The specific embodiment
China's Chinese herbal medicine resource vast in territory divides abundant; Aspect the development Chinese herb feed additive great potential is being arranged; A large amount of production practices and scientific research have confirmed that also Chinese herbal medicine has many nutritional labelings and bioactivator, like alkaloid, polysaccharide, volatile oil, boots matter, organic acid etc., have the double action of the property of medicine and trophism concurrently; Both preventable disease can improve production performance again; Direct bactericidal not only, and can regulate the immunity function of body, have non-special antibacterial action.Therefore abandon the chemical classes additive, relieved feed addictive safe in utilization, making food reach the delicious effect of safety is our consistent pursuit; The more important thing is; The unique advantage of Chinese herb feed additive is to have pure natural property, from nature animal, plant and mineral matter, and has kept its natural structure and activity; The long-term use and drug residue free, the no resistance to the action of a drug and have no side effect; Be good green medicated premix, also catered to consumers in general and poultry farming person pursuit, in poultry production, seem more meaningful so make feed addictive with Chinese herbal medicine to the poultry prod of green non-pollution no drug residue; But; To its application on domestic fowl farming; Rest on the feeding experiment mostly; Lab analysis report is less, its hygiogenesis is inferred theoretically more, and domestic and international research mainly concentrates on the research of its production performance that improves poultry and feed conversion rate, raising immunity of organisms aspect at present.
Chinese herbal feed additive; Be meant that the traditional theory that the rerum natura of big right Chinese herbal medicine (yin, yang, tremble with fear, freeze, temperature, heat), thing flavor (sour, sweet, bitter, peppery, salty) and material is concerned with China is taken as the leading factor and with raising and feed ": subjects theory such as industry and technology are support, single and compound Chinese herb feed additive or the intermixture developed.The Research in China Chinese herbal medicine has long history, and before more than 2,000 year, " the fertile globefish method of numb salt " in " Huainan ten thousand is finished art " that the epoch Liu An of the Western Han Dynastry is write is to make an addition to the literature record the earliest in the feed about Chinese herbal medicine.Eastern Han Dynasty's epoch Chinese herbal medicine monograph Shennong's Herbal is loaded with: " the Chinese catalpa leaf is raised loose two times of pig " " paulownia is raised two times of the fertile people of pig " etc.The Jia Si Important Arts for the People's Welfare that warship is write in Northern and Southern Dynasties' epoch carry: " get three liters at wheat evil end and paddy and raise horse ', control Malaysia and China's paddy card.Ming Dynasty's Li Shizhen (1518-1593 A.D.) is loaded with a large amount of relevant knowledges on " herbal guiding principle day ", like " pipewort, can groom order fertile ", " yncaria stem with hooks is gone into several cun in wheat, cooks, and grooming, it is fertile to be prone to ", " root tuber of aromatic turmeric, horse is used it, invigorates blood circulation and mends " or the like.Since late 1970s; China expert, scholar begin to notice the bright prospects of Chinese herbal medicine as feed addictive; This has been carried out comparatively deep research and application, and to have occurred a collection of be the veterinary drug producer of soil with research and development Chinese herbal medicine and additive specially.A large amount of tests show that Chinese herbal feed additive can promote animal growth, improve production performance, improve the livestock products quality.Fear sounds (1993) etc. add little letter in layer diets fragrant, and the result finds that yolk color, chicken flavor all have clear improvement.More strengthen us and developed the resolution of Chinese medicine additive.Medium-height grass the effective elements of the medicine soil will have alkaloid, becomes class, volatile oil, naked class, resinae, organic acid, carbohydrate, egg is from matter, many skins and amino acid, and grease, wax, phytochrome etc.Active principle is absorbed the back by the animal body and participates in the microcirculation in the animal body, improves the chemical environment and the physical environment of cell, the potential of excitating organism self, thereby the normalization of realization histocyte organ dysfunction.Alkaloids (pickles alkali etc.), two types (genseng soap two etc.) are strengthened the reticuloendothelial system phagocytic function, and can generate by enhancing antibody, promote antigen-antibody reaction and lymphocyte transformation; Polysaccharide polysaccharide, yellow luxuriant polysaccharide, Radix Angelicae Sinensis polysaccharide, silver-colored imperial polysaccharide etc. such as () Huangs is immunocompetent main matter, has the reaction of the thymus gland of promotion, and what stimulate macrophage gulps down the sunlight function; Organic acid (forulic acid of aristolochic acid, cinnamic acid and sodium salt thereof, Radix Angelicae Sinensis, the water-soluble acid composition of Radix Codonopsis etc.) is regulated the pH value in the stomach and intestine; Prevent the breeding of harmful bacteria and the activity of raising enzyme; Promote eubolism in the animal body; Thereby improve the utilization rate of nutriment, promote the performance of breeding performonce fo animals; Volatile oil (allicin etc.) can obviously improve lymphocyte transformation rate, T lymphocyte acidity and a one acetic acid Cai fat positive rate, makes central lymphoid organs and peripheral lymphoid organs propagation, strengthens cellular immune function.
Specific embodiment 1: extracting honeysuckle 200g, frutus cnidii 200g, corydalis tuber 200g, fennel seeds 200g, motherwort 200g, selfheal 200g, cordate houttuynia 200g, root of large-flowered skullcap 200g; Putting into 10 times of water gagings after folium isatidis 200g, Radix Codonopsis 200g, Radix Astragali 200g, Radix Angelicae Sinensis 200g, medical stone 200g, Eclipta prostrata 200g, seed of Chinese dodder 200g, Sculellaria barbata 200g and the capsule of weeping forsythia 200g chopping soaked 1 hour; Heating and refluxing extraction 2 times; Each 45 minutes, extract active ingredient, No. 2 extracts are merged leave standstill.
Specific embodiment 2: the dregs of a decoction that 1 water in the specific embodiment extracted are put into 10 times of amount ethanol, and heating and refluxing extraction 2 times each 30 minutes, leaves standstill No. 2 extracts merging.
Specific embodiment 3: above-mentioned two kinds of extracts are merged, and decompression recycling ethanol and to be concentrated into liquor strength be 0.6g crude drug/mL is behind the suction filtration, when the relative density of filtrating is about 20 ℃ 1.08; Be decompressed to 0.03-0.08MPa, temperature remains on 60-80 ℃, and being concentrated into relative density is 1.20, and the medicinal extract that temperature to 60 is ℃-70 ℃ is put into oven for drying with medicinal extract and processed powder.
Specific embodiment 4: the component medicinal powder that obtains is added the lard that cools off, put into granulator and granulate, granular size 0.15mm～0.35mm when moulding is granulated, the trunnion of suitable chicken can not block the throat of chicken.
Specific embodiment 5: the preparation method when feed addictive is pill comprises:
Extracting honeysuckle 200g, frutus cnidii 200g, corydalis tuber 200g, fennel seeds 200g, motherwort 200g, selfheal 200g, cordate houttuynia 200g, root of large-flowered skullcap 200g; Folium isatidis 200g, Radix Codonopsis 200g, Radix Astragali 200g, Radix Angelicae Sinensis 200g, medical stone 200g, Eclipta prostrata 200g, seed of Chinese dodder 200g, Sculellaria barbata 200g and capsule of weeping forsythia 200g soaked 30 minutes to 1 hour; Heated and boiled 30～40 minutes; Filter filtrate for later use; Filter residue adds water and heats for the second time, boils 30～40 minutes, filters filtrate for later use; Filter residue adds water again, and heated and boiled is 30～40 minutes for the third time, filters filtrate for later use; Aforementioned three subsequent use filtratings are mixed, and heating is concentrated into pasty state, cools off after putting into 70 ℃～80 ℃ oven dry of baking oven; Fine powder is processed in the cooling of oven dry back, gets component medicinal powder.Bake out temperature is difficult for too high, and too high meeting makes the active component forfeiture in the Chinese medicine, thereby the forfeiture Expected Results, mixes starch or dextrin and adds water and process the pill that diameter is 0.15mm～0.25mm.
Specific embodiment 6: honeysuckle 200g, frutus cnidii 200g, corydalis tuber 200g, fennel seeds 200g, motherwort 200g, selfheal 200g, cordate houttuynia 200g, root of large-flowered skullcap 200g, folium isatidis 200g, Radix Codonopsis 200g, Radix Astragali 200g, Radix Angelicae Sinensis 200g, medical stone 200g, Eclipta prostrata 200g, seed of Chinese dodder 200g, Sculellaria barbata 200g and capsule of weeping forsythia 200g;
Get said Chinese medicine component medicine chopping and join in the multi-function extractor, the adding ratio of weight and number is that 3000 parts water logging was steeped 30～40 minutes, decocts after 1 hour, and decoction liquor is subsequent use for the first time in taking-up; Dregs of a decoction adding ratio of weight and number is after 3000 parts decocting boils 1 hour, to take out decoction liquor for the second time, twice decoction liquor is merged filter; It is 1000 parts solution that filtrate decompression is concentrated into ratio of weight and number; Staticly settled 24～36 hours, and drew supernatant, being concentrated into relative density is 1.04-1.05; The 14000-16000rps high speed centrifugation, getting supernatant concentration to relative density is 1.10-1.14; Can the soup that obtain directly be mixed feed and throw in nursing, also can work as water and give edible.
Specific embodiment 7: Chinese medicine additive in use, 0-14 age in days chick can be mixed in well-done millet and the egg yolk every day, every day, addition was 3% of a forage volume; Just can make chicken adapt to taste from little, and Chinese medicine additive itself also can prevent and treat the hidden danger virus of a variety of poultry, the one-tenth of the chicken quantity of living is improved greatly, also can making in the future, the egg quality is improved.The chicken son of 14-28 age in days can add in feed, and every day, addition was 2% of a forage volume; So just increased the immunity of chicken; But add 1% of forage volume every day behind 28 ages in days in feed, can improve the laying rate of chicken greatly, also adapted to the requirement of green safety food, and the double action of the property of medicine and trophism is arranged, and improved performance of products and quality greatly.
