CN102274393A - Medicament for treating cold and preparation method thereof - Google Patents

Medicament for treating cold and preparation method thereof Download PDF

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CN102274393A
CN102274393A CN2011102324849A CN201110232484A CN102274393A CN 102274393 A CN102274393 A CN 102274393A CN 2011102324849 A CN2011102324849 A CN 2011102324849A CN 201110232484 A CN201110232484 A CN 201110232484A CN 102274393 A CN102274393 A CN 102274393A
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radix
medicament
crude drug
medicine
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CN102274393B (en
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俞洋
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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Abstract

The invention discloses a medicament for treating cold and a preparation method thereof. The medicament comprises the following Chinese herbal medicines in part by weight: 5 to 8 parts of fineleaf schizonepeta herb, 6 to 10 parts of incised notopterygium rhizome, 8 to 10 parts of szechuan lovage rhizome, 10 to 15 parts of platycodon root, 10 to 15 parts of heartleaf houttuynia herb, 10 to 15 parts of mulberry root bark,10 to 15 parts of baical skullcap root, 5 to 8 parts of bitter almond kernel, 3 to 5 parts of liquoric root, 10 to 15 parts of bupleurum and 20 to 30 parts of lily. The preparation method comprises the following steps of: weighing the Chinese herbal medicines for later use; adding water, decocting twice, filtering after each time of decoction to obtain filter liquor, mixing the two-time filter liquor, and concentrating under reduced pressure until 5 grams of crude medicaments are contained in 1 milliliter of extract to obtain the medicament for treating the cold. The medicament has the advantages that: the formula is scientific, active ingredients in products are increased, and clinical application proves that the medicament has an obvious curative effect.

Description

A kind of medicine that is used for the treatment of flu and preparation method thereof
Technical field
The present invention relates to the Chinese medicine technical field, relate in particular to a kind of medicine that is used for the treatment of flu and preparation method thereof.
Background technology
Flu is a kind of modal respiratory system disease.Patient also has that heating is heavy, thick sputum is yellow, sore throat except the general symptom that flu such as nasal obstruction, watery nasal discharge, cough, headache is arranged, pain just before cold symptoms usually, the yellow usually or band black of expectorant, characteristics such as constipation.Treatment should be principle with relieving the exterior syndrome with drugs of pungent in flavor and cool in nature.The medicine that is used for the treatment of flu has many kinds.Because Chinese patent medicine has little, the eutherapeutic characteristics of side effect, so favored by people.But clinical practice proves, and is improper if Chinese patent medicine is selected for use, but also delay treatment.The traditional Chinese medical science is divided into four types of wind-chill cold, common cold due to wind heat, summer-wet type common cold and influenzas (influenza) with flu.According to the principle of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, dissimilar flu should be selected different Drug therapys for use.
The common cold due to wind heat patient generally selects for use Chinese patent medicine to treat, but at present commercially available cold granules Clinical Practice proof weak curative effect was able to eat for two weeks sometimes and is not all felt any better.
Summary of the invention
Goal of the invention: first purpose of the present invention is to overcome the deficiencies in the prior art, provides a kind of and can improve effective ingredient amount in the product, the eutherapeutic medicine that is used for the treatment of flu.
Second purpose of the present invention is to provide a kind of above-mentioned preparation method that is used for the treatment of the medicine of flu.
Technical scheme: in order to solve above-mentioned first purpose, the technical solution adopted in the present invention is: a kind of medicine that is used for the treatment of flu comprises the crude drug of following parts by weight: 5~8 parts of Herba Schizonepetae, 6~10 parts of Rhizoma Et Radix Notopterygiis, 8~10 parts of Rhizoma Chuanxiongs, 10~15 parts of Radix Platycodoniss, 10~15 parts of Herba Houttuyniae, 10~15 parts of Cortex Mori, 10~15 parts of Radix Scutellariaes, 5~8 parts of Semen Armeniacae Amarums, 3~5 parts in Radix Glycyrrhizae, 10~15 parts of Radix Bupleuri, 20~30 parts of Bulbus Liliies.
Preferably, the crude drug that comprises following parts by weight: 6 parts of Herba Schizonepetae, 6 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Rhizoma Chuanxiongs, 15 parts of Radix Platycodoniss, 15 parts of Herba Houttuyniae, 10 parts of Cortex Mori, 10 parts of Radix Scutellariaes, 6 parts of Semen Armeniacae Amarums, 3 parts in Radix Glycyrrhizae, 12 parts of Radix Bupleuri, 25 parts of Bulbus Liliies.
In order to solve above-mentioned second purpose, the technical solution adopted in the present invention is: a kind of preparation method that is used for the treatment of the medicine of flu is characterized in that this method comprises the steps:
(1) according to following parts by weight weighting raw materials: 5~8 parts of Herba Schizonepetae, 6~10 parts of Rhizoma Et Radix Notopterygiis, 8~10 parts of Rhizoma Chuanxiongs, 10~15 parts of Radix Platycodoniss, 10~15 parts of Herba Houttuyniae, 10~15 parts of Cortex Mori, 10~15 parts of Radix Scutellariaes, 5~8 parts of Semen Armeniacae Amarums, 3~5 parts in Radix Glycyrrhizae, 10~15 parts of Radix Bupleuri, 20~30 parts of Bulbus Liliies; Standby;
(2) above-mentioned each crude drug is decocted with water twice, for the first time amount of water is 3~5 times of crude drug gross weight, decoct and extract 1h, for the second time amount of water is 2~3 times of crude drug gross weight, decocts and extracts 30min, all filters after each the decoction, get filtrate, merge filtrate twice, be evaporated to the extractum that contains 5g crude drug/ml, promptly get the medicine of described treatment flu.
Beneficial effect: compared with prior art, advantage of the present invention is: scientific formulation, can improve effective ingredient amount in the product, and prove medicine evident in efficacy through clinical use.
The specific embodiment
Further set forth the present invention below by embodiment, should understand these embodiment and only be used to the present invention is described and be not used in and limit the scope of the invention.
Embodiment 1: a kind of medicine that is used for the treatment of flu, mainly make: 6 parts of Herba Schizonepetae, 6 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Rhizoma Chuanxiongs, 15 parts of Radix Platycodoniss, 15 parts of Herba Houttuyniae, 10 parts of Cortex Mori, 10 parts of Radix Scutellariaes, 6 parts of Semen Armeniacae Amarums, 3 parts in Radix Glycyrrhizae, 12 parts of Radix Bupleuri, 25 parts of Bulbus Liliies by the crude drug of following parts by weight.
At first according to following parts by weight weighting raw materials, then above-mentioned each crude drug is decocted with water twice, for the first time amount of water is 5 times of crude drug gross weight, decocts and extracts 1h, and amount of water is 3 times of crude drug gross weight for the second time, decoct and extract 30min, all filter after each the decoction, get filtrate, merge filtrate twice, be evaporated to the extractum that contains 5g crude drug/ml, promptly get the medicine of described treatment flu.
Embodiment 2: a kind of medicine that is used for the treatment of flu, mainly make: 5 parts of Herba Schizonepetae, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Chuanxiongs, 10 parts of Radix Platycodoniss, 10 parts of Herba Houttuyniae, 15 parts of Cortex Mori, 15 parts of Radix Scutellariaes, 8 parts of Semen Armeniacae Amarums, 5 parts in Radix Glycyrrhizae, 15 parts of Radix Bupleuri, 30 parts of Bulbus Liliies by the crude drug of following parts by weight; Standby;
At first according to following parts by weight weighting raw materials, then above-mentioned each crude drug is decocted with water twice, for the first time amount of water is 3 times of crude drug gross weight, decocts and extracts 1h, and amount of water is 2 times of crude drug gross weight for the second time, decoct and extract 30min, all filter after each the decoction, get filtrate, merge filtrate twice, be evaporated to the extractum that contains 5g crude drug/ml, promptly get the medicine of described treatment flu.
Embodiment 3: a kind of medicine that is used for the treatment of flu, mainly make: 8 parts of Herba Schizonepetae, 10 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Rhizoma Chuanxiongs, 12 parts of Radix Platycodoniss, 12 parts of Herba Houttuyniae, 12 parts of Cortex Mori, 12 parts of Radix Scutellariaes, 5 parts of Semen Armeniacae Amarums, 4 parts in Radix Glycyrrhizae, 10 parts of Radix Bupleuri, 20 parts of Bulbus Liliies by the crude drug of following parts by weight; Standby;
At first according to following parts by weight weighting raw materials, then above-mentioned each crude drug is decocted with water twice, for the first time amount of water is 4 times of crude drug gross weight, decocts and extracts 1h, and amount of water is 3 times of crude drug gross weight for the second time, decoct and extract 30min, all filter after each the decoction, get filtrate, merge filtrate twice, be evaporated to the extractum that contains 5g crude drug/ml, promptly get the medicine of described treatment flu.
Further set forth beneficial effect of the present invention below by clinical trial.
Select 100 common cold due to wind heat patients to carry out system's clinical observation according to conditions of patients, the patient is divided into test group and matched group at random, every group 50 people, test group is treated according to the prescription in embodiment 1 or the experimental example 2; Matched group is taken commercially available coldrex treatment;
Usage and dosage: be decocted in water for oral dose 2 times on the one.7 days is a course of treatment, totally 3 courses of treatment.
Efficacy assessment standard:
Produce effects: the phenomenon of not having heating, feeling of fullness in the head, cough, laryngopharynx swelling and pain, nasal obstruction, watery nasal discharge after course of treatment.
Effectively: do not have the phenomenon of heating, feeling of fullness in the head, cough, laryngopharynx swelling and pain after course of treatment, symptom after two courses of treatment
Disappear entirely.
Invalid: symptom does not still have obvious improvement after two courses of treatment.
The curative effect of test group and matched group clinical trial is as shown in the table:
Figure BDA0000083232410000031
Test data statistics in the last table shows that take the patient of this medicine, what significant curative effect was arranged accounts for 40%, accounts for 10% and matched group has a significant curative effect, and hence one can see that, and test group has the matched group that is far longer than of significant curative effect, and the value of clinical expansion is arranged.

