CN102362872A - Use of Longxinsu Jiaonang in preparation of medicines for treating constipation - Google Patents
Use of Longxinsu Jiaonang in preparation of medicines for treating constipation Download PDFInfo
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- CN102362872A CN102362872A CN2011103798965A CN201110379896A CN102362872A CN 102362872 A CN102362872 A CN 102362872A CN 2011103798965 A CN2011103798965 A CN 2011103798965A CN 201110379896 A CN201110379896 A CN 201110379896A CN 102362872 A CN102362872 A CN 102362872A
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- capsules
- longxinsu
- jiaonang
- constipation
- treating constipation
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Abstract
The invention discloses the use of Longxinsu Jiaonang in the preparation of medicines for treating constipation. Longxinsu Jiaonang which is in form of capsules is prepared from extract of fresh earthworms. The content of the capsules is amorphous powder with a color in a range from grey white to yellowish and has hygroscopicity; and the capsules with a fish smell are capable of promoting blood circulation and activating meridians, and therefore can be used for treating ischemic stroke which is caused by blood stasis obstructing the collaterals and has the symptoms of paralysis of half of body, limb numbness and facial paralysis. Each capsule contains 0.15 grams of content. The capsules are for oral administration. Longxinsu Jiaonang is taken by one capsule each time, three times a day. The capsules are required to be taken with warm boiled water and are found to be capable of treating constipation.
Description
Technical field
The present invention relates to a kind of new purposes of Chinese patent medicine, relate in particular to the application of imperial heart cellulose capsule in preparation treatment constipation medicine.
Background technology
Constipation is a kind of commonly encountered diseases, and clinical main performance stool is dry and hard for a long time, defecates once in many days, separates just difficulty misery at every turn, other disease of initiation easily of a specified duration.Its pathogenic factor, traditional Chinese medical science analysis-by-synthesis are thought, because the hot savoury of surfeit too much drink down to accumulated heat in gastrointestinal tract, or after the typhoid fever calentura, waste heat is reluctant to leave, deficiency of body fluid causes intestinal scorching; Because feelings will is not relaxed, quantity of motion reduces, depression and stagnation of QI, logical fall not normal, the conduction dereliction of duty; Because the overstrain internal injury, after being ill, married woman's puerperal or old man's deficiency of both QI and blood, Tianjin is withered can not fail cloth, can not moisten large intestine, and it is not normal unable etc. to cause large intestine to conduct, and can both cause astriction.The method of traditional treatment constipation, the traditional Chinese medical science adopt " DACHENGQI TANG ", Radix Et Rhizoma Rhei more, Folium Sennae, and the stool of removing heat by catharsis such as magnesium sulfate, still dry and hard after the recurrence within the next few days; Doctor trained in Western medicine adopts " phenolphthalein sugar " relieving constipation more, or alleviates with " Kai Saitong ", and existing takes stopgap measures can not effect a permanent cure, and curative effect is unstable, and cure rate is lower, is generally 20%, is prone to the defective of recurrence.The product effect of treatment constipation at present is all not so good, therefore is badly in need of a kind of Chinese medicine of treating constipation.Dragon heart cellulose capsule is the exclusive product of Yongan, Yunnan pharmaceutical Co. Ltd, does not also have the bibliographical information of its treatment constipation at present.
Summary of the invention
Goal of the invention: the object of the present invention is to provide the application of imperial heart cellulose capsule in preparation treatment constipation medicine.
Technical scheme: the application of imperial heart cellulose capsule in preparation treatment constipation medicine.
Dragon heart cellulose capsule is prepared from fresh Pheretima extract, is capsule, and content is canescence to little yellow amorphous powder, and tool draws moist; The gas raw meat can promoting blood circulation to remove obstruction in the collateral, is used for the cerebral infarction due to the obstruction of collaterals by blood stasis, and disease is seen hemiplegia, numb limbs and tense tendons, facial hemiparalysis, specification are every dress 0.15g, and be oral, one time 1,3 times on the one, warm water delivery service is found it at present and can be treated constipation after meal.
Beneficial effect: imperial heart cellulose capsule treatment constipation, respond well.
