CN103446545A - Traditional Chinese medicine composition for treating chronic atrophic gastritis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating chronic atrophic gastritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis. The traditional Chinese medicine composition comprises the following main components: radix scrophulariae, dendrobe, pseudo-ginseng, radix curcumae, curcuma zedoary, mint, fritillaria cirrhosa and the like. The traditional Chinese medicine composition is obtained through continuous improvement in a plurality of clinical applications. In the composition, the traditional Chinese medicines are combined reasonably, each traditional Chinese medicine not only can work independently but also can draw on strength of each other, the synergistic effect is realized, consequently, the treatment effect is significant; compared with the application of western medicine, the side effect is low, both symptoms and root causes are treated, the cure rate is high, the recurrence rate is low, the irritation to a stomach caused by the treatment of traditional Chinese medicines is less, the load of the stomach is reduced, therefore a patient can also have good appetite during the period of taking the medicine, not only the disease is improved continuously but also the diet is not delayed, in this way, an excellent physical condition of the patient is guaranteed and a good circulation is formed, so as to accelerate the recovery of the condition of the patient.
Description
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine composition and preparation method for the treatment of chronic atrophic gastritis.
Background technology
Chronic atrophic gastritis is a kind of commonly encountered diseases, refers to gastric mucosa loss of function atrophy and changes and give birth to, and often involves cardia, lose and the gastrin secretion minimizing with the G cell, also can involve body of stomach, with the forfeiture of secreting acid gland, cause gastric acid, the minimizing of pepsin and endogenous factors.
The medicine that is used for the treatment of chronic atrophic gastritis has many kinds; Generally be divided into Chinese medicine and Western medicine, adopt the western medicine chronic atrophic gastritis, side effect is larger, and larger to the infringement of human body, therapeutic effect is undesirable; Because Chinese medicine has little, the eutherapeutic characteristics of side effect, therefore favored by people.But the Chinese medicine formula therapeutic effect in currently available technology is not obvious.
Summary of the invention
The problem to be solved in the present invention is for above problem, and a kind of Chinese medicine composition and preparation method for the treatment of chronic atrophic gastritis that cure rate is high, relapse rate is low is provided.
For addressing the above problem, the technical solution adopted in the present invention is:
A kind of Chinese medicine composition for the treatment of chronic atrophic gastritis, get the crude drug of following parts by weight: Radix Scrophulariae 10 grams, Herba Dendrobii 50 grams, Radix Notoginseng 5 grams, Radix Curcumae 40 grams, Rhizoma Curcumae 40 grams, Herba Menthae 5 grams, Bulbus Fritillariae Cirrhosae 5 grams, Succus Bambusae 3 grams, Radix Peucedani 4 grams, Cinnabaris 4 grams, succinum 8 grams, Folium Eriobotryae 7 grams, Gypsum Fibrosum 4.5 grams, Semen Persicae 5.5 grams, the Radix Rehmanniae 7.5 grams, Radix Platycodonis 7.5 grams, Pollen Typhae 8 grams, Oletum Trogopterori 8 grams, Radix Glycyrrhizae 4 grams, Ramulus Cinnamomi 10 grams, Caulis Bambusae In Taenia 10 grams, Rhizoma Phragmitis 30 grams, Fructus Aurantii 10 grams, Radix Ophiopogonis 10 gram, Flos Lonicerae 20 grams, the Radix Pulsatillae 10 grams, Nodus Nelumbinis Rhizomatis 5 grams.
A kind of preparation method for the treatment of the Chinese medicine composition of chronic atrophic gastritis comprises the following steps:
1) get Herba Dendrobii, Radix Notoginseng, Herba Menthae, Bulbus Fritillariae Cirrhosae, Succus Bambusae, Radix Peucedani, Folium Eriobotryae, Semen Persicae, the Radix Rehmanniae, Radix Platycodonis, Pollen Typhae, Oletum Trogopterori, Radix Glycyrrhizae, Ramulus Cinnamomi, Caulis Bambusae In Taenia, Rhizoma Phragmitis, Radix Ophiopogonis, Flos Lonicerae, the Radix Pulsatillae, the Nodus Nelumbinis Rhizomatis of above-mentioned weight portion, add the decocting of 10 times of total raw material medicine weight to boil, leach medicinal liquid, obtain medicinal liquid A;
2) Gypsum Fibrosum of above-mentioned weight portion, Cinnabaris, Succinum powder are broken into to 100 purpose fine powders;
After Radix Scrophulariae, Rhizoma Curcumae, Radix Curcumae, the Fructus Aurantii of 3) getting above-mentioned weight portion extracted volatile oil respectively, the decocting that medicinal residues add up 5 times of crude drug weight boils, and decoction liquor is centrifugal, gets supernatant, obtains extracting solution B;
4) merge above-mentioned medicinal liquid A and extracting solution B, stir, obtain extracting solution C after filtration;
Add step 2 while 5) extracting solution C being heated to 70 degrees centigrade) in fine powder, boil, add step 3 30 minutes) volatile oil that makes, stir, make medicine.