Specific embodiment 8: egg feedstuff comprises wheat bran, salt, maize pulp, fish meal, oyster shell whiting, rice bran, bean dregs and feed Chinese medicine additive.
Wherein, wheat bran 5～10 weight portions, salt 1～2 weight portion, maize pulp 5～10 weight portions, fish meal 5～10 weight portions, oyster shell whiting 5～10 weight portions, rice bran 50～70 weight portions, bean dregs 5～10 weight portions, feed Chinese medicine additive 1～15 weight portion.
Said feed Chinese medicine additive comprises following bulk drug: honeysuckle, frutus cnidii, corydalis tuber, fennel seeds, motherwort, selfheal, cordate houttuynia, the root of large-flowered skullcap, folium isatidis, Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, medical stone, Eclipta prostrata, the seed of Chinese dodder, Sculellaria barbata and the capsule of weeping forsythia.
The ratio of weight and number of said feed Chinese medicine additive bulk drug is: honeysuckle 10～15 weight portions, frutus cnidii 10～15 weight portions, corydalis tuber 10～15 weight portions, fennel seeds 10～15 weight portions, motherwort 10～15 weight portions, selfheal 10～15 weight portions, cordate houttuynia 10～15 weight portions, the root of large-flowered skullcap 10～15 weight portions, folium isatidis 10～15 weight portions, Radix Codonopsis 10～15 weight portions, the Radix Astragali 10～15 weight portions, Radix Angelicae Sinensis 10～15 weight portions, medical stone 10～15 weight portions, Eclipta prostrata 10～15 weight portions, the seed of Chinese dodder 10～15 weight portions, Sculellaria barbata 10～15 weight portions, the capsule of weeping forsythia 10～15 weight portions.
Said feed Chinese medicine additive accounts for 0.5%～15% of said egg feedstuff gross weight.
Said feed Chinese medicine additive, when formulation was granule, its preparation process was:
A. with said bulk drug chopping, soak extracting in water 2 times;
B. again with the dregs of a decoction alcohol extract that extracted among the step a 2 times;
C. above-mentioned two kinds of extracts are merged, reclaim ethanol and concentrate suction filtration, obtain component medicinal powder;
D. component medicinal powder is processed granule with animal fat.
Among the said step a, with the chopping of said component medicine, after putting into 10 times of water gagings and soaking, heating and refluxing extraction 2 times, each 30 minutes～1 hour, extract active ingredient, No. 2 extracts are merged leave standstill.
Among the said step b, the dregs of a decoction that water extracted are put into 10 times of amount ethanol, heating and refluxing extraction 2 times each 30 minutes～45 minutes, leaves standstill No. 2 extracts merging.
Among the said step c, above-mentioned two kinds of extracts are merged, decompression recycling ethanol and to be concentrated into liquor strength be 0.6g crude drug/mL is behind the suction filtration, when the relative density of filtrating is about 20 ℃ 1.08; Be decompressed to 0.03-0.08MPa, temperature remains on 60-80 ℃, and being concentrated into relative density is 1.20, and the medicinal extract that temperature to 60 is ℃-70 ℃ is put into oven for drying with medicinal extract and processed powder.
In the said steps d, the component medicinal powder that obtains is added animal fat, put into granulator and granulate, granular size 0.15mm～0.35mm when moulding is granulated.
Specific embodiment 9: the feed Chinese medicine additive that uses in the egg feedstuff; Comprise following bulk drug: honeysuckle 10～15 weight portions, frutus cnidii 10～15 weight portions, corydalis tuber 10～15 weight portions, fennel seeds 10～15 weight portions, motherwort 10～15 weight portions, selfheal 10～15 weight portions, cordate houttuynia 10～15 weight portions, the root of large-flowered skullcap 10～15 weight portions, folium isatidis 10～15 weight portions, the red sage root 10～15 weight portions, the Radix Astragali 10～15 weight portions, Radix Angelicae Sinensis 10～15 weight portions, medical stone 10～15 weight portions, Eclipta prostrata 10～15 weight portions, the seed of Chinese dodder 10～15 weight portions, Sculellaria barbata 10～15 weight portions, the capsule of weeping forsythia 10～15 weight portions;
The concrete method for making of said feed Chinese medicine additive is: get said Chinese medicine component medicine chopping and join in the multi-function extractor, the adding ratio of weight and number is that 3000 parts water logging was steeped 30～40 minutes, decocts after 1 hour, and decoction liquor is subsequent use for the first time in taking-up; Dregs of a decoction adding ratio of weight and number is after 3000 parts decocting boils 1 hour, to take out decoction liquor for the second time, twice decoction liquor is merged filter; It is 1000 parts solution that filtrate decompression is concentrated into ratio of weight and number, staticly settles 24～36 hours, draws supernatant; Being concentrated into relative density is 1.04-1.05, the 14000-16000rps high speed centrifugation, and getting supernatant concentration to relative density is 1.20; The medicinal extract that temperature to 60 is ℃-70 ℃ is put into oven for drying with medicinal extract and is processed powder.
