CN102326590B - Mugwort leaf mosquito incense - Google Patents

Mugwort leaf mosquito incense Download PDF

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Publication number
CN102326590B
CN102326590B CN2011103102747A CN201110310274A CN102326590B CN 102326590 B CN102326590 B CN 102326590B CN 2011103102747 A CN2011103102747 A CN 2011103102747A CN 201110310274 A CN201110310274 A CN 201110310274A CN 102326590 B CN102326590 B CN 102326590B
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mosquito
parts
repellent incense
kilograms
mugwort leaf
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CN102326590A (en
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许银亚
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Suzhou Chencai Textile Research Development Co Ltd
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许银亚
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses mugwort leaf mosquito incense, which consists of the following components in part by weight: 70 to 80 parts of mugwort leaf, 20 to 25 parts of virgate wormwood herb, 3 to 6 parts of lilac daphne flower bud, 1 to 3 parts of Chinese asafetida, 15 to 25 parts of elm bark, 1 to 3 parts of sandalwood, 35 to 40 parts of camphor wood, 1 to 3 parts of mint, 4 to 6 parts of agilawood, 1 to 3 parts of saffron, and 0.5 to 1.5 parts of musk. The mugwort leaf mosquito incense has strong expelling and killing effects on mosquitoes, and does not produce harmful effect on the human body.

