CN102138991B - Pharmaceutical composition for treating oral cancer and skin cancer - Google Patents

Pharmaceutical composition for treating oral cancer and skin cancer Download PDF

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CN102138991B
CN102138991B CN2011100882817A CN201110088281A CN102138991B CN 102138991 B CN102138991 B CN 102138991B CN 2011100882817 A CN2011100882817 A CN 2011100882817A CN 201110088281 A CN201110088281 A CN 201110088281A CN 102138991 B CN102138991 B CN 102138991B
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herba
radix
pharmaceutical composition
semen
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CN102138991A (en
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王兴礼
李运箱
王修强
王建广
赵伟
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Rudong County Chahe Sewage Treatment Co Ltd
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Abstract

The invention discloses a pharmaceutical composition for treating oral cancer and skin cancer, comprising the following active components in parts by weight: 180-220 parts of semen momordicae (fried), 45-55 parts of barbat skullcap, 45-55 parts of Chinese lobelia, 90-110 parts of rhubarb, 45-55 parts of oldenlandia diffusa, 90-110 parts of radix euphorbiae lantu, 18-22 parts of notoginseng, 27-33 parts of spina gleditsiae, 90-110 parts of nux vomica (fried), 45-55 parts of wild ginger, 45-55 parts of wistaria, 45-55 parts of myrrh, 90-110 parts of rhus chinensis mill, 45-55 parts of dried alum, 18-22 parts of sal ammoniac, 27-33 parts of dragon bone (calcined) 18-22 parts of gecko, 8-12 parts of black-tail snake, 27-33 parts of centipede, 18-22 parts of mother of pearl and 18-22 parts of paludine. Compared with the prior art, the pharmaceutical composition for treating oral cancer and skin cancer has the advantages of quick effect taking speed, high efficiency, high cure rate, no side effect and low treatment cost.