Its method for using is:
When being used as the feed of 0-14 age in days chick, said egg feedstuff further comprises well-done millet and egg yolk; Said well-done millet accounts for 93.5% of feed gross weight, and said egg yolk accounts for 0.5% of feed gross weight; Said feed addictive accounts for 3% of feed gross weight.
During as the young feed of the chicken of 14-28 age in days, said feed addictive accounts for 2% of feed gross weight;
During as the feed of chicken behind 28 ages in days, but in feed, add 1% of forage volume every day.
In the feed Chinese medicine additive of the present invention:
Radix Angelicae Sinensis: its flavor is sweet and weigh, so specially can enrich blood, its gas is light and hot, thus again can promoting circulation of blood, and bowl spares has, in going benefit is arranged, the gas medicine in the sincere blood, the also panacea in the blood.About mending of assistant to mend then, thus can support nutrition blood, the tonifying Qi production of sperm, five viscera settling, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack then, so the defaecation bitterly of dispelling, relieving rigidity of muscles and joints is controlled contraction, paralysis, card such as dry, puckery.Seek void and the exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can loose greatly, and table is not held back the person, and assistant can be shown again with rheum officinale and so on admittedly.Precisely because gas Xin Erdong, so desire its quiet person when keeping away it, the sliding benefaction of property is defecated and is not consolidated the person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.
The Radix Astragali is main with qi-restoratives, ability invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, expelling pus and promoting granulation.Be used for that insufficiency of vital energy and blood, sore cave in, purulence becomes not burst or burst for a long time and do not hold back the person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration, i.e. the abscess suppuration myogenic of disunion for a long time.Modern medicine study shows that the Radix Astragali includes and multiple antibiotic effective ingredient, and the ability enhancing body's immunological function, therefore can also be used to prevent the generation of some infectious disease." book on Chinese herbal medicine meets former " carries: " Radix Astragali is can tonifying five zang organs all empty, controls arteries and veins string spontaneous perspiration, rushes down yin fire, removes lung heat, losslessly then sends out, and has sweat then to end." be the good medicine of promoting resistance and defence disease.
The little hardship of Sculellaria barbata, cold.Cure mainly heat-clearing, detoxifcation, the stasis of blood of loosing, hemostasis, haematemesis is controlled in analgesic therapy, nosebleed, blood drenches, dysentery characterized by blood in the stool, jaundice is had sore throat, lung carbuncle, furunculosis, scrofula, sore, cancerous swelling is fallen the wound of forging a knife, snake bite.Modern pharmacology research shows that Sculellaria barbata has effect clearing heat and detoxicating, promoting blood circulation and removing blood stasis, antitoxin snake bite.China often processes prescription to Sculellaria barbata and other Chinese herbal medicines, treatment hepatitis and various cancer such as cancer of the stomach, the carcinoma of the rectum, lung cancer, lymph cancer and gynecological tumor etc.
Cordate houttuynia is hot, is slightly cold.Return lung channel; Be used as medicine; The traditional Chinese medical science thinks that its flavor is hot, cold, can be clearing heat and detoxicating, the detumescence of row's pain treats sore, promoting urination and removing dampness, stomach strengthening and digestion promoting, and use and control real heat, heat poison, damp evil, disease heat and be the lung carbuncle of trouble, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc.; List is used or the compatibility compound, the equal determined curative effect of the use of oral administration and externally or multiple Dietotherapy method among the people.Pharmacological research, the cordate houttuynia master contains volatile oil, and multiple components such as decanoyl acetaldehyde decanoy acetaldehyde have the inhibition antibacterial action to various Xenorhabduses, coccus, influenza virus, Leptospira etc., and can improve the human immunity regulatory function.
The root of large-flowered skullcap has heat-clearing and damp-drying drug, and cool blood is antiabortive, detoxicating functions.Cure mainly diseases such as warm heat disease, the infection of the upper respiratory tract, cough with lung heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, the swollen furuncle sore of carbuncle.The clinical practice of the root of large-flowered skullcap is antibiotic not worse than the coptis, and does not develop immunity to drugs.We are by the strong characteristics of broad-spectrum antibacterial action, and it is special severe to be used in the fungal culture microbial contamination, fine with root of large-flowered skullcap extract effect." Bencao Jingshu ": the root of large-flowered skullcap, its property is respectful clearly, so remove evil: so bitter eliminating dampness; So cold sensation of the genitalia wins heat, so main all heat.All hot persons, heat symptoms caused by an exopathgen with all over heat also, jaundice, intestines be out-of-the-way, let out dysentery, the disease of all damp and hot victory is also analysed it, and is then all sick from recover.Bitter cold can be removed damp and hot, thus small intestine profit and water from pursuing, the source is clearly then flowed also clean.The blood person of closing, real heat is at blood system, and instant heating human blood chamber makes us obstructed through closing, damp and hot separating, then Ying Qi is clearly and voluntarily also.Dislike sore subcutaneous ulcer erosion person, blood-head is then stayed knot, and is that the swollen stain of carbuncle is mashed also: fiery ulcer person, the internal heat blood trouble also, cool blood heat extraction, then self-healing also.
