CN102293781A - Low-corrosive cleaning solution - Google Patents
Low-corrosive cleaning solution Download PDFInfo
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- CN102293781A CN102293781A CN201110259466XA CN201110259466A CN102293781A CN 102293781 A CN102293781 A CN 102293781A CN 201110259466X A CN201110259466X A CN 201110259466XA CN 201110259466 A CN201110259466 A CN 201110259466A CN 102293781 A CN102293781 A CN 102293781A
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- iodine
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- cleaning solution
- potassium iodide
- cleanout fluid
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Abstract
The invention relates to a medical preparation containing an inorganically effective component, iodine and a compound thereof, and especially relates to a low-corrosive cleaning solution, the cleaning solution comprises the following components by mass percentage: 0.1%-0.5% of iodine, 10%-20% of polyvinylpyrrolidone, 0.03%-0.3% of potassium iodide, 0.02%-0.2% of castor-oil plant acid and the balance of water. The pigmentation can not be caused when the cleaning solution contacts the skin, because the iodine tincture has strong irritation, after disinfecting by the iodine tincture, the process of iodine removal by alcohol requires twice during the clinic application, the cleaning solution of the invention dose not require the process of iodine removel.
Description
Technical field
The present invention relates to contain medicinal preparation, iodine and the chemical compound thereof of inorganic effective ingredient, refer to a kind of low-corrosiveness cleanout fluid especially.
Background technology
Most popular cleanout fluid is to contain the iodine cleanout fluid on the China market at present, with iodine tincture is many, as everyone knows, iodine belongs to halogen family, it has dual character, resemble a double-edged sword: it has the total strong oxidation characteristic of halogen on the one hand, and bacterial virus is had the powerful ability of killing, and belongs to the high-effective disinfecting element.It has intensive corrosivity and zest again on the other hand, can only be used for skin degerming, can not be used for regard to film and wound disinfection, if handle badly, will damage human body or animal body.
Iodine tincture is dissolved in alcoholic solution and is made by iodine, potassium iodide.Iodine is a kind of solid, and potassium iodide helps the dissolving of iodine in ethanol.The concentration of commercially available iodine tincture is 2%.Iodine tincture has the powerful pathogen effect of killing, and it can make the protein generation degeneration of pathogen.Iodine tincture can kill bacteria, fungus, virus, ameba etc., can be used to treat many bacillary, fungoids, dermatosis such as viral.What need reminds people is, iodine tincture has certain zest, but the chafe pigment cell secretes pigment, with staying temporary pigmentation spots on the skin of back.Wound surface can not directly be used for sterilizing, and easily burns and causes wound surface deepening.And povidone iodine is far better, can be used for the cleaning and sterilizing of wound surface.But not only 3% iodine tincture can burned skin, 1.5% the iodine tincture that we adopt also can cause superficial second degree burn, along with the increase that contains iodine concentration, pessimal stimulation to skin also strengthens thereupon, iodine tincture can produce coup injury-burn to skin, gently then decortication, heavy then blister and skin injury postoperative infection.
As application number: 95111245.7 applyings date: 1995-02-17, name is called the patent of invention of " chelated iodine liquid disinfectant ", its technical scheme is: a kind of chelated iodine liquid disinfectant is provided, the iodine that contains 0.05～4 (percentage by weight), the Polyethylene Glycol of～40 1.0 (percentage by weights), the fatty alcohol-polyoxyethylene ether of～4 0.1 (percentage by weights), deionized water.Have decontamination washing, the multiple function of disinfection simultaneously, efficient height, good stability, production technology is simple, and raw material is easy to get, and cost is low, easy to use, applied range can be widely used in various body surface environment disinfecteds such as family, hospital, hotel, dining room, public place, nurseries and kindergartens mechanism.But its content of iodine has still surpassed the dangerous critical line that human body bears.
So all the time, people have no idea an optimal state is handled in the dual character of iodine, that is: fungicidal effectiveness and safety all reach maximization.And the available iodine content of general iodine tincture is all more than 2%, and this consumption for iodine resource more and more in short supply is very inappropriate.
