CN102389476A - Traditional Chinese medicinal preparation for treating stomach cancer and lung cancer and preparation method thereof - Google Patents
Traditional Chinese medicinal preparation for treating stomach cancer and lung cancer and preparation method thereof Download PDFInfo
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- CN102389476A CN102389476A CN201110366346XA CN201110366346A CN102389476A CN 102389476 A CN102389476 A CN 102389476A CN 201110366346X A CN201110366346X A CN 201110366346XA CN 201110366346 A CN201110366346 A CN 201110366346A CN 102389476 A CN102389476 A CN 102389476A
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating the stomach cancer and the lung cancer and a preparation method thereof. An effective component of the traditional Chinese medicinal preparation is prepared from the following traditional Chinese medicinal raw medicines, by weight, 1-12 parts of Hedyotis diffusa, 1-15 parts of Radix Euphorbiae Ebractealatae, and 1-5 parts of jujube. The preparation method comprises the following steps: 1, crushing Hedyotis diffusa and Radix Euphorbiae Ebractealatae, and mixing them according to above proportions; 2, removing peel and core from jujube, adding water, crushing, and uniformly mixing the crushed jujube with the crushed Hedyotis diffusa and Radix Euphorbiae Ebractealatae; 3, steaming for 1h on water; 4, carrying out natural ventilation drying; and 5, filling capsules. The preparation of the invention, which has a simple and practical formula and is a pure traditional Chinese medicinal preparation, has the advantages of low price, and good curative effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation side thereof of treating gastric cancer and pulmonary carcinoma.
Background technology
Gastric cancer is a kind of common malignancy, sends out the age well just in time to be in and to get into the important critical point of life-prolonging when 50～60 years old, so be the Radix Clematidis Clarkeanae that the mankind stride into seventy years of age.
Gastric cancer quietly is mingled in many gastropathy, the early discovery not a duck soup.Particularly the early symptom of gastric cancer and a lot of gastropathy are similar, also may not expect it being cancerous protuberance even seek medical advice, thereby delay treatment is missed opportunity of early treatment.
Discover that according to physicians the early signal of gastric cancer has: 1, indescribable loss of appetite or epigastrium are uncomfortable; 2, often epigastrium is swollen, and needs to alleviate behind the heating installation repeatedly, with especially obvious after the feed; 3, random dull pain of epigastrium or of short duration angor; 4, nauseating, constipation or diarrhoea are often arranged after the feed too much; 5, detest meat abnormally; 6, the losing weight of unknown cause, body are tired weak; 7, can not find the anemia of reason.These signals one or several ground over a period to come alternately occur repeatedly.The more important thing is, be that symptom was not alleviated after general gastropathy was taked treatment when finding these signals and takeing for, just should be especially vigilant, perhaps be gastric cancer!
What deserves to be mentioned is that if be the equiprobable precancerous lesion of chronic gastritis, gastric ulcer when cancerating into gastric cancer, an obvious characteristics of early signal promptly is the rule or the symptom of original gastropathy, has largely to change.The common sympton of gastric cancer has: stomachache, loss of appetite, and become thin and lose weight, feel sick, vomiting, acid regurgitation, heartburn sense, hemorrhage, melena, diarrhoea etc., there is the patient of these symptoms should in time arrive examination in hospital and treats.
Our said pulmonary carcinoma is meant the malignant tumor that comes from bronchus (bronchial) or bronchioles (bronchiolar) epidermis cell (epithelial cell), has accounted for the 90-95% of pulmonary parenchyma malignant tumor.
Pulmonary carcinoma is the first place of the whole world cancer cause of the death at present, nineteen ninety-five the whole world have 600,000 people to die from pulmonary carcinoma, and annual number is all rising.And the women obtains the trend that the incidence rate of pulmonary carcinoma especially has rising.Primary disease is many in morbidity more than 40 years old, and the age of onset peak is between 60～79 years old.Men and women's prevalence is 2.3: 1.Race, family members' history and smoking are all influential to the morbidity of pulmonary carcinoma.
Pulmonary carcinoma originates from the bronchial mucosa epithelium and is confined to that the person is called the cancer in situ cancerous protuberance in the basement membrane, can be in bronchial lumen or/and the lung tissue of closing on growth and can be through lymph blood capable or shift diffusion through bronchus.The carcinoma speed of growth has certain relation with the situation that shifts diffusion and the biological characteristicses such as histological type differentiation degree of carcinoma.