The little hardship of selfheal, clearing liver, dissipating bind, diuresis; Control diseases such as seasonal febrile diseases, acute mastitis, order pain, jaundice, gonorrhoea, hypertension; Control that scrofula, thyroid gland enlargement, scrofula, goiter and tumor, acute mastitis, breast cancer, order pearl nyctalgia, photophobia are shed tears, under the vertigo, facial paralysis, arthralgia and myalgia, pulmonary tuberculosis, acute icteric catarrhal jaundice, metrorrhagia, band.Selfheal is the key medicine of clearing away the liver-fire, Disperse hepatic depression, and what it cured mainly is the illness of Liver Channel mostly.These article are equipped with chrysanthemum, cassia seed, can clear liver and improve vision, and control red eye, swell pain, be equipped with the shell of seaear, yncaria stem with hooks, but the pancake liver-yang is controlled headache, dizziness; Be equipped with article such as radix scrophulariae, the bulb of fritillary, oyster, but softening and resolving hard mass is controlled scrofula and is gone through tuberculosis." the southern regions of the Yunnan Province book on Chinese herbal medicine ": the liver wind of dispelling, the network of passing through is controlled facial paralysis.The row irritability is opened liver depression, ends arthralgia and myalgia, ophthal malgia, and the scrofula of loosing is stolen, whole body tuberculosis." the sward property of medicine be equipped with want ": remove the phlegm purulence that disappears, control scrofula, clear going up mended down, removes eye mask, pain relieving.Its drug effect is comparatively gentle, and taste neither be very bitter.
Radix Codonopsis property is flat, sweet, little acid of distinguishing the flavor of.Return spleen, lung channel.Tonifying middle-Jiao and Qi, invigorating the spleen benefit lung.Be used for a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst." book on Chinese herbal medicine justice " carries: Radix Codonopsis power ability tonifying spleen nourishing the stomach, and moistening lung is promoted the production of body fluid, gas in the tendon fortune, this is very mutually not far away with genseng.Its outstanding valuable person, invigorating the spleen fortune and not dry is then grown stomach-Yin and wet, and moistening lung and do not violate is cold and coolly nourished blood and is not grown greasyly partially, inspires clear sun, gas in the vibration, and do not have dry fraud just.Radix Astragali tonifying Qi, can rise enriching spleen-QI, can show admittedly by beneficial lung again.The Radix Codonopsis tonifying Qi can only the invigorating the spleen tonifying Qi, does not have the power of solid table, but Radix Codonopsis can also nourishing generate fluid, and the Radix Astragali does not then have the effect of promoting the production of body fluid, the Radix Astragali ability Li Shui that holds concurrently, and Radix Codonopsis does not have the Li Shui effect.This two flavors medicine share can tonifying middle-Jiao and Qi, improves resistance.
The capsule of weeping forsythia is bitter, is slightly cold.Return lung, the heart, small intestinl channel.Function is clearing heat and detoxicating, dispersing swelling and dissipating binds.Be used for ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease is from the beginning of, warm joining the army, high hot polydipsia, coma is sent out spot, and heat is drenched renal shutdown.The medicinal part of the capsule of weeping forsythia mainly is a fruit.Its shell, i.e. " sticking up " in " a kind of reed mentioned in ancient books sticks up detoxifying pills ".Contain forsythol, coumarin, oleanolic acid, saponin, citrin etc.Have effects such as heat-clearing, detoxifcation, dissipating bind apocenosis.Cure mainly warm, sore, scrofula, erysipelas, class's rash, influenza, be decocted in water for oral dose with fruit, or add in the prescription.Be usually used in anemopyretic cold.Nature,taste and action: Chinese medicine bitter, cold nature.Clearing heat and detoxicating, mass dissipating and swelling eliminating.The anaesthetic bitter, cool in nature." association's day " clearly, antidiarrheal.Cure mainly: Chinese medicine is controlled pyreticosis from the beginning of, anemopyretic cold, and heating is vexed, abscess of throat, and macula, erysipelas, scrofula, the carbuncle pyogenic infections from tumour or sore, acute nephritis, heat is drenched.The anaesthetic subcutaneous ulcer of harnessing the Yellow River, intestines shouting pain, " association day " disease, intestines heat.Sheng Nong's herbal classic ": main fever and chills, the mouse impotence, scrofula, carbuncle is swollen, dislikes sore, goiter and tumor, knot heat, disease due to noxious agents produced by various parasites.
