CN102688257A - Liquid molecular iodine disinfectant, preparation method and used container - Google Patents
Liquid molecular iodine disinfectant, preparation method and used container Download PDFInfo
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- CN102688257A CN102688257A CN2012101863822A CN201210186382A CN102688257A CN 102688257 A CN102688257 A CN 102688257A CN 2012101863822 A CN2012101863822 A CN 2012101863822A CN 201210186382 A CN201210186382 A CN 201210186382A CN 102688257 A CN102688257 A CN 102688257A
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Abstract
The invention discloses a liquid molecular iodine disinfectant, which comprises an iodide, an oxidant and an acidity pH regulator, wherein the oxidant can be used for oxidizing the iodide to generate iodine molecules, and the acidity pH regulator is used for regulating a mixture of the iodide and the oxidant to be acid. The disinfectant consists of a composition of a preparation 1 containing the iodide and the oxidant and a preparation 2 containing the acidity pH regulator; the preparation 1 and the preparation 2 are in a liquid state respectively; and the pH value of the preparation I is greater than 6.5. The liquid molecular iodine disinfectant disclosed by the invention not only is high in stability, can be stored for a long time, is light in irritation to skins, rapid in penetration and volatilization, light in coloring and obvious in sterilizing effect and does not need to be de-iodinated but also is safe and convenient in use and carrying. The liquid molecular iodine disinfectant disclosed by the invention has a broad-spectrum sterilizing effect and is light in irritation to skin mucosae and can be used for various skin diseases caused by bacteria, fungi and viruses.
Description
Technical field
The present invention relates to medical technical field, relate in particular to a kind of liquid molecular iodine disinfectant preparation that is used for skin degerming.
Background technology
Iodine is that the sterile products that everybody uses always, particularly iodine tincture preparations such as (iodine tinctures) is everybody very familiar sterilizing product, is widely used in hospital and the daily life.Iodine is one of broad-spectrum elimination agent, can kill microorganisms such as various antibacterials, fungus, virus in 100% ground, and not produce drug resistance.Also do not find in the world at present the drug-fast microorganism of iodine.
But the Operand that uses at present exists great defective: like iodine tincture (iodine tincture) etc. the anaphylaxis of intensive dyeability and adjuvant and low excessively activity are arranged.Causing the low excessively main cause of present Operand activity is that the content of free molecular iodine in whole Operand is too low, and As time goes on its content is also continuing reduction, and the content of the iodide ion a little less than the other forms of bactericidal action is very high.So not only influenced the bactericidal effect of iodine, also human body skin has been produced the strong impulse effect, and can produce intensive xanthochromia property, influenced attractive in appearance at site of action.And because iodine has volatility, can descend much if iodine is placed the back active constituent content for a long time with the form of molecule, influence final use bactericidal effect.In order to guarantee the Disinfection Effect of iodine tincture (iodine tincture), generally use higher iodine concentration, the stimulation to skin when causing using like this is bigger.These defectives have greatly limited the range of application of iodine.
Summary of the invention
First technical problem to be solved by this invention is: the deficiency to prior art exists, and provide a kind of bactericidal effect good, little to skin irritation, good stability, can store for a long time and do not reduce the liquid molecular iodine disinfectant preparation of bactericidal effect.
Second technical problem to be solved by this invention is: provide a kind of bactericidal effect good, and little to skin irritation, good stability, can store for a long time and do not reduce the method for preparing of the liquid molecular iodine disinfectant preparation of bactericidal effect.
The 3rd technical problem to be solved by this invention is: a kind of container that holds liquid disinfectant preparation that is applicable to is provided, uses easy to carry.
For solving above-mentioned first technical problem, technical scheme of the present invention is:
A kind of liquid molecular iodine disinfectant preparation; Comprise iodide; Can make said iodide oxidation produce the oxidant of iodine molecule and the mixture of said iodide and oxidant is adjusted to tart acidic ph modifier, said disinfectant preparation is combined by preparation that comprises said iodide and oxidant 1 and the preparation 2 that comprises said acidic ph modifier; Said preparation 1 is liquid form with preparation 2, and the pH value of said preparation 1 is more than 6.5.
