CN102203126A - 用于制备纯化的多肽组合物的方法 - Google Patents

用于制备纯化的多肽组合物的方法 Download PDF

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Publication number
CN102203126A
CN102203126A CN2009801425171A CN200980142517A CN102203126A CN 102203126 A CN102203126 A CN 102203126A CN 2009801425171 A CN2009801425171 A CN 2009801425171A CN 200980142517 A CN200980142517 A CN 200980142517A CN 102203126 A CN102203126 A CN 102203126A
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Prior art keywords
amino acid
composition
alpha
peptide
peptidomimetic macrocycle
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Pending
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CN2009801425171A
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English (en)
Chinese (zh)
Inventor
H·M·纳什
M·雅丹扎
C·雷泰瑟
川端纪之
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Rein Therapeutics Inc
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Aileron Therapeutics Inc
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Priority to CN201510159021.2A priority Critical patent/CN104961795A/zh
Publication of CN102203126A publication Critical patent/CN102203126A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Molecular Biology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Obesity (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
CN2009801425171A 2008-09-22 2009-09-22 用于制备纯化的多肽组合物的方法 Pending CN102203126A (zh)

Priority Applications (1)

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US9909908P 2008-09-22 2008-09-22
US61/099,099 2008-09-22
PCT/US2009/057931 WO2010034032A2 (en) 2008-09-22 2009-09-22 Methods for preparing purified polypeptide compositions

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US (5) US9206223B2 (enExample)
EP (2) EP2342221B1 (enExample)
JP (5) JP2012503025A (enExample)
CN (2) CN102203126A (enExample)
AU (1) AU2009294875C1 (enExample)
BR (1) BRPI0918838A2 (enExample)
CA (1) CA2737921C (enExample)
IL (2) IL211837A (enExample)
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CN112245565A (zh) * 2014-09-24 2021-01-22 艾瑞朗医疗公司 拟肽大环化合物及其用途
CN112500466A (zh) * 2012-02-15 2021-03-16 艾瑞朗医疗公司 拟肽大环化合物

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CN105792851B (zh) 2013-09-13 2023-10-10 斯克利普斯研究所 修饰的治疗剂及其组合物
MX378668B (es) * 2013-10-28 2025-03-10 Naurex Inc Profarmacos y moduladores de receptores nmda, sales y usos de estos.
AU2014364589B2 (en) 2013-12-18 2020-02-27 The California Institute For Biomedical Research Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
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