CN103285145B - Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof - Google Patents

Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof Download PDF

Info

Publication number
CN103285145B
CN103285145B CN201310189457.7A CN201310189457A CN103285145B CN 103285145 B CN103285145 B CN 103285145B CN 201310189457 A CN201310189457 A CN 201310189457A CN 103285145 B CN103285145 B CN 103285145B
Authority
CN
China
Prior art keywords
preparation
radix
semen
pig
chinese medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201310189457.7A
Other languages
Chinese (zh)
Other versions
CN103285145A (en
Inventor
易凌霄
董伟
孙志良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hunan Agricultural University
Original Assignee
Hunan Agricultural University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunan Agricultural University filed Critical Hunan Agricultural University
Priority to CN201310189457.7A priority Critical patent/CN103285145B/en
Publication of CN103285145A publication Critical patent/CN103285145A/en
Application granted granted Critical
Publication of CN103285145B publication Critical patent/CN103285145B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a pure traditional Chinese medicine preparation for prompting rapid growth of pigs. Each part of preparation comprises fried astragalus root, codonopsis pilosula nnannf, roasted bighead atractylodes rhizome, angelica, radix rehmanniae preparata, cimicifugae foetidae, spina date seed, roasted hovenia dulcis, bunge cherry seed, desertliving cistanche, platycodon grandiflorum, fructus cannabis, peach kernel, almond, pinenut kernel, chrysoidine and radix trichosanthis. The invention further discloses a preparation method and an application method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation has the functions of tonifying qi, engendering liquid, lubricating the intestines, prompting digestion, calming and soothing the nerves, the traditional Chinese medicine preparation mainly improves the digestion function of animal bodies on feed to increase the nutrient substances absorbed by the animal bodies, reduces the movements of the animals and locates the animals at quiet and comfortable states to reduce energy consumption and make more nutrient substances in the animal bodies to participate in an anabolic reaction in the animal bodies so as to reduce the feed conversion ratio while improving the growth speed of the pigs. The application method of the preparation is simple and convenient to operate and is free of unfavorable stimulation on the pigs. The preparation is applied in the application method to ensure an excellent treatment effect and is an excellent pure traditional Chinese medicine preparation for prompting pig growth.