As a kind of optimized technical scheme, said preparation is a solution, and said solution is made up of solution that comprises said iodide and oxidant 1 and the solution 2 that comprises said acidic ph modifier.The component that comprises following percetage by weight in the said solution 1:
The component that comprises following percetage by weight in the said solution 2:
Wetting agent, antiseptic, penetrating agent in solution 1 and the solution 2 can select to add wherein one or more as required.
As another kind of optimized technical scheme; Said preparation is a gel; Said gel is made up of gel that comprises said iodide and oxidant 1 and the gel 2 that comprises said acidic ph modifier, comprises the component of following percetage by weight in the said gel 1:
The component that comprises following percetage by weight in the said gel 2:
Wetting agent in gel 1 and the gel 2, antiseptic, penetrating agent can select to add wherein one or more as required.
Wherein, said iodide be for producing the anionic iodine compound of iodine in solution, preferred sodium iodide, potassium iodide, magnesium iodide, calcium iodide and zinc iodide, or in other iodized salts one or more.
Said oxidant is the material that can said iodide oxidation be produced iodine molecule, and said oxide is at least a in iodate, the periodate.Preferably: one or more in sodium iodate, potassium iodate, Magnesium iodate., Copper diiodate(Cu(IO3)2), calcium iodate, zinc iodate, Potassium metaperiodate., the sodium metaperiodate.This compounds has oxidisability, particularly in sour environment, can the iodide oxidation be produced elemental iodine.
Said alkaline pH regulator is one or more in sodium carbonate, potassium carbonate, sodium bicarbonate, the potassium bicarbonate.More than the pH regulator to 6.5 of said alkaline pH regulator with the pharmaceutical composition in solution 1, the gel 1.
Said acidic ph modifier is one or more in phosphoric acid, citric acid, tartaric acid, salicylic acid, the malic acid.Said acidic ph modifier with below the gel 2 mixed pH regulator to 6.0, preferably is adjusted to solution 1 and solution 2, gel 1 below 4.5.
Said wetting agent is one or both in the skin moisturizers such as glycerin, propylene glycol.Said antiseptic is one or more in methyl hydroxybenzoate, ethyl hydroxybenzoate and the propyl hydroxybenzoate.Said penetrating agent is one or both in menthol, the azone.
Said polymer-based material is one or more in methylcellulose, ethyl cellulose, sodium carboxymethyl cellulose, hypromellose, hyetellose, hyprolose, guar gum, the xanthan gum.
For solving above-mentioned second technical problem, technical scheme of the present invention is:
Prepare the method for liquid molecular iodine disinfectant preparation, may further comprise the steps:
A, according to the percentage by weight of each component in the solution; Be dissolved in iodide and oxidant in the water at normal temperatures; Selectivity adds one or more in alkaline pH regulator, dehydrated alcohol, wetting agent, penetrating agent and the antiseptic, promptly gets solution 1 after mixed dissolution is complete; Acidic ph modifier is dissolved in the water at normal temperatures, and selectivity adds one or more in dehydrated alcohol, wetting agent, penetrating agent and the antiseptic then, promptly gets solution 2 after mixed dissolution is complete.
B, according to the percentage by weight of each component in the gel; Earlier iodide and oxidant are dissolved with low amounts of water, polymer-based material is used the low amounts of water swelling, add dissolved iodide and oxidant then; Add in alkaline pH regulator, dehydrated alcohol, wetting agent, penetrating agent and the antiseptic one or more more as required; Add the water of surplus, stir, promptly get gel 1; Polymer-based material is added water-soluble expanding, add in acidic ph modifier, dehydrated alcohol, wetting agent, penetrating agent and the antiseptic one or more as required, add the water of surplus, stir, promptly get gel 2.
For solving above-mentioned the 3rd technical problem, technical scheme of the present invention is:
The used packing container of a kind of liquid molecular iodine disinfectant preparation, said container is provided with two separate chambers, is used for holding said preparation 1 and preparation 2.
