CN102203606A - 生物标记物 - Google Patents

生物标记物 Download PDF

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Publication number
CN102203606A
CN102203606A CN200980143296XA CN200980143296A CN102203606A CN 102203606 A CN102203606 A CN 102203606A CN 200980143296X A CN200980143296X A CN 200980143296XA CN 200980143296 A CN200980143296 A CN 200980143296A CN 102203606 A CN102203606 A CN 102203606A
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CN
China
Prior art keywords
vegfb
levels
patient
thbs1
pgf
Prior art date
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Pending
Application number
CN200980143296XA
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English (en)
Chinese (zh)
Inventor
伊万·德沃
丹尼尔·R·瓦格纳
弗朗西斯科·阿苏亚加
梅兰尼·沃索特
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Centre de Recherche Public de la Sante
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Centre de Recherche Public de la Sante
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Publication date
Application filed by Centre de Recherche Public de la Sante filed Critical Centre de Recherche Public de la Sante
Publication of CN102203606A publication Critical patent/CN102203606A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Primary Health Care (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200980143296XA 2008-10-30 2009-10-30 生物标记物 Pending CN102203606A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10964908P 2008-10-30 2008-10-30
US61/109,649 2008-10-30
PCT/EP2009/064410 WO2010049538A1 (en) 2008-10-30 2009-10-30 Biomarkers

Publications (1)

Publication Number Publication Date
CN102203606A true CN102203606A (zh) 2011-09-28

Family

ID=41528764

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980143296XA Pending CN102203606A (zh) 2008-10-30 2009-10-30 生物标记物

Country Status (9)

Country Link
US (2) US20110294683A1 (enExample)
EP (1) EP2362942B1 (enExample)
JP (1) JP5749171B2 (enExample)
CN (1) CN102203606A (enExample)
BR (1) BRPI0920069A8 (enExample)
CA (1) CA2741117A1 (enExample)
ES (1) ES2640900T3 (enExample)
RU (1) RU2545757C2 (enExample)
WO (1) WO2010049538A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105659095A (zh) * 2013-08-26 2016-06-08 豪夫迈·罗氏有限公司 在心力衰竭中用于抑制素治疗分层的标记物

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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MX355020B (es) 2010-07-09 2018-04-02 Somalogic Inc Biomarcadores de cancer de pulmon y usos de los mismos.
JP5931874B2 (ja) 2010-08-13 2016-06-08 ソマロジック・インコーポレーテッド 膵癌バイオマーカーおよびその使用
EP2592422A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
EP2592423A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment
JP2014207883A (ja) * 2013-03-27 2014-11-06 国立大学法人岡山大学 がん幹細胞及びその用途
CN105451758A (zh) * 2013-05-31 2016-03-30 科比欧尔斯公司 用于心力衰竭的预防或治疗的人plgf-2
CN103487586B (zh) * 2013-09-04 2015-07-15 石家庄洹众生物科技有限公司 一种定量检测可溶性生长刺激表达蛋白2的试验装置
PL228091B1 (pl) * 2014-02-12 2018-02-28 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Zestaw biomarkerów transkryptomicznych do zastosowania w stratyfikacji indywidualnego ryzyka rozwoju pozawałowej niewydolnosci serca, sposób diagnozowania ryzyka wystapienia u pacjenta pozawałowej niewydolnosci serca i zastosowanie biomarkerów do diagnostyki in vitro
US10041120B2 (en) 2014-05-28 2018-08-07 Scripps Health Predictive analysis for myocardial infarction
CN105243294B (zh) * 2015-09-18 2017-06-09 淮南师范学院 一种用于预测癌症病人预后相关的蛋白质对的方法
RU2634375C2 (ru) * 2016-04-18 2017-10-26 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт кардиологии" Способ предупреждения постинфарктного ремоделирования сердца в эксперименте
JP7448310B2 (ja) * 2016-07-06 2024-03-12 ガーダント ヘルス， インコーポレイテッド セルフリー核酸のフラグメントームプロファイリングのための方法
DE102017116204B4 (de) * 2017-07-18 2024-06-27 Universität Rostock Verfahren zur Vorhersage der Antwort auf die kardiovaskuläre Regeneration
US11708600B2 (en) * 2017-10-05 2023-07-25 Decode Health, Inc. Long non-coding RNA gene expression signatures in disease diagnosis
CN114449944A (zh) * 2019-09-30 2022-05-06 豪夫迈·罗氏有限公司 疾病状态预测
JP7489059B2 (ja) * 2020-04-21 2024-05-23 国立大学法人横浜国立大学 画像生成装置、表示装置、画像生成方法、提示方法およびプログラム
US11854675B1 (en) 2022-10-11 2023-12-26 Flatiron Health, Inc. Machine learning extraction of clinical variable values for subjects from clinical record data
US11915807B1 (en) * 2022-10-11 2024-02-27 Flatiron Health, Inc. Machine learning extraction of clinical variable values for subjects from clinical record data

