CN107173604A - Improve the preparation method of the feed addictive of chicken immuological function - Google Patents

Improve the preparation method of the feed addictive of chicken immuological function Download PDF

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CN107173604A
CN107173604A CN201710246670.5A CN201710246670A CN107173604A CN 107173604 A CN107173604 A CN 107173604A CN 201710246670 A CN201710246670 A CN 201710246670A CN 107173604 A CN107173604 A CN 107173604A
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parts
filtrate
capsule
stir
radix scutellariae
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苫君强
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of preparation method for the feed addictive for improving chicken immuological function, including:Rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae part and the capsule of weeping forsythia;It will be mixed by mixed material with volumetric concentration for 50% ethanol solution, water bath sonicator, after ultrasonic 5 10min, the refluxing extraction at 90 DEG C, filtering, the first filter residue is mixed with volumetric concentration for 60% ethanol solution, water bath sonicator, the refluxing extraction at 90 DEG C, filtering mixes the second filter residue with volumetric concentration for 70% ethanol solution, water bath sonicator, the refluxing extraction at 90 DEG C, filtering mixes the first filtrate, the second filtrate and the 3rd filtrate;At 100 DEG C, ethanol is evaporated, the solid of water content≤10% is obtained.The feed addictive disclosed by the invention for improving chicken immuological function can not only effectively improve the survival rate of chicken, and can effectively improve the resistance against diseases of chicken.

Description

Improve the preparation method of the feed addictive of chicken immuological function
Technical field
The present invention relates to a kind of feed addictive, more particularly to a kind of preparation for the feed addictive for improving chicken immuological function Method.
Background technology
With China's expanding economy, birds animal husbandry has also obtained swift and violent development.Current birds raise predominantly big The concentration of scale formula is raised, and this yard feeding pattern is easy to monitor, managed and feeding, and cost-effective, but is due to not extensive Raise, which adds poultry disease infectious rate, once there are part birds to catch an illness, the infection of large area will soon be caused, Directly result in huge economic loss.
The content of the invention
It is an object of the invention to solve at least the above, and provide the advantage that at least will be described later.
It is a still further object of the present invention to provide a kind of feed addictive for improving chicken immuological function, it not only can be effective The survival rate of chicken is improved, and can effectively improve the resistance against diseases of chicken.
In order to realize that there is provided a kind of feed for improving chicken immuological function according to object of the present invention and further advantage The preparation method of additive, comprises the following steps:
It includes the raw material of following parts by weight:
10-20 parts of rhizoma Gastrodiae, 5-15 parts of yncaria stem with hooks, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, radix scutellariae 5- 15 parts and 10-15 parts of the capsule of weeping forsythia;
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, are rinsed after 10-30min, then rinse day with the clear water that temperature is 30 DEG C Fiber crops, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10-30min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 70-90 DEG C, drying to its water content is 5-10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 10-20 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:10 mixing, water bath sonicator, after ultrasonic 5-10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the first filtrate and the One filter residue, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasound After 5-10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the second filtrate and the second filter residue, by the second filter residue and and body The ethanol solution that product concentration is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, flowed back at 90 DEG C Extract after 1-3h, filtering obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filter Liquid;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
It is preferred that when, in the preparation method of the feed addictive of described raising chicken immuological function,
15 parts of 10 parts of rhizoma Gastrodiae, 5 parts of yncaria stem with hooks, 15 parts of cassia seed, 15 parts of stir-baked FRUCTUS GARDENIAE, 15 parts of lophatherum gracile, 15 parts of radix scutellariae and the capsule of weeping forsythia.
It is preferred that when, in the preparation method of the feed addictive of described raising chicken immuological function,
10 parts of 20 parts of rhizoma Gastrodiae, 15 parts of yncaria stem with hooks, 5 parts of cassia seed, 10 parts of stir-baked FRUCTUS GARDENIAE, 5 parts of lophatherum gracile, 5 parts of radix scutellariae and the capsule of weeping forsythia.