Said two separate chambers have a common press device, and said press device is respectively equipped with the suction pipe that is communicated with two separate chambers, make simultaneously preparation 1 and preparation 2 extruding to be come out when pushing said press device;
Perhaps, said two separate chambers are respectively equipped with independently press device, said two independently press device be respectively equipped with the suction pipe that is communicated with two separate chambers.
Owing to adopted technique scheme, the invention has the beneficial effects as follows:
Iodine disinfectant preparation of the present invention comprises iodide; Can make the iodide oxidation produce the oxidant of iodine molecule; Be adjusted to tart acidic ph modifier with the mixture with iodide and oxidant, and disinfectant preparation combines by preparation that comprises iodide and oxidant of liquid state 1 and the preparation 2 that comprises acidic ph modifier, the pH value of said preparation 1 is more than 6.5; Therefore liquid formulation before use; Iodine wherein can be present in the preparation with its stable form, therefore good stability is arranged, and can store for a long time.And the prolongation that effective ingredient molecular iodine content can be not in time when preparation used and descending, so the content of iodine in the preparation does not need too high.When the present invention uses, after preparation 1 mixes with preparation 2, in sour environment, can the moment reaction produce required free molecule iodine; The free molecule iodine that produces can reach quick sterilization, bacteriostatic effect, because the molecular iodine that produces in the solution is the molecular iodine that produces moment, it is effective extremely therefore to disappear; Do not need higher concentration just can reach bactericidal effect, little to the zest of skin, infiltration rapidly; Volatilization is fast, and is painted shallow, need not to take off iodine.
Dosage form of the present invention comprises solution and gel, and gel can form thin film at skin surface when using, and is attached on the skin, can prolong the disinfection time, has the long-acting bactericidal effect.And the molecular iodine that is absorbed by human body skin has played bactericidal action; And do not stayed in the gel film by the molecular iodine of skin absorbs; Can split away off; So just can not produce xanthochromia property, skin irritation is alleviated greatly, therefore can be implemented in the application of the skin at sense organ sensitive part such as positions such as face position, hand position skin.The present invention has broad-spectrum bactericidal action, and is low to Mucocutaneous zest, can be used for the various dermatosiss that caused by antibacterial, fungus, virus.
The present invention adopts special container to hold; Container is provided with two separate chambers, is used for holding preparation 1 and preparation 2, has a common press device; Perhaps two separate chambers are respectively equipped with independently press device; Can squeeze out two kinds of preparations simultaneously and directly mix the back and use, the preparation 1 that also can concentration as required squeezes out different volumes mixes the back use with preparation 2, portably use convenience.
The specific embodiment
Below in conjunction with concrete embodiment, further set forth the present invention.Should be understood that these embodiment only to be used to the present invention is described and be not used in the restriction scope of the present invention.Should be understood that in addition those skilled in the art can do various changes or modification to the present invention after the content of having read the present invention's instruction, these equivalent form of values fall within the application's appended claims institute restricted portion equally.
Embodiment 1
Sodium iodide 1g and Potassium metaperiodate. 0.3g are dissolved in the water at normal temperatures, add alkaline pH regulator potassium carbonate 0.1g, dehydrated alcohol 20g, propylene glycol 5g, menthol 0.1g, methyl hydroxybenzoate 0.1g, supply water 73.4g, promptly get solution 1 after mixed dissolution is complete.The pH of solution 1 is more than 6.5.Acidic ph modifier phosphoric acid 3.5g is dissolved in the 71.3g water at normal temperatures, adds dehydrated alcohol 20g, propylene glycol 5g, menthol 0.1g, methyl hydroxybenzoate 0.1g, promptly get solution 2 after mixed dissolution is complete.
During use, be 1:1:10 mixed dissolution (i.e. 1 gram solution 1 and 1 restrain solution 2 be dissolved in 10 and restrain in the water), can be made into the disinfectant antibacterial that carries out disinfection in the ratio of solution 1, solution 2 and water.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 2
Sodium iodide 8g and sodium iodate 2g are dissolved in the water at normal temperatures, add sodium bicarbonate 0.2g, dehydrated alcohol 25g, supply water 64.8g, promptly get solution 1 after mixed dissolution is complete.The pH of solution 1 is more than 6.5.Tartaric acid 20g is dissolved in the 55g water at normal temperatures, promptly gets solution 2 after adding dehydrated alcohol 25g mixed dissolution is complete.
