:
1) with Herba Houttuyniae, Flos Lonicerae, Fructus Forsythiae, Rhizoma Coptidis, Radix Sophorae Flavescentis, Rhizoma Osmundae; Herba Violae, Herba Andrographis, the Radix Pulsatillae, Radix Isatidis, Rhizoma Alismatis ten simply the dried medicine raw material of Chinese medicine clean, clean, drying, be ground into coarse powder; By weight weighing: Herba Houttuyniae 2kg, Flos Lonicerae 1kg, Fructus Forsythiae 1kg, Rhizoma Coptidis 1kg, Radix Sophorae Flavescentis 1kg, Rhizoma Osmundae 1kg; Herba Violae 2kg, Herba Andrographis 2kg, Radix Pulsatillae 2kg, Radix Isatidis 2kg, Rhizoma Alismatis 1kg add in the extraction pot, inject purified water 160kg; The open vacuum automatic switch, and be heated to and boil, decocted 3 hours, medicinal liquid is leached, time filtrating of winning is subsequent use;
2) for the second time herb liquid extracts, and in multi-function extractor, injects 128 kilograms of purified water, and is heated to and boils, and decocts 2 hours, medicinal liquid is leached, filtrate for the second time, subsequent use;
3) herb liquid extracts for the third time, in multi-function extractor, injects 90 kilograms of purified water, and is heated to and boils, and decocts 1 hour, medicinal liquid is leached, filtrate for the third time, subsequent use;
4) first time that step 1, step 2, step 3 is subsequent use, for the second time, filtrating places container to mix for the third time, deposition is filtered, and must filtrate, and is subsequent use;
5) step 4 gained filtrating is concentrated with the Chinese medicine vaporizer, concentrate concentration and be 2/5ths of filtrating, get concentrated solution, subsequent use;
6) step 5 gained concentrated solution is added 1 times of ethanol of measuring content 95%, carried out precipitate with ethanol 72 hours, then ethanol is separated, time fluid extract of winning; The ethanol of 0.8 times of amount of fluid extract adding first time content 95% was carried out precipitate with ethanol 48 hours, and separating alcohol gets fluid extract for the second time then; With the second time fluid extract add the ethanol precipitate with ethanol 24 hours of 0.7 times of amount content 95%, and then separate ethanol, the crude drug extractum for preparing is subsequent use.
7) by the beastly officinal standard preparation of China; The crude drug extractum for preparing is adjusted to pH value 4.6～6.0,, in the workshop of ten thousand grades of GMP, pour in the 5ml cillin bottle by production procedure with the stock solution that configures; Sterilization again; Packing, 6 in every box is brown clear liquid and promptly gets the injection of treating canine distemper virus.
Usage and dosage: intramuscular injection or intravenous drip: per kilogram of body weight 0.1～0.4ml, use 5% glucose injection like the intravenous drip suggestion every day 1～2 time, 150～250ml mixed diluting slowly instils and penetrates (consumption is decided by the domestic animal size).
Embodiment 2
Injection formulation (ProductName: dog poison pestilence spirit injection)
Raw material of Chinese medicine and consumption:
Herba Houttuyniae 3kg, Flos Lonicerae 0.5kg, Fructus Forsythiae 0.5kg, Rhizoma Coptidis 0.5kg, Radix Sophorae Flavescentis 0.5kg, Rhizoma Osmundae 0.5kg, Herba Violae 1kg, Herba Andrographis 1kg, Radix Pulsatillae 1kg, Radix Isatidis 1kg, Rhizoma Alismatis 0.5kg;
Method for preparing is identical with the method for preparing of embodiment 1
Embodiment 3
Injection formulation (ProductName: dog poison pestilence spirit injection)
Raw material of Chinese medicine and consumption:
Herba Houttuyniae 1kg, Flos Lonicerae 1.5kg, Fructus Forsythiae 1.5kg, Rhizoma Coptidis 1.5kg, Radix Sophorae Flavescentis 1.5kg, Rhizoma Osmundae 1.5kg, Herba Violae 3kg, Herba Andrographis 3kg, Radix Pulsatillae 3kg, Radix Isatidis 3kg, Rhizoma Alismatis 1.5kg;
Method for preparing is identical with the method for preparing of embodiment 1
Embodiment 4
Clinical trial
Clinical symptoms:
Sick dog spirit is depressed, and appetite is useless exhausted, and fervescence more than 40 ℃, vomiting, ophthalmic have a large amount of viscosity, the purulence eye corner of the eyes, asoscope sick dog dry, that have nervous symptoms to occur: i.e. intermittent attacks such as spasm, epilepsy, tic.The appearance that continues diarrhoea, have blood in stool, brick-red, color of soy sauce, cerise do not wait, and occur serious dehydration phenomenon after three days, atrophy of eyeball, and skin elasticity descends, and has pinched the skin gauffer and has disappeared slow.Because acidosis appears in dehydration, heart failure and death.