Description

A kind of promote pig to grow fast pure Chinese medicinal preparation and preparation method and using method
Technical field
The present invention relates to veterinary drug technical field, be specially a kind of promote pig to grow fast pure Chinese medicinal preparation and preparation method and using method.
Background technology
In industrial pig industry, the speed of growth of pig is one of key factor determining industrial benefit.Pig growth is pig picked-up feedstuff Middle nutrition composition in essence and the nutritional labeling it absorbed assimilates into the process of its body tissue.Therefore the speed of growth of pig depend on its nutritional labeling absorbed number, thus to search for food to pig and the forage volume that effectively digests (can be absorbed by pig after digestion) is directly proportional.Because the appetite of pig is by negative-feedback regu-lation, so the digestion power positive correlation of the feed intake of pig and pig.
Current, under industrial pig pattern, the feed intake of pig and all undesirable to the digestive efficiency of feedstuff.Pig feed intake deficiency is ubiquitous problem, and general pig is searched for food to full just stopping very likely and searched for food, and pig digestion is slow, and a phenomenon of of having a rest appears eating in the fattening pig on even many pig farms.The feedstuff-meat ratio of pig also remains high, and the feedstuff-meat ratio of pig is general all 3.0 :more than 1.Therefore, industrial pig industry is increasing pig industry benefit still having larger space by improving pig feed intake and reducing the feedstuff-meat ratio of pig.
What the feedstuff-meat ratio improving pig feed intake and reduction pig was commonly used has following method:
One, increase a bit peppery pig appetite depressed time, feed that to order Fructus Piperis powder, Fructus Capsici etc. very effective.Because Fructus Piperis powder, Fructus Capsici contain pungent taste and fragrance, and irritant, gastrointestinal secretion thing can be made after pig feed to increase, thus accelerate gastrointestinal peristalsis, improve digestion power.Especially lactating sow adds a little Fructus Piperis powder etc. in material, not only can increase the feed intake of sow, can also reduce the sickness rate of piglet, impels piglet to wean in advance.
Two, feed a bit sweetly adds appropriate glucide more in the feedstuff of pig, and growing and fattening pigs are liked to eat, and eat rear plump and sturdy; Nursing sow is more liked to eat, and eating rear appetite increases, and prevents phenomenons such as losing flesh, thin and weak, also can increase lactation amount; Piglet prefers sweet taste, can not only survival rate high, and wean is early, and body weight significantly increases.General every kilogram of feed adds 150 ~ 200 milligrams.With good conditionsily add a little white sugar in late spring, late summer, early autumn, early spring, late fall and winter add a little brown sugar, and every kilogram of feed adds 1 ~ 3 gram, and effect is better than glucide.
Three, have some again and salty in swine rations, add appropriate salt (every day is no more than 6 grams), pig metabolism and growth promoter can be promoted, increase amount of drinking water, improve the palatability of feedstuff, appetite stimulator, help digest.
Four, do not forget to add sour every kilogram of feed and add a vinegar 10 milliliters (thin up also can), stir, not only pig is liked to eat, aid digestion, contains the nutritional labelings such as aminoacid because of vinegar, very helpful to pig growth and development, but addition is too much unsuitable.
But these methods are mainly set about in feedstuff palatability, there is certain effect for the feedstuff that palatability is poor, even if but eat many, if digestive efficiency is low, a large amount of feed nutrient is also most discharges with feces.Although improve feed intake, feedstuff-meat ratio also improves thereupon, loses more than gain.Pig industry benefit to be improved by the material meat improving pig feed intake and reduction pig and just must improve pig digestive and absorptive functions by conditioning pig QI and blood.
Summary of the invention
Technical problem solved by the invention is to provide a kind of pure Chinese medicinal preparation promoting pig to grow fast, and it is the pure Chinese medicinal preparation of the promotion pig growth of being made up of pure Chinese prescription, and the present invention additionally provides preparation method and the using method of said preparation simultaneously.Said preparation takes pure Chinese prescription, does not add other compositions of any interpolation in preparation process, thus not containing any harmful components.Said preparation using method is easy and simple to handle, to pig without pessimal stimulation.Said preparation is evident in efficacy with the application of this using method, is a kind of excellent promotion pig growth pure Chinese medicinal preparation.
Technical problem solved by the invention realizes by the following technical solutions:
Promote the pure Chinese medicinal preparation that pig grows fast, every part of preparation comprises following Chinese herb and quality: Radix Astragali Preparata: 6-30g, Radix codonopsis pilosulae (Radix Codonopsis): 10-36g, Rhizoma Atractylodis Macrocephalae (parched): 24-48g, Radix Angelicae Sinensis: 6-24g, Radix Rehmanniae Preparata: 12-42g, Rhizoma Cimicifugae: 6-18g, Semen Ziziphi Spinosae: 6-24g, Fructus Aurantii (parched): 6-18g, Semen Pruni: 6-30g, Herba Cistanches: 6-36g, Radix Platycodonis: 5-18g, Fructus Cannabis: 6-24g, Semen Persicae: 5-30g, Semen Armeniacae Amarum: 6-36g, Semen pini koraiensis: 5-30g, Exocarpium Citri Rubrum: 5-24g, Radix Trichosanthis: 5-24g.
Preferably, every part of preparation comprises following Chinese herb and quality: Radix Astragali Preparata: 12-18g, Radix codonopsis pilosulae (Radix Codonopsis): 10-20g, Rhizoma Atractylodis Macrocephalae (parched): 25-35g, Radix Angelicae Sinensis: 10-18g, Radix Rehmanniae Preparata: 24-30g, Rhizoma Cimicifugae: 6-10g, Semen Ziziphi Spinosae: 6-12g, Fructus Aurantii (parched): 6-10g, Semen Pruni: 6-10g, Herba Cistanches: 6-12g, Radix Platycodonis: 5-15g, Fructus Cannabis: 10-15g, Semen Persicae: 5-10g, Semen Armeniacae Amarum: 10-15g, Semen pini koraiensis: 5-12g, Exocarpium Citri Rubrum: 5-10g, Radix Trichosanthis: 5-10g.
In raw material of the present invention, effect of each composition is as follows:
The pharmacological action of Radix Astragali Preparata mainly contains:
The Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
The pharmacological action of Radix codonopsis pilosulae (Radix Codonopsis) mainly contains:
1. improve animal activity ability: with Radix codonopsis pilosulae's cream to mouse stomach, mice burden swimming ability can be significantly improved.
2. improve reactivity of organism: after taking Radix codonopsis pilosulae's cream to mice, be placed in 45-47 DEG C in case, administration group obviously extended than the matched group time-to-live, showed that this product can improve the resistant to elevated temperatures ability of animal.
3. promote macrophage function: day, to mouse gavaging 0.25g Radix codonopsis pilosulae (Radix Codonopsis) soft extract, is used in conjunction two weeks, and can make 131 I markization plasma protein colloidal solids of quiet note, speed of cleaning up in blood is obviously accelerated, and shows that reticuloendothelial cell phagocytic function strengthens.
4. the effect of pair blood and hemopoietic system: Radix codonopsis pilosulae's soft extract can make rabbit RBC number raise, leukocyte count declines, and neutrophil number increases relatively.Lymphocyte reduces relatively, and oral result is especially good.This product also can increase content of hemoglobin.After excision spleen, effect obviously reduces.But this effect is lasting, stop administration after 20 days, each composition of blood all recovers level before administration.
5. raise blood sugar: to rabbit 6g/kg gavage, can make blood glucose obviously raise.To mouse peritoneal injection 0.5g, also can raise blood sugar.Mouse experiment also shows, drug administration by injection has antagonism to hypoglycemic reaction caused by insulin, and the hyperglycemia caused epinephrine is then without impact.This effect is relevant with contained sugar.
6. pair cardiovascular effect: Radix codonopsis pilosulae's cream has temporary hypotensive effect to large rabbit, but blood pressure recovers rapidly.Obvious antagonism is had to adrenergic booster reaction.
The pharmacological action of Rhizoma Atractylodis Macrocephalae (parched) mainly contains:
The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, quench the thirst, antiabortive." pharmacological action relevant to Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI effect for adjusting gastrointestinal motility function, antiulcer, protect the liver, enhancing human body immunity function, anti-stress, the effect such as enhancing hemopoietic function; Its dampness diuretic effect is relevant with diuresis; And antiabortive effect is relevant with the effect of suppression uterine contraction.The Rhizoma Atractylodis Macrocephalae also has the effects such as antioxidation, slow down aging, blood sugar lowering, anticoagulation, antitumor.
The pharmacological action of Radix Angelicae Sinensis mainly contains:
The pharmacological action of Radix Angelicae Sinensis; mainly contain cardioprotection, arrhythmia, atherosclerosis myocardial infarction; suppress smooth muscle; antiplatelet aggregation; antiinflammatory action; enhancing human body immunity function; the protection of cerebral ischemia; antitumor; make cell proliferation; the research of the effect such as the liver protecting and kidney modern pharmacology further demonstrates Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling, the effects such as pain relieving of enriching blood, and also find, Radix Angelicae Sinensis has antiinflammatory, scavenging activated oxygen, hepatic cholagogic, protection kidney, strengthens the effects such as immunologic function simultaneously.
The pharmacological action of Radix Rehmanniae Preparata mainly contains:
1, on the impact of medulla hematopoietic system: Radix Rehmanniae Preparata water decoction gavages every 0.5g to posthemorrhagic anemia mice, every day 1 time, continuous 10 days, the recovery of anemia animal erythrocyte, hemoglobin can be promoted, accelerate propagation, the differentiation of pluripotential hemopoietic stem cell (CFU-S), bone marrow hemopoietic progenitor cell of red blood cell line (CFU-E).
2, on the impact of blood coagulation: Radix Rehmanniae Preparata can significantly suppress liver hemorrhagic necrosis stove and simple necrosis.To the hyperlipemia that high lipid food causes, the hepatic vein hemorrhage that fatty liver and rat endotoxin cause, all has the effect of inhibition thrombosis.Thinking activation to plasminogen, is antithrombotic mechanism of action.