During use, be 1:1:100 mixed dissolution (i.e. 1 gram solution 1 and 1 restrain solution 2 be dissolved in 100 and restrain in the water), can be made into the disinfectant antibacterial that carries out disinfection in the ratio of solution 1, solution 2 and water.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 3
Potassium iodide 20g and potassium iodate 5g are dissolved in the water at normal temperatures, add sodium carbonate 2g, supply water 73g, promptly get solution 1 after mixed dissolution is complete.The pH of solution 1 is more than 6.5.Phosphoric acid 20g is dissolved in the 80g water at normal temperatures, promptly gets solution 2 after mixed dissolution is complete.
During use, be 1:1:100 mixed dissolution (i.e. 1 gram solution 1 and 1 restrain solution 2 be dissolved in 100 and restrain in the water), can be made into the disinfectant antibacterial that carries out disinfection in the ratio of solution 1, solution 2 and water.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 4
Potassium iodide 10g and potassium iodate 3g are dissolved in the water at normal temperatures, add sodium carbonate 1g, dehydrated alcohol 10g, azone 1g and propyl hydroxybenzoate 0.2g, supply water 74.8g, promptly get solution 1 after mixed dissolution is complete.The pH of solution 1 is more than 6.5.Salicylic acid 1g and malic acid 9g are dissolved in the water at normal temperatures, add dehydrated alcohol 25g, propylene glycol 2g, menthol 0.5g then, supply water 62.5g, promptly get solution 2 after mixed dissolution is complete.
During use, be 1:1:50 mixed dissolution (i.e. 1 gram solution 1 and 1 restrain solution 2 be dissolved in 50 and restrain in the water), can be made into the disinfectant antibacterial that carries out disinfection in the ratio of solution 1, solution 2 and water.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 5
Earlier potassium iodide 0.1g and Potassium metaperiodate. 0.1g are dissolved with low amounts of water; With sodium carboxymethyl cellulose 2g with 10g dehydrated alcohol swelling; Add dissolved potassium iodide and Potassium metaperiodate. then, add sodium carbonate 0.5g, glycerin 10g and ethyl hydroxybenzoate 0.05g again, supply water 77.25g; Stir, promptly get gel 1; The pH of gel 1 is more than 6.5.Methylcellulose 2g is added 10g dehydrated alcohol swelling, add citric acid 2g, glycerin 10g, add the water of 76g, stir, promptly get gel 2.
During use, press gel 1 and gel 2 and be the mixed of 1:1 evenly (promptly 1 gram gel 1 and 1 restrains gel 2 mix homogeneously), can be made into the disinfectant antibacterial that carries out disinfection.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 6
Earlier sodium iodide and potassium iodide 6g and potassium iodate 2g are used water dissolution; With methylcellulose and ethyl cellulose 4g with dehydrated alcohol 30g swelling; Add dissolved sodium iodide, potassium iodide and potassium iodate then, add sodium carbonate 0.5g, menthol 1g and ethyl hydroxybenzoate 0.2g again, add the water of 56.3g; Stir, promptly get gel 1; The pH of gel 1 is more than 6.5.Hypromellose 4g is added 20g dehydrated alcohol swelling, add malic acid 1.5g, menthol 1g and methyl hydroxybenzoate 0.2g, add the water of 73.3g, stir, promptly get gel 2.
During use, press gel 1 and gel 2 and be the mixed of 1:1 evenly (promptly 1 gram gel 1 and 1 restrains gel 2 mix homogeneously), can be made into the disinfectant antibacterial that carries out disinfection.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 7
Earlier potassium iodide 5g and potassium iodate 2g are used the 58.9g water dissolution, sodium carboxymethyl cellulose 4g with 30g dehydrated alcohol swelling, is added dissolved potassium iodide and potassium iodate then, add sodium carbonate 0.1g again and stir, promptly get gel 1; The pH of gel 1 is more than 6.5.Methylcellulose 4g with 30g dehydrated alcohol swelling, is added the water of tartaric acid 0.5g and 65.5g, stir, promptly get gel 2.
