CN102229589A - 作为金属蛋白酶抑制剂的n-{4′-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 - Google Patents
作为金属蛋白酶抑制剂的n-{4′-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 Download PDFInfo
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- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
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- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301922A SE0301922D0 (sv) | 2003-06-27 | 2003-06-27 | Novel compounds |
| SE0301922-1 | 2003-06-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2004800182447A Division CN1812974B (zh) | 2003-06-27 | 2004-06-23 | 作为金属蛋白酶抑制剂的n-{‘4-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102229589A true CN102229589A (zh) | 2011-11-02 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110103041XA Pending CN102229589A (zh) | 2003-06-27 | 2004-06-23 | 作为金属蛋白酶抑制剂的n-{4′-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 |
| CN2004800182447A Expired - Fee Related CN1812974B (zh) | 2003-06-27 | 2004-06-23 | 作为金属蛋白酶抑制剂的n-{‘4-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2004800182447A Expired - Fee Related CN1812974B (zh) | 2003-06-27 | 2004-06-23 | 作为金属蛋白酶抑制剂的n-{‘4-取代的哌嗪-1-磺酰基甲基烷基}-n-羟基甲酰胺化合物 |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US7485644B2 (https=) |
| EP (1) | EP1644340B1 (https=) |
| JP (1) | JP4701167B2 (https=) |
| KR (1) | KR20060026440A (https=) |
| CN (2) | CN102229589A (https=) |
| AR (1) | AR044931A1 (https=) |
| AT (1) | ATE414063T1 (https=) |
| AU (1) | AU2004251104B2 (https=) |
| BR (1) | BRPI0411929A (https=) |
| CA (1) | CA2529468A1 (https=) |
| CO (1) | CO5650254A2 (https=) |
| CY (1) | CY1108757T1 (https=) |
| DE (1) | DE602004017733D1 (https=) |
| DK (1) | DK1644340T3 (https=) |
| ES (1) | ES2315675T3 (https=) |
| HR (1) | HRP20090009T3 (https=) |
| IL (1) | IL172615A0 (https=) |
| IS (1) | IS8257A (https=) |
| MX (1) | MXPA05013460A (https=) |
| MY (1) | MY138680A (https=) |
| NO (1) | NO20060444L (https=) |
| NZ (1) | NZ544208A (https=) |
| PL (1) | PL1644340T3 (https=) |
| PT (1) | PT1644340E (https=) |
| RU (1) | RU2351595C2 (https=) |
| SA (1) | SA04250224B1 (https=) |
| SE (1) | SE0301922D0 (https=) |
| SI (1) | SI1644340T1 (https=) |
| TW (1) | TW200524898A (https=) |
| UA (1) | UA81491C2 (https=) |
| UY (1) | UY28387A1 (https=) |
| WO (1) | WO2005000822A1 (https=) |
| ZA (1) | ZA200510458B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0427403D0 (en) | 2004-12-15 | 2005-01-19 | Astrazeneca Ab | Novel compounds I |
| ZA200803327B (en) * | 2005-10-26 | 2009-09-30 | Serono Lab | Sulfonamide derivatives and use thereof for the modulation of metalloproteinases |
| CN101007794B (zh) * | 2006-01-26 | 2010-09-01 | 中国科学院上海药物研究所 | N,n'-二取代哌嗪类衍生物及其制备方法、药物组合物和用途 |
| WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
| DK2597084T3 (en) * | 2010-07-08 | 2016-08-15 | Kaken Pharma Co Ltd | N-HYDROXYFORMAMIDE DERIVATIVE AND MEDICINAL CONTAINING SAME |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL200418B1 (pl) * | 1998-01-30 | 2009-01-30 | Darwin Discovery Ltd | Pochodna N-hydroksyformamidu, zawierający ją środek farmaceutyczny i jej zastosowanie |
| GB9919776D0 (en) * | 1998-08-31 | 1999-10-27 | Zeneca Ltd | Compoujnds |