3, on immune impact: Radix Rehmanniae Preparata alcohol extract, to mouse gavaging, has significant protective effect to the macrophage function suppressed by carrageenin; Antagonist forms cell inhibitory action.
4, on the impact of cardiovascular system: wine Radix Rehmanniae Preparata and cook Radix Rehmanniae and have significant hypotensive effect, systolic pressure and diastolic pressure all significantly decline.
5, antioxidation.
6, other effects: give rat with trilute (T3) and cause yin-deficient model and give Radix Rehmanniae Preparata water decoction 3ml (70% concentration) gavage, totally 6 days, the body weight of hyperthyroidism type deficiency of YIN rat is changed, 24 hours amounts of drinking water and urine volume, blood plasma T3, thyroxine (T4) and aldosterone (AD) concentration are significantly improved, namely T3 concentration reduces, T4 concentration raises, and be tending towards normal, illustrate that Radix Rehmanniae Preparata can not only improve deficiency of YIN symptom, and the thyroxin state of energy dysregulation.
The pharmacological action of Rhizoma Cimicifugae mainly contains:
1. the effect of pair cardiovascular system: Rhizoma Cimicifugae water extract is injected in animal blood pressure lowering, suppress the effect of cardiac muscle, decreased heart rate.Cimicifuga Dahurica can reduce blood pressure, and strengthens heart beating amplitude and does not affect its rhythm and pace of moving things.
2. antibacterial action: in vitro Rhizoma Cimicifugae can suppress the growth of tubercule bacillus.The water logging agent (1:4) of its mutation greenery Rhizoma Cimicifugae Cimicifuga foetida L. var. simplex Huth. all has inhibitory action in various degree to dermatophytess such as being permitted blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore tinea bacterium, epidermophyton rubrum in vitro.Have report to point out, Rhizoma Cimicifugae has stronger inhibitory action to staphylococcus aureus, anthrax bacillus; Also inhibitory action is in various degree had to group B streptococcus, diphtheria corynebacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli, dysentery bacterium.
3. calm, anticonvulsant action: Rhizoma Cimicifugae water extract has sedation, can resist the convulsions that Camphora or strychnine cause in white mice experiment.The central nervous system of Cimicifuga Dahurica to animal also has sedation, Hesperetic acid contained by it can make animal movement slow, be tending towards calm, toxicity is also more weak.
4. antipyretic cooling effect: Cimicifuga Dahurica extract or Hesperetic acid all can make rat normal body temperature decline, and have remarkable refrigeration function to rat fever caused by typhoid fever, paratyphoid fever mixed vaccine. Rhizoma Cimicifugae extract, cimicifugoside also have cooling effect to laboratory animal.
5. the effect of pair smooth muscle: Rhizoma Cimicifugae water extract can suppress intestine in vitro and gravid uterus is excitation to bladder and unpregnancy uterus; Cimicifuga Dahurica can relax intestinal smooth muscle; Bronchus and gastral glandular secretion can also be strengthened; Contraction is had to uterus. also have report to point out, furan chromone derivant kairine (Khellin) has obvious spasmolysis to smooth muscle (bladder, uterus etc.), and furan chromone class is the main active of Rattleroot rhizome.
6. other effects: the methanolic extract of Rhizoma Cimicifugae can prevent the animal liver of Carbon Tetrachloride Induced from damaging effectively.
The pharmacological action of Semen Ziziphi Spinosae mainly contains:
1, calm, syngignoscism.To rat, oral or lumbar injection all behaves with composure and somnolence Semen Ziziphi Spinosae decoct, at no matter daytime or night, normal condition or coffee, because of the excitatory state caused, Semen Ziziphi Spinosae all can show above-mentioned effect, calm index when white mice is oral is 1.95, shows synergism with barbiturate, Semen Ziziphi Spinosae continuous application 6 days, animal sleep can be made to shoal, decreased duration, namely produces toleration, but drug withdrawal can disappear after 1 week.Oral Semen Ziziphi Spinosae can make defensive type motion trained reflex number of times significantly reduce, and interior suppression diffusion, trained reflex disappears, and suppresses the manic phenomenon that cat is caused by morphine.The sedation of raw Semen Ziziphi Spinosae and Semen Ziziphi Spinosae (parched) indistinction, but raw Semen Ziziphi Spinosae effect is more weak, then lost efficacy for a long time, and had and think that the effective ingredient of its calmness may be relevant with oil, separately have and think relevant with water-soluble portion after stir-fry oil cake.
2, analgesia, convulsion, cooling effect.Prove that Semen Ziziphi Spinosae decoct 5 gs/kg is injected in intraperitoneal mouse and has analgesic activity with hot plate method, no matter mice is injected or orally all has cooling effect, but can not antagonistic experiment galvanic shock.
The pharmacological action of Fructus Aurantii (parched) mainly contains:
1. the effect of pair tracheal smooth muscle: Neosynephrine has the effect of stronger expansion trachea and bronchus.Anesthetized cat intravenous injection completely to the bronchoconstriction caused by antihistamine, can also have same effect to guinea-pig isolated trachea.
2. antihemagglutination: rat takes composition Nobiletin in Fructus Aurantii, has and suppresses hematoblastic agglutination, have obvious anti-thrombosis function to rat, and the dosage of 3.2mg/kg is obviously strong than acting as of heparin (132 units/kg).
3. antitumaous effect: Nobiletin is 3-28 μ g/ml to the median effective dose of nasopharyngeal carcinoma KB cell, in body to Mice Bearing Lewis Lung Cancer and Wa Ke carcinoma 256 also effective.
4. antiinflammatory, antifungic action: the ED25 that Nobiletin Ungar method records antiinflammatory is 20mg/kg, and antiinflammatory intensity is 50 units/g.Stronger inhibitory action is had to DeuterophomaTCMLIBacheiphila fungus.
5. the effect in pair uterus: the fistula of uterus of Fructus Aurantii decoct to unpregnancy and pregnant rabbit isolated uterine, uterus in place and unpregnancy rabbit all has obvious excitation, and the uterine contraction rhythm and pace of moving things can be made to increase.But to mice isolated uterine, no matter pregnant or unpregnancy part plays inhibitory action.
The pharmacological action of Semen Pruni mainly contains:
1. the effect of intestinal tube: Semen Pruni has the significant effect promoting enterokinesia.Survey it in little enteral advance distance method with charcoal end, discovery is compared to the pharmacological research that 6 kinds of Semen Pruni class medical materials carry out, the most direct in order to Prunus humilis, Semen Pruni to the work of mice bowel movement.Water extract is the most remarkable, and fatty oil takes second place, and the Aqueous extracts of ethanol extract and ether extract, alcohol extraction is all without obvious effect.And 6 kinds of Semen Prunis are except Amygdalus mongolicus Maxim. promotes that small intestinal peristalsis effect is lower slightly, other are all extremely remarkable.On the impact of constipation, the most remarkable with dryness accumulated in the stomach and intestine type anti-constipation effect.2. the effect of respiratory system: contained by this product, the glycosides of soap has the effect that bronchial mucosa is secreted, for oral administration then have expectorant effect.Organic acid also has Antitussive and Expectorant Effect.Contained amygdaloside can produce the hydrocyanic acid of trace in vivo, and be sedation (low dose of oral) to respiratory center, make breathing be tending towards quiet and reach antitussive and antiasthmatic effect, heavy dose then easily causes poisoning.3. anti-inflammatory and analgesic effect: have people to raise two kinds of protein components from Semen Pruni Aqueous extracts.Intravenous injection, respectively when 20 mg/kg and 0.5 more than mg/kg, all has the activity of inflammation-inhibiting to rat joints of foot edema, during to mouse mainline, press down pain rate and be respectively 61.0% and 61.5%.4. other effects: the tincture made with Semen Pruni, to have reduced blood pressure remarkable effect to test Canis familiaris L..This product also has anticonvulsant action, blood vessel dilating effect.
The pharmacological action of Herba Cistanches mainly contains:
1, anti-aging effects: at delay skin aging, enhancing human body immunity.Gavage Herba Cistanches polysaccharides mice, lung and erythrocyte sod activity have and improve in various degree, and lung and contents of mda reduce.Herba Cistanches polysaccharides can increase the breeder reaction of mice spleen, thymic lymphocytes, and lymphocytic emiocytosis IT-2 under spleen can be significantly improved.Herba Cistanches polysaccharides obviously can promote the growth of human fibroblasts in vitro.The ethanol extraction of Herba Cistanches 95% can make the active obviously enhancing of the SOD in Mice Body, and can reduce the content of myocardium lipofuscin.Obviously can extend life span of drosophila melanogaster, median lethal natural law and maximum life span.Physical stress ability can be improved, directly or indirectly eliminate the infringement of radical pair body, suppress Type B monoamine oxidation vigor, thus slow down aging.
2, immunity moderation effect: the Aqueous extracts of Herba Cistanches, obviously can strengthen cytophagous ability in mouse peritoneal, increase hemolysin and PEC (plaque forming cells) value, immune organ (thymus, spleen) weight can be made to increase, HTdR mixes lymphocytic amount to be increased, and the mice delayed hypersensitivity of sheep red blood cell (SRBC) sensitization strengthens.Herba Cistanches polysaccharides can not only make animal survival time extend, and reduces dead, and obviously can suppress the reduction of CH50 (complement valency).
3, anti-stress and strong effect: the Ergota steroid in Herba Cistanches, Herba Cistanches A and C can enhancing immunity.Herba Cistanches has Andrin-like action, and infers that Ergota steroid may be the main active of its androgen-like action.With the vigor of rat " kidney-yang deficiency model " Serum LDH Isozyme for observation index, from regulating the angle of organism metabolism, the result that Herba Cistanches is investigated is shown, by " insufficiency of kidney-YANG " group that cellulose acetate hydrogen flower cortisone is caused, LDH2-4 vigor obviously increases, and the vigor of LDH5 obviously declines, the low LDH5 of yang deficiency animal after medication, can be made to be tending towards normal with the LDH4 increased.To mix the method for DNA in HTdR body, measuring the DNA synthetic ratio of " insufficiency of kidney-YANG " animal model, find that Herba Cistanches can significantly improve the DNA synthetic ratio of " yang deficiency " mice, playing strong effect by adjusting the ribose metabolism of " yang deficiency animal ".
