CN102348719A - 多肽及其用途 - Google Patents
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- CN102348719A CN102348719A CN2009801579165A CN200980157916A CN102348719A CN 102348719 A CN102348719 A CN 102348719A CN 2009801579165 A CN2009801579165 A CN 2009801579165A CN 200980157916 A CN200980157916 A CN 200980157916A CN 102348719 A CN102348719 A CN 102348719A
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Applications Claiming Priority (5)
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| US19392609P | 2009-01-08 | 2009-01-08 | |
| US61/193,926 | 2009-01-08 | ||
| GB0905790.2 | 2009-04-03 | ||
| GBGB0905790.2A GB0905790D0 (en) | 2009-04-03 | 2009-04-03 | Novel polypeptides and use thereof |
| PCT/GB2009/002782 WO2010079314A2 (en) | 2009-01-08 | 2009-11-30 | Novel polypeptides and use thereof |
Publications (1)
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| CN102348719A true CN102348719A (zh) | 2012-02-08 |
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| CN2009801579165A Pending CN102348719A (zh) | 2009-01-08 | 2009-11-30 | 多肽及其用途 |
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| EP (1) | EP2373683A2 (enExample) |
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| GB0607798D0 (en) * | 2006-04-20 | 2006-05-31 | Alligator Bioscience Ab | Novel polypeptides and use thereof |
| US10376595B2 (en) | 2017-04-03 | 2019-08-13 | Inflarx Gmbh | Treatment of inflammatory diseases with inhibitors of C5a activity |
| JP7502865B2 (ja) * | 2017-06-23 | 2024-06-19 | インフラルクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | C5a活性のインヒビターでの炎症性疾患の処置 |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
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| WO2007122400A2 (en) * | 2006-04-20 | 2007-11-01 | Alligator Bioscience Ab | Novel polypeptides and use thereof |
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| US4440859A (en) | 1977-05-27 | 1984-04-03 | The Regents Of The University Of California | Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms |
| US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| IN151589B (enExample) | 1978-12-22 | 1983-05-28 | Biogen Nv | |
| US4530901A (en) | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4678751A (en) | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4766075A (en) | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US4582800A (en) | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4757006A (en) | 1983-10-28 | 1988-07-12 | Genetics Institute, Inc. | Human factor VIII:C gene and recombinant methods for production |
| US4677063A (en) | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US4810648A (en) | 1986-01-08 | 1989-03-07 | Rhone Poulenc Agrochimie | Haloarylnitrile degrading gene, its use, and cells containing the gene |
| CA2072249C (en) | 1991-06-28 | 2003-06-17 | Saiko Hosokawa | Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane |
| AU3559695A (en) | 1994-09-30 | 1996-04-26 | Inex Pharmaceuticals Corp. | Glycosylated protein-liposome conjugates and methods for their preparation |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| GB9712512D0 (en) | 1997-06-16 | 1997-08-20 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| CA2333898A1 (en) | 1998-07-10 | 2000-01-20 | Jari Pharmaceuticals B.V. | Chemotaxis-inhibiting protein of staphylococcus (chips) and its use |
| EP1118663A1 (en) * | 2000-01-07 | 2001-07-25 | Universiteit Utrecht | Nucleic acids encoding chemotaxis inhibitory polypeptides |
| JP4430303B2 (ja) | 2000-12-12 | 2010-03-10 | アリゲーター・バイオサイエンス・アーベー | タンパク質機能のインビトロ分子進化方法 |
| US7262012B2 (en) | 2002-05-17 | 2007-08-28 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations |
| EP1586583A3 (en) | 2004-04-16 | 2005-11-16 | Alligator Bioscience AB (publ) | Compounds that block C5a complement receptor and their use in therapy |
| GB2432366B (en) | 2005-11-19 | 2007-11-21 | Alligator Bioscience Ab | A method for in vitro molecular evolution of protein function |
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2009
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- 2009-11-30 EP EP09768216A patent/EP2373683A2/en not_active Withdrawn
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Patent Citations (1)
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| WO2007122400A2 (en) * | 2006-04-20 | 2007-11-01 | Alligator Bioscience Ab | Novel polypeptides and use thereof |
Non-Patent Citations (1)
| Title |
|---|
| BENT POSTMA ET AL.: "Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor", 《THE JOURNAL OF IMMUNOLOGY》 * |
Also Published As
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| CA2748522A1 (en) | 2010-07-15 |
| US20120071394A1 (en) | 2012-03-22 |
| AU2009336610A1 (en) | 2011-07-14 |
| BRPI0923938A2 (pt) | 2018-10-30 |
| RU2011133060A (ru) | 2013-02-20 |
| JP2012514465A (ja) | 2012-06-28 |
| GB0905790D0 (en) | 2009-05-20 |
| US8552149B2 (en) | 2013-10-08 |
| WO2010079314A3 (en) | 2010-09-10 |
| WO2010079314A2 (en) | 2010-07-15 |
| EP2373683A2 (en) | 2011-10-12 |
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