AU6162996A - Synthesis of conformationally restricted amino acids, peptides and peptidomimetics by catalytic ring closing metathesis - Google Patents

Synthesis of conformationally restricted amino acids, peptides and peptidomimetics by catalytic ring closing metathesis

Info

Publication number
AU6162996A
AU6162996A AU61629/96A AU6162996A AU6162996A AU 6162996 A AU6162996 A AU 6162996A AU 61629/96 A AU61629/96 A AU 61629/96A AU 6162996 A AU6162996 A AU 6162996A AU 6162996 A AU6162996 A AU 6162996A
Authority
AU
Australia
Prior art keywords
peptidomimetics
peptides
synthesis
amino acids
ring closing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61629/96A
Inventor
Helen E. Blackwell
Robert H. Grubbs
J. Scott Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Publication of AU6162996A publication Critical patent/AU6162996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
AU61629/96A 1996-01-17 1996-06-07 Synthesis of conformationally restricted amino acids, peptides and peptidomimetics by catalytic ring closing metathesis Abandoned AU6162996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1017096P 1996-01-17 1996-01-17
US010170 1996-01-17
PCT/US1996/009591 WO1997026002A1 (en) 1996-01-17 1996-06-07 Synthesis of conformationally restricted amino acids, peptides and peptidomimetics by catalytic ring closing metathesis

Publications (1)

Publication Number Publication Date
AU6162996A true AU6162996A (en) 1997-08-11

Family

ID=21744291

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61629/96A Abandoned AU6162996A (en) 1996-01-17 1996-06-07 Synthesis of conformationally restricted amino acids, peptides and peptidomimetics by catalytic ring closing metathesis

Country Status (3)

Country Link
EP (1) EP0880357A4 (en)
AU (1) AU6162996A (en)
WO (1) WO1997026002A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
US6582726B1 (en) * 2000-06-21 2003-06-24 Smithkline Beecham Corporation Cross linked solid supports for solid phase synthesis
WO2002016552A2 (en) * 2000-08-19 2002-02-28 University Of Florida Functionalized polymers
WO2008048121A2 (en) * 2006-10-18 2008-04-24 Lincoln University Macrocyclic cysteine protease inhibitors and compositions thereof
KR101623985B1 (en) 2007-03-28 2016-05-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Stitched polypeptides
CN102203126A (en) * 2008-09-22 2011-09-28 爱勒让治疗公司 Methods for preparing purified polypeptide compositions
PT2603600T (en) 2010-08-13 2019-02-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
CN104039342A (en) 2011-10-18 2014-09-10 爱勒让治疗公司 Peptidomimetic macrocyles
EP2822572B1 (en) 2012-02-15 2020-06-10 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
BR112015009470A2 (en) 2012-11-01 2019-12-17 Aileron Therapeutics Inc disubstituted amino acids and their methods of preparation and use
BR112015022872A2 (en) * 2013-03-13 2017-11-07 Harvard College stapled and stitched polypeptides, their use, their method of preparation, their composition and amino acid
CA2915354A1 (en) 2013-06-14 2014-12-18 President And Fellows Of Harvard College Stabilized polypeptide insulin receptor modulators
US10533039B2 (en) 2014-05-21 2020-01-14 President And Fellows Of Harvard College Ras inhibitory peptides and uses thereof
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
EP3197477A4 (en) 2014-09-24 2018-07-04 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
US10253067B2 (en) 2015-03-20 2019-04-09 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2020023502A1 (en) 2018-07-23 2020-01-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US11584956B2 (en) * 2018-12-21 2023-02-21 Microsoft Technology Licensing, Llc Selectively controllable cleavable linkers

Also Published As

Publication number Publication date
EP0880357A1 (en) 1998-12-02
EP0880357A4 (en) 1999-05-12
WO1997026002A1 (en) 1997-07-24

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