Summary of the invention
The object of the present invention is to provide that a kind of fungicidal effectiveness is strong, safe, good stability, and corrosivity and zest be low, can be used for skin, with regard to film and wound disinfection and the low cleanout fluid of available iodine content, the technical solution adopted for the present invention to solve the technical problems is:
A kind of low-corrosiveness cleanout fluid is characterized in that: the mass percent component is as follows:
Iodine 0.1%-0.5%;
Polyethylene adjoins pyrrolidone 10%-20%;
Potassium iodide: 0.03%-0.3%;
Ricinoleic acid 0.02%-0.2%;
All the other are pure water.
Described a kind of low-corrosiveness cleanout fluid, it is characterized in that: the mass percent component is as follows:
Iodine 0.3%;
Polyethylene adjoins pyrrolidone 15%;
Potassium iodide: 0.15%;
Ricinoleic acid 0.15%;
All the other are pure water.
The invention has the advantages that:
This component is removed the iodine molecule that does not possess bactericidal activity substantially to live and is effective sterilization factors, so both improved fungicidal effectiveness greatly, avoided the waste of I again, be that a kind of fungicidal effectiveness is strong, safe, good stability, and corrosivity and zest is low, can be used for skin, with regard to film and wound disinfection and the low low-corrosiveness cleanout fluid of available iodine content.The shortcoming of can also overcome general iodine low-corrosiveness cleanout fluid Huang, gluing, steeping.Its bactericidal action wide spectrum, but kill vegetative forms of bacteria, spore, fungus and part virus.This cleanout fluid toxicity is low, non-corrosiveness; There is not xanthochromia yet, can pollution clothes when spreading upon on one's body, and this cleanout fluid contact skin can not cause pigmentation, but there is such shortcoming in iodine tincture.Because the zest of iodine tincture is strong, during clinical practice, need behind the iodine disinfection to take off iodine twice with ethanol, and this cleanout fluid does not need to take off iodine.Iodine tincture has volatility to a certain degree, influence solution concentration easily, and this cleanout fluid can not volatilize generally, and stability better.
The specific embodiment
A kind of low-corrosiveness cleanout fluid is characterized in that: the mass percent component is as follows:
Iodine 0.1%-0.5%;
Polyethylene adjoins pyrrolidone 10%-20%;
Potassium iodide: 0.03%-0.3%;
Ricinoleic acid 0.02%-0.2%;
All the other are pure water.
Described a kind of low-corrosiveness cleanout fluid, it is characterized in that: the mass percent component is as follows:
Iodine 0.3%;
Polyethylene adjoins pyrrolidone 15%;
Potassium iodide: 0.15%;
Ricinoleic acid 0.15%;
All the other are pure water.
Polyethylene adjoins pyrrolidone terpineol; Terpilenol; Alpha-Terpineol.CAS?No.：?10482-56-1。
Molecular formula (Formula): C10H18O, molecular weight (Molecular Weight): 154.25.
Physico-chemical property (Physical Properties): the transparent crystallization of colourless thick liquid or low melting point.0.9337 ℃ of relative density.40 ℃ of solidification points.220.85 ℃ of boiling points.Refractive index 1.4831.Flammable.The general industry product are three kinds of mixture of isomers.α-polyethylene adjoins pyrrolidone left-handed, dextrorotation, three kinds of optical isomers of racemization.(+)-α-body is present in Oleum Terebinthinae, Cardamom oil, oleum Citri sinensis, the Semen Myristicae wet goods quintessence oil; (-)-α-body is present in pinke needle oil, Bay leaves oil, Fructus Citri Limoniae oil, the limette wet goods quintessence oil; (±)-α-body is present in Oleum Pelargonii Graveolentis, cajaput wet goods quintessence oil; γ-body once had discovery in the himalayan cypress leaf oil.It is colourless glop that polyethylene adjoins pyrrolidone.214～224 ℃ of boiling ranges (101.3kPa).Water insoluble, be dissolved in organic solvents such as ethanol.Tool is like the delicate fragrance of tobira, sweet Syringa oblata Lindl., Herba Convallariae breath.Be dissolved in ethanol, be slightly soluble in water and glycerol.1 part of polyethylene adjoins in the alcoholic solution that pyrrolidone can be dissolved in 2 parts of (volumes) 70%.Preparation: with the Oleum Terebinthinae is raw material, adds a small amount of average emulsifying agent that adds as at sulphuric acid, carries out hydration reaction under the room temperature, makes after the main component pinene generates terpini hydras in the Oleum Terebinthinae, through dewatering to such an extent that thick polyethylene adjoins pyrrolidone, makes through fractional distillation.