The distribution situation right lung of pulmonary carcinoma is more than left lung, and last leaf all cancerous protuberance can take place more than inferior lobe from the main bronchus to the bronchioles.The pulmonary carcinoma position of originating from the main bronchus lobar bronchi is called central type carcinoma of lung near the hilus pulumonis person; The pulmonary carcinoma position of originating from below the segmental bronchi is called property pulmonary carcinoma on every side peripheral part person of lung.
The cause of disease of pulmonary carcinoma is still not exclusively clear and definite so far, and great mass of data shows that the risk factor of pulmonary carcinoma comprises smoking (comprising second hand smoking), asbestos, radon, arsenic, ionizing radiation, halogen alkene class, polycyclic aromatic, nickel etc.
Pulmonary carcinoma is what characteristic symptom not in early days, is merely the common symptom of general respiratory system disease, like cough, expectorant blood, low grade fever, chest pain, unhappy etc., is easy to ignore.
The concrete manifestation of the early stage common sympton of pulmonary carcinoma:
1. cough.Pulmonary carcinoma, can produce the respiratory tract symptom usually and irritable cough takes place at the broncho-pulmonary tissue because of long.
2. low grade fever.Tumor often has the obstructive lobe of the lung to exist after blocking bronchus, degree varies, and the lighter only has low grade fever, and weight person then has hyperpyrexia, can temporarily take a turn for the better after the medication, but can recur again very soon.
3. chest pain with distension sensation.The early stage chest pain of pulmonary carcinoma is lighter, mainly shows as vexed pain, dull pain, position not necessarily, and is also uncertain with the relation of breathing.Continue generation like distending pain and explain that then cancer has the possibility of involving pleura.
4. expectorant blood.The tumor inflammation has hemorrhage on a small quantity when causing necrosis, blood capillary breakage, often mix with expectorant, is intermittently or interrupted the appearance.A lot of lung cancer patients are gone to a doctor because of expectorant blood.
Pulmonary carcinoma symptom in late period has:
1. face, cervical region edema.On the mediastinum right side superior vena cava is arranged, it will fail back heart from the venous blood of upper limb and incidence.If tumor is invaded and mediastinum right side compressing superior vena cava, first meeting makes jugular vein because of refluxing smooth angry opening, and also can cause face, cervical region edema at last, and this need be able to diagnosis in time and handle;
2. hoarseness is common sympton.The recurrent laryngeal nerve of control left side function of pronunciation comes downwards to chest by cervical region, and the trunk of walking around heart returns row upwards to larynx, thus the left side of domination phonatory organ.
3. tachypnea, the patients with lung cancer of generation area property diffusion nearly all has tachypnea in various degree.Return liquid by lung and the normal structure liquid that cardiac muscle produces by mid-thoracic lymph node.If these lymph nodes are by carcinomatous obstruction, these tissue fluids will accumulate in to form pericardial effusion in the pericardium or accumulate in and form hydrothorax in the thoracic cavity.More than two kinds of situation all can cause tachypnea.Yet because of many smoking patients merge chronic lung disease in various degree, this brings certain difficulty for the discriminating of tachypnea.In addition, because a part of lung tissue has tumor to lose respiratory function because of long, thereby just make a respiratory function impaired and produce and breathe uncomfortablely, originally this sense of discomfort only produces when motion, finally also can feel during rest.
Extensively shift the symptom of pulmonary carcinoma: because metastasis takes place in pulmonary carcinoma very easily in early days, thereby the symptom relevant with metastasis first symptom of finding of doctor or patient often.If focus is transferred to brain, then can produce persistence and have a headache, look dim.Continue development and possibly cause confusion even epilepsy.The character of this headache and common tension headache do not have significant difference, are therefore very easily ignored by people.Blurred vision mainly show as read the newspaper or see TV feel the difficulty.Because most of patients with lung cancer is the old people, they often take for only need themselves and change glasses, and its key is the change of vision character.Change to consciousness and vision is highstrung at first.
If cancer metastasis then can cause bone destruction to bone, when being corrupted to a certain degree, osteodynia also produces thereupon.If outer hard cortical bone is destroyed, then can make bony structures extremely unstable.Betide the had sense of discomfort of rib, but, then also very easily fracture in the daily routines if betide the bigger long bone of load such as femur or humerus.