Description

Foliu artemisiae argyi type mosquito-repellent incense
Technical field
The present invention relates to a kind of mosquito-repellent incense, relate in particular to a kind of Foliu artemisiae argyi type mosquito-repellent incense.
Background technology
Mosquito-repellent incense is a kind of mosquito repellent thing, and medicine is wherein lighted the rear cigarette that sends can drive mosquito or smoked dead mosquito away.China's very long history that kindles mosquito repellent incense, traditional mosquito-repellent incense are divided two kinds of line spices and incense coils.
Yet the effective ingredient of most of mosquito-repellent incenses is pyrethrin insecticides, and organic filler, binder, dyestuff and other additives etc., therefore contains many harmful materials in the cigarette of mosquito incense burning, might bring out the diseases such as asthma.
Summary of the invention
For above shortcomings in prior art, one of technical problem to be solved by this invention provides a kind of Foliu artemisiae argyi type mosquito-repellent incense, and mosquito is had the stronger effect of killing, and can not produce harmful effect to human body.
The present invention seeks to be achieved through the following technical solutions:
A kind of Foliu artemisiae argyi type mosquito-repellent incense is made of by weight following component: tarragon 70-80 part, oriental wormwood 20-25 part, lilac daphne 3-6 part, asafoetide 1-3 part, elm bark 15-25 part, santal 1-3 part, camphorwood 35-40 part, peppermint 1-3 part, agalloch eaglewood 4-6 part, west safflower 1-3 part, Moschus 0.5-1.5 part.
Preferably, a kind of Foliu artemisiae argyi type mosquito-repellent incense is made of by weight following component: tarragon 70-80 part, oriental wormwood 20-25 part, lilac daphne 3-6 part, asafoetide 1-3 part, elm bark 15-25 part, santal 1-3 part, camphorwood 35-40 part, peppermint 1-3 part, agalloch eaglewood 4-6 part, west safflower 1-3 part, Moschus 0.5-1.5 part, black false hellebore 2-4 part, Radix Codonopsis 0.5-1.5 part.
Chinese medicinal mosquito coil of the present invention can adopt industry conventional method to be prepared from.For example, with above-mentioned each component, be dried and crushed into respectively 80-120 purpose powder, take each component according to proportioning, add water and fully be mixed into mud, mud is put into joss sticks manufacturing machine extrusion molding post-drying, can make Foliu artemisiae argyi type mosquito-repellent incense of the present invention.
Concrete, in the present invention,
Tarragon is the dried leaves of feverfew Chinese mugwort.Be recorded in an one-61 of Pharmacopoeia of the People's Republic of China version in 2005.
Oriental wormwood, this product are the dry aerial parts of feverfew shore wormwood artemisia or Artemisia capillaris.Be recorded in an one-166 of Pharmacopoeia of the People's Republic of China version in 2005.
Lilac daphne is the dry flower of Isolated From Thymelaeaceae Species lilac daphne.Be recorded in an one-109 of Pharmacopoeia of the People's Republic of China version in 2005.
Asafoetide is the resin of samphire Ferula sinkiangensis or Ferula fukanensis K.M.Shen.Be recorded in an one-131 of Pharmacopoeia of the People's Republic of China version in 2005.
Elm bark is dry bark or the root skin of Ulmaceae elm.Be recorded in " the colored atlas of practical Chinese herbal medicine " the 4th, Nationalities Press's " hiding Chinese voluminous dictionary " version in 1985.
Santal is the heartwood of Santalaceae plant santal trunk.Be recorded in an one-264 of Pharmacopoeia of the People's Republic of China version in 2005.
Camphorwood, aiphyllium, the bark yellowish-brown has irregular longitudinal crack, and main product reaches southwestern various places on the south the Changjiang river.Cut down trees winter and split broken or be sawn into bulk, dry or air-dry.The timber bulk is not of uniform size, and surface red is brown to burgundy, the visible annual ring in cross section.Matter is heavy and hard.Strong camphor fragrance is arranged, distinguish the flavor of refrigerant, pungent sense is arranged.
Peppermint, this product are the dry aerial parts of labiate peppermint.Be recorded in an one-261 of Pharmacopoeia of the People's Republic of China version in 2005.
Agalloch eaglewood contains the timber of resin for the Isolated From Thymelaeaceae Species suspension culture of Aquilaria sinensis.Be recorded in an one-128 of Pharmacopoeia of the People's Republic of China version in 2005.
West safflower is the dry column cap of irides Crocus sativus.Be recorded in an one-86 of Pharmacopoeia of the People's Republic of China version in 2005.
Moschus is the dry secretion in the ripe male body note capsule of animal in deer family woods musk deer, horse musk deer or former musk deer.Be recorded in an one-266 of Pharmacopoeia of the People's Republic of China version in 2005.
Black false hellebore (formal name used at school: the Veratrum nigrum L.) plant of Liliaceae Veratrum, perennial herb.Effect: clearing heat and detoxicating, desinsection.Also many places are on the books in one one of Pharmacopoeia of the People's Republic of China version in 2005.
Radix Codonopsis is the dry root of Campanulaceae Radix Codonopsis, element flower Radix Codonopsis or radix codonpsis tangshen.Be recorded in an one-199 of Pharmacopoeia of the People's Republic of China version in 2005.
The present invention is made by the wild Chinese herbal medicine fully, and tarragon, oriental wormwood, lilac daphne and asafoetide are composite, and the smell that distributes in combustion process can suppress, the kill virus germ, and the prevention respiratory disease strengthens immune function of human body, mosquito killer; The powder that elm bark, santal and camphorwood are made makes mosquito-repellent incense moulding and the double burning matrix of doing, and santal, camphorwood, peppermint, agalloch eaglewood, west safflower and Moschus are in combustion process, fresh air not only, and can be antibacterial except poison, especially effective mosquito killer, more crucial is to use for a long time the present invention to produce harmful effect to human body.
