CN102143978B - 抗p2x7肽和表位 - Google Patents

抗p2x7肽和表位 Download PDF

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Publication number
CN102143978B
CN102143978B CN200980134521.3A CN200980134521A CN102143978B CN 102143978 B CN102143978 B CN 102143978B CN 200980134521 A CN200980134521 A CN 200980134521A CN 102143978 B CN102143978 B CN 102143978B
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China
Prior art keywords
antibody
receptor
antibodies
functional
receptors
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CN200980134521.3A
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English (en)
Chinese (zh)
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CN102143978A (zh
Inventor
J·A·巴登
A·基得利-拜尔德
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Biosceptre International Ltd
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Biosceptre International Ltd
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Priority claimed from AU2008903451A external-priority patent/AU2008903451A0/en
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Publication of CN102143978A publication Critical patent/CN102143978A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200980134521.3A 2008-07-04 2009-07-03 抗p2x7肽和表位 Active CN102143978B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2008903451A AU2008903451A0 (en) 2008-07-04 Composite peptide
AU2008903451 2008-07-04
PCT/AU2009/000869 WO2010000041A1 (en) 2008-07-04 2009-07-03 Anti- p2x7 peptides and epitopes

Publications (2)

Publication Number Publication Date
CN102143978A CN102143978A (zh) 2011-08-03
CN102143978B true CN102143978B (zh) 2015-02-18

Family

ID=41465424

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980134521.3A Active CN102143978B (zh) 2008-07-04 2009-07-03 抗p2x7肽和表位

Country Status (12)

Country Link
US (3) US8597643B2 (enExample)
EP (1) EP2318438B1 (enExample)
JP (2) JP5701752B2 (enExample)
KR (1) KR101701300B1 (enExample)
CN (1) CN102143978B (enExample)
AU (1) AU2009266430B2 (enExample)
BR (1) BRPI0915367B8 (enExample)
CA (1) CA2729868C (enExample)
ES (1) ES2610225T3 (enExample)
IL (2) IL210220A (enExample)
NZ (1) NZ590146A (enExample)
WO (1) WO2010000041A1 (enExample)

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DK1360203T3 (da) 2001-01-17 2009-04-20 Intreat Pty Ltd Antistoffer mod ikke-funktionel P2X7-receptordiagnose og behandling af cancerlidelser og andre tilstande
ATE542139T1 (de) 2007-09-14 2012-02-15 Biosceptre Int Ltd Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit
JP5670192B2 (ja) * 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規ｐ２ｘ７エピトープ
KR101701300B1 (ko) 2008-07-04 2017-02-01 바이오셉터 (어스트) 피티와이 엘티디 항­ｐ２ｘ７ 펩티드 및 에피토프
ES2904911T3 (es) 2009-08-20 2022-04-06 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
BR112012015561B1 (pt) 2009-12-24 2019-11-12 Biosceptre International Ltd anticorpos dirigidos contra receptores p2x7 oligoméricos não funcionais
CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
US9566318B2 (en) 2011-07-01 2017-02-14 Biosceptre (Aust) Pty Ltd Combination therapy
JP6790062B2 (ja) * 2015-04-02 2020-11-25 バイオセプター・（ユーケー）・リミテッド 疼痛治療
KR20180043841A (ko) * 2015-09-11 2018-04-30 카리나 바이오테크 피티와이 엘티디 키메라 항원 수용체 및 이의 용도
WO2018071959A1 (en) 2016-10-21 2018-04-26 Biosceptre (Uk) Limited Cytotoxic particles
BR112023020659A2 (pt) * 2021-04-08 2023-12-05 Biosceptre Aust Pty Ltd Métodos para controlar a atividade de célula imune
JP2025531021A (ja) * 2022-09-14 2025-09-19 バイオセプター （オースト） プロプライエタリー・リミテッド 免疫細胞を検出する方法
CN120187747A (zh) * 2022-09-14 2025-06-20 生物权威(澳大利亚)有限责任公司 工程化免疫细胞的富集
JP2025531030A (ja) * 2022-09-14 2025-09-19 バイオセプター （オースト） プロプライエタリー・リミテッド 免疫細胞のインビボ検出

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008043145A1 (en) * 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional p2x7 receptor

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EP0760850A1 (en) 1994-05-27 1997-03-12 Glaxo Group Limited P2x RECEPTORS (PURINOCEPTOR FAMILY)
EP0854923A2 (en) 1995-08-09 1998-07-29 Institut National De La Sante Et De La Recherche Medicale (Inserm) Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis
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EP1157038A4 (en) 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
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AU2002322192B2 (en) 2001-09-03 2008-05-01 Biosceptre International Limited Antibodies to non-functional P2X7receptor, diagnosis and treatment of cancers and other conditions
DK1473367T3 (da) 2003-04-17 2007-10-01 Affectis Pharmaceuticals Ag Midler og fremgangsmåder til diagnosticering og behandling af effektive lidelser
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ATE542139T1 (de) * 2007-09-14 2012-02-15 Biosceptre Int Ltd Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit
JP5670192B2 (ja) * 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規ｐ２ｘ７エピトープ
KR101701300B1 (ko) 2008-07-04 2017-02-01 바이오셉터 (어스트) 피티와이 엘티디 항­ｐ２ｘ７ 펩티드 및 에피토프
ES2904911T3 (es) * 2009-08-20 2022-04-06 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
BR112012015561B1 (pt) 2009-12-24 2019-11-12 Biosceptre International Ltd anticorpos dirigidos contra receptores p2x7 oligoméricos não funcionais
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CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
US9566318B2 (en) 2011-07-01 2017-02-14 Biosceptre (Aust) Pty Ltd Combination therapy

Patent Citations (1)

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Also Published As

Publication number Publication date
JP5701752B2 (ja) 2015-04-15
US20110110959A1 (en) 2011-05-12
US20160199442A1 (en) 2016-07-14
ES2610225T3 (es) 2017-04-26
BRPI0915367B1 (pt) 2020-10-13
BRPI0915367B8 (pt) 2021-05-25
US9328155B2 (en) 2016-05-03
BRPI0915367A2 (pt) 2015-11-03
KR101701300B1 (ko) 2017-02-01
IL210220A (en) 2016-04-21
IL232394A0 (en) 2014-06-30
IL232394A (en) 2016-04-21
US8597643B2 (en) 2013-12-03
CN102143978A (zh) 2011-08-03
NZ590146A (en) 2012-09-28
US20140135475A1 (en) 2014-05-15
EP2318438A4 (en) 2012-11-21
CA2729868A1 (en) 2010-01-07
EP2318438A1 (en) 2011-05-11
WO2010000041A1 (en) 2010-01-07
IL210220A0 (en) 2011-03-31
AU2009266430A8 (en) 2011-03-10
EP2318438B1 (en) 2016-11-02
AU2009266430B2 (en) 2014-08-14
JP2015038144A (ja) 2015-02-26
CA2729868C (en) 2018-07-10
US10238716B2 (en) 2019-03-26
JP2011526249A (ja) 2011-10-06
KR20110031222A (ko) 2011-03-24
AU2009266430A1 (en) 2010-01-07

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