CN102178062A - Application of glyceroltriacetate as feed acidating agent - Google Patents
Application of glyceroltriacetate as feed acidating agent Download PDFInfo
- Publication number
- CN102178062A CN102178062A CN2011101281456A CN201110128145A CN102178062A CN 102178062 A CN102178062 A CN 102178062A CN 2011101281456 A CN2011101281456 A CN 2011101281456A CN 201110128145 A CN201110128145 A CN 201110128145A CN 102178062 A CN102178062 A CN 102178062A
- Authority
- CN
- China
- Prior art keywords
- feed
- glyceroltriacetate
- animal
- glyceryl triacetate
- acidulant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Fodder In General (AREA)
Abstract
The invention relates to an application of glyceroltriacetate as a feed acidating agent. The glyceroltriacetate has the characteristics that the molecular formula is C9H14O6 and the molecular weight is 218.20. The invention has the advantages that, on the basis of the characteristic that glyceroltriacetate is slowly decomposed in digestive tract of an animal, the pH value of a gastrointestinal tract is reduced, noxious bacteria in the gastrointestinal tract are reduced, propagation of beneficial bacteria is promoted, and the effects of acidificating the gastrointestinal tract and adjusting flora are achieved, thus the health of the animal is promoted.
Description
Technical field
The present invention relates to the purposes of glyceryl triacetate, relate in particular to the purposes in animal feed acidulant field.
Background technology
Development along with modern animal husbandry and feed industry, the drug resistance problem of current pathogen has been subjected to extensive concern, use the effect of this type of infection of antibiotic therapy unsatisfactory, and fodder acidulant is just more and more paid attention to by people as the environment protection additive of a kind of noresidue, the no resistance to the action of a drug, nonhazardous.Studies show that, acidulant enters livestock and poultry or the aquatic animal intestines and stomach pass through to reduce the pH value later on, can promote the growth and breeding of beneficial bacteriums such as lactic acid bacteria, change the living environment of pernicious bacteria simultaneously, can suppress or direct kill harmful flora such as Escherichia coli, salmonella, staphylococcus and clostridium etc.Acidulant more and more is subjected to vast feed worker and culturist's attention as a kind ofly can effectively improving feed and alimentary canal acidity, keep animal gastrointestinal tract microbial ecosystem balance, alleviating a kind of additive of stress of baby pigs caused ablaction.
At present, there is following shortcoming in acidulant: no matter be single acid or compound acid, mostly the form with free acid exists, mainly absorbed rapidly at stomach, can't be in well effect of the rear end of gastral latter half of particularly enteron aisle performance, and the digestion of food and absorption are mainly carried out at small intestine, and pathogenic microorganism also mainly is positioned at the enteron aisle back segment, so the direct acidulant that adds can not play the effect of good enteron aisle acidifying and flora adjusting.So, it is more obvious to it is generally acknowledged that acidulant is mainly used in the piglet effect, increase along with the piglet body weight, external source adds sour effect and weakens, this may be mainly relevant in the stomach effect with selected acid, if targetedly with organic acid through bag by other processing, its major part do not discharged under one's belt and directly enter small intestine, can bring into play better effect in theory.
In order to make the acidulant arrival enteron aisle and the enteron aisle rear end of effective dose, the mode that adopts bag quilt or part to wrap quilt mostly solves this problem at present.By the bag quilt, can slow down the rate of release of acid, make the non-dissociated acid of part enter small intestine simultaneously with chyme, have an effect at the alimentary canal latter half.Can arrive intestine of young pigs performance acidization such as microcapsule-type slowly-releasing compound acidulant, but bag is increased the use cost of acidulant, thereby has limited the popularization of acidulant.
Hydrochlorate is owing to have the part slow-release function, prevented that to a certain extent the nutritional labeling in acid and equipment and the feed from reacting, can reduce the rate of release of acid in stomach and enteron aisle again, make its effect can last till enteron aisle always, but be difficult to guarantee to have the acid dimension of sufficient amount continuous to gastral terminal generation effect.Simultaneously, salify need be done certain adjustment to the addition of some nutrient in the feed with it, can make the content overproof of calcium in the feed such as adding calcium formate or other organic acid calcium salts, and cause calcium phosphorus ration seriously to be lacked of proper care.These defectives have constituted restriction to the application of acidulant equally.