Through clinical trial, the present embodiment has good curative effect to the treatment chronic atrophic gastritis, is difficult for recurrence, and has no side effect, and does not develop immunity to drugs, and be 10 days each course for the treatment of, can cure after taking 2 to 3 courses for the treatment of, and obvious effective rate reaches more than 93%, and relapse rate is lower.
The present invention is through repeatedly clinical use, update and draw, drug matching of the present invention is reasonable, every flavor Chinese medicine can not only be brought into play effect separately, and learn from other's strong points to offset one's weaknesses between each Chinese medicine, synergism, therapeutic effect is remarkable, with the application Western medicine, compare, side effect is little, take stopgap measures and effect a permanent cure, cure rate is high, relapse rate is low, treatment by Chinese herbs is less to the zest of stomach, alleviate the stomach burden, make the patient also good appetite can be arranged at period in a medicine, not only the state of an illness constantly takes a turn for the better, and do not delay diet, guaranteed that the patient has a good body constitution, form a good circulation, and then accelerated the recovery from illness of the state of an illness.
The specific embodiment
Embodiment, get the crude drug of following weight: Radix Scrophulariae 10 grams, Herba Dendrobii 50 grams, Radix Notoginseng 5 grams, Radix Curcumae 40 grams, Rhizoma Curcumae 40 grams, Herba Menthae 5 grams, Bulbus Fritillariae Cirrhosae 5 grams, Succus Bambusae 3 grams, Radix Peucedani 4 grams, Cinnabaris 4 grams, succinum 8 grams, Folium Eriobotryae 7 grams, Gypsum Fibrosum 4.5 grams, Semen Persicae 5.5 grams, the Radix Rehmanniae 7.5 grams, Radix Platycodonis 7.5 grams, Pollen Typhae 8 grams, Oletum Trogopterori 8 grams, Radix Glycyrrhizae 4 grams, Ramulus Cinnamomi 10 grams, Caulis Bambusae In Taenia 10 grams, Rhizoma Phragmitis 30 grams, Fructus Aurantii 10 grams, Radix Ophiopogonis 10 gram, Flos Lonicerae 20 grams, the Radix Pulsatillae 10 grams, Nodus Nelumbinis Rhizomatis 5 grams.
A kind of preparation method for the treatment of the Chinese medicine composition of chronic atrophic gastritis comprises the following steps:
1) get Herba Dendrobii, Radix Notoginseng, Herba Menthae, Bulbus Fritillariae Cirrhosae, Succus Bambusae, Radix Peucedani, Folium Eriobotryae, Semen Persicae, the Radix Rehmanniae, Radix Platycodonis, Pollen Typhae, Oletum Trogopterori, Radix Glycyrrhizae, Ramulus Cinnamomi, Caulis Bambusae In Taenia, Rhizoma Phragmitis, Radix Ophiopogonis, Flos Lonicerae, the Radix Pulsatillae, the Nodus Nelumbinis Rhizomatis of above-mentioned weight in grams, add the decocting of 10 times of total raw material medicine weight to boil, leach medicinal liquid, obtain medicinal liquid A;
2) Gypsum Fibrosum of above-mentioned weight, Cinnabaris, Succinum powder are broken into to 100 purpose fine powders;
After Radix Scrophulariae, Rhizoma Curcumae, Radix Curcumae, the Fructus Aurantii of 3) getting above-mentioned weight extracted volatile oil respectively, the decocting that medicinal residues add up 5 times of crude drug weight boils, and decoction liquor is centrifugal, gets supernatant, obtains extracting solution B;
4) merge above-mentioned medicinal liquid A and extracting solution B, stir, obtain extracting solution C after filtration;
Add step 2 while 5) extracting solution C being heated to 70 degrees centigrade) in fine powder, boil, add step 3 30 minutes) volatile oil that makes, stir, make medicine.
The medicine made is divided into to two parts, and a minute morning and evening takes, and within 10 days, is a course for the treatment of, and can fully recover general 2-3 the course for the treatment of, and period in a medicine is avoided pungent meat or fish.