At last, also be the most thorny, promptly the transfer of spinal column has taken place in pulmonary carcinoma.In Most patients, the spinal column transfer takes place can cause pain.But problem is that cancer can further be transferred to spinal cord.This will at first show as backache, and that continues reaches lower limb, and weakness of the lower extremities, gatism can be arranged, and finally can cause branchpoint following position paralysis.Therefore, severe smoking patient also should cause enough attention if backache occurs.
In current scientific and technical develop rapidly, be accompanied by many science and technology researchs to cancer, as from gene mutation, reverse immune dysfunction.But several kinds of modes in the western medical treatment cancer are excisions, radiotherapy, chemotherapy, and cooperate western medicine, Western medicine aspect the treatment cancer, weak curative effect, cure rate is low, side effect is high, expense is high.Cause the patient more painful.
And a kind of simple, practical, the Chinese medicine preparation that can treat gastric cancer and pulmonary carcinoma simultaneously also useless now.
Summary of the invention
The technical issues that need to address of the present invention just are to overcome existing treatment gastric cancer or pulmonary carcinoma expensive, cure rate is low, income the is low patient's difficulty and high cost of getting medical defective with the misery of bearing high expense and health; A kind of Chinese medicine preparation and preparation side thereof of treating gastric cancer, pulmonary carcinoma is provided; Its prescription is simple and practical; Be a kind of pure Chinese medicinal preparation, low price, good effect.
For addressing the above problem, the present invention adopts following technical scheme:
The invention provides a kind of Chinese medicine preparation of treating gastric cancer and pulmonary carcinoma, the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 1-12 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 1-15 part, Fructus Jujubae 1-5 part.
Perhaps, the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 1-6 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 1-5 part, Fructus Jujubae 1-3 part.
Perhaps, the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 6-12 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5-15 part, Fructus Jujubae 3-5 part.
Perhaps, the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, 8 parts of Herba Hedyotidis Diffusaes, 9 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 3 parts in Fructus Jujubae.
The present invention discloses the method for preparing of said Chinese medicine preparation, Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) mixed by pulverizing the back than row, Fructus Jujubae is removed the peel enucleation after; With the broken back of pigment and Herba Hedyotidis Diffusae and the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) mix homogeneously pulverized; Water proof steaming and decocting 1 hour, after gravity-flow ventilation is dried, the fill capsule.
Among the present invention, Herba Hedyotidis Diffusae heat clearing away, dampness removing, detoxifcation.Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) cough with dyspnea, removing mass compotation food, cold and heat aqueous vapor.The Fructus Jujubae invigorating the spleen and replenishing QI, hard will is powerful, removes unhappy.
This shows that medicament is prepared simply among the present invention, and is with low cost, usage is convenient, can eradicate disease, is a kind of good medicine of patient.
The specific embodiment
Embodiment 1
40 parts of Herba Hedyotidis Diffusaes, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) are mixed after pulverizing than row for 45 parts, after 15 parts of peelings of Fructus Jujubae enucleation, with the Herba Hedyotidis Diffusae and the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) mix homogeneously of broken back of pigment and pulverizing, water proof steaming and decocting 1 hour, after gravity-flow ventilation is dried, the fill capsule.
The heavy 0.25g of every of capsule, every day the 2-8 grain, 3 months is a course of treatment.
Press the method for embodiment 1, preparation the following example: unit: weight portion
| Herba Hedyotidis Diffusae | The Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) | Fructus Jujubae | |
| Embodiment 2 | 1 | 15 | 1 |
| Embodiment 3 | 12 | 1 | 5 |
| Embodiment 4 | 1 | 5 | 1 |
| Embodiment 5 | 6 | 1 | 3 |
| Embodiment 6 | 6 | 15 | 3 |
| Embodiment 7 | 12 | 5 | 5 |
It is 2% solution for effective ingredient concentration that embodiment 2-7 can process injection, injects the 100-300 milliliter every day, and 7-15 days is a course of treatment.
Atmiatry, 2-3 capsule heating obtains steam, sucks 20-30 minute at every turn, cooperates oral capsule treatment pulmonary carcinoma, and 7-15 days is a course of treatment.
Treatment example treatment gastric cancer
Contain * *, man, 58 years old, Yuhang, Hangzhou town, first visit time: on June 25th, 2008.