Therefore, need to seek better fodder acidulant, be used for promoting animal stomach and intestinal microecology balance, prevention animal intestinal bacteriosis uses antibiotic requirement with the breed efficient that improves animal with reducing.
Under the natural conditions, acetate, mainly generated through the anaerobic bacteria glycolysis in colonic lumen by indigestion starch, fiber polysaccharide etc. in the diet, it not only provides main energy supply for mucous membrane of colon, can also safeguard the integrality of intestinal epithelial cell and the secreting function of goblet cell; Can also reduce the generation of proinflammatory factor, help the reparation of mucosal inflammation; Can also suppress some tumor cell proliferation, and inducing tumor cell differentiation and apoptosis; And, animal intestinal inside, acetate can suppress Escherichia coli, pathogenic entero becterias such as salmonella, and to the inhibitory action of beneficial bacterias such as lactic acid bacteria a little less than. acetate belongs to country and allows the fodder acidulant that adds, but has strong impulse comparatively and for the corrosivity of equipment, directly add, use salify or coated back, has foregoing various shortcoming equally, and mainly be absorbed at gastral leading portions such as stomach, can't enter small intestine, position such as colon particularly can not effectively reduce the pH value of alimentary canal back segment, can not play the effect of good adjusting gut flora.
Acetate is called glyceryl triacetate, molecular formula after by glycerine esterification: C
9H
14O
6, molecular mass: 218.20, structural formula is:
Existing file does not retrieve the technical scheme that glyceryl triacetate is used as the animal feed acidulant, and glyceryl triacetate is used as plasticizer and perfume fixative, printing ink solvent at present, also is used for synthesizing of medicine and dyestuff.
Summary of the invention
The purpose of this invention is to provide a kind of fodder acidulant.
Technical problem to be solved by this invention provides the new purposes of glyceryl triacetate, promptly as the new application of fodder acidulant.
The technical solution adopted for the present invention to solve the technical problems.Glyceryl triacetate meets molecular formula as the application of fodder acidulant: C
9H
14O
6, molecular mass: 218.20, structural formula is
Glyceryl triacetate enters after the alimentary canal, at first needs to be decomposed into glycerine and acetate by the secreted lipase of alimentary canal, can be absorbed then, and lipase is mainly derived from pancreas, and be stomach and small intestine secondly.Therefore, glyceryl triacetate is slowly decomposed in alimentary canal, and acetate is slowly discharged.Glyceryl triacetate has following characteristics, and the first, can not produce bad property accumulated and specific reaction in vivo; Therefore the second, with respect to free acids such as acetate or acetates, the decomposable process of glyceryl triacetate is chemistry or biological slow-released process, can arrive enteron aisle, and especially gastral rear end such as colon plays a role, and its active ingredient that plays a role is acetate.
Glyceryl triacetate of the present invention is realized by the following method as the using method of fodder acidulant:
Glyceryl triacetate, addition are the 0.01%-3.0% of feed gross weight, and preferred 0.2%-1.0% makes an addition in the feed after composite separately or with other feed addictive; Perhaps will add again after the absorption of this product suppressed by vector.
Glyceryl triacetate of the present invention is as the application of fodder acidulant, and application is the livestock and poultry and the aquatic animal of artificial feeding.
The advantage that the present invention had is:
1. glyceryl triacetate, under action of lipase, catabolite is acetate and glycerine in vivo, the two is normal metabolin in the animal body, and is without any side effects to human and animal's body.
2. glyceryl triacetate decomposes in animal alimentary canal as fodder acidulant, slowly releases acetate; it can reduce the acid-base value of stomach and enteron aisle; effectively reduce the harmful bacteria of enteron aisle, promote the breeding of beneficial bacteria, thereby promote the growth of animal and the health that watches for animals.