4 groups of trouble " canine distemper disease, canine parvovirus disease " are carried out the treatment of clinical experiment property, suffer from dog for 325 every group, therapeutic outcome sees the following form:
1, uses " the injection formulation of embodiments of the invention 1 (ProductName: dog poison pestilence spirit injection) treatment " canine distemper disease ", " canine parvovirus disease " effect observation catalog (experimental group)
2, use " antibiotics, antiviral agents " treatment " canine distemper disease ", " canine parvovirus disease " effect observation catalog (matched group)
From the injection formulation of above-mentioned application embodiments of the invention 1 (ProductName: dog poison pestilence spirit injection) respectively two groups " canine distemper disease ", " canine parvovirus disease " are contrasted treatment with application " antibiotics, antiviral agents ".Result of the test shows that (ProductName: capacity treatment " canine distemper disease " dog poison pestilence spirit injection), " canine parvovirus disease " cure rate can reach 99% to the injection formulation of application embodiments of the invention 1.
Use " antibiotics, antiviral agents " and contrast treatment to two groups respectively.The result shows that cure rate is zero, can only be to have seldom a part of sick dog that slight improvement is arranged.Experiment proof antibiotics, antiviral agents are treated " canine distemper disease ", " canine parvovirus disease " is invalid.
More than instance of the present invention is specified, but said content is merely preferred embodiments of the present invention, can not be considered to be used to limit practical range of the present invention.All equalizations of doing according to application range of the present invention change and improve etc., all should belong within the patent covering scope of the present invention.
Claims (4)
1. Chinese medicine composition of treating canine distemper virus, said composition is prepared from following Chinese medicine raw materials by weight proportion:
2. a kind of Chinese medicine composition of treating canine distemper virus according to claim 1, it is characterized in that: said composition is prepared from following Chinese medicine raw materials by weight proportion:
3. according to the Chinese medicine composition of the described any one group of treatment canine distemper virus of claim 1-2, it is characterized in that: said compositions is an injection.