White cube crystallization of potassium iodide character or powder.Little in humid air have a hygroscopicity, puts for a long time and separate out free-iodine and yellowing, and can form the micro iodine hydrochlorate.Light and moist energy accelerated decomposition.1g is dissolved in 0.7ml water, 0.5ml boiling water, 22ml ethanol, 8ml boil ethanol, 51ml dehydrated alcohol, 8ml methanol, 7.5ml acetone, 2ml glycerol, about 2.5ml ethylene glycol.Its aqueous solution is neutrality or alkalescence, can dissolve iodine.Its aqueous solution also can oxidation and the gradual change yellow can add small amount of alkali and prevent.Relative density 3.12.680 ℃ of fusing points.1420 ℃ of boiling points.ALD (rat, vein) 285mg/kg.Be used for making organic compound and chemical reagent etc.It is exactly to add potassium iodide or potassium iodate (in 20,000/ ratio) in common Sal (pure sodium chloride) that the what is called that we often eat adds the iodine edible salt.Potassium iodide has some special purposes in the department of dermatologry field.Its mechanism of action partly is owing to the dissolving and the Digestion that have strengthened slough.Potassium iodide also has antifungal activity.Clinically treat sporotrichosis, chromoblastomycosis, persistent erythema nodosum and nodular vasculitis etc. with it.Also will note its side effect when using potassium iodide, it can cause pustule, vesicle, erythema, eczema, urticaria etc., and acne is increased the weight of, and also can cause digestive tract reaction and mucosal symptoms certainly.Pharmaceutically be used to prevent and treat endemic goiter, promoting the absorption of vitreum muddiness and eliminate the phlegm.Potassium iodide is the raw material of preparation iodide and dyestuff.Cosolvent as photosensitive emulsifying agent, food additive, iodine and some insoluble metal iodide.Also can be used as analytical reagent, chromatographic analysis and point analyzes bitterly.Potassium iodide is stabilizing agent and cosolvent, and the potassium iodide of feed grade also can be cooked the supplement as iodine in the feedstuff processing.
Ricinoleic acid is used to prepare surfactant, plasticizer, lube oil additive, also is used to prepare decanedioic acid, enanthic acid etc.
Embodiment 1
A kind of low-corrosiveness cleanout fluid, the mass percent component is as follows:
Iodine 0.1%; Polyethylene adjoins pyrrolidone 20%; Potassium iodide 0.3%; Ricinoleic acid 0.2%; All the other are pure water.
Embodiment 2
A kind of low-corrosiveness cleanout fluid, the mass percent component is as follows:
Iodine 0.5%; Polyethylene adjoins pyrrolidone 10%; Potassium iodide 0.03%; Ricinoleic acid 0.02%; All the other are pure water.
Embodiment 3
A kind of low-corrosiveness cleanout fluid, the mass percent component is as follows:
Iodine 0.3%; Polyethylene adjoins pyrrolidone 15%; Potassium iodide: 0.15%; Ricinoleic acid 0.15%; All the other are pure water.
Claims (2)
1. low-corrosiveness cleanout fluid, it is characterized in that: the mass percent component is as follows:
Iodine 0.1%-0.5%; Polyethylene adjoins pyrrolidone 10%-20%; Potassium iodide 0.03%-0.3%;
Ricinoleic acid 0.02%-0.2%; All the other are pure water.
2. described a kind of low-corrosiveness cleanout fluid according to claim 1, it is characterized in that: the mass percent component is as follows:
Iodine 0.3%; Polyethylene adjoins pyrrolidone 15%; Potassium iodide 0.15%; Ricinoleic acid 0.15%; All the other are pure water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110259466XA CN102293781A (en) | 2011-09-05 | 2011-09-05 | Low-corrosive cleaning solution |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110259466XA CN102293781A (en) | 2011-09-05 | 2011-09-05 | Low-corrosive cleaning solution |
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| CN102293781A true CN102293781A (en) | 2011-12-28 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104430569A (en) * | 2014-11-25 | 2015-03-25 | 邓建军 | Disinfectant for cleaning CT equipment and preparation method thereof |
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2011
- 2011-09-05 CN CN201110259466XA patent/CN102293781A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104430569A (en) * | 2014-11-25 | 2015-03-25 | 邓建军 | Disinfectant for cleaning CT equipment and preparation method thereof |
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Application publication date: 20111228 |