3. be neutral before being decomposed by lipase, not producing stimulates and corrosiveness.
With respect to acidulants such as acetate and acetates, glyceryl triacetate also has following advantage as fodder acidulant:
Slowly discharge acetate, therefore can significantly not change pH value in the stomach and releasing stimulus and uncomfortable.
Site of action until colon, thereby plays whole enteron aisle acidifying and regulates the flora effect from the stomach to the enteron aisle.
Avoid to nutriment in the feed (particularly premix), as the destruction of vitamin, mineral matter.
Avoid the acid corrosion of feed-processing equipment is damaged.
Slowly discharge acetate, little to the injury of skin and mucous membrane.
Acetate by glycerine esterification after, have aromatic odor, have the palatability ability of improving feed.
So glyceryl triacetate is to substitute the important substance that antibiotic uses in the animal-breeding process, be the antibiotic substitute of desirable environment amenable noresidue.
The specific embodiment
Embodiment 1:
Pig farm oneself is joined feed and is tested, and 9 of diarrhoea sows are cultivated to observe the fecal bacteria ratio with Escherichia coli and lactic acid bacteria isolation medium viable bacteria and to change, and add the feed of glyceryl triacetate 0.2%, use continuously three days.The result is as follows: 6 stop diarrhoea, and efficient is 66.7%; The second, average Escherichia coli and lactic acid bacteria ratio are 6: 1 before using, and use back Escherichia coli and lactic acid bacteria ratio to be reduced to 1.6: 1.
Embodiment 2:
100 ablactation of feed lot piglet is divided into two groups, 50 every group, add glyceryl triacetate 1.0% in one group of feed, and another group in contrast, cultivates to observe the fecal bacteria ratio with Escherichia coli and lactic acid bacteria isolation medium viable bacteria to change.
Observed result after one week, the result is as follows:
The first, 39 example diarrhoea take place in control group, and the interpolation group has only 8 examples.
The second, average Escherichia coli of control group and lactic acid bacteria ratio average out to are 0.86: 1 before using, experimental group Escherichia coli and lactic acid bacteria ratio average out to 0.9: 1, the two basically identical.After testing a week, control group Escherichia coli and lactic acid bacteria ratio average out to 2.25: 1, experimental group is average out to 0.75: 1 then.
Claims (2)
1. the purposes of an organic compound, it is characterized in that: glyceryl triacetate is used for the application of fodder acidulant, using method be addition according to feed gross weight meter, be 0.01%-3.0%, directly glyceryl triacetate is made an addition in the feed; Or add again after composite with other feed addictive; Or will add again after the absorption of this product suppressed by vector.
2. the purposes of a kind of organic compound according to claim 1 is characterized in that described addition is 0.2%-1.0%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101281456A CN102178062A (en) | 2011-05-17 | 2011-05-17 | Application of glyceroltriacetate as feed acidating agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101281456A CN102178062A (en) | 2011-05-17 | 2011-05-17 | Application of glyceroltriacetate as feed acidating agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102178062A true CN102178062A (en) | 2011-09-14 |
Family
ID=44564478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011101281456A Pending CN102178062A (en) | 2011-05-17 | 2011-05-17 | Application of glyceroltriacetate as feed acidating agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102178062A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105685511A (en) * | 2016-03-01 | 2016-06-22 | 湖南晶天科技实业有限公司 | Application of acetoglyceride in feed for young animals as energy supply substances and acetoglyceride compound feed additive |
| CN111748500A (en) * | 2020-07-23 | 2020-10-09 | 甘肃金色阳光农牧科技有限公司 | Fermentation seed liquid for fermenting soybean meal, slow-speed fermentation soybean meal prepared from fermentation seed liquid and preparation method of slow-speed fermentation soybean meal |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5234277A (en) * | 1975-09-09 | 1977-03-16 | Asahi Denka Kogyo Kk | Aising method for a beef cattle |