4, the effect of Endocrine system: Herba Cistanches polysaccharides can promote that the cell of hypophysis part increases, and promotes the secretion of ovary progestogen, can also strengthen the expression of gonad axis estrogen receptor, progesterone receptor, suppress the IL-2 of ovary and interstitial.
The pharmacological action of Radix Platycodonis mainly contains:
1. phlegm-dispelling functions: Radix Platycodonis decoct is to after the oral 1g/kg of anesthetized dog, and respiratory tract mucilage secretion amount can be made significantly to increase, and action intensity is similar to ammonium chloride.Anesthetized cat is also had to the effect promoting respiratory tract mucilage secretion.Its mechanism is that can stimulate gastric mucosa, cause mild nausea, reflexive causes bronchus body of gland secretion increasing due to Saponin contained in Radix Platycodonis, dilution sputum, and plays phlegm-dispelling functions.
2. antitussive effect: use guinea pig trachea stimulus method, kikyosaponin 15mg/kg has antitussive effect. and rough kikyosaponin is to anaesthetized guinea pig lumbar injection, and its half antitussive effective dose ED50 is 6.4mg/kg, points out it to have stronger antitussive effect.
3. antiinflammatory action: kikyosaponin has stronger antiinflammatory action to acute and chronic inflammatory disease.Oral 1/10 ~ 1/5LD50 the dosage of kikyosaponin, has inhibitory action to the foot swelling of Rat Carrageenan colloidality, acetic acid foot swelling; Orally be less than 1/10 LD50 dosage, the formation swollen to rat granuloma also has remarkable inhibitory action; Also effective to rat assist agent arthritis.
The pharmacological action of Fructus Cannabis mainly contains:
1. on the impact of digestive system: pockmarks core has discharge function to mice, every day gavage once, successive administration significantly can increase mice 2 hours defecation frequencies after 4 days.MAREN RUANJIAONANG can increase fecal grains and the weight of normal or dryness accumulated in the stomach and intestine type Constipation Model mice.Maziren Wan and MARENJIAONANG all significantly can increase Bufo siccus intestinal contents weight, increase rabbit at body intestinal segment shrinkage amplitude, but on peristalsis frequency without obvious impact; 20% pockmarks Renhe MARENJIAONANG 4 g/kg gavage, advances charcoal end in mice intestinal and has no significant effect.And capsule defecating feces excretion is better than tablet, and in dose-effect relationship.And MAREN RUANJIAONANG to promote in mouse small intestine and large intestine charcoal end ahead running percentage rate, can increase isolated ileum segments in guinea pigs smooth muscle under physiological status with the motor capacity under low temperature state.The motional amplitude of rabbit at body intestinal is also strengthened to some extent.In Fructus Cannabis, also there is the mechanism of action identical with MAREN RUANJIAONANG.
2. the effect of couple central nervous system: have analgesia, reduce animal spontaneous activity, convulsion, reduces animal heat and affects the effect of distinguishing property of animal escape reaction and learning capacity.Fructus Cannabis extract 100 mg/kg lumbar injection can strengthen and extend Duration of analgesic action, can strengthen and extend syngignoscism and the time for falling asleep of soluble hexobarbital, and the mice that electricity irritation vola can be suppressed to cause enrages behavior; 500 mg/kg lumbar injections can strengthen the central excitation effect of subcutaneous injection amfetamine; 500 mg/kg lumbar injections can cause mice catalepsy shape, and effect is similar to haloperidol.
3. on the impact of cardiovascular system: Fructus Cannabis tincture goes ethanol to be made Emulsion application, and give 2 g/kg in anesthetized cat duodenum, after half an hour, blood pressure starts slow decline, and about being about down to former horizontal half after 2 hours, the rhythm of the heart and breathing have no significant change.Normal rat coloclysis 2 g/kg and 10 g/kg blood pressures also can significantly reduce.Fructus Cannabis can obviously stop rat blood serum cholesterol to raise.Matched group feeds high lipid food, and administration group adds 10% Fructus Cannabis dry product on the basis of feeding high lipid food, and experimental session is often organized and got hematometry cholesterol once on an empty stomach, and result shows that Fructus Cannabis has the effect stoping rat blood serum cholesterol to raise.The mouse ear that 5 g/kg, 15 g/kg that gavage gives Fructus Cannabis alcohol extraction suppress dimethylbenzene to cause swells, and the mice pedal swelling that angle fork Lay causes and the mouse writhing reaction that acetic acid causes for several times, but do not extend the incubation period of burning pain irritant reaction.The thrombus formation time cause electricity irritation rat carotid artery or clotting time have prolongation tendency, do not affect prothrombin time and KPTT.
4. other: Fructus Cannabis can reduce level of serum testosterone, reduces the density of sperm in seminal fluid.Tetrahydrocannabinol can suppress the motility of human spermatogoa.Inject the mice of Fructus Cannabis in advance, increase, morphine withdrawal syndrome to the intake of morphine, Syndrome of Morphine Dependent rat has Some substitute to arrive the effect substituting morphine completely between During The Withdrawal Period.Fructus Cannabis oil has effect for reducing fat.
The pharmacological action of Semen Persicae mainly contains:
Primipara's uterine contraction can be promoted; There are anticoagulant and stronger haemolysis, effect is improved to blood flow retardance, blood obstacle; Cerebral blood flow can be increased, expansion rabbit ear blood vessel; Be sedation to respiratory center; Fatty oil has the effect of intestine moistening laxation.
The pharmacological action of Semen Armeniacae Amarum mainly contains:
1, antitussive, antiasthmatic effect: containing amygdaloside in Semen Armeniacae Amarum, amygdaloside can be hydrolyzed by the emulsin contained by enteric microorganism enzyme or Semen Armeniacae Amarum itself in vivo, produce hydrocyanic acid and the benzaldehyde of trace, have inhibitory action to respiratory center, reach antitussive, antiasthmatic effect.
2, to the effect of digestive system: the Semen Armeniacae Amarum bitter in the mouth therapeutic method to keep the adverse QI flowing downwards, and fatty oil is rich in.Fatty oil can improve the lubrication of intestinal contents to mucosa, therefore Semen Armeniacae Amarum has the function of loosening bowel to relieve constipation.
3, antiinflammatory, analgesic activity: amygdaloside decomposes the benzaldehyde quiet Benzoinum condensing enzyme effect produced and generates Benzoinum.Benzoinum has analgesic activity, and therefore the domestic people of having can remove the misery of patient with Semen Armeniacae Amarum treatment advanced liver cancer, and even not needing of having takes analgesic.
4, antitumor action: about the research of Semen Armeniacae Amarum antitumor machanism mainly contains following several respects: 1. a part of scholar thinks that, containing a large amount of beta-glucosidase in cancerous cell, this enzyme can be hydrolyzed amygdaloside and produce hydrocyanic acid (HCN), benzaldehyde and glucose.Generate enzyme because cancerous cell lacks sulfur nitrile, this enzyme has the Detoxication to HCN, makes the sulfur nitrile compound that HCN becomes nontoxic, and normal cell lacks beta-glucosidase and generates enzyme containing a large amount of sulfur nitriles.According to this theory, amygdaloside should be able to kill cancerous cell by selectivity, and almost harmless to normal cell.2. amygdaloside can help body endotrypsin to digest the mucoprotein film of transparent sample of cancerous cell, makes the more accessible cancerous cell of leukocyte in body, and engulfs cancerous cell.3. someone finds that similar NaSCN and NaOCN of amygdaloside can affect thymidine and enter liver tumor cell DNA and tumor cell to phosphate and amino acid whose absorption.
5, hypoglycemic activity: amygdaloside has the effect of the diabetes that control causes because of antineoplastic agent alloxan.Adopt alloxan to bring out mice hyperglycemia method to prove, survey blood glucose after lumbar injection 3g/kg amygdaloside 48h in advance, result shows that amygdaloside can suppress the blood glucose caused by alloxan to raise specifically, and action intensity is relevant with the concentration of amygdaloside in blood.
6, effect for reducing blood fat: clinical report, jordan almond obviously can reduce the blood lipid level of hyperlipemic patients, Spiller(1990) think in Semen Armeniacae Amarum monounsaturated fatty acid and contribute to and reduce the blood fat that patient slightly raises, and without the need to strict dietary restriction.
7, beautification function: theoretical according to lung associating with skin and hair, can control from lung qi dispersing method opinion some dermatosis clinically, compatibility eats Semen Armeniacae Amarum, often obtains prompt effect.Modern study proves, fatty oil contained in Semen Armeniacae Amarum can make keratodermatitis soften, and moisturizes skin protection, has the effect of neuroprotective peripheral vessel and histoorgan, but and can kill antibacterial.In addition, the HCN that generates by enzyme hydrolysis can suppress in body active tyrosine enzyme, eliminate pigmentation, freckle, black speck etc., thus reach the effect of beauty treatment.
8, other effects: amygdaloside has antimutagenic effect, can reduce the quantity of the micronucleus polychromatic erythrocyte caused by dipyrone, metronidazole, ametycin etc.Semen Armeniacae Amarum oil also has anthelmintic, bactericidal action, and in vitro tests has killing effect to ascariasis, Lumbricus, and has antibacterial action to typhoid fever, Salmonella paratyphi.Semen Armeniacae Amarum also has anti-pinworm and trichomonacide, the effect for the treatment of aplastic anemia.
The pharmacological action of Semen pini koraiensis mainly contains:
1. normal edible Semen Pini can building body, has extraordinary adjuvant treatment effect especially to oldaged physically weak, lumbago, the symptom such as dizzy.
2. Semen Pini both can tonify Qi of the kidney, enriching blood for moistening the intestine, have can healthcare, can also angiocardiopathy preventing, have good curative effect to night sweat, constipation simultaneously.
3. in Semen Pini, vitamin E has the effect of good vessel softening, slow down aging up to 30%.
4. phosphorous abundanter in Semen Pini, have and strengthen brain cell metabolism, safeguard the effect of function of brain cell, often eat the clever saying of Semen Pini so just have.
5. Semen pini koraiensis is rich in fatty oil especially, and eat Semen pini koraiensis can its effect to nourishing YIN and moistening the lung, laxation relieving constipation more.
The pharmacological action of Exocarpium Citri Rubrum mainly contains:
Pungent; Bitter; Temperature.Return bladder; Small intestinal; Lung; Spleen; Large intestine; Stomach warp.Cure mainly cold expelling dampness; Activating QI to eliminate phlegm; Alleviating distention in middle-JIAO stomach invigorating.Main cough due to wind and cold; Abundant expectoration QI rising in reverse order; Nausea and vomiting; Breast gastral cavity painful abdominal mass is swollen.
The pharmacological action of Radix Trichosanthis mainly contains:
1. cause miscarriage and antiearly pregnancy effect.
2. on immune impact
A. immunostimulation: Radix Trichosanthis energy enhancing human body immunity function, facilitation is had to the formation of spleen immunocyte and differentiation, make the white pulp composition comparatively matched group had significant proliferation of mouse spleen, germinal center increases, edge is broadening, IgM, B lymphocyte and the plasmacytic quantity showed increased of IgG, macrophage areal area also expands to some extent.Trichosanthin can stimulate immunity system, makes body produce the IgE antibody of variola amyloid proteins.Anemia of pregnant woman injects trichosanthin can activate mother's immune system, can remove the immunosuppressive condition of anemia of pregnant woman, is a kind of nonspecific immunity strengthening agent.And the anaphylaxis that Radix Trichosanthis preparation occurs, be also a kind of immunostimulation.
B. immunosuppressive action: trichosanthin has inhibitory action to humoral immunization, C57BL/6N mice is accepting the front trichosanthin first injecting various dose for 1 day of anaphylactogen ovalbumin inoculation, by the comparative observation Radix Trichosanthis of PCA titre on the impact of IgE antibody tormation, result shows: all low than matched group with the generation of the IgE antibody of the pretreated mice of trichosanthin, the trichosanthin of 1 μ g/25g Mus just has obvious inhibit activities, and 2 responses after booster immunization show more remarkable. trichosanthin is immunoreation capable of inhibiting cell also, with the splenocyte of C57BL/6J mice, lymphocyte and thymocyte cell carry out in vitro cell culture, find that the pouring that trichosanthin can suppress concanavalin A (Con-A) or phytohaemagglutinin (PHA) to bring out turns, and inhibition strength is directly related with dosage.
3. antitumaous effect: trichosanthin has good curative effect to trophoblastic cell tumor.Lumbar injection 5mg/kg, has certain therapeutical effect to mouse experiment liver ascites, can reduce ascites volume, extends survival period.Also slight inhibitory action is had to transplanted hepatoma solid tumor.The propagation of trichosanthin to human liver cancer cell has inhibitory action, and its effect increases with dosage and strengthens.But this suppression is reversibility.
4. the biosynthesis of Profilin matter: trichosanthin has the effect suppressing Toad Oocytes protein synthesis, effect link is in translation skill.It is also a very strong inhibitor to the translation system of the protein synthesis in vitro that rabbit reticulocyte lysate is formed.Radix Trichosanthis has the very strong DNA replication dna of HIV inhibiting (HIV) and the effect of protein synthesis.Radix Trichosanthis shows strong Profilin matter biosynthesis power in cell free system, and it is active in reduce the ricin that ftractures through sulfhydryl reagent suitable.
5. other effects: Radix Trichosanthis decocting liquid (1:1) has certain inhibitory action to Hemolytic streptococcus, Diplococcus pneumoniae and diphtheria corynebacterium in vitro; More weak to the effect of staphylococcus aureus and other multiple pathogenic bacillus.
QI invigorating of the present invention helps fortune, intestine moistening of promoting the production of body fluid, facilitating digestion, strengthens and absorbs, mind tranquilizing and the heart calming.The nutrient substance of animal body picked-up is improved mainly through improving the digestive and absorptive functions of animal body to feedstuff, benefiting vital QI for tranquillizing simultaneously, animal is made to reduce motion, be in quiet easypro state, reduce energy expenditure, more nutrient substance in animal body can be made to participate in the anabolic reaction in animal body, can while raising growth speed of pigs, (pure Chinese medicinal preparation that promotion pig of the present invention grows fast comprises said dosage form on any one pharmaceutics to reduce feedstuff-meat ratio.)。
The preparation method of above-mentioned pure Chinese medicinal preparation, comprises following processing step:
(1) accurately Chinese herb is taken by above-mentioned Chinese medicine formula;
(2) Chinese medicine weighing up weight is put into rustless steel container with cover;
(3) add distilled water, and the mass ratio of the distilled water added and Chinese medicine is 5:1;
(4) slow fire boiling 1 hour;
(5) after pouring out medicine juice, then by 1 :5(mass ratio) Chinese medicine and water add distilled water, namely repeat the process of (3);
(6) slow fire boiling abandoned medicinal residues after 1 hour, was merged by the medicine juice of twice results in front and back;
(7) medicine juice is put 50 DEG C of baking ovens, within 72 hours, dry to gelatin;
(8) the abundant stirring and evenly mixing of 450g starch is added.
The using method of above-mentioned pure Chinese medicinal preparation: in each stage pig feed spice, add above-mentioned pure Chinese medicinal preparation 2-5kg in complete feedstuff per ton, fully mix thoroughly and feed.
The present invention takes pure Chinese prescription, does not add any other composition in preparation process, thus not containing any harmful components, is a kind of green short long functional preparation.Said preparation using method is easy and simple to handle, to pig without pessimal stimulation.Said preparation is evident in efficacy with the application of this using method, by contrast experiment, proves that product growth-promoting effect of the present invention is remarkable, no matter all shows significant effect from the speed of growth or feedstuff-meat ratio aspect.Experimental group average daily gain exceeds matched group average daily gain 6.2%; Experimental group feedstuff-meat ratio comparatively matched group feedstuff-meat ratio reduces by 5.8%, and this is all extremely important to reduction aquaculture cost and raising culture benefit.
Detailed description of the invention
The present invention will be described in detail in citing below.
In order to the beneficial effect of technical solution of the present invention is described, carry out administering transgenic.
Embodiment one
Test material
1) experimental animal
200 body weight are selected to be about the large pig of 80kg, require that kind, parity, age, male and female ratio, body weight are close, be divided into 2 groups at random, each group is 100, wherein one group is experimental group (adding Chinese medicine preparation in the ratio of 2 kg/ton to mix thoroughly in daily feedstuff), and other one group is matched group.Often organize 10 one repetitions, often repeat (hurdle) 10 pigs.Wherein, every part of formula of Chinese materia medica preparation is: Radix Astragali Preparata: 6g, Radix codonopsis pilosulae (Radix Codonopsis): 36g, Rhizoma Atractylodis Macrocephalae (parched): 24g, Radix Angelicae Sinensis: 24g, Radix Rehmanniae Preparata: 12g, Rhizoma Cimicifugae: 18g, Semen Ziziphi Spinosae: 6g, Fructus Aurantii (parched): 18g, Semen Pruni: 6g, Herba Cistanches: 36g, Radix Platycodonis: 5g, Fructus Cannabis: 24g, Semen Persicae: 5g, Semen Armeniacae Amarum: 36g, Semen pini koraiensis: 5g, Exocarpium Citri Rubrum: 24g, Radix Trichosanthis: 5g.
This Chinese medicine preparation is prepared by the following method:
(1) accurately Chinese herb is taken by above-mentioned formula;
(2) Chinese medicine weighing up weight is put into rustless steel container with cover;
(3) add distilled water, and the mass ratio of the distilled water added and Chinese medicine is 5:1;
(4) slow fire boiling 1 hour;
(5) after pouring out medicine juice, then by 1 :5(mass ratio) Chinese medicine and water add distilled water, namely repeat the process of (3);
(6) slow fire boiling abandoned medicinal residues after 1 hour, was merged by the medicine juice of twice results in front and back;
(7) medicine juice is put 50 DEG C of baking ovens, within 72 hours, dry to gelatin;
(8) the abundant stirring and evenly mixing of 450g starch is added.
2) daily ration is tested
(1) requirement
By average daily feed intake 3.0kg/ days, test calculating in 45 days, two kinds of test daily rations need respectively: 15000kg
Diet Formula %
test method
1) EXPERIMENTAL DESIGN
Single factor test completely randomized experiment.
2) testing index
(1) body weight
First starting weight: terminate next day in preliminary trial period, early morning weighs on an empty stomach, record W1
Off-test body weight: in off-test day, early morning weighs on an empty stomach, record W3
Average daily gain: (end weight-starting weight) ÷ tests natural law
(2) feed intake
Every hurdle feed intake: record every hurdle daily ingestion amount respectively, before every morning feeding, claims surplus material weight, and according to situation adjustment feeding capacity of searching for food.Note the amount of observing waste material, deduct if should estimate too much.
(3) price of deed
The price of deed: the price of deed=total augment weight ÷ feed intake
3) feeding and management
Selection experiment pig, 5 days preliminary trial periods, completes the transition of test daily ration, viewing test pig health status in preliminary trial period.Just trying 35 days phases, record weighed, feed intake and diarrhea rate.Epidemic prevention process is carried out in unification routinely.
4) data statistic analysis
Available EXCEL software rough estimates data, then carry out statistical analysis with SAS.
Result of the test
Test is carried out the 4th day experimental group and is died of illness one, and within the 7th day, matched group dies of illness one, and following table calculates meat feed ratio and calculates by actual materials gauge, and the quantity calculating daily gain pig calculates by the actual survival in test end pig quantity.
Result of the test
find out from above-mentioned comparative test result: experimental group daily gain 1030 grams, matched group 970 grams, experimental group every pig every day how long 60 grams, difference is very remarkable.
Feedstuff-meat ratio: experimental group 2.91:1, matched group 3.08:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 170 grams of experimental group, difference is extremely remarkable.
Embodiment two
Test material
1) experimental animal