Medical history:
No obvious inducement diet is not smooth before patient Yu Si month, companion's abdominal distention, and upper right abdomen pain is felt sick; Vomiting, amount is few, and vomitus is a gastric content, becomes thin; Go to a doctor and get biopsy in Zhejiang Provincial People's Hospital's row gastroscopy: gastric cancer, the row subtotal gastrectomy, operation is smoothly.12 courses of treatment of postoperative chemotherapy are chemotherapeutic period at present, alopecia, and nausea and vomiting, the patient refuses chemotherapy once more, for asking Chinese traditional treatment.
Solution:
Because the huge injury that operation and chemotherapy cause health based on the mechanism of Chinese traditional treatment, reduces the side effect that chemotherapy is brought, basic side's medicine is the Chinese medicine preparation of the embodiment of the invention 1 preparation in view of the patient.The heavy 0.25g of every of capsule, every day the 2-8 grain, 3 months is a course of treatment.
Behind treatment time of this patient treatment, the sensation whole body is happy, does not have special discomfort.Diet obviously increases, weight increase 5 kilograms.Two is just normal.After the band medicine of leaving hospital be in 3-4 course of treatment of treatment, cancer all disappearances now can have been done common housework.
Research shows: Chinese medicine preparation of the present invention is controlled the cancer effect and is focused on promoting flow of QI and blood, stasis-dispelling and pain-killing, the sending down the abnormal ascending QI of being open to the custom, ascending the clear and descending the turbid, food stagnation removing food stagnation; Help to receive and be good for fortune, warming spleen and stomach for dispelling cold, Shu Yang warms up limb, reduces blood viscosity, presses down tumor killing cell; Dissolving tumor body, putrefaction removing and tissue regeneration promoting, the healing skin infection is repaired cicatrix.The centering late gastric cancer has the spleen invigorating sending down the abnormal ascending QI and presses down and tell; Regulating qi-flowing for harmonizing stomach and preventing or arresting vomiting; With foster taste invigorating middle warmer gas; Transporting and transforming nutrients from foodstuff removes the effect of phlegm-damp.Stomach can be received, and spleen can food stagnation removing, and one receives and one disappears, and operation is not stopped, and biochemical gas-liquid must pass in internal organs, and the five internal organs can have this, and six internal organs can be active, the prosperous then people's of taste gas life life and growth in nature.
Show through clinical treatment nearly thousand routine middle and advanced stage gastric cancer curative effects: the middle and advanced stage patient takes the fruit that promptly takes effect in general 5-10 days behind the Chinese medicine preparation of the embodiment of the invention 1 preparation, and mainly show as: vomitting, it is few gently to tell, and appetite takes a turn for the better, and aerofluxus is many, just logical refreshing, painful expand to have disappears; Continue to take medicine, wide the vomitting of diaphragm ended, and dizzy putting down adhered to the March of taking medicine, and the stiff thick recovery of coat of the stomach is thin soft, and spirit is good, has a good complexion, and stomach is received many, the extremity temperature, and body weight increases, and muscle power is strong, can manage housework certainly or resume work; Generally adhere to 2-3 the course of treatment, prognosis of disease, the healthy arrival.Even follow up a case by regular visits to for many years, patient is good and sound in good health.
Treatment pulmonary carcinoma:
Medical record 1: horse xx, man, 60 years old.
The patient makes right pneumonectomy on April 17th, 2002 in my institute, and postoperative pathology is squamous cell carcinoma, and p-t2n1m0 cuts property in the Dragon Boat Festival by stages.Postoperative pleura transudate is a lot of, is courageous and upright through the drain chest fluid.Postoperative played the patient on the 11st day and heating occurs.May 16, chest ct showed a large amount of encapsulated effusions in thoracic cavity, right side.Thoracic surgery invites me to go the consultation of doctors, and disease sees that the patient is out of breath, and heating is off one's feed, and becomes thin lusterless complexion; Soft pulse is sliding, and yellow fur is greasy in vain, and disease belongs in the interior blocked-up chest of damp and hot heresy, and healthy energy is multiple, and patient's expectoration every day bloody pleural fluid 100cc is still out of breath; Hyperhidrosis is received not goodly, and it is poor to sleep, thready pulse, and tongue is greasy less.
With the Chinese medicine preparation treatment of the embodiment of the invention 1 preparation, every heavy 0.25g of capsule, every day the 2-8 grain, 3 months is a course of treatment.