Description

A kind of pharmaceutical composition for the treatment of oral cancer, skin carcinoma
Technical field
The present invention relates to the medical medicine technical field, particularly relate to a kind of pharmaceutical composition that is used for the treatment of cancer.
Background technology
At present, the medicine for the treatment of oral cavity, skin cancer is many, hemoporphyrin, XIAOAIPING PIAN, cinobufacin sheet etc.Conventional method mainly contains operation and cuts off technology and radio-frequency ablation technique.The treatment time of these medicines and method is long, and cure rate is low, and therapeutic effect is poor, and economic cost is high, brings great spirit and financial burden to the patient.
Summary of the invention
The objective of the invention is to overcome the problem that existing treatment technology and medicine exist, provide a kind of treat oral cavity, skin cancer rapidly and efficiently, cure rate is high, have no side effect, pharmaceutical composition that treatment cost is low.
The object of the present invention is achieved like this: a kind of pharmaceutical composition for the treatment of oral cancer, skin carcinoma, active component by following weight portion forms: Semen Momordicae (stir-fry) 180-220 part, Herba Scutellariae Barbatae 45-55 part, Herba Lobeliae Chinensis 45-55 part, Radix Et Rhizoma Rhei 90-110 part, Herba Hedyotidis Diffusae 45-55 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 90-110 part, Radix Notoginseng 18-22 part, Spina Gleditsiae 27-33 part; Semen Strychni (stir-fry) 90-110 part, Herba Asari 45-55 part, Caulis wisteriae sinensis 45-55 part, Myrrha 45-55 part, Galla Chinensis 90-110 part; Dried Alumen 45-55 part, Sal Ammoniacus 18-22 part, Os Draconis (forging) 27-33 part; Gekko Swinhonis (referring to Gekko Swinhonis) 18-22 part, Zaocys 8-12 part, Scolopendra 27-33 part, Concha Margaritifera 18-22 part, Cipangopaludina chinensis 18-22 part.
In a preferred embodiment, the pharmaceutical composition for the treatment of oral cancer of the present invention, skin carcinoma, active component by following weight portion forms: 200 parts of Semen Momordicaes (stir-fry), 50 parts of Herba Scutellariae Barbataes, 50 parts of Herba Lobeliae Chinensis, 100 parts of Radix Et Rhizoma Rhei, 50 parts of Herba Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychni (stir-fry), 50 parts of Herba Asaris, 50 parts, Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of Galla Chinensiss; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis (forging); 20 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
In another preferred embodiment, the pharmaceutical composition for the treatment of oral cancer of the present invention, skin carcinoma, active component by following weight portion forms: 180 parts of Semen Momordicaes (stir-fry), 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Herba Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychni (stir-fry), 45 parts of Herba Asaris, 45 parts, Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of Galla Chinensiss; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
In another preferred embodiment, the pharmaceutical composition for the treatment of oral cancer of the present invention, skin carcinoma, it is characterized in that: the active component by following weight portion forms: 220 parts of Semen Momordicaes (stir-fry), 54 parts of Herba Scutellariae Barbataes, 55 parts of Herba Lobeliae Chinensis, 110 parts of Radix Et Rhizoma Rhei, 54 parts of Herba Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 22 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 110 parts of Semen Strychni (stir-fry), 55 parts of Herba Asaris, 55 parts, Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of Galla Chinensiss; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis (forging); 22 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
The pharmaceutical composition of above-mentioned arbitrary described treatment oral cancer, skin carcinoma, it is injection, unguentum or powder.
The preparation method that above-mentioned each Chinese medicinal components is prepared into compound preparation of the present invention is:
Take the above-mentioned Chinese medicine crude drug of recipe quantity; first Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, Galla Chinensis; after adding 3 times of water gagings; boiled with vigorous fire, then burnt 3 hours with slow fire, add Myrrha after truce; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis (referring to Gekko Swinhonis), Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate approximately 15%) to pulverize, and adds appropriate excipient, such as cane sugar powder, makes 40 order dissolved granulies and packing.Every bag 10g, taking after mixing it with water with the 150ml boiled water gets final product.
Usage and dosage: each serving 1 bag, take every day 2 times.
The present invention has advantages of following beneficial effect and significant progressive: rapidly and efficiently, cure rate is high, have no side effect, treatment cost is low.
The specific embodiment
Be below specific embodiments of the invention, technical scheme of the present invention is done further the description, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.
The preparation of the pharmaceutical composition of embodiment 1 treatment oral cancer, skin carcinoma
Crude drug prescription: 190 parts of Semen Momordicaes (stir-fry), 48 parts of Herba Scutellariae Barbataes, 46 parts of Herba Lobeliae Chinensis, 98 parts of Radix Et Rhizoma Rhei, 50 parts of Herba Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychni (stir-fry), 50 parts of Herba Asaris, 50 parts, Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of Galla Chinensiss; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis (forging); 20 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes recipe quantity; first Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, Galla Chinensis; after adding 3 times of water gagings; boiled with vigorous fire, then burnt 3 hours with slow fire, add Myrrha after truce; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis (referring to Gekko Swinhonis), Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate approximately 15%) to pulverize, and adds appropriate cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
The preparation of the pharmaceutical composition of embodiment 2 treatment oral cancer, skin carcinoma
Crude drug prescription: 180 parts of Semen Momordicaes (stir-fry), 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Herba Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychni (stir-fry), 45 parts of Herba Asaris, 45 parts, Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of Galla Chinensiss; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes recipe quantity; first Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, Galla Chinensis; after adding 3 times of water gagings; boiled with vigorous fire, then burnt 3 hours with slow fire, add Myrrha after truce; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis (referring to Gekko Swinhonis), Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate approximately 15%) to pulverize, and adds appropriate cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
The preparation of the pharmaceutical composition of embodiment 3 treatment oral cancer, skin carcinoma
Crude drug prescription: 210 parts of Semen Momordicaes (stir-fry), 54 parts of Herba Scutellariae Barbataes, 53 parts of Herba Lobeliae Chinensis, 108 parts of Radix Et Rhizoma Rhei, 54 parts of Herba Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 21 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 107 parts of Semen Strychni (stir-fry), 55 parts of Herba Asaris, 55 parts, Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of Galla Chinensiss; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis (forging); 22 parts of Gekko Swinhoniss (referring to Gekko Swinhonis), 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes recipe quantity; first Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Herba Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, Galla Chinensis; after adding 3 times of water gagings; boiled with vigorous fire, then burnt 3 hours with slow fire, add Myrrha after truce; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis (referring to Gekko Swinhonis), Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate approximately 15%) to pulverize, and adds appropriate cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
Medicine of the present invention is pure Chinese medicine, and formula meets theory of Chinese medical science, through for many years facts have proved its have heat-clearing and toxic substances removing, strengthening the body resistance, assault fortified position except tumor, drag inner pus, hemostasis and pain-relieving, antiinflammatory dampness, except necrotic tissue and promoting muscle growing, kill eight large functions of cancerous cell.
For showing that medicine of the present invention is to the therapeutic effect of oral cavity cancer, skin cancer, the present invention is through the clinical observation of 1000 routine oral cavity cancer patients and 1000 routine skin cancer systems, observation period is 90 days, the recovery from illness tumor disappears and is produce effects, the tumor growth of not fully recovering is obstructed as effectively, and tumor growth is normally invalid.
Using method: each serving 1 bag, every bag 10g, taking after mixing it with water with the 150ml boiled water gets final product, and takes every day 2 times.Clinical test results sees Table one.
Table one: use medicine of the present invention to oral cavity cancer, skin cancer patient's observation of curative effect.
Group Case load Produce effects (number of cases) Effectively (number of cases) Invalid (number of cases) Total effective rate (%)
The oral cancer group 1000 921 79 0 100
The skin carcinoma group 1000 918 82 0 100
As can be seen from Table I, medicine of the present invention is to 1000 routine oral cavity cancer patients, and obtaining significant curative effect has 921 examples, accounts for 92.1%; That takes a turn for the better has 79 examples, accounts for 7.9%; Total effective rate 100%.Medicine of the present invention is to 1000 routine skin cancer patients, and obtaining significant curative effect has 918 examples, accounts for 91.8%; That takes a turn for the better has 82 examples, accounts for 8.2%; Total effective rate 100%.