Folium isatidis is mainly used in the heat poison and sends out diseases such as spot, erysipelas, abscess of throat, aphthae, sore and toxic.This medicine extensive use is clinically in recent years controlled above-mentioned all diseases except that available, can be used for the strongly fragrant lung of phlegm heat again, cough up phlegm yellow thick; Especially be usually used in popular second property encephalitis, but both single was applied to prevention, can cooperate radix bupleuri, honeysuckle flower, the capsule of weeping forsythia, Radix Isatidis, radix scrophulariae, the dried rhizome of rehmannia etc. again, can removing summer-heat the heat poison that divides of gas branch, battalion, availablely control various encephalitis, and comparatively suitable with the partial heat type." detailed outline ": " main pyrotoxic dysentery, jaundice, larynx numbness, erysipelas." " Lan Yezhi separates Chinese blister beetle, blue or green, the tree of heaven chicken of Yuan, cinnabar, arsenolite poison." " book on Chinese herbal medicine is just ": " controlled the hot poison of pestilence and goes mad, the wind-heat macula, and large carbuncle swells and ache, and relieving thirst and restlessness ends nosebleed epistaxis, haematemesis, kills infantile malnutrition due to digestive disturbances or intestinalparasites erosion, metal-inflicted wound curare.All with the heat malicious person that holds concurrently, all should blue leaf smash juice and use it.
Seed of Chinese dodder Gan Xinping goes into liver, kidney channel.Tonifying kidney and benefiting sperm nourishes the liver to improve visual acuity, and is antiabortive.Be used for caused by liver and kidney deficiency, soreness of waist and knee joint, impotence and seminal emission, frequent urination and enuresis, two blurred visions are dark, diseases such as fetal irritability.Function tonification liver kidney, the controlling nocturnal emission with astringent drugs urine that contracts, antiabortive, make eye bright antidiarrheal.Being used for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen suffers from a deficiency of the kidney and rushes down.
Medical stone is the traditional remedies of China, has the effect of soothing the liver, the removing toxicity for eliminating carbuncles of being good for the stomach, anti-ageing health care.Its main constituent has SiO2, Al2O3, Fe2O3 and CO2 etc.Medical stone has good stripping property and ion-exchange performance, and stripping property is better in sour environment.The pH value is 2.0 ~ 3.5 in the chicken stomach, and therefore, medical stone can provide required macroelement of chick and trace element, and good trophism is arranged.Medical stone also has certain biologically active, can promote the metabolism of organism and grows.Medical stone has loose structure, therefore suction-operated is arranged, and can adsorb noxious material, gas and moisture in the enteron aisle; Suppress the breeding of bacterium through the nitrogen in the absorption combination bacterioprotein; Harmful intestinal tract bacteria is reduced, the attenuation of intestines wall bacterial membrane, thus promote to digest and assimilate.It can also prolong feed in the gastral time of staying, promotes to digest and assimilate, and improves efficiency of feed utilization, reduces food consumption.
Frutus cnidii property is hot, bitter, temperature; Slightly poisonous.Return kidney channel.Cure mainly warming kidney to invigorate yang, eliminating dampness is dispeled the wind, desinsection.Be used for impotence, the palace is cold, under the cold-dampness band, and the arthritis with fixed pain caused by dampness pain in the back; Control eczema of vulva outward, married woman's pruritus vulvae; Trichomonas vaginitis is gynecological external use good medicine." Bencao Jingshu " carries: frutus cnidii, and bitter is flat; " not Lu " be hot sweet nontoxic; Modern detailed its smell, temperature is dry when holding concurrently, and sun is also.So swell and ache in housewife people's the moon, man's impotence is wet itches, and removes numbness gas, and sore is disliked in sharp joint." not Lu " warming the middle warmer and descending qi makes married woman's Zifu heat, and the man is cloudy strong, has made us son.Lid can dehumidify with tongue, and temperature can be loose cold, and suffering can be moistened kidney, and the beneficial spleen of sweet ability is so can remove the wet disease of viscera connecting with this channel of all cold of insufficiency type of married woman man.Cold-dampness was both removed, and then disease is gone, performance Yiyang, thus disease, and have help also.
Corydalis tuber is the stem of determining of Papaveraceae herbaceos perennial corydalis tuber.Its flavor is hot, bitter, warm in nature, the thoughts of returning home, liver, the spleen channel.Have invigorate blood circulation, the effect of promoting the circulation of qi, pain relieving.For invigorate blood circulation, the good medicine of sharp gas, pain relieving.The corydalis tuber beginning is carried " Kaibao Bencao ", says that " master breaks blood, and postpartum is at the cause of disease blood person of being for it; Married woman's irregular menstruation is lumpd in the abdomen, and metrorrhagia is drenched and revealed, and postpartum, blood was transported, and sudden and violent blood rushes to, because of decreasing down blood.Or wine rubs and boils clothes ".It " controls the Materia Medica of Decoction speech motive pain of lower abdomen, god is arranged ".Compendium of Material Medica speech its " the sharp gas of invigorating blood circulation, pain relieving, diuresis ", " stagnation of the circulation of vital energy in the ability promoting circulation of blood, stasis in the gas.So specially control all up and down all over the body pains ", " pained desire is dead, and speed is looked for and prolonged recklessly ".