Especially, particularly point out in one one of Pharmacopoeia of the People's Republic of China version in 2005: Radix Codonopsis should not be with black false hellebore with using.Yet find through after the inventor great many of experiments, add simultaneously Radix Codonopsis and black false hellebore not only can increase repelling effect in mosquito-repellent incense, and can't produce harmful effect to human body.
Experimental results show that, the present invention has certain inhibition, killing action to multiple germs such as gold look staphylococcus, shigella dysenteriae, tubercle bacillus, Pseudomonas aeruginosa, bacillus anthracis, hepatitis bacillus, particularly the virus and bacteria for the epidemic infection disease has very strong insect killing effect, and mosquito is had the stronger effect of killing.
Embodiment
Embodiment 1:
Take: 70 kilograms of tarragons, 25 kilograms of oriental wormwoods, 3 kilograms of lilac daphnes, 3 kilograms of asafoetides, 15 kilograms of elm barks, 3 kilograms, santal, 35 kilograms of camphorwoods, 3 kilograms of peppermints, 4 kilograms of agalloch eaglewood, 3 kilograms of west safflowers, 0.5 kilogram, Moschus.
Above-mentioned each component is dried and crushed into respectively 80-120 purpose powder, adds water and fully be mixed into mud, mud is put into joss sticks manufacturing machine extrusion molding post-drying, can make Foliu artemisiae argyi type mosquito-repellent incense of the present invention.
Embodiment 2:
Take: 80 kilograms of tarragons, 20 kilograms of oriental wormwoods, 6 kilograms of lilac daphnes, 1 kilogram of asafoetide, 25 kilograms of elm barks, 1 kilogram, santal, 40 kilograms of camphorwoods, 1 kilogram of peppermint, 6 kilograms of agalloch eaglewood, 1 kilogram of west safflower, 1.5 kilograms, Moschus.
Above-mentioned each component is dried and crushed into respectively 80-120 purpose powder, adds water and fully be mixed into mud, mud is put into joss sticks manufacturing machine extrusion molding post-drying, can make Foliu artemisiae argyi type mosquito-repellent incense of the present invention.
Embodiment 3:
Take: 75 kilograms of tarragons, 23 kilograms of oriental wormwoods, 5 kilograms of lilac daphnes, 2 kilograms of asafoetides, 20 kilograms of elm barks, 2 kilograms, santal, 38 kilograms of camphorwoods, 2 kilograms of peppermints, 5 kilograms of agalloch eaglewood, 2 kilograms of west safflowers, 1 kilogram, Moschus, 3 kilograms of black false hellebores, 1 kilogram of Radix Codonopsis.
Above-mentioned each component is dried and crushed into respectively 80-120 purpose powder, adds water and fully be mixed into mud, mud is put into joss sticks manufacturing machine extrusion molding post-drying, can make Foliu artemisiae argyi type mosquito-repellent incense of the present invention.
Embodiment 4:
Take: 75 kilograms of tarragons, 23 kilograms of oriental wormwoods, 5 kilograms of lilac daphnes, 2 kilograms of asafoetides, 20 kilograms of elm barks, 2 kilograms, santal, 38 kilograms of camphorwoods, 2 kilograms of peppermints, 5 kilograms of agalloch eaglewood, 2 kilograms of west safflowers, 1 kilogram, Moschus.
Above-mentioned each component is dried and crushed into respectively 80-120 purpose powder, adds water and fully be mixed into mud, mud is put into joss sticks manufacturing machine extrusion molding post-drying, can make Foliu artemisiae argyi type mosquito-repellent incense of the present invention.
Test case 1: indoor harmacological effect
Adopt mosquito-repellent incense indoor harmacological effect assay method and the evaluation criterion of GB/T 13917.4-2009 regulation, test.Concrete grammar is as follows:
1, for the examination material
Adopt the sensitive strain standard examination worm of laboratory rearing.
Culex pipiens pallens (Culex pipiens pallens), the 3rd day~the 5th day female insect for sucking blood after sprouting wings.
2, instrument and equipment
Cylinder unit
Water white transparency cylinder frame is on support, and cylinder respectively has a water white transparency garden plate up and down.There is a circular hole in upper plectane central authorities, clog with plug; There is a circular hole in lower plectane central authorities, clog with plug, and plug is added mosquito coil frame, for placing tested mosquito-repellent incense; Reveal with protection from fumes with the rubber washer pad respectively cylinder and upper and lower plectane joint.
Mosquito sucking tube, stopwatch, counter
3, test method
Experiment condition: temperature: (26 ± 1) ℃; Relative moisture: 60% ± 10%
4, experimental procedure
Adopt cylinder unit.Draw 30 of examination mosquitos, put into the jam-pack plug from the central circular hole place of cylinder below plectane.After trying worm recovery normal activity, get at random one section of mosquito-repellent incense to be measured, horizontal on mosquito coil frame; after lighting 5min in advance elsewhere, move to and smoke cigarette 1min in cylinder, immediately mosquito-repellent incense is removed; plug, and timing beyond the Great Wall records down and out examination borer population at regular intervals.Be limited to 20min during observation.Test should be established three times and above repetition, and repeated test should be coiled mosquito-repellent incense in difference with mosquito-repellent incense and taked at random.After each off-test, answer the washing test device.
5, calculate
The retest data are pressed linear weighted function Return Law calculating K T50 value and virulence regression equation.
6, evaluation index
Carry out evaluating drug effect according to KT50.
The drug effect result is divided into A, B two-stage, does not reach B grade standard person and belongs to substandard product.
A level: KT50≤4.0 minute; B level: KT50≤8.0 minute.
Table 1: mosquito-repellent incense indoor harmacological effect table
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
The KT50 value 2 minutes 11 seconds 2 minutes 23 seconds 1 minute 50 seconds 2 minutes 20 seconds
Test case 2: toxotest
With reference to health ministry " management of occupational acute chemicals Poisoning disease in the blood system diagnostic criteria " and " technological guidance's principle of Chinese medicine, the research of natural drug immunotoxicity " standard, formulate test case of the present invention.
