CN102254150A - 细胞群的变化的测定 - Google Patents

细胞群的变化的测定 Download PDF

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Publication number
CN102254150A
CN102254150A CN2011101579840A CN201110157984A CN102254150A CN 102254150 A CN102254150 A CN 102254150A CN 2011101579840 A CN2011101579840 A CN 2011101579840A CN 201110157984 A CN201110157984 A CN 201110157984A CN 102254150 A CN102254150 A CN 102254150A
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cell
embryo
images
difference image
division
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尼尔斯·B·拉姆辛
于尔根·伯恩特森
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Unisense Fertilitech AS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G06T7/0016—Biomedical image inspection using an image reference approach involving temporal comparison
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/20—Analysis of motion
    • G06T7/254—Analysis of motion involving subtraction of images
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2200/00—Indexing scheme for image data processing or generation, in general
    • G06T2200/24—Indexing scheme for image data processing or generation, in general involving graphical user interfaces [GUIs]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
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  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
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  • Quality & Reliability (AREA)
  • Computer Hardware Design (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
CN2011101579840A 2005-10-14 2006-10-16 细胞群的变化的测定 Pending CN102254150A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US72679505P 2005-10-14 2005-10-14
DKPA200501438 2005-10-14
US60/726,795 2005-10-14
DKPA200501438 2005-10-14
US81411506P 2006-06-16 2006-06-16
DKPA200600821 2006-06-16
DKPA200600821 2006-06-16
US60/814,115 2006-06-16

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CN200680047484.9A Expired - Fee Related CN101331500B (zh) 2005-10-14 2006-10-16 细胞群的变化的测定

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US (1) US8265357B2 (https=)
EP (1) EP1949297B1 (https=)
JP (2) JP5451073B2 (https=)
CN (2) CN102254150A (https=)
ES (1) ES2549205T3 (https=)
WO (1) WO2007042044A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104382589A (zh) * 2014-12-09 2015-03-04 南京大学 基于部分按段重采样的胎儿心电图分离提取方法
CN104755608A (zh) * 2012-08-30 2015-07-01 尤尼森斯繁殖技术公司 体外培养胚胎的自动化监控
CN106327508A (zh) * 2016-08-23 2017-01-11 马跃生 Ki67指数自动分析方法
CN103903015B (zh) * 2014-03-20 2017-02-22 南京信息工程大学 一种细胞有丝分裂检测方法
CN110023481A (zh) * 2016-11-30 2019-07-16 索尼公司 信息处理设备、观察系统、信息处理方法和程序
CN112862742A (zh) * 2019-11-27 2021-05-28 静宜大学 利用光动力学技术的人工智能的细胞检测方法及其系统

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7672369B2 (en) 2002-02-13 2010-03-02 Reify Corporation Method and apparatus for acquisition, compression, and characterization of spatiotemporal signals
US7838727B2 (en) * 2004-11-04 2010-11-23 Advanced Cell Technology, Inc. Derivation of embryonic stem cells
US8265357B2 (en) 2005-10-14 2012-09-11 Unisense Fertilitech A/S Determination of a change in a cell population
EP2035548B1 (en) * 2006-06-16 2010-08-11 Unisense Fertilitech A/S Embryo quality assessment based on blastomere division and movement
JP4973162B2 (ja) * 2006-12-01 2012-07-11 株式会社ニコン 画像処理装置、画像処理プログラム及び観察システム
US7940978B2 (en) * 2007-06-05 2011-05-10 General Electric Company Automatic characterization of cellular motion
JP5143227B2 (ja) 2007-06-29 2013-02-13 ウニセンス フェルティリテック アー／エス 顕微鏡対象物の監視および／または培養用の機器、システムおよび方法
JP4968595B2 (ja) * 2008-07-23 2012-07-04 株式会社ニコン 細胞の状態判別手法及び細胞観察の画像処理装置
US8515143B2 (en) * 2009-01-09 2013-08-20 Dai Nippon Printing Co., Ltd. Embryo quality evaluation assistance system, embryo quality evaluation assistance apparatus and embryo quality evaluation assistance method
JPWO2010098105A1 (ja) * 2009-02-26 2012-08-30 国立大学法人名古屋大学 培養状態評価装置、培養状態評価方法、インキュベータおよびプログラム
EP2441827B1 (en) * 2009-06-12 2016-04-13 Nikon Corporation Technique for determining the state of a cell mass, image processing program and image processing device using said technique, and method for producing a cell mass
EP2446251B1 (en) * 2009-06-25 2018-12-05 Phase Holographic Imaging Phi AB Analysis of ova or embryos with digital holographic imaging
JPWO2011013319A1 (ja) * 2009-07-31 2013-01-07 株式会社ニコン 細胞塊の成熟判定手法、この手法を用いた画像処理プログラム及び画像処理装置、並びに細胞塊の製造方法
PL2827150T3 (pl) * 2009-08-22 2021-05-31 The Board Of Trustees Of The Leland Stanford Junior University Obrazowanie i ocena zarodków, oocytów i komórek macierzystych
CN102906789B (zh) 2010-03-29 2017-05-17 索尼公司 数据处理装置、数据处理方法、图像处理装置和方法以及程序
GB201006046D0 (en) 2010-04-12 2010-05-26 Ge Healthcare Uk Ltd System and method for determining motion of a biological object
JP5807288B2 (ja) 2010-06-30 2015-11-10 大日本印刷株式会社 体外培養による胚の製造方法、並びに胚を選別するための方法、装置、及びシステム
CA2812776C (en) * 2010-09-27 2022-05-17 Auxogyn, Inc. Apparatus, method, and system for the automated imaging and evaluation of embryos, oocytes, and stem cells
CA2827945C (en) 2011-02-23 2021-10-12 The Board Of Trustees Of The Leland Stanford Junior University Methods of detecting aneuploidy in human embryos
EP2714895B1 (en) 2011-05-31 2017-10-04 Unisense Fertilitech A/S Embryo quality assessment based on blastomere cleavage and morphology
AU2012280743A1 (en) * 2011-07-02 2014-01-16 Unisense Fertilitech A/S Adaptive embryo selection criteria optimized through iterative customization and collaboration
US9070004B2 (en) 2012-05-03 2015-06-30 General Electric Company Automatic segmentation and characterization of cellular motion
CN104508123B (zh) 2012-05-31 2017-08-22 尤尼森斯繁殖技术公司 基于胚泡发育的胚胎质量评估
ITRM20120257A1 (it) * 2012-06-05 2013-12-06 Advanced Comp Systems A C S S P A Metodo per la quantificazione del grado di regolarità morfologica della zona pellucida in embrioni e ovociti.
EP2864475A1 (en) 2012-06-25 2015-04-29 Unisense Fertilitech A/S Method and apparatus
US9123120B2 (en) * 2012-08-24 2015-09-01 DR Vision Technologies LLC Progressive decision for cellular process selection
BR102012031953B1 (pt) * 2012-12-14 2020-04-07 Univ Estadual Paulista Julio De Mesquita Filho Unesp método para determinação da viabilidade e qualidade de embriões
HK1217762A1 (zh) 2013-01-08 2017-01-20 The Brigham And Women's Hospital,Inc. 用於評價卵母細胞和胚胎的代謝成像方法
GB201301043D0 (en) 2013-01-21 2013-03-06 Chronos Therapeutics Ltd Method for assessing cell aging
US10241108B2 (en) 2013-02-01 2019-03-26 Ares Trading S.A. Abnormal syngamy phenotypes observed with time lapse imaging for early identification of embryos with lower development potential
US9177192B2 (en) 2013-02-28 2015-11-03 Progyny, Inc. Apparatus, method, and system for image-based human embryo cell classification
JPWO2015045183A1 (ja) * 2013-09-30 2017-03-09 富士通株式会社 コロニー画像検査プログラム、コロニー画像検査方法及びコロニー画像検査装置
GB2524082A (en) 2014-03-14 2015-09-16 Unisense Fertilitech As Methods and apparatus for analysing embryo development
ES2837840T3 (es) 2014-03-20 2021-07-01 Ares Trading Sa Medida cuantitativa de la cinética de desarrollo de la morfología de mórula y blastocisto humanos
WO2015161045A1 (en) * 2014-04-16 2015-10-22 President And Fellows Of Harvard College Non-linear imaging systems and methods for assisted reproductive technologies
WO2015192352A1 (zh) * 2014-06-19 2015-12-23 湖南光琇高新生命科技有限公司 一种根据分裂行为对体外受精治疗胚胎进行评估的等级分类方法
ES2959649T3 (es) 2014-08-28 2024-02-27 Cedars Sinai Medical Center Detección temprana del cáncer de pulmón mediante fenotipación por metilación del ADN de células derivadas del esputo
JP6746945B2 (ja) * 2015-06-30 2020-08-26 ソニー株式会社 情報処理装置、情報処理システム及び情報処理方法
US10410096B2 (en) * 2015-07-09 2019-09-10 Qualcomm Incorporated Context-based priors for object detection in images
US11494578B1 (en) * 2015-09-21 2022-11-08 Ares Trading S.A. Systems and methods for automated assessment of embryo quality using image based features
US10510143B1 (en) * 2015-09-21 2019-12-17 Ares Trading S.A. Systems and methods for generating a mask for automated assessment of embryo quality
JP6742724B2 (ja) * 2015-12-28 2020-08-19 シスメックス株式会社 細胞領域決定方法、細胞撮像システム、細胞画像の処理装置及びコンピュータプログラム
USD817966S1 (en) * 2016-01-26 2018-05-15 Sony Corporation Portion of display panel or screen with animated graphical user interface
JP2018014991A (ja) 2016-07-13 2018-02-01 ソニー株式会社 情報処理装置、情報処理方法及び情報処理システム
JP2018022216A (ja) * 2016-08-01 2018-02-08 ソニー株式会社 情報処理装置、情報処理方法、及びプログラム
JP6977293B2 (ja) * 2017-03-31 2021-12-08 ソニーグループ株式会社 情報処理装置、情報処理方法、プログラム及び観察システム
CN110520897A (zh) * 2017-03-31 2019-11-29 索尼公司 信息处理装置、信息处理方法、程序和观察系统
WO2019036388A1 (en) * 2017-08-14 2019-02-21 Raytheon Company ALGORITHM OF SUBTRACTION FOR DETECTION OF TUMORS
US11321831B2 (en) 2017-09-29 2022-05-03 The Brigham And Women's Hospital, Inc. Automated evaluation of human embryos
FR3077136A1 (fr) * 2018-01-19 2019-07-26 I2S Dispositif d'observation d'une cellule ou d'un ensemble de cellules vivantes