Claims (4)

1. pharmaceutical composition for the treatment of oral cancer, skin carcinoma, it is characterized in that: the active component by following weight portion forms: Semen Momordicae 180-220 part, Herba Scutellariae Barbatae 45-55 part, Herba Lobeliae Chinensis 45-55 part, Radix Et Rhizoma Rhei 90-110 part, Herba Hedyotidis Diffusae 45-55 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 90-110 part, Radix Notoginseng 18-22 part, Spina Gleditsiae 27-33 part; Semen Strychni 90-110 part, Herba Asari 45-55 part, Caulis wisteriae sinensis 45-55 part, Myrrha 45-55 part, Galla Chinensis 90-110 part; Dried Alumen 45-55 part, Sal Ammoniacus 18-22 part, Os Draconis 27-33 part; Gekko Swinhonis 18-22 part, Zaocys 8-12 part, Scolopendra 27-33 part, Concha Margaritifera 18-22 part, Cipangopaludina chinensis 18-22 part.
2. the pharmaceutical composition for the treatment of oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion forms: 200 parts of Semen Momordicaes, 50 parts of Herba Scutellariae Barbataes, 50 parts of Herba Lobeliae Chinensis, 100 parts of Radix Et Rhizoma Rhei, 50 parts of Herba Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychni, 50 parts of Herba Asaris, 50 parts, Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of Galla Chinensiss; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis; 20 parts of Gekko Swinhoniss, 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
3. the pharmaceutical composition for the treatment of oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion forms: 180 parts of Semen Momordicaes, 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Herba Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychni, 45 parts of Herba Asaris, 45 parts, Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of Galla Chinensiss; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss, 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
4. the pharmaceutical composition for the treatment of oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion forms: 220 parts of Semen Momordicaes, 54 parts of Herba Scutellariae Barbataes, 55 parts of Herba Lobeliae Chinensis, 110 parts of Radix Et Rhizoma Rhei, 54 parts of Herba Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 22 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 110 parts of Semen Strychni, 55 parts of Herba Asaris, 55 parts, Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of Galla Chinensiss; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis; 22 parts of Gekko Swinhoniss, 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
CN2011100882817A 2011-04-10 2011-04-10 Pharmaceutical composition for treating oral cancer and skin cancer Active CN102138991B (en)

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CN104208525A (en) * 2013-05-31 2014-12-17 吴本汉 Traditional Chinese medicine composition for treating skin cancer

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1539455A (en) * 2003-10-27 2004-10-27 李林龙 Medical combination possessing effect for turning cancer off and rejuvenation
CN1265901C (en) * 2001-04-25 2006-07-26 Sms德马格股份公司 Rolling mill base for rail like rolling material
CN101049484A (en) * 2007-05-14 2007-10-10 郝来勤 Strong effective Chinese traditional medicine for treating lung cancer and other various cancers

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Publication number Priority date Publication date Assignee Title
CN1265901A (en) * 2000-01-26 2000-09-13 徐忠廷 Traditional Chinese medicinal pill for anti-cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1265901C (en) * 2001-04-25 2006-07-26 Sms德马格股份公司 Rolling mill base for rail like rolling material
CN1539455A (en) * 2003-10-27 2004-10-27 李林龙 Medical combination possessing effect for turning cancer off and rejuvenation
CN101049484A (en) * 2007-05-14 2007-10-10 郝来勤 Strong effective Chinese traditional medicine for treating lung cancer and other various cancers

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