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1251901A (zh) * 1999-11-09 2000-05-03 赵永同 肿瘤早期检测评估试剂盒及其制备工艺
CN1260492A (zh) * 1999-11-09 2000-07-19 赵永同 肿瘤预后评估试剂盒及其制备工艺
WO2003020120A2 (en) * 2001-09-04 2003-03-13 Vitivity, Inc. Diagnosis and treatment of vascular disease
CN1420987A (zh) * 1999-11-16 2003-05-28 杰南技术公司 用于vegf的elisa
CN1441849A (zh) * 2000-05-17 2003-09-10 路德维格癌症研究所 检测肿瘤细胞的存在及筛选抗肿瘤剂的方法
CN1568425A (zh) * 2001-08-13 2005-01-19 遗传学发展股份有限公司 选择人类肿瘤最佳疗法的分子诊断和计算机决策辅助系统
WO2006001888A2 (en) * 2004-04-16 2006-01-05 Acuity Pharmaceuticals Inc Compositions and methods for inhibiting angiogenesis
WO2007044534A2 (en) * 2005-10-06 2007-04-19 Trophogen, Inc. Vegf analogs and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
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NZ513780A (en) * 1999-03-03 2001-09-28 Ludwig Inst Cancer Res Heart abnormalities in vascular endothelial growth factor B (VEGF-B) deficient animals and methods relating to these heart abnormalities
US7709450B2 (en) * 2001-06-20 2010-05-04 Ludwig Institute For Cancer Research Stimulation of vascularization with VEGF-B-186
US7435419B2 (en) * 2002-07-19 2008-10-14 Beth Israel Deaconess Medical Center Methods of diagnosing and treating pre-eclampsia or eclampsia
CA2509063C (en) * 2002-11-16 2010-11-02 Dade Behring Marburg Gmbh Scd40l and placental growth factor (plgf) as biochemical marker combinations in cardiovascular diseases
JP4949038B2 (ja) * 2003-12-01 2012-06-06 ダコ デンマーク アクティーゼルスカブ 免疫組織化学的検出のための方法および組成物
US20070037232A1 (en) * 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1251901A (zh) * 1999-11-09 2000-05-03 赵永同 肿瘤早期检测评估试剂盒及其制备工艺
CN1260492A (zh) * 1999-11-09 2000-07-19 赵永同 肿瘤预后评估试剂盒及其制备工艺
CN1420987A (zh) * 1999-11-16 2003-05-28 杰南技术公司 用于vegf的elisa
CN1441849A (zh) * 2000-05-17 2003-09-10 路德维格癌症研究所 检测肿瘤细胞的存在及筛选抗肿瘤剂的方法
CN1568425A (zh) * 2001-08-13 2005-01-19 遗传学发展股份有限公司 选择人类肿瘤最佳疗法的分子诊断和计算机决策辅助系统
WO2003020120A2 (en) * 2001-09-04 2003-03-13 Vitivity, Inc. Diagnosis and treatment of vascular disease
WO2006001888A2 (en) * 2004-04-16 2006-01-05 Acuity Pharmaceuticals Inc Compositions and methods for inhibiting angiogenesis
WO2007044534A2 (en) * 2005-10-06 2007-04-19 Trophogen, Inc. Vegf analogs and methods of use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105659095A (zh) * 2013-08-26 2016-06-08 豪夫迈·罗氏有限公司 在心力衰竭中用于抑制素治疗分层的标记物

Also Published As

Publication number Publication date
EP2362942A1 (en) 2011-09-07
CA2741117A1 (en) 2010-05-06
RU2545757C2 (ru) 2015-04-10
RU2011121613A (ru) 2012-12-10
EP2362942B1 (en) 2017-06-21
JP5749171B2 (ja) 2015-07-15
BRPI0920069A8 (pt) 2017-10-03
ES2640900T3 (es) 2017-11-07
US20110294683A1 (en) 2011-12-01
WO2010049538A1 (en) 2010-05-06
JP2012507026A (ja) 2012-03-22
US20160188835A1 (en) 2016-06-30
BRPI0920069A2 (pt) 2017-06-06

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Application publication date: 20110928