CN102281907B - 生物复合材料及其制造方法 - Google Patents

生物复合材料及其制造方法 Download PDF

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Publication number
CN102281907B
CN102281907B CN200980140288.XA CN200980140288A CN102281907B CN 102281907 B CN102281907 B CN 102281907B CN 200980140288 A CN200980140288 A CN 200980140288A CN 102281907 B CN102281907 B CN 102281907B
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fibril
biopolymer
directed
collagen
methods according
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Chinese (zh)
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CN102281907A (zh
Inventor
米哈伊尔·维托多维奇·帕克施托
大卫·哈伍德·麦克默特里
乔治·R·马丁
塔蒂阿娜·塞茨瓦
尤里·亚历山德罗维奇·波洛夫
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Fibralign Corp
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Fibralign Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Artificial Filaments (AREA)
CN200980140288.XA 2008-08-11 2009-08-11 生物复合材料及其制造方法 Active CN102281907B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13606608P 2008-08-11 2008-08-11
US61/136,066 2008-08-11
PCT/US2009/053486 WO2010019625A2 (en) 2008-08-11 2009-08-11 Biocomposites and methods of making the same

Publications (2)

Publication Number Publication Date
CN102281907A CN102281907A (zh) 2011-12-14
CN102281907B true CN102281907B (zh) 2014-06-25

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CN200980140288.XA Active CN102281907B (zh) 2008-08-11 2009-08-11 生物复合材料及其制造方法

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EP (1) EP2331155B1 (enExample)
JP (2) JP5939563B2 (enExample)
CN (1) CN102281907B (enExample)
AU (1) AU2009282095B2 (enExample)
BR (1) BRPI0912470B8 (enExample)
RU (1) RU2500432C2 (enExample)
WO (1) WO2010019625A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108379655A (zh) * 2018-05-22 2018-08-10 中山大学 具有三维取向结构的神经移植物及其制备方法和制作设备

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US8492332B2 (en) 2007-04-19 2013-07-23 Fibralign Corporation Oriented collagen-based materials, films and methods of making same
US10086079B2 (en) 2008-08-11 2018-10-02 Fibralign Corporation Biocomposites and methods of making the same
US8513382B2 (en) 2008-08-11 2013-08-20 Fibralign Corporation Biocomposites and methods of making the same
FR2960439B1 (fr) * 2010-05-31 2012-06-15 Univ Paris Curie Matrices fibrillaires denses de collagene pour la reparation tissulaire et leur procede de preparation
US10065046B2 (en) 2010-07-15 2018-09-04 Fibralign Corporation Conductive biopolymer implant for enhancing tissue repair and regeneration using electromagnetic fields
JP5757514B2 (ja) * 2010-08-30 2015-07-29 国立大学法人東京農工大学 移植用細胞シートの製造方法、移植用細胞シート、及び移植用細胞シートを用いる治療方法
EP2613818B1 (en) 2010-09-10 2019-02-13 Fibralign Corp. Biodegradable multilayer constructs
JP2012065742A (ja) * 2010-09-22 2012-04-05 Atree Co Ltd コラーゲン／アパタイト配向性材料、及びコラーゲン／アパタイト配向性材料の製造方法
JP6031435B2 (ja) * 2011-02-21 2016-11-24 株式会社アトリー コラーゲン材料、及びコラーゲン材料の製造方法
DE102012007911B4 (de) 2012-04-20 2014-07-17 Schaltbau Gmbh Elektrische Steckverbindung
WO2014121303A1 (en) * 2013-02-04 2014-08-07 Northeastern University Mechanochemical collagen assembly
DE202013101349U1 (de) 2013-03-27 2013-04-23 Erich Jaeger Gmbh & Co. Kg Stecker für eine elektrische Stecker-Steckdose-Verbindung zwischen einem Kraftfahrzeug und einem Anhänger
WO2015048344A2 (en) * 2013-09-27 2015-04-02 Tufts University Silk/platelet composition and use thereof
BR112017001049B1 (pt) 2014-09-07 2022-05-10 Ossio Ltd Implante ortopédico compreendendo um material estrutural absorvível
FI3628249T3 (fi) 2014-12-26 2024-03-13 Ossio Ltd Jatkuvalla kuidulla vahvistettuja lääketieteellisiä biokomposiitti-implantteja
RU2590859C1 (ru) * 2015-06-30 2016-07-10 государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) Способ дистантной стимуляции регенерации гепатоцитов
US20180214575A1 (en) * 2015-07-24 2018-08-02 Fibralign Corporation Composition For Targeted Delivery Of Nucleic Acid-Based Therapeutics
CN105126084A (zh) * 2015-07-29 2015-12-09 广州赛莱拉生物基因工程有限公司 一种胶原蛋白组合物及其制备方法
CN105641745B (zh) * 2015-12-28 2018-12-25 四川大学 一种ι型胶原蛋白溶致液晶三维凝胶制备方法
SG11201811090WA (en) 2016-06-27 2019-01-30 Ossio Ltd Fiber reinforced biocomposite medical implants with high mineral content
EP3678566B1 (en) * 2017-09-07 2024-09-04 Ossio Ltd. Fiber reinforced biocomposite threaded implants
WO2020162369A1 (ja) * 2019-02-06 2020-08-13 テルモ株式会社 埋込体留置具及び埋込体
JP7391081B2 (ja) 2019-03-18 2023-12-04 テルモ株式会社 埋込体留置器具
CN110420359B (zh) * 2019-08-07 2021-11-19 北京奥精医疗器械有限责任公司 一种引导组织再生膜及其制备方法
JP7576294B2 (ja) * 2020-04-30 2024-10-31 国立研究開発法人物質・材料研究機構 幹細胞の培養用の足場、幹細胞の培養方法、及びｆｎｗ基材の製造方法。
EP4301427A1 (en) * 2021-03-05 2024-01-10 Northeastern University Design and production of customizable and highly aligned fibrillar collagen scaffolds
RU2766223C1 (ru) * 2021-03-10 2022-02-10 Федеральное государственное бюджетное учреждение науки Институт химии Дальневосточного отделения Российской академии наук (ИХ ДВО РАН) Способ получения биополимерных пленок
IL294542A (en) 2021-07-19 2023-02-01 Ossio Ltd A device with a tube for inserting implants with an adjustable insertion depth
CN114305792B (zh) * 2022-01-11 2025-08-08 东华大学 一种具有逐层诱导性能的韧带再生支架及其制备方法
CN115137882B (zh) * 2022-08-03 2023-07-21 四川大学 利用lb技术模块化组装胶原膜的方法
EP4520356A1 (de) 2023-09-06 2025-03-12 Helmholtz-Zentrum hereon GmbH Biokomposite und verfahren zu ihrer herstellung