Claims (3)

1. medicine that is used for the treatment of flu, it is characterized in that, comprise the crude drug of following parts by weight: 5~8 parts of Herba Schizonepetae, 6~10 parts of Rhizoma Et Radix Notopterygiis, 8~10 parts of Rhizoma Chuanxiongs, 10~15 parts of Radix Platycodoniss, 10~15 parts of Herba Houttuyniae, 10~15 parts of Cortex Mori, 10~15 parts of Radix Scutellariaes, 5~8 parts of Semen Armeniacae Amarums, 3~5 parts in Radix Glycyrrhizae, 10~15 parts of Radix Bupleuri, 20~30 parts of Bulbus Liliies.
2. a kind of medicine that is used for the treatment of flu according to claim 1, it is characterized in that, comprise the crude drug of following parts by weight: 6 parts of Herba Schizonepetae, 6 parts of Rhizoma Et Radix Notopterygiis, 10 parts of Rhizoma Chuanxiongs, 15 parts of Radix Platycodoniss, 15 parts of Herba Houttuyniae, 10 parts of Cortex Mori, 10 parts of Radix Scutellariaes, 6 parts of Semen Armeniacae Amarums, 3 parts in Radix Glycyrrhizae, 12 parts of Radix Bupleuri, 25 parts of Bulbus Liliies.
3. a kind of preparation method that is used for the treatment of the medicine of flu according to claim 1 is characterized in that this method comprises the steps:
(1) according to following parts by weight weighting raw materials: 5~8 parts of Herba Schizonepetae, 6~10 parts of Rhizoma Et Radix Notopterygiis, 8~10 parts of Rhizoma Chuanxiongs, 10~15 parts of Radix Platycodoniss, 10~15 parts of Herba Houttuyniae, 10~15 parts of Cortex Mori, 10~15 parts of Radix Scutellariaes, 5~8 parts of Semen Armeniacae Amarums, 3~5 parts in Radix Glycyrrhizae, 10~15 parts of Radix Bupleuri, 20~30 parts of Bulbus Liliies; Standby;
(2) above-mentioned each crude drug is decocted with water twice, for the first time amount of water is 3~5 times of crude drug gross weight, decoct and extract 1h, for the second time amount of water is 2~3 times of crude drug gross weight, decocts and extracts 30min, all filters after each the decoction, get filtrate, merge filtrate twice, be evaporated to the extractum that contains 5g crude drug/ml, promptly get the medicine of described treatment flu.
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1276216A (en) * 2000-05-25 2000-12-13 赵国林 Process for preparing non-decoction Chinese medicine
CN1729992A (en) * 2005-08-12 2006-02-08 邵建国 Externally applied bath liquid for epidemic wind-cold type cold
CN101077371A (en) * 2006-05-22 2007-11-28 赵军 Method for treating wind-cold common cold
CN101254255A (en) * 2008-04-11 2008-09-03 刘宗升 Traditional Chinese medicine preparation for curing cold
CN101703602A (en) * 2009-10-23 2010-05-12 成钢 Perfume satchel (bag) for preventing and curing influenza A virus subtype H1N1 by nano element traditional Chinese medicine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1276216A (en) * 2000-05-25 2000-12-13 赵国林 Process for preparing non-decoction Chinese medicine
CN1729992A (en) * 2005-08-12 2006-02-08 邵建国 Externally applied bath liquid for epidemic wind-cold type cold
CN101077371A (en) * 2006-05-22 2007-11-28 赵军 Method for treating wind-cold common cold
CN101254255A (en) * 2008-04-11 2008-09-03 刘宗升 Traditional Chinese medicine preparation for curing cold
CN101703602A (en) * 2009-10-23 2010-05-12 成钢 Perfume satchel (bag) for preventing and curing influenza A virus subtype H1N1 by nano element traditional Chinese medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《陕西中医函授》 20011231 王冠彬等 败毒散加减治疗小儿感冒62例临床观察 , 第04期 *

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