For further investigating clinical efficacy and the safety of the present embodiment medicine, we have selected the case of 300 routine chronic gastritiss to carry out clinical trial to the treatment curative effect of medicine of the present invention.
The patient of 300 routine chronic atrophic gastritis is divided into to two groups at random, every group of 150 examples.In matched group, male's 70 examples, women's 80 examples; 30～40 years old age, 20 examples, 41～50 years old 52 example, 51～60 years old 47 example, 61～70 years old 28 example, 3 examples more than 70 years old; In treatment group, male's 85 examples, women's 65 examples; 30～40 years old age, 16 examples, 41～50 years old 54 example, 51～60 years old 45 example, 61～70 years old 29 example, 6 examples more than 70 years old.
Two groups of cases are Epidemiological Analysis by statistics at aspects such as sex, age, the courses of disease, has comparability.
Matched group adopts appropriate exercise, and rational diet, adopt traditional Western medicine (hydroxide aluminium flake) to be treated; The oral medicine of the present invention for the treatment of group, divide and take night and morning, and takes 3 courses for the treatment of.
Criterion of therapeutical effect: cure: clinical symptoms, sign disappear, the gastritis transference cure, and stomach is comfortable, has no adverse reaction.Produce effects: clinical symptoms, sign obviously alleviate, and the gastritis symptom obviously alleviates, and the symptom such as have a stomach-ache obviously alleviates, and hemogram is normal.Effectively: clinical symptoms, sign alleviate, the gastritis sx↓.Invalid: clinical symptoms, sign are not improved.Relapse rate: the probability recurred again within 1 year after healing.Curative effect comparision result after two groups of cases are treated is as table one.
Table one
| Group | Number of cases | Cure n (%) | Produce effects n (%) | Effective n (%) | Invalid n (%) | Relapse rate n (%) |
| Matched group | 150 | 110(73.3) | 120(80.0) | 130(86.7) | 20(13.3) | 20(33.3) |
| Treatment group | 150 | 125(83.3) | 140(93.3) | 148(98.7) | 2(1.33) | 13(8.7) |
By above-mentioned contrast, can find out and use treatment by Chinese herbs chronic atrophic gastritis of the present invention, therapeutic effect is remarkable, with the Western medicine of matched group, compares, each index all is better than Western medicine, takes stopgap measures and effects a permanent cure, and cure rate is high, relapse rate is low, and treatment by Chinese herbs is less to the zest of stomach, alleviates body burden.
The present invention has good curative effect to the treatment chronic atrophic gastritis, is difficult for recurrence, and has no side effect, and does not develop immunity to drugs, and be 15 days each course for the treatment of, can cure after taking 2 to 3 courses for the treatment of, and cure rate reaches more than 83.3%, and relapse rate is lower, is only 8.7% left and right.
Some patients were healing case is as follows:
The Qin, man, 40 years old, the frequent distending pain of stomach, the time dull pain or dull pain are arranged, severe pain or angor during outbreak, loss of appetite usually appears, even without appetite, though or appetite feed aftersensation gastral cavilty section's distension discomfort or dyspepsia are arranged, be chronic atrophic gastritis after diagnosing, after giving the present embodiment treatment two courses for the treatment of, patient's transference cure, state of an illness recovery from illness, not recurrence so far.
Zhang, man, 32 years old, because long-time diet is irregular, recently, loss of appetite, usually appear in the scorching hot or noisy discomfort of the conscious gastral cavilty of patient section, even without appetite, be chronic atrophic gastritis after diagnosing, after giving the present embodiment treatment course for the treatment of, patient's transference cure, after strengthening a course for the treatment of, the state of an illness is fully recovered, so far recurrence.
Lee, female 61 years old, long-term stomach acid regurgitation, stomach severe pain or angor during outbreak, be chronic atrophic gastritis after diagnosing, gives the present embodiment after two courses for the treatment of, and patient's symptom disappears substantially, then takes state of an illness recovery from illness after a course for the treatment of, and so far mistake half a year, the state of an illness does not recur.
What certain, man 50 years old, due to drink throughout the year and diet irregular, cause that recent gastral cavilty section is scorching hot, acid regurgitation, and the loss of appetite phenomenon occurs, stomach angor during outbreak, flank is felt distension, and after giving the present embodiment treatment two courses for the treatment of, patient's symptom disappears substantially, and appetite increases, continue to take state of an illness recovery from illness after a course for the treatment of.
