JP5701752B2 - 抗ｐ２ｘ７ペプチドおよびエピトープ - Google Patents

抗ｐ２ｘ７ペプチドおよびエピトープ Download PDF

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Publication number
JP5701752B2
JP5701752B2 JP2011515029A JP2011515029A JP5701752B2 JP 5701752 B2 JP5701752 B2 JP 5701752B2 JP 2011515029 A JP2011515029 A JP 2011515029A JP 2011515029 A JP2011515029 A JP 2011515029A JP 5701752 B2 JP5701752 B2 JP 5701752B2
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Japan
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antibody
region
receptor
antibodies
functional
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Japanese (ja)
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JP2011526249A5 (enExample
JP2011526249A (ja
Inventor
ジュリアン・アレクサンダー・バーデン
アンガス・ギドリー−ベアード
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バイオセプター・インターナショナル・リミテッド
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Priority claimed from AU2008903451A external-priority patent/AU2008903451A0/en
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Publication of JP2011526249A publication Critical patent/JP2011526249A/ja
Publication of JP2011526249A5 publication Critical patent/JP2011526249A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2011515029A 2008-07-04 2009-07-03 抗ｐ２ｘ７ペプチドおよびエピトープ Active JP5701752B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2008903451 2008-07-04
AU2008903451A AU2008903451A0 (en) 2008-07-04 Composite peptide
PCT/AU2009/000869 WO2010000041A1 (en) 2008-07-04 2009-07-03 Anti- p2x7 peptides and epitopes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014222949A Division JP2015038144A (ja) 2008-07-04 2014-10-31 抗ｐ２ｘ７ペプチドおよびエピトープ

Publications (3)

Publication Number Publication Date
JP2011526249A JP2011526249A (ja) 2011-10-06
JP2011526249A5 JP2011526249A5 (enExample) 2013-10-24
JP5701752B2 true JP5701752B2 (ja) 2015-04-15

Family

ID=41465424

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011515029A Active JP5701752B2 (ja) 2008-07-04 2009-07-03 抗ｐ２ｘ７ペプチドおよびエピトープ
JP2014222949A Pending JP2015038144A (ja) 2008-07-04 2014-10-31 抗ｐ２ｘ７ペプチドおよびエピトープ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014222949A Pending JP2015038144A (ja) 2008-07-04 2014-10-31 抗ｐ２ｘ７ペプチドおよびエピトープ

Country Status (12)

Country Link
US (3) US8597643B2 (enExample)
EP (1) EP2318438B1 (enExample)
JP (2) JP5701752B2 (enExample)
KR (1) KR101701300B1 (enExample)
CN (1) CN102143978B (enExample)
AU (1) AU2009266430B2 (enExample)
BR (1) BRPI0915367B8 (enExample)
CA (1) CA2729868C (enExample)
ES (1) ES2610225T3 (enExample)
IL (2) IL210220A (enExample)
NZ (1) NZ590146A (enExample)
WO (1) WO2010000041A1 (enExample)

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* Cited by examiner, † Cited by third party
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CN101555283B (zh) 2001-01-17 2012-03-21 生物权威国际有限公司 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途
JP5670192B2 (ja) 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規ｐ２ｘ７エピトープ
WO2009033234A1 (en) 2007-09-14 2009-03-19 Biosceptre International Limited Purinergic (p2x) receptors in extra-cellular body fluid
AU2009266430B2 (en) 2008-07-04 2014-08-14 Biosceptre International Limited Anti- P2X7 peptides and epitopes
EP3395832B1 (en) 2009-08-20 2021-11-24 Biosceptre (Aust) Pty Ltd Anti p2x7 receptor antibodies and fragments thereof
EP2516470B1 (en) 2009-12-24 2018-02-07 Biosceptre (Aust) Pty Ltd Antibodies to non-functional oligomeric p2x7 receptors
WO2012031333A1 (en) 2010-09-10 2012-03-15 Biosceptre International Limited Companion animal treatments
WO2013003895A1 (en) * 2011-07-01 2013-01-10 Biosceptre International Limited Combination therapy
CN107614528A (zh) * 2015-04-02 2018-01-19 生物权威（英国）有限公司 疼痛治疗
US12121539B2 (en) 2015-09-11 2024-10-22 Biosceptre (Aust) Pty Ltd Chimeric antigen receptors and uses thereof
CN109862883A (zh) 2016-10-21 2019-06-07 生物权威（英国）有限公司 细胞毒性颗粒
AU2019275479B2 (en) 2018-05-21 2022-12-08 Biosceptre (Aust) Pty Ltd Chimeric antigen receptors with modified linker domains and uses thereof
BR112023020659A2 (pt) * 2021-04-08 2023-12-05 Biosceptre Aust Pty Ltd Métodos para controlar a atividade de célula imune
CN120187461A (zh) * 2022-09-14 2025-06-20 生物权威(澳大利亚)有限责任公司 免疫细胞的体内检测
JP2025531675A (ja) * 2022-09-14 2025-09-25 バイオセプター （オースト） プロプライエタリー・リミテッド 操作された免疫細胞の富化
US20260085104A1 (en) * 2022-09-14 2026-03-26 Biosceptre (Aust) Pty Ltd Methods of detecting immune cells