1. the mosquito-repellent incense of experiment material: embodiment 3
2. experiment kind: two young age small white mouse.
3. experimental technique:
(1) experiment condition: laboratory temperature (27 ± 2) ℃
(2) experimental provision: in the laboratory of two 25 square metres of uniform temps, each places fine and closely woven ventilative netted the shrouding of 80 * 80 * 80cm of a big or small same size.
(3) experimental procedure: with two young age small white mouse separately respectively be put in netted the shrouding in two laboratories, and be divided into control group and smoke mosquito-repellent incense group of the present invention, give respectively not smoke mosquito-repellent incense of the present invention and smoke mosquito-repellent incense of the present invention, measure children's small white mouse body weight in age, the recovery situation after observing the biochemical index of hematology, histopathology changes and stopping smoking mosquito-repellent incense of the present invention etc.To be arranged on when placing mosquito-repellent incense of the present invention netted shroud interior the end of from 30 centimeters.Dosage: shroud interior morning of a late dish mosquito-repellent incense, keep 24 hours mosquito-repellent incense Chang Ran.Time: used continuously one month, and observed control group and smoke the small white mouse in young age of mosquito-repellent incense group of the present invention, use for a long time mosquito-repellent incense of the present invention to toxicity and the side effect of children small white mouse in age.Cleaning: shroud interior two days cleanings once.
Table 2: children's small white mouse mosquito-repellent incense toxicity test statistical form in age
Figure BSA00000591936700061
Above children's small white mouse mosquito-repellent incense toxicity test statistical form in age is taken from the sampling combination table that obvious situation record was arranged in five days that in month, add up every day, tests altogether 30 days, adds a week of stopping using and observing, totally 37 days.After two young age small white mouse blood tests, every biochemical indicator is normally, shows that mosquito-repellent incense of the present invention has no side effect to children small white mouse in age, only has to surpass when indoor mosquito-repellent incense smog was too dense in 24 hours, need window and take a breath 10-15 minute, draw blood front 8 hours not to two children small white mouses in age feeds.
Result: after each main organs heart, liver, spleen, lung, kidney, suprarenal gland, brain etc. were dissected, naked eyes are no abnormal variation all.Smoke mosquito-repellent incense group organ coefficient of the present invention and do not smoke mosquito-repellent incense group of the present invention relatively there are no significant difference, the organs and tissues pathological examination has no the significantly pathological change such as atrophy, sex change, necrosis, and does not smoke relatively there was no significant difference (P>0.03) of mosquito-repellent incense group of the present invention.
Conclusion: use for a long time mosquito-repellent incense of the present invention to children age small white mouse without any toxicity.
Test case 3: acute oral toxicity test
The mosquito-repellent incense of experiment material: embodiment 3.The rear 5 minutes activities in rats of contaminating increase, and continue about 2 minutes, and activity transfers to normally, and diet is normal, and the observation period, LD50 belonged to actual nontoxic greater than 5000 mg/kgs without death.
Test case 4: acute inhalation toxicity test
The mosquito-repellent incense of experiment material: embodiment 3.Rat diet activity no abnormality seen after contamination, the observation period, LD50 belonged to actual nontoxic greater than 10 gram/cubic meters without death.
Test case 5: skin patch test
The mosquito-repellent incense of experiment material: embodiment 3.It is 0 that experimental group erythema and oedema form the scoring sum, illustrates skin is had no stimulation.
Test case 6: eye irritant test
It is 0 that the experimental group acute ocular stimulates the integration number, illustrates mucous membrane is had no stimulation.
Test case 7: treatment tinea pedis test
Especially, the inventor is surprised to find that the residue after mosquito incense burning of the present invention, and namely the mosquito-repellent incense ash also has the effect for the treatment of tinea pedis.20 routine tinea pedis patients are tested, adopt the disclosed method of testing of Chinese invention patent Granted publication CN100448443C, residue after the mosquito incense burning of the embodiment of the present invention 3 is added in rice vinegar, the amount of rice vinegar used is 10 times of residue weight after mosquito incense burning, mix, be coated on the skin of suffering from tinea pedis, sooner or later each medication once, 14 days is a course for the treatment of.Treated effect reaches 90%.

Claims (2)

1. a Foliu artemisiae argyi type mosquito-repellent incense, is characterized in that, is comprised of by weight following component: tarragon 70-80 part, oriental wormwood 20-25 part, lilac daphne 3-6 part, asafoetide 1-3 part, elm bark 15-25 part, santal 1-3 part, camphorwood 35-40 part, peppermint 1-3 part, agalloch eaglewood 4-6 part, west safflower 1-3 part, Moschus 0.5-1.5 part.
2. a Foliu artemisiae argyi type mosquito-repellent incense, is characterized in that, is comprised of by weight following component: tarragon 70-80 part, oriental wormwood 20-25 part, lilac daphne 3-6 part, asafoetide 1-3 part, elm bark 15-25 part, santal 1-3 part, camphorwood 35-40 part, peppermint 1-3 part, agalloch eaglewood 4-6 part, west safflower 1-3 part, Moschus 0.5-1.5 part, black false hellebore 2-4 part, Radix Codonopsis 0.5-1.5 part.
CN2011103102747A 2011-09-28 2011-09-28 Mugwort leaf mosquito incense Expired - Fee Related CN102326590B (en)

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