After for oral administration, pathogenic heat are moved back less, and syndrome of deficiency of both qi and yin gradually occurs, and the levelling method of treatment is controlled the plan supplementing QI and nourishing YIN, and the lung heat clearing eliminating carbuncle gathers it altogether.After taking medicine, send out febrile lysis, about the about 50cc of expectoration every day hydrothorax, it is still poor to receive.Continue treatment back body temperature and descend, expectoration hydrothorax amount obviously reduces and is transformed into yellow, and spiritual appetite is gradually good.The treatment that takes traditional Chinese medicine continues.July 9 fiberoptic bronchoscopy: right main bronchus stump 2mm aperture, part granulation fibre object growth.Ultrasound diagnosis on July 19: thoracic cavity, right side pleural thickening, do not see hydrothorax.
After this surplus with top treatment 1 year basically, whole body is all right, no relapse and metastasis.
Present case belongs to the serious symptom pleural fistula, and doctor trained in Western medicine mainly adopts intubated and drained, if but hydrothorax is separation shape or parcel property; Drain is difficulty; The patient who has has to adopt operative repair pleural fistula road, and this is undoubtedly " making the matter worse " to patient, increases the misery of operation for the second time.Adopt treatment by Chinese herbs to tend to obtain special effect, more treatment experience is arranged, cured this type of many cases patient for this type patient.
More than be the serious symptom pulmonary carcinoma case report of long-term surviving of not performing the operation, the report of survival more than 5 years seldom arranged after consulting document serious symptom pulmonary carcinoma, the simple chemotherapy of advanced lung cancer.Above-mentioned case is taken Chinese medicine for a long time after chemotherapy, survival reaches nearly 8 years, point out Chinese medicine preparation of the present invention in treating serious symptom pulmonary carcinoma, its unique effect to be arranged.
The existing breakthrough of zero of we's treatment cancer is answered penetration and promotion, removes to save more valuable life.
What should explain at last is: obviously, the foregoing description only be for clearly the present invention is described and is done for example, and be not qualification to embodiment.For the those of ordinary skill in affiliated field, can also make other multi-form variation or change on the basis of the above description.Here need not also can't give exhaustive to all embodiments.And conspicuous variation of being amplified out thus or change still are among protection scope of the present invention.
Claims (5)
1. Chinese medicine preparation of treating gastric cancer and pulmonary carcinoma, it is characterized in that: the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 1-12 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 1-15 part, Fructus Jujubae 1-5 part.
2. the Chinese medicine preparation of treatment gastric cancer as claimed in claim 1 and pulmonary carcinoma is characterized in that: the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 1-6 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 1-5 part, Fructus Jujubae 1-3 part.
3. the Chinese medicine preparation of treatment gastric cancer as claimed in claim 1 and pulmonary carcinoma is characterized in that: the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, Herba Hedyotidis Diffusae 6-12 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5-15 part, Fructus Jujubae 3-5 part.
4. the Chinese medicine preparation of treatment gastric cancer as claimed in claim 1 and pulmonary carcinoma is characterized in that: the effective ingredient of said Chinese medicine preparation is prepared from following parts by weight of Chinese traditional medicine crude drug, 8 parts of Herba Hedyotidis Diffusaes, 9 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 3 parts in Fructus Jujubae.
5. like the method for preparing of the Chinese medicine preparation of the arbitrary described treatment gastric cancer of claim 1-4 and pulmonary carcinoma; It is characterized in that: Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) are mixed by pulverizing the back than row; After Fructus Jujubae removed the peel enucleation, with the broken back of pigment and Herba Hedyotidis Diffusae and the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) mix homogeneously pulverized, water proof steaming and decocting 1 hour; After gravity-flow ventilation is dried, the fill capsule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405721A (en) * | 2013-08-22 | 2013-11-27 | 张素平 | Pharmaceutical composition for inhibiting tumor metastasis and application thereof |
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2011
- 2011-11-18 CN CN201110366346XA patent/CN102389476A/en active Pending
Non-Patent Citations (2)
| Title |
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| 胡世林，张松，胡奇实: "中医新八在抗肿瘤中的应用", 《中国药业》 * |
| 邵玉英: "邵梦扬运用抗癌中草药的学术思想简介", 《国医论坛》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405721A (en) * | 2013-08-22 | 2013-11-27 | 张素平 | Pharmaceutical composition for inhibiting tumor metastasis and application thereof |
| CN103405721B (en) * | 2013-08-22 | 2015-04-08 | 李健 | Pharmaceutical composition for inhibiting tumor metastasis and application thereof |
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