WO2019169432A1 (en) * 2018-03-07 2019-09-12 Verdict Holdings Pty Ltd Methods for identifying biological material by microscopy
US10552957B2 (en) * 2018-03-24 2020-02-04 Dan Nayot Methods and systems for determining quality of an oocyte
HUE052890T2 (hu) * 2018-06-06 2021-05-28 Flooring Technologies Ltd Eljárás hordozóanyagokon lévõ dekornyomatok online minõségellenõrzésére
EP3853763A1 (en) * 2018-09-20 2021-07-28 Aivf Ltd Image feature detection
US11475558B2 (en) 2019-11-13 2022-10-18 Raytheon Company Organ isolation in scan data
US11282209B2 (en) 2020-01-10 2022-03-22 Raytheon Company System and method for generating contours
CN113687601B (zh) * 2020-05-18 2022-11-29 联华电子股份有限公司 设备的自动调整方法及应用其的智能调整装置
US20220076780A1 (en) * 2020-09-04 2022-03-10 10X Genomics, Inc. Systems and methods for identifying cell-associated barcodes in mutli-genomic feature data from single-cell partitions
US11562512B2 (en) 2020-12-09 2023-01-24 Raytheon Company System and method for generating and displaying contours
US11893745B2 (en) 2020-12-09 2024-02-06 Raytheon Company System and method for generating and displaying contours
JP7636917B2 (ja) * 2021-03-16 2025-02-27 本田技研工業株式会社 移動体の移動量を推定する情報処理装置、情報処理方法、及びプログラム
EP4145389A1 (en) * 2021-09-01 2023-03-08 SCREEN Holdings Co., Ltd. Image processing method, fertilized egg evaluation method, computer program and recording medium
CN114664048B (zh) * 2022-05-26 2022-08-12 环球数科集团有限公司 一种基于卫星遥感监测的火情监测及火灾预警方法
AU2024249120A1 (en) * 2023-03-29 2025-08-28 Vytelle Llc Method and system of predicting pregnancy outcomes and quality grades in mammalian embryos
CN120318198B (zh) * 2025-04-15 2025-10-14 四川锦欣西囡妇女儿童医院有限公司 基于样本库的胚胎智能化筛选系统及方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3618734A (en) 1969-06-10 1971-11-09 Res Foundation Of Children S H Specimen incubator
GB1426786A (en) 1973-09-12 1976-03-03 British Petroleum Co Microbiological method for estimating the toxicity of liquid industrial effluents
DE2940446C2 (de) 1979-10-05 1982-07-08 B. Braun Melsungen Ag, 3508 Melsungen Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen
US4724543A (en) 1985-09-10 1988-02-09 Beckman Research Institute, City Of Hope Method and apparatus for automatic digital image analysis
NL8600396A (nl) 1986-02-17 1987-09-16 Rijkslandbouwhogeschool Werkwijze voor het bepalen van de respiratiesnelheid van een respirerend materiaal in een continue processtroom alsmede een voor een dergelijke toepassing geschikte inrichting.
JP2662215B2 (ja) 1986-11-19 1997-10-08 株式会社日立製作所 細胞保持装置
JP2559760B2 (ja) 1987-08-31 1996-12-04 株式会社日立製作所 細胞搬送方法
JP2564322B2 (ja) 1987-10-07 1996-12-18 株式会社日立製作所 細胞融合装置
DE3836716A1 (de) * 1988-10-28 1990-05-03 Zeiss Carl Fa Verfahren zur auswertung von zellbildern
CA2072115A1 (en) 1989-10-30 1991-05-01 Dallas E. Hughes Expression of bacterial hemoglobin and enhancement of expression of cloned and native products in streptomyces
DE69024631T2 (de) 1990-03-29 1996-09-19 Avl Photronics Corp Verfahren und Apparat zum Nachweis biologischer Aktivitäten in einer Probe
EP0585349A4 (en) 1991-05-14 1994-12-07 Sinai School Medicine METHOD AND APPARATUS FOR IN-VITRO FERTILIZATION.