| EP1224870A1 (en) * | 2001-01-23 | 2002-07-24 | Xeris | Use of tributyrin in animal feed and corresponding feed additive |
| CN1513347A (en) * | 2003-07-24 | 2004-07-21 | 侯永清 | Application os glycerin tributyrate as feed additive |
-
2011
- 2011-05-17 CN CN2011101281456A patent/CN102178062A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5234277A (en) * | 1975-09-09 | 1977-03-16 | Asahi Denka Kogyo Kk | Aising method for a beef cattle |
| EP1224870A1 (en) * | 2001-01-23 | 2002-07-24 | Xeris | Use of tributyrin in animal feed and corresponding feed additive |
| CN1513347A (en) * | 2003-07-24 | 2004-07-21 | 侯永清 | Application os glycerin tributyrate as feed additive |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105685511A (en) * | 2016-03-01 | 2016-06-22 | 湖南晶天科技实业有限公司 | Application of acetoglyceride in feed for young animals as energy supply substances and acetoglyceride compound feed additive |
| CN111748500A (en) * | 2020-07-23 | 2020-10-09 | 甘肃金色阳光农牧科技有限公司 | Fermentation seed liquid for fermenting soybean meal, slow-speed fermentation soybean meal prepared from fermentation seed liquid and preparation method of slow-speed fermentation soybean meal |
| CN111748500B (en) * | 2020-07-23 | 2023-08-25 | 甘肃金色阳光农牧科技有限公司 | Fermented seed liquid for fermented soybean meal, retarded fermented soybean meal prepared from fermented seed liquid and preparation method of retarded fermented soybean meal |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104206859B (en) | Antibiotic-free feed for fattening pigs and preparation method thereof | |
| CN102987093A (en) | Feeding plant essential oil additive as well as preparation and application of additive | |
| JP2001500364A (en) | Feed | |
| CN109770078A (en) | A kind of feed addictive preventing nursing period calf diarrhea and its application method | |
| JP2009057284A (en) | Microbial preparation for reducing greenhouse effect gas excreted from livestock or fowl | |
| CN110892947A (en) | Compound acidifier for poultry and preparation method and application thereof | |
| CN108813123A (en) | It is a kind of improve intestine of young pigs health enteral nutrition packet and application | |
| CN103392922A (en) | Compound feed additive capable of improving health level of animal | |
| CN102204633A (en) | Application of glyceryl tripropionate as feed acidifier | |
| CN101213951B (en) | Emission reduction drying type cultivation method for producing non-antibiotics pork | |
| CN103082095B (en) | Application of triglyceryl lactate as feed acidifier | |
| CN105941870A (en) | Nanometer montmorillonite feed additive compound for detoxifying and diarrhea prevention of livestock and poultry | |
| CN103005204B (en) | Nutritional anti-stress bioremediation composition for pigs and preparation method thereof | |
| EP3288391B1 (en) | Feed supplement additive | |
| RU2517745C2 (en) | Method for growing broiler chickens | |
| CN102461732A (en) | Composition containing butyric acid bacteria | |
| CN102178062A (en) | Application of glyceroltriacetate as feed acidating agent | |
| WO2001028551A9 (en) | Agents for promoting fattening of animals and method of promoting fattening | |
| Boamah et al. | Application of low molecular weight chitosan in animal nutrition, husbandry, and health: A review | |
| AU2022285032A1 (en) | Use of furan formic acid compound in preparing animal feed additive | |
| JP2011182748A (en) | Feed for livestock or poultry | |
| CN114365794A (en) | Functional multi-vitamin proteingrass and feeding method thereof | |
| CN102204634A (en) | Application of triformic acid glyceride as feed acidifier | |
| CN105685529A (en) | Feed additive for preventing tilapia enteritis | |
| CN108785327A (en) | Improve composition, preparation method and the application of gastrointestinal health |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DD01 | Delivery of document by public notice |
Addressee: Zhang Tingli Document name: Notification of Passing Preliminary Examination of the Application for Invention |
|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110914 |