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EP0760850A1 (en) 1994-05-27 1997-03-12 Glaxo Group Limited P2x RECEPTORS (PURINOCEPTOR FAMILY)
US5981218A (en) 1995-08-09 1999-11-09 Bristol-Myers Squibb Company Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides
JP2001521372A (ja) 1996-04-30 2001-11-06 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ヒトＰ２ｘ４レセプタースプライス−変異体
US6303338B1 (en) * 1996-08-16 2001-10-16 Human Genome Sciences, Inc. Pancreas-derived plasminogen activator inhibitor
US6306393B1 (en) * 1997-03-24 2001-10-23 Immunomedics, Inc. Immunotherapy of B-cell malignancies using anti-CD22 antibodies
JP3885177B2 (ja) 1997-03-26 2007-02-21 大塚製薬株式会社 ヒト遺伝子
US6133434A (en) * 1997-04-28 2000-10-17 Glaxo Group Limited Purinergic receptor
DE69941187D1 (de) * 1998-06-01 2009-09-10 Agensys Inc Serpentintransmembranantigene exprimiert in menschlichem krebs und deren verwendungen
DE19829473C2 (de) * 1998-07-01 2000-08-10 Magnus Von Knebel Doeberitz Ch Verfahren zur frühen Diagnose von Carcinomen
EP1157038A4 (en) 1999-02-26 2005-01-19 Smithkline Beecham Corp CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17)
AUPP991199A0 (en) 1999-04-21 1999-05-13 University Of Sydney, The Methods for diagnosing pre-cancerous and cancerous conditions
WO2001030964A2 (en) 1999-10-22 2001-05-03 Lifespan Biosciences, Inc. Anti-cancer nucleic acid and protein targets
AU2001274902A1 (en) * 2000-12-06 2002-06-18 Linex Technologies, Inc. Efficient sharing of capacity by remote stations using circuit switching and packet switching
AUPR201500A0 (en) * 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
WO2003020762A1 (en) * 2001-09-03 2003-03-13 Intreat Pty Limited Antibodies to non-functional p2x7receptor, diagnosis and treatment of cancers and other conditions
CN101555283B (zh) * 2001-01-17 2012-03-21 生物权威国际有限公司 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途
PL1469072T3 (pl) 2003-04-17 2008-03-31 Affectis Pharmaceuticals Ag Środki i sposoby diagnozowania i leczenia chorób afektywnych
US20090215727A1 (en) * 2005-05-05 2009-08-27 Medicure International Inc. Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphate and vitamin b6 related compounds
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WO2008043145A1 (en) * 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional p2x7 receptor
US20100036101A1 (en) * 2006-10-10 2010-02-11 Angus Gidley-Baird Antibodies against non functional p2x7 receptor
JP5670192B2 (ja) 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規ｐ２ｘ７エピトープ
WO2009033234A1 (en) 2007-09-14 2009-03-19 Biosceptre International Limited Purinergic (p2x) receptors in extra-cellular body fluid
AU2009266430B2 (en) 2008-07-04 2014-08-14 Biosceptre International Limited Anti- P2X7 peptides and epitopes
EP3395832B1 (en) * 2009-08-20 2021-11-24 Biosceptre (Aust) Pty Ltd Anti p2x7 receptor antibodies and fragments thereof
EP2516470B1 (en) 2009-12-24 2018-02-07 Biosceptre (Aust) Pty Ltd Antibodies to non-functional oligomeric p2x7 receptors
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WO2013003895A1 (en) 2011-07-01 2013-01-10 Biosceptre International Limited Combination therapy

Also Published As

Publication number Publication date
US8597643B2 (en) 2013-12-03
KR20110031222A (ko) 2011-03-24
KR101701300B1 (ko) 2017-02-01
IL210220A (en) 2016-04-21
JP2015038144A (ja) 2015-02-26
CA2729868C (en) 2018-07-10
CN102143978A (zh) 2011-08-03
US20110110959A1 (en) 2011-05-12
NZ590146A (en) 2012-09-28
BRPI0915367B8 (pt) 2021-05-25
WO2010000041A1 (en) 2010-01-07
CN102143978B (zh) 2015-02-18
EP2318438A1 (en) 2011-05-11
AU2009266430A8 (en) 2011-03-10
BRPI0915367A2 (pt) 2015-11-03
US20140135475A1 (en) 2014-05-15
US9328155B2 (en) 2016-05-03
CA2729868A1 (en) 2010-01-07
IL232394A0 (en) 2014-06-30
IL232394A (en) 2016-04-21
US20160199442A1 (en) 2016-07-14
US10238716B2 (en) 2019-03-26
BRPI0915367B1 (pt) 2020-10-13
IL210220A0 (en) 2011-03-31
ES2610225T3 (es) 2017-04-26
EP2318438B1 (en) 2016-11-02
JP2011526249A (ja) 2011-10-06
EP2318438A4 (en) 2012-11-21
AU2009266430B2 (en) 2014-08-14
AU2009266430A1 (en) 2010-01-07

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