It is preferred that when, in the preparation method of the feed addictive of described raising chicken immuological function,
15 parts of rhizoma Gastrodiae, 10 parts of yncaria stem with hooks, 10 parts of cassia seed, 12 parts of stir-baked FRUCTUS GARDENIAE, 10 parts of lophatherum gracile, 10 parts of radix scutellariae and the capsule of weeping forsythia 12 Part.
It is preferred that when, in the preparation method of the feed addictive of described raising chicken immuological function,
In the step 5, the bath temperature is 50 DEG C.
The present invention at least includes following beneficial effect:
1. a kind of feed addictive for raising chicken immuological function that the present invention is provided, including 10-20 parts of rhizoma Gastrodiae, yncaria stem with hooks 5-15 10-15 parts of part, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, 5-15 parts of radix scutellariae and the capsule of weeping forsythia;Rhizoma Gastrodiae also known as red Arrow, solely shake sesame, from it is female, close from grass, refreshing grass, yellow moccasin flower, Mokpo, RHIZONA GASTRODIAE, DINGFENGCAO, Bai Longpi, be orchid family Gastrodia for many years Raw herbaceous plant, root-like stock is plump, no greenery, capsule obovate elliptic, and often with stem tuber or seminal propagation, its rhizome enters medicinal With treat have a dizzy spell, the disease such as extremity numbness, child convulsion, be rare Chinese medicine, treatment headache and insomnia, hook shared with the precious ganoderma lucidum of fine jade Rattan is used as medicine with the stem branch of buckle, and it has The flat liver of heat-clearing, and dispelling wind and relieving convulsion effect, modern pharmacology experiment also confirms that yncaria stem with hooks has decompression to make With, therefore with very high medical value;The root of radix scutellariae is used as medicine, bitter, cold in nature, there is heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, peace The effects such as tire.Cure mainly warm heat disease, the infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, movement of the foetus not The diseases such as peace, hypertension, carbuncle swells furuncle sore.The clinical antibiotic property of radix scutellariae is better than the coptis, and does not develop immunity to drugs, above-mentioned all medicines share The survival rate of chicken can not only be effectively improved, and can effectively improve the resistance against diseases of chicken.
2. a kind of method of the feed addictive for raising chicken immuological function that the present invention is provided, including by water and salt according to Mass ratio is 100:1 mixing, as in water bath sonicator, water bath sonicator obtains saline solution;Saline solution is heated to 50 DEG C, use 50 DEG C of saline solution rinses rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinses after 10-30min, then use Temperature rinses rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10-30min for 30 DEG C of clear water;By rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are as in drying unit, at 70-90 DEG C, drying to its water content For 5-10%;Use lapping device by rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia grind to form particle diameter for 10-20 μm of particle, the rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia that grind to form particle are ground as stirring Mix in device, be well mixed in the case where rotating speed is 100rpm, obtain mixed material;By the mixed material being mixed to get and volumetric concentration It is 1 in mass ratio for 50% ethanol solution:After 10 mixing, water bath sonicator, ultrasonic 5-10min, the refluxing extraction 1- at 90 DEG C After 3h, filtering obtains the first filtrate and the first filter residue, by the first filter residue with pressing quality with volumetric concentration for 60% ethanol solution Than for 1:After 10 mixing, water bath sonicator, ultrasonic 5-10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the second filtrate With the second filter residue, the ethanol solution for being 70% by the second filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, After ultrasonic 5-10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the 3rd filtrate, by first filtrate, the second filter Liquid and the mixing of the 3rd filtrate, obtain mixing filtrate;At 100 DEG C by mix filtrate in ethanol be evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function;Rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are ground to form into particle diameter 10-20 μm particle, it is conducive to extraction of the ethanol to active ingredient therein, and being extracted using the ethanol three of various concentrations can be effective The active principle in traditional Chinese medicine ingredients is extracted, prevents medicinal material from wasting.
Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.
Embodiment
The present invention is described in further detail below, to make those skilled in the art being capable of evidence with reference to specification word To implement.
It should be appreciated that such as " having ", "comprising" and " comprising " term used herein do not allot one or many The presence or addition of individual other elements or its combination.
Embodiment 1,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 10kg, yncaria stem with hooks 5kg, cassia seed 15kg, stir-baked FRUCTUS GARDENIAE 15kg, lophatherum gracile 15kg, radix scutellariae 15kg and capsule of weeping forsythia 15kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 10min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 70 DEG C, drying to its water content is 10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 20 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasound After 10min, at 90 DEG C after refluxing extraction 3h, filtering, obtain the second filtrate and the second filter residue, by the second filter residue with it is dense with volume The ethanol solution that degree is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, the refluxing extraction at 90 DEG C After 3h, filtering obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, and obtains mixing filtrate;Its In, bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Embodiment 2,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 20kg, yncaria stem with hooks 15kg, cassia seed 5kg, stir-baked FRUCTUS GARDENIAE 10kg, lophatherum gracile 5kg, radix scutellariae 5kg and capsule of weeping forsythia 10kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 30min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 30min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 90 DEG C, drying to its water content is 10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 20 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasonic 5- After 10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the second filtrate and the second filter residue, by the second filter residue and and volume The ethanol solution that concentration is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, flow back and carry at 90 DEG C Take after 3h, filter, obtain the 3rd filtrate, first filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate; Wherein, bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Embodiment 3,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 15kg, yncaria stem with hooks 10kg, cassia seed 10kg, stir-baked FRUCTUS GARDENIAE 12kg, lophatherum gracile 10kg, radix scutellariae 10kg and the capsule of weeping forsythia 12kg。
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 15min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 15min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 80 DEG C, drying to its water content is 5-10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 15 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasound After 10min, at 90 DEG C after refluxing extraction 3h, filtering, obtain the second filtrate and the second filter residue, by the second filter residue with it is dense with volume The ethanol solution that degree is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 10min, the refluxing extraction 3h at 90 DEG C Afterwards, filter, obtain the 3rd filtrate, first filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;Wherein, Bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Embodiment 4,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 11kg, yncaria stem with hooks 12kg, cassia seed 7kg, stir-baked FRUCTUS GARDENIAE 12kg, lophatherum gracile 7g, radix scutellariae 9kg and capsule of weeping forsythia 13kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 10min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 70-90 DEG C, drying to its water content is 10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 20 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasound After 10min, at 90 DEG C after refluxing extraction 3h, filtering, obtain the second filtrate and the second filter residue, by the second filter residue with it is dense with volume The ethanol solution that degree is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 10min, the refluxing extraction 3h at 90 DEG C Afterwards, filter, obtain the 3rd filtrate, first filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;Wherein, Bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Embodiment 5,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 19kg, yncaria stem with hooks 6kg, cassia seed 9kg, stir-baked FRUCTUS GARDENIAE 11kg, lophatherum gracile 14kg, radix scutellariae 13kg and capsule of weeping forsythia 12kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 30min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 70 DEG C, drying to its water content is 10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 10 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 5min, at 90 DEG C after refluxing extraction 1h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasonic 5min Afterwards, at 90 DEG C after refluxing extraction 1h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being with volumetric concentration 70% ethanol solution is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, at 90 DEG C after refluxing extraction 1h, Filtering, obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, and obtains mixing filtrate;Wherein, water Bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive agent.
