HK1217762A1 - 用於評價卵母細胞和胚胎的代謝成像方法 - Google Patents

用於評價卵母細胞和胚胎的代謝成像方法

Info

Publication number
HK1217762A1
HK1217762A1 HK16105702.0A HK16105702A HK1217762A1 HK 1217762 A1 HK1217762 A1 HK 1217762A1 HK 16105702 A HK16105702 A HK 16105702A HK 1217762 A1 HK1217762 A1 HK 1217762A1
Authority
HK
Hong Kong
Prior art keywords
oocytes
embryos
assessment
imaging methods
metabolic imaging
Prior art date
Application number
HK16105702.0A
Other languages
English (en)
Inventor
Catherine Racowsky
Manqi Deng
Daniel Needleman
Original Assignee
The Brigham And Womens Hospitalinc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Brigham And Womens Hospitalinc filed Critical The Brigham And Womens Hospitalinc
Publication of HK1217762A1 publication Critical patent/HK1217762A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6423—Spectral mapping, video display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06193—Secundary in-situ sources, e.g. fluorescent particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation
    • G01N2201/12746—Calibration values determination
    • G01N2201/12761—Precalibration, e.g. for a given series of reagents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Reproductive Health (AREA)
  • Optics & Photonics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
HK16105702.0A 2013-01-08 2016-05-18 用於評價卵母細胞和胚胎的代謝成像方法 HK1217762A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361750061P 2013-01-08 2013-01-08
PCT/US2014/010435 WO2014110008A1 (en) 2013-01-08 2014-01-07 Metabolic imaging methods for assessment of oocytes and embryos

Publications (1)

Publication Number Publication Date
HK1217762A1 true HK1217762A1 (zh) 2017-01-20

Family

ID=51167314

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105702.0A HK1217762A1 (zh) 2013-01-08 2016-05-18 用於評價卵母細胞和胚胎的代謝成像方法

Country Status (13)

Country Link
US (3) US20150346100A1 (zh)
EP (1) EP2943777B1 (zh)
JP (1) JP2016505263A (zh)
KR (1) KR20150107774A (zh)
CN (1) CN105008900A (zh)
AU (1) AU2014205650A1 (zh)
BR (1) BR112015016375A2 (zh)
CA (1) CA2897530A1 (zh)
HK (1) HK1217762A1 (zh)
IL (1) IL239826A0 (zh)
RU (1) RU2015127205A (zh)
SG (1) SG11201505326QA (zh)
WO (1) WO2014110008A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013044182A1 (en) 2011-09-22 2013-03-28 The George Washington University Systems and methods for visualizing ablated tissue
EP2757933B1 (en) 2011-09-22 2019-02-06 The George Washington University Systems for visualizing ablated tissue
JP6737705B2 (ja) * 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム
WO2015077474A1 (en) 2013-11-20 2015-05-28 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
US9984278B2 (en) 2014-04-16 2018-05-29 President And Fellows Of Harvard College Non-linear imaging systems and methods for assisted reproductive technologies
CN107613849B (zh) 2014-11-03 2021-05-04 乔治华盛顿大学 用于损伤评估的系统和方法
US10143517B2 (en) 2014-11-03 2018-12-04 LuxCath, LLC Systems and methods for assessment of contact quality
WO2016118557A1 (en) * 2015-01-20 2016-07-28 President And Fellows Of Harvard College Assessing metabolic condition of sperm
CZ307467B6 (cs) * 2015-03-03 2018-09-26 Jihočeská Univerzita V Českých Budějovicích, Fakulta Rybářství A Ochrany Vod, Jihočeské Výzkumné Centrum Akvakultury A Biodiverzity Hydrocenóz, Výzkumný Ústav Rybářský A Hydrobiologický Způsob značení zárodečných buněk, zejména primordiálních gonocytů chrupavčitých ryb
WO2016148905A1 (en) * 2015-03-19 2016-09-22 President And Fellows Of Harvard College Flim for differentiating old and young oocytes
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
DK3455340T3 (da) * 2016-06-30 2020-07-20 Esco Medical Aps Apparat til inkubation af et biologisk materiale
US10712272B2 (en) * 2016-09-27 2020-07-14 Trustees Of Tufts College System and method for assessing cellular metabolic activity
US10552957B2 (en) * 2018-03-24 2020-02-04 Dan Nayot Methods and systems for determining quality of an oocyte
WO2020047133A1 (en) * 2018-08-29 2020-03-05 Wisconsin Alumni Research Foundation Systems and methods for sorting t cells by activation state
US11386559B2 (en) * 2019-04-03 2022-07-12 The Regents Of The University Of California System and method for tissue viability screening
CN110969616B (zh) * 2019-12-13 2020-10-27 北京推想科技有限公司 评价卵母细胞质量的方法及装置
CA3169330A1 (en) * 2020-02-27 2021-09-02 Jang Lawrence YOO Contactless inspection of reproductive cellular structures using optical measurement of biomechanical properties
WO2022212950A1 (en) * 2021-04-02 2022-10-06 Optiva Fertility, Inc. Artificial intelligence methods for predicting embryo viability based on microscopy methods
US20240026420A1 (en) * 2022-07-12 2024-01-25 Sartorius Bioanalytical Instruments, Inc. FRET Biosensor for Detecting and Reporting NAD+/NADH Ratio Changes