The specific embodiment
Dragon heart cellulose capsule is to mice with constipation intestinal propulsion motional effects
1. animal, medicine, reagent: animal: healthy ICR mice, male and female half and half, heavy 18-22g is provided production licence number SCXK (Shanghai) 2003-0003 by Shanghai Slac Experimental Animal Co., Ltd..Dragon heart cellulose capsule, Yongan, Yunnan pharmaceutical Co. Ltd, lot number: 20110323; R-1132, Wujin pharmaceutical factory, 20100421.Phenolphthalein tablets (phenolphthalein sugar-tablet), Junan, Shandong Province pharmaceutical factory, specification: 100mg*100 sheet/box, lot number 20100306
2. experimentation: get 60 of ICR mices, irritate the stomach modeling with R-1132 50m/kg, continuous 10 days, during normal diet; Form the constipation model, random packet, every group about 10, male and female half and half; Be divided into normal group, model group, positive drug group (giving phenolphthalein tablets), high, medium and low three dose groups of imperial heart cellulose capsule, administration is the same; Successive administration 14d, fasting can't help water 12h, 2h after the last administration before the experiment; Using volume fraction respectively is that 5% charcoal end arabic gum suspension 1ml/g irritates clothes, puts to death behind the 20min and respectively organizes mice, cuts open the belly and measures every Mus small intestinal charcoal end displacement and small intestinal total length; Be converted into charcoal end displacement and account for the percentage rate of small intestinal total length, group difference is judged in the t check, and the result sees table 1.
The imperial heart cellulose capsule of table 1 is to mice with constipation intestinal propulsion motional effects (n=10)
Compare with model group,
*P＜0.01
*##P＜0.01#P＜0.05 is compared with the positive drug group in P＜0.05
The result: imperial heart cellulose capsule and model group are relatively; Obvious promotion mice with constipation intestinal propulsion motion is arranged, promote the mice gastrointestinal motility, have significant difference; Compare with positive drug; Dragon heart cellulose capsule senior middle school dose groups is promoting to have significant difference aspect the motion of mice with constipation intestinal propulsion, and effect is better than positive drug, explains that it has the effect of treatment constipation.
Claims (1)
1. the application of imperial heart cellulose capsule in preparation treatment constipation medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103798965A CN102362872A (en) | 2011-11-25 | 2011-11-25 | Use of Longxinsu Jiaonang in preparation of medicines for treating constipation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103798965A CN102362872A (en) | 2011-11-25 | 2011-11-25 | Use of Longxinsu Jiaonang in preparation of medicines for treating constipation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102362872A true CN102362872A (en) | 2012-02-29 |
Family
ID=45689488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103798965A Pending CN102362872A (en) | 2011-11-25 | 2011-11-25 | Use of Longxinsu Jiaonang in preparation of medicines for treating constipation |
Country Status (1)
| Country | Link |
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| CN (1) | CN102362872A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840798A (en) * | 2015-05-28 | 2015-08-19 | 陈爱华 | Soft capsules for treating constipation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58126770A (en) * | 1982-01-16 | 1983-07-28 | Kiwako Kosuge | Preparation of powdered healthy food of earthworm |
| CN1718086A (en) * | 2005-07-28 | 2006-01-11 | 王锦 | Honey for treating astriction, regulating functions of intestines and stomach, beautifying and cleaning intestine |
-
2011
- 2011-11-25 CN CN2011103798965A patent/CN102362872A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58126770A (en) * | 1982-01-16 | 1983-07-28 | Kiwako Kosuge | Preparation of powdered healthy food of earthworm |
| CN1718086A (en) * | 2005-07-28 | 2006-01-11 | 王锦 | Honey for treating astriction, regulating functions of intestines and stomach, beautifying and cleaning intestine |
Non-Patent Citations (1)
| Title |
|---|
| 张肇富: "蚯蚓粉健康食品", 《世界科学》, no. 1, 31 December 1993 (1993-12-31), pages 9 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840798A (en) * | 2015-05-28 | 2015-08-19 | 陈爱华 | Soft capsules for treating constipation |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120229 |