Embodiment 6,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 19Kg, yncaria stem with hooks 14Kg, cassia seed 14Kg, stir-baked FRUCTUS GARDENIAE 14Kg, lophatherum gracile 14Kg, radix scutellariae 14Kg and the capsule of weeping forsythia 14Kg。
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 10min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 30min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 70-90 DEG C, drying to its water content is 5-10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 10-20 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasonic 5- After 10min, at 90 DEG C after refluxing extraction 3h, filtering, obtain the second filtrate and the second filter residue, by the second filter residue with it is dense with volume The ethanol solution that degree is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, the refluxing extraction at 90 DEG C After 3h, filtering obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, and obtains mixing filtrate;Its In, bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Embodiment 7,
A kind of feed addictive for improving chicken immuological function is present embodiments provided, including:
Rhizoma Gastrodiae 11Kg, yncaria stem with hooks 6Kg, cassia seed 6Kg, stir-baked FRUCTUS GARDENIAE 11Kg, lophatherum gracile 6Kg, radix scutellariae 6Kg and capsule of weeping forsythia 11Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving chicken immuological function and comprised the following steps:
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator is eaten Salt solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, hook are rinsed using 50 DEG C of saline solutions Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, rinse 30min after, then with temperature for 30 DEG C clear water flushing rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 30min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are extremely In drying unit, at 90 DEG C, drying to its water content is 10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, It is 10 μm of particle that radix scutellariae and the capsule of weeping forsythia, which grind to form particle diameter, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are in mass ratio 1:After 10 mixing, water bath sonicator, ultrasonic 5min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasonic 5min Afterwards, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the second filtrate and the second filter residue, by the second filter residue and and volumetric concentration It is 1 in mass ratio for 70% ethanol solution:After 10 mixing, water bath sonicator, ultrasonic 10min, at 90 DEG C after refluxing extraction 1h, Filtering, obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, and obtains mixing filtrate;Wherein, water Bath temperature is 50 DEG C;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising chicken immuological function feed addictive.
Comparative example and compliance test result example:
Feed formulation:By embodiment 1-5 prepare raising chicken immuological function feed addictive respectively with chicken feed according to Mass ratio is 1:77 are mixed to get addition feed, obtain the feeding feed that reference numeral is 1-5;
Subjects:The healthy disease-free chicken of 120 broken shells 3 days;
The foundation of test group and blank group:By 120 subjects, in the form of every group 20, it is divided into test group 1, examination Test group 2, test group 3, test group 4, test group 5 and blank group;
The feeding feed that the feeding of test group 1 numbering is 1, daily feeding 5 times, feeding 30 days;The feeding of test group 2 numbering is 2 Feeding feed, daily feeding 5 times, feeding 30 days;The feeding feed that the feeding of test group 3 numbering is 3, daily feeding 5 times, feeding 30 days;The feeding feed that the feeding of test group 4 numbering is 4, daily feeding 5 times, feeding 30 days;The feeding of test group 5 numbering be 5 feed Eat feed, daily feeding 5 times, feeding 30 days;Blank group feeding is not added with the feed of additive of the present invention, daily feeding 5 times, feeding 30 days.
The survival rate of chicken is detected after 30 days, one is the results are shown in Table.
Table one
Test group 1 Test group 2 Test group 3 Test group 4 Test group 5 Blank group
Survival rate 97% 97% 100% 99% 98% 91%
As can be seen from Table I, feed addictive of the feeding added with the embodiment 1-5 raising chicken immuological functions prepared Feeding feed chicken survival rate apparently higher than un-added.
Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art Other modification is realized, therefore under the universal limited without departing substantially from claim and equivalency range, the present invention is not limited In specific details.