During use, press gel 1 and gel 2 and be the mixed of 1:1 evenly (promptly 1 gram gel 1 and 1 restrains gel 2 mix homogeneously), can be made into the disinfectant antibacterial that carries out disinfection.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Embodiment 8
Earlier potassium iodide 1g and sodium iodate 0.5g are dissolved with low amounts of water; Xanthan gum 1g is used the low amounts of water swelling; Add dissolved potassium iodide and sodium iodate then, add sodium bicarbonate 0.2g, dehydrated alcohol 10g, azone 1g and propyl hydroxybenzoate 0.03g again, add the water of 86.27g; Stir, promptly get gel 1; The pH of gel 1 is more than 6.5.Xanthan gum 1g is added water-soluble expanding, add citric acid 1g, dehydrated alcohol 10g and water 88g, stir, promptly get gel 2.
During use, press gel 1 and gel 2 and be the mixed of 1:1 evenly (promptly 1 gram gel 1 and 1 restrains gel 2 mix homogeneously), can be made into the disinfectant antibacterial that carries out disinfection.
Through test, the iodine disinfectant of present embodiment, 5min be to oidiomycetic logarithm value＞5.00 of on average killing of white, and 5min on average kills logarithm value＞5.00 to staphylococcus aureus, and 5min is to colibacillary logarithm value＞5.00 of on average killing.
Claims (10)
1. liquid molecular iodine disinfectant preparation; Comprise iodide; Can make said iodide oxidation produce the oxidant of iodine molecule and the mixture of said iodide and oxidant is adjusted to tart acidic ph modifier, it is characterized in that: said disinfectant preparation is combined by preparation that comprises said iodide and oxidant 1 and the preparation 2 that comprises said acidic ph modifier; Said preparation 1 is liquid form with preparation 2, and the pH value of said preparation 1 is more than 6.5.
2. liquid molecular iodine disinfectant preparation as claimed in claim 1; It is characterized in that: said preparation is a solution; Said solution is made up of solution that comprises said iodide and oxidant 1 and the solution 2 that comprises said acidic ph modifier, comprises the component of following percetage by weight in the said solution 1:
The component that comprises following percetage by weight in the said solution 2:
3. liquid molecular iodine disinfectant preparation as claimed in claim 1; It is characterized in that: said preparation is a gel; Said gel is made up of gel that comprises said iodide and oxidant 1 and the gel 2 that comprises said acidic ph modifier, comprises the component of following percetage by weight in the said gel 1:
The component that comprises following percetage by weight in the said gel 2:
4. like claim 2 or 3 described liquid molecular iodine disinfectant preparations; It is characterized in that: said iodide are for can produce the anionic iodine compound of iodine in solution, said iodine compound is one or more in sodium iodide, potassium iodide, magnesium iodide, calcium iodide, manganese iodide, ammonium iodide and the zinc iodide.
5. like claim 2 or 3 described liquid molecular iodine disinfectant preparations, it is characterized in that: said oxidant be for producing said iodide oxidation the material of iodine molecule, and said oxide is at least a in iodate, the periodate.
6. like claim 2 or 3 described liquid molecular iodine disinfectant preparations, it is characterized in that: said alkaline pH regulator is one or more in sodium carbonate, potassium carbonate, sodium bicarbonate, the potassium bicarbonate; Said acidic ph modifier is one or more in phosphoric acid, citric acid, tartaric acid, salicylic acid, the malic acid.
7. like claim 2 or 3 described liquid molecular iodine disinfectant preparations, it is characterized in that: said wetting agent is one or both in glycerin, the propylene glycol; Said antiseptic is one or more in methyl hydroxybenzoate, ethyl hydroxybenzoate and the propyl hydroxybenzoate; Said penetrating agent is one or both in menthol, the azone.
8. like claim 2 or 3 described liquid molecular iodine disinfectant preparations, it is characterized in that: said polymer-based material is one or more in methylcellulose, ethyl cellulose, sodium carboxymethyl cellulose, hypromellose, hyetellose, hyprolose, guar gum, the xanthan gum.