Claims (2)
1. a Chinese medicine composition for the treatment of chronic atrophic gastritis is characterized in that: the crude drug of getting following weight grams: Radix Scrophulariae 10 grams, Herba Dendrobii 50 grams, Radix Notoginseng 5 grams, Radix Curcumae 40 grams, Rhizoma Curcumae 40 grams, Herba Menthae 5 grams, Bulbus Fritillariae Cirrhosae 5 grams, Succus Bambusae 3 grams, Radix Peucedani 4 grams, Cinnabaris 4 grams, succinum 8 grams, Folium Eriobotryae 7 grams, Gypsum Fibrosum 4.5 grams, Semen Persicae 5.5 grams, the Radix Rehmanniae 7.5 grams, Radix Platycodonis 7.5 grams, Pollen Typhae 8 grams, Oletum Trogopterori 8 grams, Radix Glycyrrhizae 4 grams, Ramulus Cinnamomi 10 grams, Caulis Bambusae In Taenia 10 grams, Rhizoma Phragmitis 30 grams, Fructus Aurantii 10 grams, Radix Ophiopogonis 10 gram, Flos Lonicerae 20 grams, the Radix Pulsatillae 10 grams, Nodus Nelumbinis Rhizomatis 5 grams.
2. a preparation method for the treatment of the Chinese medicine composition of chronic atrophic gastritis comprises the following steps:
1) get Herba Dendrobii 50 grams, Radix Notoginseng 5 grams, Herba Menthae 5 grams, Succus Bambusae 3 grams, Radix Peucedani 4 grams, Folium Eriobotryae 7 grams, Semen Persicae 5.5 grams, the Radix Rehmanniae 7.5 grams, Bulbus Fritillariae Cirrhosae 7.5 grams, Radix Platycodonis 7.5 grams, Pollen Typhae 8 grams, Oletum Trogopterori 8 grams, Radix Glycyrrhizae 4 grams, Ramulus Cinnamomi 10 grams, Caulis Bambusae In Taenia 10 grams, Rhizoma Phragmitis 30 grams, Radix Ophiopogonis 10 gram, Flos Lonicerae 20 grams, the Radix Pulsatillae 10 grams, Nodus Nelumbinis Rhizomatis 5 grams of above-mentioned weight portion, add the decocting of 10 times of total raw material medicine weight to boil, leach medicinal liquid, obtain medicinal liquid A;
2) Gypsum Fibrosum of above-mentioned weight portion, Cinnabaris, Succinum powder are broken into to 100 purpose fine powders;
After Radix Scrophulariae, Rhizoma Curcumae, Radix Curcumae, the Fructus Aurantii of 3) getting above-mentioned weight in grams extracted volatile oil respectively, the decocting that medicinal residues add up 5 times of crude drug weight boils, and decoction liquor is centrifugal, gets supernatant, obtains extracting solution B;
4) merge above-mentioned medicinal liquid A and extracting solution B, stir, obtain extracting solution C after filtration;
Add step 2 while 5) extracting solution C being heated to 70 degrees centigrade) in fine powder, boil, add step 3 30 minutes) volatile oil that makes, stir, make medicine.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104338109A (en) * | 2014-10-20 | 2015-02-11 | 党广旺 | Traditional Chinese medicine for treating chronic gastritis |
| CN105833224A (en) * | 2016-05-03 | 2016-08-10 | 王青云 | Traditional Chinese medicine for treating chronic gastric disease and preparing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1981860A (en) * | 2005-12-16 | 2007-06-20 | 佛山德众药业有限公司 | Chinese-medicinal composition for treating chronic gastritis and atrophic gastritis and its production |
| CN101940734A (en) * | 2010-09-03 | 2011-01-12 | 荣成市新技术应用研究所 | Traditional Chinese medicine for treating chronic gastritis |
| CN101912564B (en) * | 2010-09-07 | 2011-08-31 | 董宇翔 | Traditional Chinese medicine for treating chronic gastritis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1981860A (en) * | 2005-12-16 | 2007-06-20 | 佛山德众药业有限公司 | Chinese-medicinal composition for treating chronic gastritis and atrophic gastritis and its production |
| CN101940734A (en) * | 2010-09-03 | 2011-01-12 | 荣成市新技术应用研究所 | Traditional Chinese medicine for treating chronic gastritis |
| CN101912564B (en) * | 2010-09-07 | 2011-08-31 | 董宇翔 | Traditional Chinese medicine for treating chronic gastritis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104338109A (en) * | 2014-10-20 | 2015-02-11 | 党广旺 | Traditional Chinese medicine for treating chronic gastritis |
| CN105833224A (en) * | 2016-05-03 | 2016-08-10 | 王青云 | Traditional Chinese medicine for treating chronic gastric disease and preparing method thereof |
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