Claims (5)

1. a kind of preparation method for the feed addictive for improving chicken immuological function, it is characterised in that comprise the following steps:
It includes the raw material of following parts by weight:
10-20 parts of rhizoma Gastrodiae, 5-15 parts of yncaria stem with hooks, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, 5-15 parts of radix scutellariae With 10-15 parts of the capsule of weeping forsythia;
Step 1, by water and salt according to mass ratio it is 100:1 mixing, as in water bath sonicator, water bath sonicator obtains saline solution;
Step 2, the saline solution that step 1 is prepared is heated to 50 DEG C, rhizoma Gastrodiae, yncaria stem with hooks, certainly are rinsed using 50 DEG C of saline solutions Pine torch, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia, are rinsed after 10-30min, then clear water flushing rhizoma Gastrodiae, hook with temperature for 30 DEG C Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and capsule of weeping forsythia 10-30min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae and the capsule of weeping forsythia are as baking In equipment for drying, at 70-90 DEG C, drying to its water content is 5-10%;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae It is 10-20 μm of particle to grind to form particle diameter with the capsule of weeping forsythia, will grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, Radix scutellariae and the capsule of weeping forsythia are ground as in agitating device, are well mixed in the case where rotating speed is 100rpm, are obtained mixed material;
Step 5, the ethanol solution for being 50% by the mixed material and volumetric concentration that are mixed to get by step 4 are 1 in mass ratio:10 After mixing, water bath sonicator, ultrasonic 5-10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the first filtrate and the first filter Slag, the ethanol solution for being 60% by the first filter residue and with volumetric concentration is 1 in mass ratio:10 mixing, water bath sonicator, ultrasonic 5- After 10min, at 90 DEG C after refluxing extraction 1-3h, filtering obtains the second filtrate and the second filter residue, by the second filter residue and and volume The ethanol solution that concentration is 70% is 1 in mass ratio:After 10 mixing, water bath sonicator, ultrasonic 5-10min, flow back and carry at 90 DEG C Take after 1-3h, filter, obtain the 3rd filtrate, first filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filter Liquid;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, and obtains water content≤10% Solid, is grinding to form the powder that particle diameter is 200 μm, then used in outside line light irradiation 10min, that is, obtain described raising by the solid The feed addictive of chicken immuological function.
2. the preparation method of the feed addictive of chicken immuological function is improved as claimed in claim 1, it is characterised in that
15 parts of 10 parts of rhizoma Gastrodiae, 5 parts of yncaria stem with hooks, 15 parts of cassia seed, 15 parts of stir-baked FRUCTUS GARDENIAE, 15 parts of lophatherum gracile, 15 parts of radix scutellariae and the capsule of weeping forsythia.
3. the preparation method of the feed addictive of chicken immuological function is improved as claimed in claim 1, it is characterised in that
10 parts of 20 parts of rhizoma Gastrodiae, 15 parts of yncaria stem with hooks, 5 parts of cassia seed, 10 parts of stir-baked FRUCTUS GARDENIAE, 5 parts of lophatherum gracile, 5 parts of radix scutellariae and the capsule of weeping forsythia.
4. the preparation method of the feed addictive of chicken immuological function is improved as claimed in claim 1, it is characterised in that
12 parts of 15 parts of rhizoma Gastrodiae, 10 parts of yncaria stem with hooks, 10 parts of cassia seed, 12 parts of stir-baked FRUCTUS GARDENIAE, 10 parts of lophatherum gracile, 10 parts of radix scutellariae and the capsule of weeping forsythia.
5. the preparation method of the feed addictive of chicken immuological function is improved as claimed in claim 1, it is characterised in that the step In rapid 5, the bath temperature is 50 DEG C.
CN201710246670.5A 2017-04-16 2017-04-16 Improve the preparation method of the feed addictive of chicken immuological function Pending CN107173604A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102450515A (en) * 2010-12-06 2012-05-16 山东六和集团有限公司 Laying hen feed and traditional Chinese medicine feed additive used by same
CN105533253A (en) * 2016-01-05 2016-05-04 闫冷 Feed additive for treating quail disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102450515A (en) * 2010-12-06 2012-05-16 山东六和集团有限公司 Laying hen feed and traditional Chinese medicine feed additive used by same
CN105533253A (en) * 2016-01-05 2016-05-04 闫冷 Feed additive for treating quail disease

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Application publication date: 20170919