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541081A (en) * 1994-03-22 1996-07-30 President And Fellows Of Harvard College Process for assessing oocyte and embryo quality
US7049480B1 (en) 2000-09-01 2006-05-23 Avigenics, Inc. Methods of enucleating an avian oocyte or zygote using two-photon laser scanning microscopy
DK2283724T3 (en) 2002-08-01 2016-04-04 Xy Llc Heterospermic insemination to assess sperm function
US7907769B2 (en) 2004-05-13 2011-03-15 The Charles Stark Draper Laboratory, Inc. Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation
JP5547868B2 (ja) 2004-09-14 2014-07-16 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド 顕微鏡系およびこれを用いた方法
WO2006055761A1 (en) 2004-11-17 2006-05-26 Mosaic Reproductive Health And Genetics, Llc Methods of determining human egg competency
CN102254150A (zh) 2005-10-14 2011-11-23 尤尼森斯繁殖技术公司 细胞群的变化的测定
US7981399B2 (en) * 2006-01-09 2011-07-19 Mcgill University Method to determine state of a cell exchanging metabolites with a fluid medium by analyzing the metabolites in the fluid medium
WO2007115297A2 (en) * 2006-04-04 2007-10-11 Cambridge Research And Instrumentation, Inc. Assessing oocyte quality using birefringence imaging
WO2008022210A2 (en) 2006-08-15 2008-02-21 The Board Of Regents Of The University Of Texas System Methods, compositions and systems for analyzing imaging data
CA2650146A1 (en) * 2008-01-18 2009-07-18 New Art Advanced Research Technologies Inc. Method of decomposing constituents of a test sample and estimating fluorescence lifetime
JP2010004789A (ja) 2008-06-26 2010-01-14 Nikon Corp 胚観察装置
US8515143B2 (en) 2009-01-09 2013-08-20 Dai Nippon Printing Co., Ltd. Embryo quality evaluation assistance system, embryo quality evaluation assistance apparatus and embryo quality evaluation assistance method
WO2011005974A2 (en) 2009-07-08 2011-01-13 Northwestern University Interpenetrating biomaterial matrices and uses thereof
US8445277B2 (en) 2010-06-24 2013-05-21 The Invention Science Fund I, Llc Rejuvenation or preservation of germ cells
US10222335B2 (en) * 2010-10-27 2019-03-05 The Regents Of The University Of California Phasor method to fluorescence lifetime microscopy to discriminate metabolic state of cells in living tissue
CN103748216B (zh) * 2011-05-31 2018-01-02 尤尼森斯繁殖技术公司 基于卵裂球的卵裂和形态的胚胎质量评估
WO2013006948A1 (en) 2011-07-08 2013-01-17 Robert Casper Methods and compositions for enhancing developmental potential of oocytes and preimplantation embryos

Also Published As

Publication number Publication date
US20180120228A1 (en) 2018-05-03
SG11201505326QA (en) 2015-08-28
US20150346100A1 (en) 2015-12-03
EP2943777A1 (en) 2015-11-18
CA2897530A1 (en) 2014-07-17
JP2016505263A (ja) 2016-02-25
BR112015016375A2 (pt) 2017-07-11
US11579084B2 (en) 2023-02-14
IL239826A0 (en) 2015-08-31
WO2014110008A1 (en) 2014-07-17
KR20150107774A (ko) 2015-09-23
EP2943777A4 (en) 2016-08-24
EP2943777B1 (en) 2018-01-03
US20210239615A1 (en) 2021-08-05
RU2015127205A (ru) 2017-02-15
CN105008900A (zh) 2015-10-28
AU2014205650A1 (en) 2015-07-23

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