The motherwort nature and flavor are arduous cool, have invigorate blood circulation, the effect of the method stasis of blood, menstruation regulating, the water that disappears.Control water, hematuria under irregular menstruation, the edema, rush down blood, dysentery, haemorrhoids.Motherwort contains various trace elements.The effect that selenium has the enhance immunity cell viability, relaxes the generation of atherosclerotic and improve human body defence function of diseases system; Manganese can be anti-oxidant, anti-aging, antifatigue and suppress the hyperplasia of cancer cell.So it is motherwort can beneficial face be improved looks, anti-ageing anti-old.
The honeysuckle heat-clearing poison that looses, Compendium of Material Medica carry " honeysuckle, being good at is malicious, so control ulcer, pyogenic infections, sore tinea ... ".Since ancient times, honeysuckle is usually used in clearing heat and detoxicating, the heating of treatment warm disease, toxic-heat and blood stasis, diseases such as large carbuncle.Modern pharmacological research shows, that honeysuckle has is antibacterial, antiviral, anti-inflammatory, analgesic, regulate the effect traditional Chinese medical science such as immunity and think that honeysuckle is cold in nature, flavor is sweet, gas is flat, have clearing heat and detoxicating effect, can treat diseases such as hot malicious early stage of pyogenic infection of skin, ulcer furunculosis.And have the diffusing effect of a surname concurrently.The honeysuckle antipyretic and antidote functions is quite strong.
Eclipta prostrata is traditional Chinese medical science liver-nourishing kidney-boosting, a cooling blood and hemostasis medicine commonly used.Multiple due to Light-headedness due to the deficiency of liver-yin and kidney-yin, tooth mobility, aching pain in waist and back, all diseases of flaccidity and weakness of the lower limbs and the blood-head gone out blood trouble good efficacy is arranged.Eclipta prostrata contains chemical compositions such as volatile oil, tannin, saponin, Eclipta prostrata element and vitamin A.Animal experiment has haemostatic effect, and in vitro test has inhibitory action to staphylococcus aureus.
The fennel seeds eliminating cold to stop pain, regulating qi-flowing for harmonizing stomach.Invigorate blood circulation, sharp gas, pain relieving are used for chest side of body institute abdomen pain, be used for cold hernia stomachache through closing dysmenorrhoea, stasis of blood resistance in postpartum, tumbling and swelling, the testis swelling and hanging down of either of the testes, dysmenorrhoea, few abdomen crymodynia, abdominal distention, food is few vomits and diarrhoea hydrocele testis.The salt fennel seeds are warmed up the kidney eliminating cold to stop pain.
Description of test
1. animal used as test
The blue brown laying hen in 56 seas in age in week
2.2 experimental design and daily ration are formed
2.2.1 experimental design
Test has design iterations for single-factor, and egg production is roughly close, health is anosis, the extra large blue brown laying hen of the big or small basically identical of body weight through observing in a week to select 400 56 ages in week, is divided into 4 groups at random; Every group 100, establish 5 repetitions in the group, each repeats 20; The 1st group of basal diet+0.5% Chinese medicine additive of the present invention of feeding; The 2nd group of basal diet+2% Chinese medicine additive of the present invention of feeding, the 3rd group of basal diet+4% Chinese medicine additive of the present invention of feeding, the 4th group is the control group fed basal diet.
2.2.2 daily ration is formed
Basal diet is for comprising wheat bran, salt, maize pulp, fish meal, oyster shell whiting, rice bran and bean dregs compound.
2.3 feeding and management
Test special feed company in the Jinan City carries out the breeding layer chicken field, and two layers of full staged are raised in cages, and are a recurring unit with 4 little cages of one deck, 3 one chickens of each little cage, and respectively the repeating of same processing taken all factors into consideration the locus factor and is uniformly distributed in the whole hen house.
The method that adopts artificial lighting and Bai Ran illumination to combine, every illumination 16h greatly, force ventilation+gravity-flow ventilation, free choice feeding, in vain by drinking-water.Every day 6:00,11:00,17:00 be feeding regularly, claims the star residual feed before the feeding, statistics feed consumption rate every day.9:00, temperature in the 14:0O record hen house, 10:oo, 17:30 regularly collect egg, write down every repetition egg number, the emblem of laying eggs, broken soft egg number and chicken number, calculate laying rate, the breakage rate of every day simultaneously.Monitoring chicken crowd health status, dead chicken number and the reason thereof of washing in a pan of record regularly carried out routine disinfection in the house.10 days preliminary trial periods, the test since July 20, Augusts 29 end of day, 40 days by a definite date.