| EP1187811B1 (en) * | 1999-06-04 | 2007-03-07 | AstraZeneca AB | Inhibitors of metalloproteinases |
| PL365909A1 (en) * | 2000-02-21 | 2005-01-10 | Astrazeneca Ab | Piperidine- and piperazine substituted n-hydroxyformamides as inhibitors of metalloproteinases |
| GB0119472D0 (en) | 2001-08-09 | 2001-10-03 | Astrazeneca Ab | Compounds |
| MXPA04010555A (es) * | 2002-04-25 | 2005-02-17 | Pharmacia Corp | Acidos piperidinil- y piperazinil-sulfonilmetil hidroxamicos y su uso como inhibidores de proteasa. |
| ATE411303T1 (de) * | 2003-06-19 | 2008-10-15 | Ucb Pharma Sa | Hydroxamatsulfonamide als inhibitoren von cd23- shedding |
-
2003
- 2003-06-27 SE SE0301922A patent/SE0301922D0/xx unknown
-
2004
- 2004-06-23 PL PL04743053T patent/PL1644340T3/pl unknown
- 2004-06-23 JP JP2006516467A patent/JP4701167B2/ja not_active Expired - Fee Related
- 2004-06-23 HR HR20090009T patent/HRP20090009T3/xx unknown
- 2004-06-23 AU AU2004251104A patent/AU2004251104B2/en not_active Ceased
- 2004-06-23 US US10/561,747 patent/US7485644B2/en not_active Expired - Fee Related
- 2004-06-23 DK DK04743053T patent/DK1644340T3/da active
- 2004-06-23 BR BRPI0411929-0A patent/BRPI0411929A/pt not_active IP Right Cessation
- 2004-06-23 WO PCT/GB2004/002702 patent/WO2005000822A1/en not_active Ceased
- 2004-06-23 KR KR1020057024709A patent/KR20060026440A/ko not_active Abandoned
- 2004-06-23 ES ES04743053T patent/ES2315675T3/es not_active Expired - Lifetime
- 2004-06-23 EP EP04743053A patent/EP1644340B1/en not_active Expired - Lifetime
- 2004-06-23 AT AT04743053T patent/ATE414063T1/de active
- 2004-06-23 PT PT04743053T patent/PT1644340E/pt unknown
- 2004-06-23 NZ NZ544208A patent/NZ544208A/en unknown
- 2004-06-23 UA UAA200511723A patent/UA81491C2/uk unknown
- 2004-06-23 CA CA002529468A patent/CA2529468A1/en not_active Abandoned
- 2004-06-23 DE DE602004017733T patent/DE602004017733D1/de not_active Expired - Lifetime
- 2004-06-23 SI SI200430979T patent/SI1644340T1/sl unknown
- 2004-06-23 CN CN201110103041XA patent/CN102229589A/zh active Pending
- 2004-06-23 MX MXPA05013460A patent/MXPA05013460A/es active IP Right Grant
- 2004-06-23 RU RU2005141058/04A patent/RU2351595C2/ru not_active IP Right Cessation
- 2004-06-23 CN CN2004800182447A patent/CN1812974B/zh not_active Expired - Fee Related
- 2004-06-25 UY UY28387A patent/UY28387A1/es unknown
- 2004-06-25 MY MYPI20042517A patent/MY138680A/en unknown
- 2004-06-25 TW TW093118692A patent/TW200524898A/zh unknown
- 2004-06-25 AR ARP040102258A patent/AR044931A1/es not_active Application Discontinuation
- 2004-07-14 SA SA04250224A patent/SA04250224B1/ar unknown
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2005
- 2005-12-15 IL IL172615A patent/IL172615A0/en unknown
- 2005-12-22 ZA ZA200510458A patent/ZA200510458B/xx unknown
- 2005-12-27 CO CO05130352A patent/CO5650254A2/es not_active Application Discontinuation
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2006
- 2006-01-23 IS IS8257A patent/IS8257A/is unknown
- 2006-01-27 NO NO20060444A patent/NO20060444L/no not_active Application Discontinuation
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2009
- 2009-01-19 CY CY20091100064T patent/CY1108757T1/el unknown
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