US5196168A (en) 1991-12-19 1993-03-23 Eastman Kodak Company Incubator with positioning device for slide elements
AU658079B2 (en) 1992-09-28 1995-03-30 Becton Dickinson & Company Cell culture insert
US5763279A (en) 1993-09-09 1998-06-09 Synthecon, Inc. Gas permeable bioreactor and method of use
DE69528440T2 (de) 1994-12-20 2003-06-18 Cosmo Oil Co. Ltd., Tokio/Tokyo 5-Aminolävulinsäure produzierender Mikroorganismus
JP2000500580A (ja) 1995-11-22 2000-01-18 ユニセンス・エイピイエス マイクロセンサおよびそのマイクロセンサの使用方法
WO1998005753A1 (de) 1996-08-05 1998-02-12 Heraeus Instruments GmbH & Co.KG Objekt-lagervorrichtung, lagerstation und klimaschrank
DK172855B1 (da) 1996-11-12 1999-08-16 Unisense Aps Fremgangsmåde til måling af koncentrationen af et medium i et miljø, mikrosensor til brug ved fremgangsmåden og anvendelse
US6306491B1 (en) 1996-12-20 2001-10-23 Gore Enterprise Holdings, Inc. Respiratory aids
US5968340A (en) 1997-04-07 1999-10-19 Marine Biological Laboratory Polarographic self-referencing probe and method for using
US6228636B1 (en) 1998-09-21 2001-05-08 Matsushita Electric Industrial Co., Ltd. Incubator
DE19903506C2 (de) 1999-01-29 2002-04-04 Inst Chemo Biosensorik Verfahren, Gefäß und Vorrichtung zur Überwachung der Stoffwechselaktivität von Zellkulturen in flüssigen Medien
US6391577B1 (en) 1999-03-03 2002-05-21 Susan R. Mikkelsen Rapid electrochemical assay for antibiotic and cytotoxic drug susceptibility in microorganisms
AU5061300A (en) 1999-06-30 2001-01-22 Danish Institute of Agricultural Sciences, The Microchamber for embryo cell culture
EP1214593A2 (en) 1999-06-30 2002-06-19 Knoll GmbH Screening for compounds modulating mitochondrial proton leak
US6998249B1 (en) 1999-09-27 2006-02-14 Pharmacia & Upjohn Company Toxicity screening method
US6395555B1 (en) 1999-10-14 2002-05-28 David F. Wilson Method and apparatus for determining the effect of a drug on cells
RU2187111C2 (ru) 1999-11-02 2002-08-10 Кубанский государственный университет Способ определения функционального состояния фолликулов млекопитающих
EP1134583A1 (en) 2000-03-17 2001-09-19 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Measuring metabolic rate changes
DE10017192A1 (de) 2000-04-07 2001-10-11 Kendro Lab Prod Gmbh Brutschrank sowie Verfahren zur Entriegelung und Verwendung
JP2001330582A (ja) 2000-05-24 2001-11-30 Japan Science & Technology Corp 細胞呼吸活性評価方法及びその装置
JP3442357B2 (ja) 2000-08-25 2003-09-02 株式会社日立製作所 両生類卵母細胞試料導入装置、両生類卵母細胞試料導入システム、両生類卵母細胞試料導入方法、両生類卵母細胞の製造方法、両生類卵母細胞及びそれを販売又は譲渡する方法、スクリーニング用のセンサーとして用いる方法、容器、及び解析方法
JP3693907B2 (ja) 2000-10-13 2005-09-14 独立行政法人科学技術振興機構 哺乳動物胚の無侵襲的品質評価方法及びその装置
US6434320B1 (en) 2000-10-13 2002-08-13 Comtrak Technologies, Llc Method of searching recorded digital video for areas of activity
EP1339017A4 (en) * 2000-12-01 2007-08-29 Japan Science & Tech Corp NUCLEAR RANGE DETECTION METHOD AND NUCLEAR GENEALOGY PRODUCTION PROCESS
US6555365B2 (en) 2000-12-07 2003-04-29 Biocrystal, Ltd. Microincubator comprising a cell culture apparatus and a transparent heater
US7015031B2 (en) 2002-01-24 2006-03-21 Genx International, Inc. Biological specimen-culturing system and method with onboard specimen development sensors
US7672369B2 (en) 2002-02-13 2010-03-02 Reify Corporation Method and apparatus for acquisition, compression, and characterization of spatiotemporal signals
TWI249574B (en) 2002-11-19 2006-02-21 Sanyo Electric Co Preserving device
KR20060058664A (ko) 2002-12-23 2006-05-30 유니센스 에이/에스 실질적인 구형 대사 입자의 개별 대사율의 비침해적 측정방법 및 기구
US7372985B2 (en) * 2003-08-15 2008-05-13 Massachusetts Institute Of Technology Systems and methods for volumetric tissue scanning microscopy
US7239719B2 (en) 2003-08-22 2007-07-03 Bbn Technologies Corp. Automatic target detection and motion analysis from image data
JP4454998B2 (ja) * 2003-09-29 2010-04-21 株式会社ニコン 細胞観察装置および細胞観察方法
WO2005039181A1 (ja) 2003-10-21 2005-04-28 Matsushita Electric Industrial Co., Ltd. 監視装置
JP4439882B2 (ja) 2003-11-14 2010-03-24 キヤノン株式会社 放射線画像処理装置及び処理方法
JP2005168341A (ja) 2003-12-09 2005-06-30 Olympus Corp 生体試料観察装置
GB2409029A (en) * 2003-12-11 2005-06-15 Sony Uk Ltd Face detection
US7336401B2 (en) * 2003-12-19 2008-02-26 Xerox Corporation Systems and methods for estimating an image marking process using event mapping of scanned image attributes
CN1236302C (zh) * 2003-12-19 2006-01-11 武汉大学 一种多光谱细胞涂片自动分析仪及其用于宫颈细胞的分析方法
US7187286B2 (en) 2004-03-19 2007-03-06 Applera Corporation Methods and systems for using RFID in biological field
JP4504089B2 (ja) 2004-05-10 2010-07-14 富士通株式会社 マイクロインジェクション装置およびマイクロインジェクション方法
JP4749684B2 (ja) 2004-07-02 2011-08-17 株式会社ジェイテック インキュベータ及びそれに用いる培養カセット
JP2006034256A (ja) 2004-07-30 2006-02-09 Sanyo Electric Co Ltd 保管装置
JPWO2007004385A1 (ja) 2005-07-05 2009-01-22 株式会社ニコン 培養装置
US8265357B2 (en) 2005-10-14 2012-09-11 Unisense Fertilitech A/S Determination of a change in a cell population
JP2007334141A (ja) 2006-06-16 2007-12-27 Sanyo Electric Co Ltd 培養物観察システム
EP2035548B1 (en) 2006-06-16 2010-08-11 Unisense Fertilitech A/S Embryo quality assessment based on blastomere division and movement
EP2031051B1 (en) 2006-06-16 2021-05-19 PHC Holdings Corporation Culture monitoring system
JP5143227B2 (ja) 2007-06-29 2013-02-13 ウニセンス フェルティリテック アー／エス 顕微鏡対象物の監視および／または培養用の機器、システムおよび方法

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104755608A (zh) * 2012-08-30 2015-07-01 尤尼森斯繁殖技术公司 体外培养胚胎的自动化监控
CN103903015B (zh) * 2014-03-20 2017-02-22 南京信息工程大学 一种细胞有丝分裂检测方法
CN104382589A (zh) * 2014-12-09 2015-03-04 南京大学 基于部分按段重采样的胎儿心电图分离提取方法
CN106327508A (zh) * 2016-08-23 2017-01-11 马跃生 Ki67指数自动分析方法
CN106327508B (zh) * 2016-08-23 2019-04-02 马跃生 Ki67指数自动分析方法
CN110023481A (zh) * 2016-11-30 2019-07-16 索尼公司 信息处理设备、观察系统、信息处理方法和程序
CN112862742A (zh) * 2019-11-27 2021-05-28 静宜大学 利用光动力学技术的人工智能的细胞检测方法及其系统

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CN101331500B (zh) 2015-04-29
WO2007042044A1 (en) 2007-04-19
EP1949297A1 (en) 2008-07-30
US20080247628A1 (en) 2008-10-09
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