Citations (3)

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Publication number Priority date Publication date Assignee Title
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US5744545A (en) * 1988-11-21 1998-04-28 Collagen Corporation Biocompatible adhesive compositions
WO1999047188A1 (en) * 1998-03-17 1999-09-23 Tissue Engineering, Inc. Biopolymer matt for use in tissue repair and reconstruction

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JPS59501319A (ja) * 1983-06-30 1984-07-26 バッテル・ディベロプメント・コ−ポレ−ション コラ−ゲン配向
JPH07213597A (ja) * 1994-02-03 1995-08-15 Bio Eng Lab:Kk 精製コラーゲン様物質の撚り糸、この撚り糸から製造された成形体、及びこれらの製造方法
JPH09122227A (ja) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料およびその製造方法
MXPA06013734A (es) * 2004-05-27 2007-08-14 Arizona Chem Composiciones y articulos que contienen una matriz de polimero entrelazado y un liquido activo inmovilizado, asi como metodos para producir y utilizar las mismas.
GB0415080D0 (en) * 2004-07-05 2004-08-04 Ucl Biomedica Plc Methods for preparing tissue equivalent implants and products thereof
KR20070095327A (ko) * 2004-12-16 2007-09-28 코닌클리케 필립스 일렉트로닉스 엔.브이. 반경 방향 대 수직 방향 누화를 측정 및 최적화하는 방법
US8492332B2 (en) * 2007-04-19 2013-07-23 Fibralign Corporation Oriented collagen-based materials, films and methods of making same
WO2009064437A1 (en) * 2007-11-13 2009-05-22 The Board Of Trustees Of The Leland Stanford Junior University Oriented protein films as a substrate for cell growth

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US5744545A (en) * 1988-11-21 1998-04-28 Collagen Corporation Biocompatible adhesive compositions
WO1999047188A1 (en) * 1998-03-17 1999-09-23 Tissue Engineering, Inc. Biopolymer matt for use in tissue repair and reconstruction

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108379655A (zh) * 2018-05-22 2018-08-10 中山大学 具有三维取向结构的神经移植物及其制备方法和制作设备
CN108379655B (zh) * 2018-05-22 2020-06-30 中山大学 具有三维取向结构的神经移植物及其制备方法和制作设备

Also Published As

Publication number Publication date
EP2331155A2 (en) 2011-06-15
JP2015166369A (ja) 2015-09-24
CN102281907A (zh) 2011-12-14
WO2010019625A2 (en) 2010-02-18
EP2331155B1 (en) 2018-05-09
EP2331155A4 (en) 2013-08-07
JP5939563B2 (ja) 2016-06-22
RU2500432C2 (ru) 2013-12-10
JP6183966B2 (ja) 2017-08-23
BRPI0912470A2 (pt) 2019-10-15
BRPI0912470B1 (pt) 2020-07-21
AU2009282095A1 (en) 2010-02-18
AU2009282095B2 (en) 2015-11-26
BRPI0912470B8 (pt) 2021-06-22
WO2010019625A3 (en) 2010-05-14
RU2011109062A (ru) 2012-09-20
JP2012500203A (ja) 2012-01-05

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