Select 200 body weight to be about the large pig of 70kg, require that kind, parity, age, male and female ratio, body weight are close, be divided into 2 groups at random, each group is 100.One group is experimental group, and (in daily feedstuff, adding Chinese medicine preparation in the ratio of 2 kg/ton mix thoroughly), other one group is matched group.Often organize 10 one repetitions, often repeat (hurdle) 10 pigs.Wherein, every part of formula of Chinese materia medica preparation is: Radix Astragali Preparata 30g, Radix codonopsis pilosulae (Radix Codonopsis): 10g, Rhizoma Atractylodis Macrocephalae (parched): 48g, Radix Angelicae Sinensis: 6g, Radix Rehmanniae Preparata: 42g, Rhizoma Cimicifugae: 6g, Semen Ziziphi Spinosae: 24g, Fructus Aurantii (parched): 6g, Semen Pruni: 30g, Herba Cistanches: 6g, Radix Platycodonis: 18g, Fructus Cannabis: 6g, Semen Persicae: 30g, Semen Armeniacae Amarum: 6g, Semen pini koraiensis: 30g, Exocarpium Citri Rubrum: 5g, Radix Trichosanthis: 24g.
This Chinese medicine preparation is prepared by the following method:
(1) accurately Chinese herb is taken by above-mentioned formula;
(2) Chinese medicine weighing up weight is put into rustless steel container with cover;
(3) add distilled water, and the mass ratio of the distilled water added and Chinese medicine is 5:1;
(4) slow fire boiling 1 hour;
(5) after pouring out medicine juice, then by 1 :5(mass ratio) Chinese medicine and water add distilled water, namely repeat the process of (3);
(6) slow fire boiling abandoned medicinal residues after 1 hour, was merged by the medicine juice of twice results in front and back;
(7) medicine juice is put 50 DEG C of baking ovens, within 72 hours, dry to gelatin;
(8) the abundant stirring and evenly mixing of 450g starch is added.
2) daily ration is tested
(1) requirement
By average daily feed intake 3.0kg/ days, test calculating in 45 days, two kinds of test daily rations need respectively: 15000kg
Diet Formula %
test method
1) EXPERIMENTAL DESIGN
Single factor test completely randomized experiment.
2) testing index
(1) body weight
First starting weight: terminate next day in preliminary trial period, early morning weighs on an empty stomach, record W1
Off-test body weight: in off-test day, early morning weighs on an empty stomach, record W3
Average daily gain: (end weight-starting weight) ÷ tests natural law
(2) feed intake
Every hurdle feed intake: record every hurdle daily ingestion amount respectively, before every morning feeding, claims surplus material weight, and according to situation adjustment feeding capacity of searching for food.Note the amount of observing waste material, deduct if should estimate too much.
(3) price of deed
The price of deed: the price of deed=total augment weight ÷ feed intake
3) feeding and management
Selection experiment pig, 5 days preliminary trial periods, completes the transition of test daily ration, viewing test pig health status in preliminary trial period.Just trying 35 days phases, record weighed, feed intake and diarrhea rate.Epidemic prevention process is carried out in unification routinely.
4) data statistic analysis
Available EXCEL software rough estimates data, then carry out statistical analysis with SAS.
Result of the test
Following table calculates meat feed ratio and calculates by actual materials gauge, and the quantity calculating daily gain pig calculates by the actual survival in test end pig quantity.
Result of the test
find out from above-mentioned comparative test result: experimental group daily gain 1060 grams, matched group 990 grams, experimental group every pig every day how long 70 grams, difference is very remarkable.
Feedstuff-meat ratio: experimental group 2.83:1, matched group 3.03:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 200 grams of experimental group, difference is extremely remarkable.
Embodiment three
Test material
1) experimental animal
Select 200 body weight to be about the large pig of 60kg, require that kind, parity, age, male and female ratio, body weight are close, be divided into 2 groups at random, each group is 100.One group is experimental group, and (in daily feedstuff, adding Chinese medicine preparation in the ratio of 2 kg/ton mix thoroughly), other one group is matched group.Often organize 10 one repetitions, often repeat (hurdle) 10 pigs.Wherein, every part of formula of Chinese materia medica preparation is: Radix Astragali Preparata: 18g, Radix codonopsis pilosulae (Radix Codonopsis): 20g, Rhizoma Atractylodis Macrocephalae (parched): 35g, Radix Angelicae Sinensis: 18g, Radix Rehmanniae Preparata: 30g, Rhizoma Cimicifugae: 10g, Semen Ziziphi Spinosae: 12g, Fructus Aurantii (parched): 10g, Semen Pruni: 10g, Herba Cistanches: 6g, Radix Platycodonis: 5g, Fructus Cannabis: 10g, Semen Persicae: 5g, Semen Armeniacae Amarum: 10g, Semen pini koraiensis: 5g, Exocarpium Citri Rubrum: 5g, Radix Trichosanthis: 5g.
This Chinese medicine preparation is prepared by the following method:
(1) accurately Chinese herb is taken by above-mentioned formula;
(2) Chinese medicine weighing up weight is put into rustless steel container with cover;
(3) add distilled water, and the mass ratio of the distilled water added and Chinese medicine is 5:1;
(4) slow fire boiling 1 hour;
(5) after pouring out medicine juice, then by 1 :5(mass ratio) Chinese medicine and water add distilled water, namely repeat the process of (3);
(6) slow fire boiling abandoned medicinal residues after 1 hour, was merged by the medicine juice of twice results in front and back;
(7) medicine juice is put 50 DEG C of baking ovens, within 72 hours, dry to gelatin;
(8) the abundant stirring and evenly mixing of 450g starch is added.
2) daily ration is tested
(1) requirement
By average daily feed intake 3.0kg/ days, test calculating in 45 days, two kinds of test daily rations need respectively: 15000kg
Diet Formula %
test method
1) EXPERIMENTAL DESIGN
Single factor test completely randomized experiment.
2) testing index
(1) body weight
First starting weight: terminate next day in preliminary trial period, early morning weighs on an empty stomach, record W1
Off-test body weight: in off-test day, early morning weighs on an empty stomach, record W3
Average daily gain: (end weight-starting weight) ÷ tests natural law
(2) feed intake
Every hurdle feed intake: record every hurdle daily ingestion amount respectively, before every morning feeding, claims surplus material weight, and according to situation adjustment feeding capacity of searching for food.Note the amount of observing waste material, deduct if should estimate too much.
(3) price of deed
The price of deed: the price of deed=total augment weight ÷ feed intake
3) feeding and management
Selection experiment pig, 5 days preliminary trial periods, completes the transition of test daily ration, viewing test pig health status in preliminary trial period.Just trying 35 days phases, record weighed, feed intake and diarrhea rate.Epidemic prevention process is carried out in unification routinely.
4) data statistic analysis
Available EXCEL software rough estimates data, then carry out statistical analysis with SAS.
Result of the test
Following table calculates meat feed ratio and calculates by actual materials gauge, and the quantity calculating daily gain pig calculates by the actual survival in test end pig quantity.
Result of the test
find out from above-mentioned comparative test result: experimental group every daily gain in pigs 1310 grams, matched group 1220 grams, experimental group every pig every day how long 90 grams, difference is very remarkable.Feedstuff-meat ratio: experimental group 2.60:1, matched group 2.79:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 190 grams of experimental group, difference is extremely remarkable.
Embodiment four
Experiment material with in experimental technique except the formula of Chinese medicine preparation with embodiment three not identical, other are all identical.The formula of the present embodiment Chinese medicine preparation is: Radix Astragali Preparata: 12g, Radix codonopsis pilosulae (Radix Codonopsis): 10g, Rhizoma Atractylodis Macrocephalae (parched): 25g, Radix Angelicae Sinensis: 10g, Radix Rehmanniae Preparata: 24g, Rhizoma Cimicifugae: 6g, Semen Ziziphi Spinosae: 6g, Fructus Aurantii (parched): 6g, Semen Pruni: 6g, Herba Cistanches: 12g, Radix Platycodonis: 15g, Fructus Cannabis: 15g, Semen Persicae: 10g, Semen Armeniacae Amarum: 15g, Semen pini koraiensis: 12g, Exocarpium Citri Rubrum: 10g, Radix Trichosanthis: 10g.
Comparative test result: experimental group every daily gain in pigs 1290 grams, matched group 1210 grams, experimental group every pig every day how long 80 grams, difference is very remarkable.Feedstuff-meat ratio: experimental group 2.61:1, matched group 2.81:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 200 grams of experimental group, difference is extremely remarkable.
Embodiment five
Experiment material with in experimental technique except the formula of Chinese medicine preparation with embodiment three not identical, other are all identical.The formula of the present embodiment Chinese medicine preparation is: Radix Astragali Preparata: 25g, Radix codonopsis pilosulae (Radix Codonopsis): 26g, Rhizoma Atractylodis Macrocephalae (parched): 37g, Radix Angelicae Sinensis: 18g, Radix Rehmanniae Preparata: 28g, Rhizoma Cimicifugae: 13g, Semen Ziziphi Spinosae: 18g, Fructus Aurantii (parched): 15g, Semen Pruni: 22g, Herba Cistanches: 27g, Radix Platycodonis: 14g, Fructus Cannabis: 16g, Semen Persicae: 24g, Semen Armeniacae Amarum: 30g, Semen pini koraiensis: 24g, Exocarpium Citri Rubrum: 16g, Radix Trichosanthis: 18g.
Comparative test result: experimental group every daily gain in pigs 1320 grams, matched group 1240 grams, experimental group every pig every day how long 80 grams, difference is very remarkable.Feedstuff-meat ratio: experimental group 2.59:1, matched group 2.77:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 180 grams of experimental group, difference is extremely remarkable.
Embodiment six
Experiment material with in experimental technique except the formula of Chinese medicine preparation with embodiment three not identical, other are all identical.The formula of the present embodiment Chinese medicine preparation is: Radix Astragali Preparata: 16g, Radix codonopsis pilosulae (Radix Codonopsis): 15g, Rhizoma Atractylodis Macrocephalae (parched): 30g, Radix Angelicae Sinensis: 15g, Radix Rehmanniae Preparata: 26g, Rhizoma Cimicifugae: 8g, Semen Ziziphi Spinosae: 8g, Fructus Aurantii (parched): 7g, Semen Pruni: 8g, Herba Cistanches: 9g, Radix Platycodonis: 10g, Fructus Cannabis: 12g, Semen Persicae: 7g, Semen Armeniacae Amarum: 12g, Semen pini koraiensis: 7g, Exocarpium Citri Rubrum: 8g, Radix Trichosanthis: 7g.
Comparative test result: experimental group every daily gain in pigs 1318 grams, matched group 1239 grams, experimental group every pig every day how long 79 grams, difference is very remarkable.Feedstuff-meat ratio: experimental group 2.62:1, matched group 2.84:1, often increase weight one kilogram of Carnis Sus domestica, and the few feed consumption 180 grams of experimental group, difference is extremely remarkable.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention; the technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications; these changes and improvements all fall in the claimed scope of the invention, and application claims protection domain is defined by appending claims and equivalent thereof.