4. treat canine distemper virus preparation of compositions method for one kind, it is characterized in that: may further comprise the steps:
1) with Herba Houttuyniae, Flos Lonicerae, Fructus Forsythiae, Rhizoma Coptidis, Radix Sophorae Flavescentis; Rhizoma Osmundae, Herba Violae, Herba Andrographis, the Radix Pulsatillae, Radix Isatidis; The dried medicine raw material of Rhizoma Alismatis 11 flavor Chinese medicines cleans, cleans, drying, by weight weighing, adds multi-function extractor, adds the dried quality of medicinal material 8-12 of Chinese medicine purified water doubly, and is heated to and boils; Decocted 1-3 hour, medicinal liquid is leached, time filtrating of winning is subsequent use;
2) decocting for Chinese herbal medicine for the second time in multi-function extractor, adds the dried quality of medicinal material 6-10 of Chinese medicine purified water doubly, and is heated to and boils, and decocts 1-2 hour, medicinal liquid is leached, filtrate for the second time, subsequent use;
3) decocting for Chinese herbal medicine for the third time in multi-function extractor, adds the dried quality of medicinal material 4-6 of Chinese medicine purified water doubly, and is heated to and boils, and decocts 1-2 hour, medicinal liquid is leached, filtrate for the third time, subsequent use;
4) first time that step 1, step 2, step 3 is subsequent use, for the second time, filtrating places container to mix for the third time, deposition is filtered, and must filtrate, and is subsequent use;
5) step 4 gained filtrating is concentrated with the Chinese medicine vaporizer, concentrate concentration and be 2/5ths of filtrating, get concentrated solution, subsequent use;
6) step 5 gained concentrated solution is added 1 times of ethanol of measuring content 95%, carried out precipitate with ethanol 50-90 hour, then ethanol is separated, time fluid extract of winning; The ethanol of 0.8 times of amount of fluid extract adding first time content 95% was carried out precipitate with ethanol 30-80 hour, and separating alcohol gets fluid extract for the second time then; With the second time fluid extract add ethanol precipitate with ethanol 10-50 hour of 0.7 times of amount content 95%, and then separate ethanol, the crude drug extractum for preparing is subsequent use;
7) by the beastly officinal standard preparation of China, the crude drug extractum for preparing is adjusted to pH value 4.6～6.0, with the stock solution that configures, sterilization is packed again, promptly gets the injection of treating canine distemper virus.
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| CN103720929A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Andrographis paniculata injection |
| CN103720948A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Traditional Chinese medicine composition for treating canine distemper and canine parvovirus diseases |
| CN103720927A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Traditional Chinese medicine preparation for treating dairy cow mastitis |
| CN105434941A (en) * | 2015-12-22 | 2016-03-30 | 王琪 | Traditional Chinese medicine composition treating skin type canine distemper |
| CN107456516A (en) * | 2017-06-28 | 2017-12-12 | 禹州市合同泰药业有限公司 | A kind of traditional Chinese herbal decoction of effectively treatment dog pest |
| CN112293576A (en) * | 2020-10-30 | 2021-02-02 | 四川九章生物科技有限公司 | Application of chlorogenic acid in preparation of medicine or feed additive for preventing and/or treating canine parvovirus disease and canine distemper |
| JP2021512880A (en) * | 2018-01-31 | 2021-05-20 | スーチュワン インル ウェイトー ファーマスーティカル テクノロジー カンパニー リミテッド | Use of Bulbul extract in the manufacture of drugs to treat viral and / or bacterial diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720929A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Andrographis paniculata injection |
| CN103720948A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Traditional Chinese medicine composition for treating canine distemper and canine parvovirus diseases |
| CN103720927A (en) * | 2013-11-15 | 2014-04-16 | 北安市飞龙动物药厂 | Traditional Chinese medicine preparation for treating dairy cow mastitis |
| CN105434941A (en) * | 2015-12-22 | 2016-03-30 | 王琪 | Traditional Chinese medicine composition treating skin type canine distemper |
| CN107456516A (en) * | 2017-06-28 | 2017-12-12 | 禹州市合同泰药业有限公司 | A kind of traditional Chinese herbal decoction of effectively treatment dog pest |
| JP2021512880A (en) * | 2018-01-31 | 2021-05-20 | スーチュワン インル ウェイトー ファーマスーティカル テクノロジー カンパニー リミテッド | Use of Bulbul extract in the manufacture of drugs to treat viral and / or bacterial diseases |
| JP7021360B2 (en) | 2018-01-31 | 2022-02-16 | スーチュワン インル ウェイトー ファーマスーティカル テクノロジー カンパニー リミテッド | Use of light-vented bulbul extract in the manufacture of drugs to treat viral and / or bacterial diseases |
| CN112293576A (en) * | 2020-10-30 | 2021-02-02 | 四川九章生物科技有限公司 | Application of chlorogenic acid in preparation of medicine or feed additive for preventing and/or treating canine parvovirus disease and canine distemper |
| CN112293576B (en) * | 2020-10-30 | 2023-11-24 | 四川九章生物科技有限公司 | Application of chlorogenic acid in preparation of medicines or feed additives for preventing and/or treating canine parvovirus diseases and canine distemper |
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