9. preparation is characterized in that may further comprise the steps like the method for claim 2 or 3 described liquid molecular iodine disinfectant preparations:
A, according to the percentage by weight of each component in the solution, iodide and oxidant are dissolved in the water at normal temperatures, add alkaline pH regulator, dehydrated alcohol, wetting agent, penetrating agent and antiseptic, mixed dissolution promptly gets solution 1 after fully; Acidic ph modifier is dissolved in the water at normal temperatures, adds dehydrated alcohol, wetting agent, penetrating agent and antiseptic then, promptly get solution 2 after mixed dissolution is complete;
B, according to the percentage by weight of each component in the gel; Earlier iodide and oxidant are dissolved with low amounts of water, polymer-based material with low amounts of water or dehydrated alcohol swelling, is added dissolved iodide and oxidant then; Add alkaline pH regulator, wetting agent, penetrating agent and antiseptic again; Add the water of surplus, stir, promptly get gel 1; Polymer-based material is added water or dehydrated alcohol swelling, add the water of acidic ph modifier, wetting agent, penetrating agent, antiseptic and surplus, stir, promptly get gel 2.
10. used packing container of liquid molecular iodine disinfectant preparation, it is characterized in that: said container is provided with two separate chambers, is used for holding said preparation 1 and preparation 2;
Said two separate chambers have a common press device, and said press device is respectively equipped with the suction pipe that is communicated with two separate chambers, make simultaneously preparation 1 and preparation 2 extruding to be come out when pushing said press device;
Perhaps, said two separate chambers are respectively equipped with independently press device, said two independently press device be respectively equipped with the suction pipe that is communicated with two separate chambers.
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| CN2012101863822A CN102688257A (en) | 2012-06-07 | 2012-06-07 | Liquid molecular iodine disinfectant, preparation method and used container |
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| CN2012101863822A CN102688257A (en) | 2012-06-07 | 2012-06-07 | Liquid molecular iodine disinfectant, preparation method and used container |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111437288A (en) * | 2020-05-20 | 2020-07-24 | 山东沙多普生物科技有限公司 | Atomized molecular iodine disinfectant and application thereof |
| CN112704080A (en) * | 2020-12-30 | 2021-04-27 | 佛山市正典生物技术有限公司 | Iodine-containing disinfectant with stable component content and preparation method thereof |
| CN112806387A (en) * | 2020-12-31 | 2021-05-18 | 佛山市正典生物技术有限公司 | Preparation method of iodine-containing disinfectant with stable component content |
| US11297839B2 (en) | 2014-03-31 | 2022-04-12 | ioTech International, Incorporated | Stable compositions of uncomplexed iodine and methods of use |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1098252A (en) * | 1988-04-11 | 1995-02-08 | 埃培托普公司 | The solid germicidal pre-iodine composition of stable storing |
-
2012
- 2012-06-07 CN CN2012101863822A patent/CN102688257A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1098252A (en) * | 1988-04-11 | 1995-02-08 | 埃培托普公司 | The solid germicidal pre-iodine composition of stable storing |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11297839B2 (en) | 2014-03-31 | 2022-04-12 | ioTech International, Incorporated | Stable compositions of uncomplexed iodine and methods of use |
| US11653653B2 (en) | 2014-03-31 | 2023-05-23 | Iotech International, Inc. | Stable compositions of uncomplexed iodine and methods of use |
| CN111437288A (en) * | 2020-05-20 | 2020-07-24 | 山东沙多普生物科技有限公司 | Atomized molecular iodine disinfectant and application thereof |
| CN112704080A (en) * | 2020-12-30 | 2021-04-27 | 佛山市正典生物技术有限公司 | Iodine-containing disinfectant with stable component content and preparation method thereof |
| CN112704080B (en) * | 2020-12-30 | 2022-02-22 | 佛山市正典生物技术有限公司 | Iodine-containing disinfectant with stable component content and preparation method thereof |
| CN112806387A (en) * | 2020-12-31 | 2021-05-18 | 佛山市正典生物技术有限公司 | Preparation method of iodine-containing disinfectant with stable component content |
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Application publication date: 20120926 |