Claims (4)

1. the pure Chinese medicinal preparation promoting pig to grow fast, it is characterized in that, every part of preparation is made up of following Chinese herb and quality: Radix Astragali Preparata: 6-30g, Radix codonopsis pilosulae (Radix Codonopsis): 10-36g, Rhizoma Atractylodis Macrocephalae (parched): 24-48g, Radix Angelicae Sinensis: 6-24g, Radix Rehmanniae Preparata: 12-42g, Rhizoma Cimicifugae: 6-18g, Semen Ziziphi Spinosae: 6-24g, Fructus Aurantii (parched): 6-18g, Semen Pruni: 6-30g, Herba Cistanches: 6-36g, Radix Platycodonis: 5-18g, Fructus Cannabis: 6-24g, Semen Persicae: 5-30g, Semen Armeniacae Amarum: 6-36g, Semen pini koraiensis: 5-30g, Exocarpium Citri Rubrum: 5-24g, Radix Trichosanthis: 5-24g.
2. the pure Chinese medicinal preparation that grows fast of promotion pig according to claim 1, it is characterized in that, every part of preparation is made up of following Chinese herb and quality: Radix Astragali Preparata: 12-18g, Radix codonopsis pilosulae (Radix Codonopsis): 10-20g, Rhizoma Atractylodis Macrocephalae (parched): 25-35g, Radix Angelicae Sinensis: 10-18g, Radix Rehmanniae Preparata: 24-30g, Rhizoma Cimicifugae: 6-10g, Semen Ziziphi Spinosae: 6-12g, Fructus Aurantii (parched): 6-10g, Semen Pruni: 6-10g, Herba Cistanches: 6-12g, Radix Platycodonis: 5-15g, Fructus Cannabis: 10-15g, Semen Persicae: 5-10g, Semen Armeniacae Amarum: 10-15g, Semen pini koraiensis: 5-12g, Exocarpium Citri Rubrum: 5-10g, Radix Trichosanthis: 5-10g.
3. promote a preparation method for the pure Chinese medicinal preparation that pig grows fast, it is characterized in that, comprise following processing step:
(1) accurately Chinese herb is taken by the formula in claim 1 or 2;
(2) Chinese medicine weighing up weight is put into rustless steel container with cover;
(3) add distilled water, and the mass ratio of the distilled water added and Chinese medicine is 5:1;
(4) slow fire boiling 1 hour;
(5) after pouring out medicine juice, then by 1 :5(mass ratio) Chinese medicine and water add distilled water, namely repeat the process of (3);
(6) slow fire boiling abandoned medicinal residues after 1 hour, was merged by the medicine juice of twice results in front and back;
(7) medicine juice is put 50 DEG C of baking ovens, within 72 hours, dry to gelatin;
(8) the abundant stirring and evenly mixing of 450g starch is added.
4. promote a using method for the pure Chinese medicinal preparation that pig grows fast, it is characterized in that, in each stage pig feed spice, add the pure Chinese medicinal preparation 2-5kg described in claim 1 or 2 in complete feedstuff per ton, fully mix thoroughly and feed.
CN201310189457.7A 2013-05-21 2013-05-21 Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof Expired - Fee Related CN103285145B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310189457.7A CN103285145B (en) 2013-05-21 2013-05-21 Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310189457.7A CN103285145B (en) 2013-05-21 2013-05-21 Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof

Publications (2)

Publication Number Publication Date
CN103285145A CN103285145A (en) 2013-09-11
CN103285145B true CN103285145B (en) 2015-05-06

Family

ID=49087034

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310189457.7A Expired - Fee Related CN103285145B (en) 2013-05-21 2013-05-21 Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof

Country Status (1)

Country Link
CN (1) CN103285145B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104026341A (en) * 2014-05-16 2014-09-10 安徽蓝博旺现代农业科技有限公司 Alfalfa pig feed containing chocolate residues
CN104171703A (en) * 2014-08-11 2014-12-03 成都巨星农牧科技有限公司 Piglet feed premix for promoting digestion
CN104171707A (en) * 2014-08-12 2014-12-03 成都巨星农牧科技有限公司 Compound piglet feed additive for promoting digestion
CN106858099A (en) * 2017-02-27 2017-06-20 齐芳 A kind of feed for lifting pig lean meat percentage
CN107927402A (en) * 2017-12-27 2018-04-20 安徽省六尺春翠农业科技有限公司 It is a kind of into pannage
CN112273530A (en) * 2020-10-26 2021-01-29 广东加大实业有限公司 Suckling pig milk powder feed and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101579043B (en) * 2009-04-13 2012-05-23 邹振可 Chinese medicinal herb additive for promoting the growth of piglet and application thereof

Also Published As

Publication number Publication date
CN103285145A (en) 2013-09-11

Similar Documents

Publication Publication Date Title
CN103141709B (en) Carp feed and preparation method thereof
CN102178103B (en) Suckling pig feed and preparation method thereof
CN101606632B (en) Health care feed for sow in perinatal period
CN102940155B (en) Duckling feed for cherry valley duck and preparation method thereof
CN102178100B (en) Low-tryptophan feed for hybrid chicken and preparation method of the low-tryptophan feed
CN103734547B (en) Pig feed for promoting growth of piglets and Chinese medicine additive and preparing method of pig feed and Chinese medicine additive
CN103285145B (en) Pure traditional Chinese medicine preparation for prompting rapid growth of pigs as well as preparation method and application method thereof
CN103478508B (en) Chinese medicinal composition and feed for improving chicken immunity and preparation method of composition and feed
CN102205107B (en) Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof
CN104381691A (en) Functional feed for preventing nutritional anemia of piglets and preparation method of functional feed
CN103690919B (en) Medicine being used for the treatment of piglet iron-deficiency anemia and preparation method thereof
CN101579120A (en) Nutritional food with weight-losing function and preparation method thereof
CN103652501A (en) Feed for treating cow mastitis and preparation method thereof
CN105231051A (en) Fattening pig feed for improving meat quality and flavor of pork and preparation method of fattening pig feed
CN102784363A (en) Traditional Chinese medicine composition for treating pancreatic cancer and preparation method thereof
CN104187172A (en) Functional feed for treating enterogastritis diseases of turtles and preparation method of functional feed
CN105231050A (en) Fattening pig feed additive for improving quality and flavor of pork, and preparation method of the feed additive
CN103461585B (en) Qi tonifying and health preserving herbal tea
CN105285400A (en) Fattening-pig feed additive used for improving pork quality and flavor and preparation method thereof
CN104970220A (en) Compound feed for sows in suckling period and preparation method thereof
CN104800771A (en) Traditional Chinese medicine preparation for treating children sleep terror disorder and preparation method thereof
CN103705835B (en) Medicine being used for the treatment of cad pig and preparation method thereof
CN103181557A (en) Nutritious food with slimming function and preparation method thereof
CN102552743A (en) Medicinal composition for treating diabetes and preparation method thereof
CN106266565A (en) The medicine of a kind of toxoplasmosis and the preparation method of this medicine

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150506

Termination date: 20160521