CN102481440B - 包括纳米级突起的装置及其制造方法 - Google Patents

包括纳米级突起的装置及其制造方法 Download PDF

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Publication number
CN102481440B
CN102481440B CN201080028047.9A CN201080028047A CN102481440B CN 102481440 B CN102481440 B CN 102481440B CN 201080028047 A CN201080028047 A CN 201080028047A CN 102481440 B CN102481440 B CN 102481440B
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CN
China
Prior art keywords
projection
nanometer
nanoscale
cover
peripheral structure
Prior art date
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Expired - Fee Related
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CN201080028047.9A
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English (en)
Chinese (zh)
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CN102481440A (zh
Inventor
汉斯·洪欣赫尔
焦耳贾·帕斯托林
郑敏锐
李正国
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National University of Singapore
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National University of Singapore
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526—Methods of manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03—Automatic limiting or abutting means, e.g. for safety
    • A61B2090/032—Automatic limiting or abutting means, e.g. for safety pressure limiting, e.g. hydrostatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y10T29/49885—Assembling or joining with coating before or during assembling

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CN201080028047.9A 2009-04-23 2010-04-23 包括纳米级突起的装置及其制造方法 Expired - Fee Related CN102481440B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17191309P 2009-04-23 2009-04-23
US61/171,913 2009-04-23
PCT/SG2010/000164 WO2010123463A1 (en) 2009-04-23 2010-04-23 An apparatus that includes nano-sized projections and a method for manufacture thereof

Publications (2)

Publication Number Publication Date
CN102481440A CN102481440A (zh) 2012-05-30
CN102481440B true CN102481440B (zh) 2014-06-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080028047.9A Expired - Fee Related CN102481440B (zh) 2009-04-23 2010-04-23 包括纳米级突起的装置及其制造方法

Country Status (5)

Country Link
US (1) US20120089117A1 (de)
EP (1) EP2421595A1 (de)
CN (1) CN102481440B (de)
SG (2) SG175777A1 (de)
WO (1) WO2010123463A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8062568B2 (en) * 2009-08-27 2011-11-22 Korea University Research And Business Foundation Nano pattern writer
EP2563455A4 (de) * 2010-04-28 2014-02-19 Kimberly Clark Co Verfahren zur erhöhung der durchlässigkeit einer epithelialbarriere
RU2570280C2 (ru) 2010-04-28 2015-12-10 Кимберли-Кларк Ворлдвайд, Инк. Композитная матрица микроигл, содержащая на поверхности наноструктуры
DK2563450T3 (da) 2010-04-28 2017-11-13 Kimberly Clark Co Apparat til administration af rheumatoid-arthritis-medikament
US9522262B2 (en) 2010-04-28 2016-12-20 Kimberly-Clark Worldwide, Inc. Medical devices for delivery of siRNA
WO2011139640A2 (en) * 2010-05-06 2011-11-10 Applied Materials, Inc. Improved radiation heating efficiency by increasing absorption of a silicon containing material
EP3542851B1 (de) 2011-10-27 2021-12-15 Sorrento Therapeutics, Inc. Implantierbare vorrichtungen zur freisetzung bioaktiver wirkstoffe
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
JP6100271B2 (ja) 2011-10-27 2017-03-22 キンバリー クラーク ワールドワイド インコーポレイテッド 高粘性生理活性薬剤の経皮的送達
KR20130052825A (ko) * 2011-11-14 2013-05-23 삼성전자주식회사 반도체 발광소자
GB201304669D0 (en) * 2013-03-15 2013-05-01 Univ Singapore Micro-needles integrated with nanotubes
CN115154882A (zh) * 2014-03-26 2022-10-11 纳诺麦德皮肤护理公司 物质传送装置及头部
WO2016132996A1 (ja) * 2015-02-16 2016-08-25 凸版印刷株式会社 マイクロニードル
JP2016195651A (ja) * 2015-04-02 2016-11-24 日本写真印刷株式会社 マイクロニードルシート
KR20200043369A (ko) * 2017-06-16 2020-04-27 님 싸이언티픽 인코포레이티드 나노 니들 및 관련된 기기 및 방법
US11808713B2 (en) * 2020-07-30 2023-11-07 Epic Semiconductors Inc System for detecting pathogens in products
CN112370648A (zh) * 2020-10-30 2021-02-19 北京科技大学 一种塔形微针阵列皮肤贴及其制备方法和应用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101078026A (zh) * 2006-05-24 2007-11-28 江苏吴中高新技术实业有限公司 一种dna电化学传感器及其制备方法

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US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US20040063100A1 (en) * 2002-09-30 2004-04-01 Wang Chung Lin Nanoneedle chips and the production thereof
KR20060099523A (ko) * 2003-10-31 2006-09-19 알자 코포레이션 미세 돌출부 어레이를 위한 자가 작동 어플리케이터
US20060057388A1 (en) * 2004-09-10 2006-03-16 Sungho Jin Aligned and open-ended nanotube structure and method for making the same
WO2007061964A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Methods for coating microneedles
GB0622447D0 (en) * 2006-11-10 2006-12-20 Isis Innovation Ordered nanostructures and method of fabrication
FR2912919B1 (fr) * 2007-02-22 2009-05-01 Bernard Perriere Dispositif d'injection miniaturise a usage medical

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101078026A (zh) * 2006-05-24 2007-11-28 江苏吴中高新技术实业有限公司 一种dna电化学传感器及其制备方法

Also Published As

Publication number Publication date
EP2421595A1 (de) 2012-02-29
SG10201401744QA (en) 2014-08-28
CN102481440A (zh) 2012-05-30
SG175777A1 (en) 2011-12-29
US20120089117A1 (en) 2012-04-12
WO2010123463A1 (en) 2010-10-28

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent for invention or patent application
CB03 Change of inventor or designer information

Inventor after: JUNGINGER HANS

Inventor after: Pastorin Giorgia

Inventor after: Zheng Minrui

Inventor after: Li Zhengguo

Inventor before: Junginger Hans

Inventor before: Pastorin Giorgia

Inventor before: Zheng Minrui

Inventor before: Lee Chengkuo

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: HANS JUNGINGER PASTORIN GIORGIA ZHENG MINRUI LEE CHENGKUO VINCENT TO: JUNGINGER HANS PASTORIN GIORGIA ZHENG MINRUI LI ZHENGGUO

C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140625

Termination date: 20160423

CF01 Termination of patent right due to non-payment of annual fee