2.4 sample collecting and processing
Gathered egg appearance respectively in the 10th, 20,30,40 days of test, each repeats to randomly draw 5 pieces, and label is with getting with inspection.Before the 20th, the 40 day blood sample collection of test, early morning feeding, each repeats to get at random 2, heart blood sampling sml injecting tube, and label, centrifugal back serum is sub-packed in the eppendorf pipe, and one 20 ℃ of refrigerators are preserved and are equipped with inspection.
2.5 detect index and method
2.5.1 production performance index
Record egg size, the number of laying eggs, inventory, residue material amount, livestock on hand chicken number calculate average egg weight, laying rate (comprising damaged egg), average daily ingestion amount, feedstuff-egg ratio (comprising damaged egg).Egg size (gram) is accurate to 0.01 gram with MPSOOB electronic balance weighing egg size.Laying rate (%)=(every day egg number/livestock on hand chicken number) x100 Chinese herbal feed additive is to the influence of laying hen production performance, egg product matter and blood parameters.
The feed consumption rate of feedstuff-egg ratio=weekly/lay eggs weekly heavily
3.1 Chinese herbal feed additive is to the influence of laying hen production performance
3.1.1 Chinese herbal medicine is to the influence of laying rate
The middle and later periods laying hen of laying eggs ages in this experiment selected 56 week, oneself downward trend occurs respectively to organize laying rate before on-test.As shown in table 1, l week, the 2nd group of (73%) laying rate was minimum, and the 3rd group (75.44%) is the highest, and each organizes difference not significantly (P>0.05); The 3rd group of laying rate of laying hen obviously raise and reached 79.52% the 2nd week; Improve 7 percentage points than control group 74.32%; Significant difference (P < 0.05), the 1st, 2 group is improved 2.31,6.22 percentage points of differences not significantly (P>0.05) than control group respectively, compares with l week; The test group laying rate all has improvement, and control group still has downward trend; The 3rd week the 2nd, 3 group of laying rate higher by 6.86% than control group respectively, 10.87%, significant difference (P < 0.05), the 1st group with each group difference not significantly (P>0.05); The 4th week beginning Chinese herbal medicine interpolation group laying rate all is significantly higher than control group (P < 0.05); In the 5th week, temperature significantly raises, and the control group laying rate descends rapidly, though each Chinese herbal medicine interpolation group laying rate also falls after rise to some extent, but still the utmost point is significantly higher than control group (P < 0.01); The 6th all Chinese herbal medicine interpolation group laying rate are asked liter to some extent, and control group continues to drop to 66.58%, and difference is (P < 0.01) extremely significantly; From the full phase; 1st, 2,3 groups of laying rate are respectively 75.53%, 76.87%, 77.72%; Higher 5.59,7.46,8.65 percentage points than control group 71.53; Difference is (P < 0.01) extremely significantly, and visible Chinese herb feed additive can significantly improve the laying rate that the laying hen age in days increases and summer high temperature causes and descend.
Table 1 Chinese herbal feed additive is to the influence of laying rate of laying hen
3.1.2 Chinese herbal medicine is to the influence of egg size, egg production, feed intake, feedstuff-egg ratio
The the 1st, 2,3 group of egg size as shown in table 2 all is higher than control group, but each group difference not significantly (P>0.05) explain that Chinese herb feed additive to the egg size influence not quite; 2nd, 3 groups of egg productions are respectively 4.79kg/d, 4.96 kg/d, and are higher by 4.13% than control group 4.60 kg/d, 7.82%, significant difference (P 0.os); Comparing with control group slightly for the 1st group increases, but difference not significantly (P>0.05) this shows that the 2nd, 3 group of Chinese herbal medicine interpolation group is better for improving the laying hen egg yield effect; Add after the Chinese herbal medicine in the daily ration; Each is tested Chinese herbal feed additive the feed intake that influences the group laying hen of laying hen production performance, egg product matter and blood parameters is all had a declining tendency; Be lower than control group 2.67g/d, 2.8 g/d respectively, 1.92 g/d, but difference not significantly (P>0.05); 1,2,3 groups feedstuff-egg ratio has descended 10.43%, 10.43%, 15.48% respectively, and difference extremely significantly (P < 0,01), I, 2, difference not significantly (P>0.05) between 3.This shows, add a certain proportion of Chinese herbal medicine in the feed and help improving efficiency of feed utilization, reduce feedstuff-egg ratio.
Table 2 Chinese herbal medicine to egg size, lay eggs, the influence of search for food dish, feedstuff-egg ratio
3. Economic and Efficiency Analysis
1st, 2,3 groups of egg productions all are higher than control group, and with identical sell at competitive, the egg income is higher than control group; Test group laying hen feed consumption rate all is lower than control group, and test group is added all a little higher than control group of Chinese herbal medicine cost, so the feed expenditure is higher; Relatively comprehensive, test group is respectively organized income apparently higher than control group, and is the highest with the 3rd group of income.In addition, if the test group egg is sold with high nutrition egg, the market price will be apparently higher than common Egg price so, and its total revenue also will be greatly improved.