CN102414312A - 从植物细胞培养物中生产和抽提原花青素 - Google Patents

从植物细胞培养物中生产和抽提原花青素 Download PDF

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Publication number
CN102414312A
CN102414312A CN2009801590925A CN200980159092A CN102414312A CN 102414312 A CN102414312 A CN 102414312A CN 2009801590925 A CN2009801590925 A CN 2009801590925A CN 200980159092 A CN200980159092 A CN 200980159092A CN 102414312 A CN102414312 A CN 102414312A
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cocoa
cell
pycnogenols
culture
theobroma
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Chinese (zh)
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M·文卡特拉莫斯
D·R·瓦格纳
S·拉尔
F·勒雅尔
S-Y·尹
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Dianaplantsciences Inc
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Dianaplantsciences Inc
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0025Culture media for plant cell or plant tissue culture
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/002Culture media for tissue culture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2009801590925A 2009-04-03 2009-05-04 从植物细胞培养物中生产和抽提原花青素 Pending CN102414312A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16659109P 2009-04-03 2009-04-03
US61/166,591 2009-04-03
PCT/US2009/042722 WO2010114567A1 (en) 2009-04-03 2009-05-04 Production and extraction of procyanidins from plant cell cultures

Publications (1)

Publication Number Publication Date
CN102414312A true CN102414312A (zh) 2012-04-11

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CN2009801590925A Pending CN102414312A (zh) 2009-04-03 2009-05-04 从植物细胞培养物中生产和抽提原花青素

Country Status (7)

Country Link
US (1) US8568798B2 (de)
EP (2) EP2414509B1 (de)
JP (2) JP5789595B2 (de)
KR (2) KR20160054015A (de)
CN (1) CN102414312A (de)
BR (1) BRPI0925040A2 (de)
WO (1) WO2010114567A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106109512A (zh) * 2016-06-27 2016-11-16 郭迎庆 一种可可多酚咀嚼片的制备方法
CN114126400A (zh) * 2019-06-07 2022-03-01 马斯公司 可可细胞悬浮方案

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103237457A (zh) * 2010-10-04 2013-08-07 戴安娜植物科学有限公司 从植物细胞培养物产生和提取原花青素
US20130323843A1 (en) * 2011-02-04 2013-12-05 Dianaplantsciences, S.A.S. Polyphenol production by vaccinium myrtillus cell cultures
WO2013170155A2 (en) 2012-05-11 2013-11-14 The Hershey Company Methods of purifying and identifying the presence of and levels of procyanidin oligomeric compounds
US20140087026A1 (en) * 2012-09-26 2014-03-27 Dianaplantsciences, S.A.S. Novel food composition of whole plant cells
CN104020227B (zh) * 2014-05-21 2015-08-19 浙江理工大学 一种用组织培养法生产甾体生物碱的碱含量测定方法
WO2016046375A1 (en) * 2014-09-25 2016-03-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Theobroma cacao extract for use in the treatment or prevention of receptor tyrosine kinases related disorders
CN106244515A (zh) * 2016-08-04 2016-12-21 福建省农业科学院农业工程技术研究所 一种提高刺葡萄细胞培养物花青素含量的方法
FR3061176B1 (fr) 2016-12-22 2020-09-11 Antofenol Preparation d'un extrait de biomasse seche riche en polyphenols
CN112243860B (zh) * 2020-10-27 2021-05-25 中国科学院昆明植物研究所 一种云南梧桐组培快繁方法
EP4176710A1 (de) 2021-11-03 2023-05-10 Zürcher Hochschule Für Angewandte Wissenschaften Verfahren zur verarbeitung von zellkulturen von kakaopflanzen und dadurch erhaltene produkte

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Publication number Priority date Publication date Assignee Title
CN106109512A (zh) * 2016-06-27 2016-11-16 郭迎庆 一种可可多酚咀嚼片的制备方法
CN114126400A (zh) * 2019-06-07 2022-03-01 马斯公司 可可细胞悬浮方案
CN114126400B (zh) * 2019-06-07 2024-02-23 马斯公司 可可细胞悬浮方案
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Also Published As

Publication number Publication date
US8568798B2 (en) 2013-10-29
EP2414509B1 (de) 2015-09-23
EP2414509A1 (de) 2012-02-08
KR20160054015A (ko) 2016-05-13
KR20120059451A (ko) 2012-06-08
US20120021080A1 (en) 2012-01-26
JP2012522504A (ja) 2012-09-27
JP2015109863A (ja) 2015-06-18
BRPI0925040A2 (pt) 2015-07-21
WO2010114567A1 (en) 2010-10-07
JP5789595B2 (ja) 2015-10-07
EP2414509A4 (de) 2012-10-17
EP2966165A1 (de) 2016-01-13

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Application publication date: 20120411