BR112015016375A2 - métodos de imagiologia metabólica para avaliação de oócitos e embriões - Google Patents

métodos de imagiologia metabólica para avaliação de oócitos e embriões

Info

Publication number
BR112015016375A2
BR112015016375A2 BR112015016375A BR112015016375A BR112015016375A2 BR 112015016375 A2 BR112015016375 A2 BR 112015016375A2 BR 112015016375 A BR112015016375 A BR 112015016375A BR 112015016375 A BR112015016375 A BR 112015016375A BR 112015016375 A2 BR112015016375 A2 BR 112015016375A2
Authority
BR
Brazil
Prior art keywords
oocyte
imaging methods
oocytes
metabolic imaging
evaluation
Prior art date
Application number
BR112015016375A
Other languages
English (en)
Inventor
Racowsky Catherine
Needleman Daniel
Deng Manqi
Original Assignee
Harvard College
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Brigham & Womens Hospital Inc filed Critical Harvard College
Publication of BR112015016375A2 publication Critical patent/BR112015016375A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6423—Spectral mapping, video display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06193—Secundary in-situ sources, e.g. fluorescent particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation
    • G01N2201/12746—Calibration values determination
    • G01N2201/12761—Precalibration, e.g. for a given series of reagents

Abstract

resumo da patente de invenã§ã£o para: “mã‰todos de imagiologia metabã“lica para avaliaã‡ãƒo de oã“citos e embriã•es”. a presente invenã§ã£o proporciona novos mã©todos in vitro nã£o-invasivos para avaliar a condiã§ã£o metabã³lica de oã³citos e/ou embriãµes atravã©s tã©cnica de fluorescãªncia flim (fluorescence lifetime imaging microscopy) que podem ser utilizados, por exemplo, na avaliaã§ã£o de oã³citos e embriãµes em tecnologias de reproduã§ã£o assistida.
BR112015016375A 2013-01-08 2014-01-07 métodos de imagiologia metabólica para avaliação de oócitos e embriões BR112015016375A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361750061P 2013-01-08 2013-01-08
PCT/US2014/010435 WO2014110008A1 (en) 2013-01-08 2014-01-07 Metabolic imaging methods for assessment of oocytes and embryos

Publications (1)

Publication Number Publication Date
BR112015016375A2 true BR112015016375A2 (pt) 2017-07-11

Family

ID=51167314

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015016375A BR112015016375A2 (pt) 2013-01-08 2014-01-07 métodos de imagiologia metabólica para avaliação de oócitos e embriões

Country Status (13)

Country Link
US (3) US20150346100A1 (pt)
EP (1) EP2943777B1 (pt)
JP (1) JP2016505263A (pt)
KR (1) KR20150107774A (pt)
CN (1) CN105008900A (pt)
AU (1) AU2014205650A1 (pt)
BR (1) BR112015016375A2 (pt)
CA (1) CA2897530A1 (pt)
HK (1) HK1217762A1 (pt)
IL (1) IL239826A0 (pt)
RU (1) RU2015127205A (pt)
SG (1) SG11201505326QA (pt)
WO (1) WO2014110008A1 (pt)

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ES2727868T3 (es) 2011-09-22 2019-10-21 Univ George Washington Sistemas para visualizar el tejido ablacionado
JP5926806B2 (ja) 2011-09-22 2016-05-25 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ アブレーションされた組織を視覚化するシステムと方法
US11096584B2 (en) * 2013-11-14 2021-08-24 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US20150141847A1 (en) 2013-11-20 2015-05-21 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
US9984278B2 (en) 2014-04-16 2018-05-29 President And Fellows Of Harvard College Non-linear imaging systems and methods for assisted reproductive technologies
AU2015343258B2 (en) 2014-11-03 2020-07-16 460Medical, Inc. Systems and methods for lesion assessment
CN107427213B (zh) 2014-11-03 2021-04-16 460医学股份有限公司 用于接触质量的评估的系统和方法
WO2016118557A1 (en) * 2015-01-20 2016-07-28 President And Fellows Of Harvard College Assessing metabolic condition of sperm
CZ307467B6 (cs) * 2015-03-03 2018-09-26 Jihočeská Univerzita V Českých Budějovicích, Fakulta Rybářství A Ochrany Vod, Jihočeské Výzkumné Centrum Akvakultury A Biodiverzity Hydrocenóz, Výzkumný Ústav Rybářský A Hydrobiologický Způsob značení zárodečných buněk, zejména primordiálních gonocytů chrupavčitých ryb
WO2016148905A1 (en) * 2015-03-19 2016-09-22 President And Fellows Of Harvard College Flim for differentiating old and young oocytes
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
CN109415668A (zh) * 2016-06-30 2019-03-01 Esco医用有限公司 一种用于孵育生物材料的设备
US10712272B2 (en) * 2016-09-27 2020-07-14 Trustees Of Tufts College System and method for assessing cellular metabolic activity
US10552957B2 (en) * 2018-03-24 2020-02-04 Dan Nayot Methods and systems for determining quality of an oocyte
JP7414806B2 (ja) * 2018-08-29 2024-01-16 ウィスコンシン アラムニ リサーチ ファンデーション Ｔ細胞を活性化状態によって選別するためのシステムおよび方法
US11386559B2 (en) * 2019-04-03 2022-07-12 The Regents Of The University Of California System and method for tissue viability screening
CN110969616B (zh) * 2019-12-13 2020-10-27 北京推想科技有限公司 评价卵母细胞质量的方法及装置
US20210270810A1 (en) * 2020-02-27 2021-09-02 Intelon Optics, Inc. Contactless inspection of reproductive cellular structures using optical measurement of biomechanical properties
US20220328188A1 (en) * 2021-04-02 2022-10-13 Optiva Fertility, Inc. Artificial intelligence methods for predicting embryo viability based on microscopy methods
US20240026420A1 (en) * 2022-07-12 2024-01-25 Sartorius Bioanalytical Instruments, Inc. FRET Biosensor for Detecting and Reporting NAD+/NADH Ratio Changes

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US5541081A (en) * 1994-03-22 1996-07-30 President And Fellows Of Harvard College Process for assessing oocyte and embryo quality
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WO2013006948A1 (en) 2011-07-08 2013-01-17 Robert Casper Methods and compositions for enhancing developmental potential of oocytes and preimplantation embryos

Also Published As

Publication number Publication date
JP2016505263A (ja) 2016-02-25
RU2015127205A (ru) 2017-02-15
AU2014205650A1 (en) 2015-07-23
EP2943777B1 (en) 2018-01-03
WO2014110008A1 (en) 2014-07-17
US11579084B2 (en) 2023-02-14
EP2943777A1 (en) 2015-11-18
US20210239615A1 (en) 2021-08-05
CA2897530A1 (en) 2014-07-17
IL239826A0 (en) 2015-08-31
HK1217762A1 (zh) 2017-01-20
KR20150107774A (ko) 2015-09-23
US20180120228A1 (en) 2018-05-03
CN105008900A (zh) 2015-10-28
EP2943777A4 (en) 2016-08-24
SG11201505326QA (en) 2015-08-28
US20150346100A1 (en) 2015-12-03

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements