CN102138991A - Pharmaceutical composition for treating oral cancer and skin cancer - Google Patents

Pharmaceutical composition for treating oral cancer and skin cancer Download PDF

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Publication number
CN102138991A
CN102138991A CN2011100882817A CN201110088281A CN102138991A CN 102138991 A CN102138991 A CN 102138991A CN 2011100882817 A CN2011100882817 A CN 2011100882817A CN 201110088281 A CN201110088281 A CN 201110088281A CN 102138991 A CN102138991 A CN 102138991A
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parts
radix
herba
fry
stir
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CN102138991B (en
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王兴礼
李运箱
王修强
王建广
赵伟
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Rudong County Chahe Sewage Treatment Co Ltd
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Abstract

The invention discloses a pharmaceutical composition for treating oral cancer and skin cancer, comprising the following active components in parts by weight: 180-220 parts of semen momordicae (fried), 45-55 parts of barbat skullcap, 45-55 parts of Chinese lobelia, 90-110 parts of rhubarb, 45-55 parts of oldenlandia diffusa, 90-110 parts of radix euphorbiae lantu, 18-22 parts of notoginseng, 27-33 parts of spina gleditsiae, 90-110 parts of nux vomica (fried), 45-55 parts of wild ginger, 45-55 parts of wistaria, 45-55 parts of myrrh, 90-110 parts of rhus chinensis mill, 45-55 parts of dried alum, 18-22 parts of sal ammoniac, 27-33 parts of dragon bone (calcined) 18-22 parts of gecko, 8-12 parts of black-tail snake, 27-33 parts of centipede, 18-22 parts of mother of pearl and 18-22 parts of paludine. Compared with the prior art, the pharmaceutical composition for treating oral cancer and skin cancer has the advantages of quick effect taking speed, high efficiency, high cure rate, no side effect and low treatment cost.

Description

A kind of pharmaceutical composition for the treatment of oral cancer, skin carcinoma
Technical field
The present invention relates to the medical medicine technical field, particularly relate to a kind of pharmaceutical composition that is used for the treatment of cancer.
Background technology
At present, the medicine of treatment oral cavity, skin cancer is many, hemoporphyrin, XIAOAIPING PIAN, cinobufacin sheet etc.Conventional method mainly contains operation and cuts off technology and radio-frequency ablation technique.The treatment time of these medicines and method is long, and cure rate is low, and therapeutic effect is poor, and the economic cost height brings great spirit and financial burden to the patient.
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Summary of the invention
The objective of the invention is to overcome the problem that existing treatment technology and medicine exist, provide a kind of treat oral cavity, skin cancer rapidly and efficiently, the cure rate height, have no side effect, treat the low pharmaceutical composition of cost.
The object of the present invention is achieved like this: a kind of pharmaceutical composition for the treatment of oral cancer, skin carcinoma, active component by following weight portion is formed: Semen Momordicae (stir-fry) 180-220 part, Herba Scutellariae Barbatae 45-55 part, Herba Lobeliae Chinensis 45-55 part, Radix Et Rhizoma Rhei 90-110 part, Hedyotidis Diffusae 45-55 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 90-110 part, Radix Notoginseng 18-22 part, Spina Gleditsiae 27-33 part; Semen Strychni (stir-fry) 90-110 part, Herba Asari 45-55 part, Caulis wisteriae sinensis 45-55 part, Myrrha 45-55 part, WUXINZI 90-110 part; Dried Alumen 45-55 part, Sal Ammoniacus 18-22 part, Os Draconis (forging) 27-33 part; Gekko Swinhonis 18-22 part, Zaocys 8-12 part, Scolopendra 27-33 part, Concha Margaritifera 18-22 part, Cipangopaludina chinensis 18-22 part.
In a preferred embodiment, the pharmaceutical composition of treatment oral cancer of the present invention, skin carcinoma, active component by following weight portion is formed: 200 parts of Semen Momordicaes (stir-fry), 50 parts of Herba Scutellariae Barbataes, 50 parts of Herba Lobeliae Chinensis, 100 parts of Radix Et Rhizoma Rhei, 50 parts of Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychnis (stir-fry), 50 parts of Herba Asaris, 50 parts in Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of WUXINZI; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis (forging); 20 parts of Gekko Swinhoniss, 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
In another preferred embodiment, the pharmaceutical composition of treatment oral cancer of the present invention, skin carcinoma, active component by following weight portion is formed: 180 parts of Semen Momordicaes (stir-fry), 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychnis (stir-fry), 45 parts of Herba Asaris, 45 parts in Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of WUXINZI; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss, 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
In another preferred embodiment, the pharmaceutical composition of treatment oral cancer of the present invention, skin carcinoma, it is characterized in that: the active component by following weight portion is formed: 220 parts of Semen Momordicaes (stir-fry), 54 parts of Herba Scutellariae Barbataes, 55 parts of Herba Lobeliae Chinensis, 110 parts of Radix Et Rhizoma Rhei, 54 parts of Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 22 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 110 parts of Semen Strychnis (stir-fry), 55 parts of Herba Asaris, 55 parts in Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of WUXINZI; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis (forging); 22 parts of Gekko Swinhoniss, 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
The pharmaceutical composition of above-mentioned arbitrary described treatment oral cancer, skin carcinoma, it is injection, unguentum or powder.
The preparation method that above-mentioned each Chinese medicinal components is prepared into compound preparation of the present invention is:
Take by weighing the above-mentioned Chinese medicine crude drug of recipe quantity; earlier Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, WUXINZI; after adding 3 times of water gagings; boiled with vigorous fire, to burn 3 hours with slow fire then, the back of ceasing fire adds Myrrha; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis, Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in the stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate about 15%) to pulverize, and adds an amount of excipient, such as cane sugar powder, makes 40 order dissolved granulies and packing.Every bag 10g, taking after mixing it with water with the 150ml boiled water gets final product.
Usage and dosage: obey 1 bag at every turn, obey every day 2 times.
The present invention has following beneficial effect and obvious improvement: rapidly and efficiently, the cure rate height, have no side effect, treat the low advantage of cost.
The specific embodiment
Below be specific embodiments of the invention, technical scheme of the present invention is done further the description, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.
The preparation of drug combination of embodiment 1 treatment oral cancer, skin carcinoma
Crude drug prescription: 190 parts of Semen Momordicaes (stir-fry), 48 parts of Herba Scutellariae Barbataes, 46 parts of Herba Lobeliae Chinensis, 98 parts of Radix Et Rhizoma Rhei, 50 parts of Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychnis (stir-fry), 50 parts of Herba Asaris, 50 parts in Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of WUXINZI; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis (forging); 20 parts of Gekko Swinhoniss, 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes by weighing recipe quantity; earlier Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, WUXINZI; after adding 3 times of water gagings; boiled with vigorous fire, to burn 3 hours with slow fire then, the back of ceasing fire adds Myrrha; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis, Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in the stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate about 15%) to pulverize, and adds an amount of cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
The preparation of drug combination of embodiment 2 treatment oral cancer, skin carcinoma
Crude drug prescription: 180 parts of Semen Momordicaes (stir-fry), 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychnis (stir-fry), 45 parts of Herba Asaris, 45 parts in Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of WUXINZI; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss, 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes by weighing recipe quantity; earlier Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, WUXINZI; after adding 3 times of water gagings; boiled with vigorous fire, to burn 3 hours with slow fire then, the back of ceasing fire adds Myrrha; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis, Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in the stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate about 15%) to pulverize, and adds an amount of cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
The preparation of drug combination of embodiment 3 treatment oral cancer, skin carcinoma
Crude drug prescription: 210 parts of Semen Momordicaes (stir-fry), 54 parts of Herba Scutellariae Barbataes, 53 parts of Herba Lobeliae Chinensis, 108 parts of Radix Et Rhizoma Rhei, 54 parts of Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 21 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 107 parts of Semen Strychnis (stir-fry), 55 parts of Herba Asaris, 55 parts in Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of WUXINZI; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis (forging); 22 parts of Gekko Swinhoniss, 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
Preparation method: the above-mentioned Chinese medicine crude drug that takes by weighing recipe quantity; earlier Semen Momordicae, Semen Strychni are fried to yellowish-brown with pot; mix with Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Radix Et Rhizoma Rhei, Hedyotidis Diffusae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Radix Notoginseng, Spina Gleditsiae, Semen Strychni, Herba Asari, Caulis wisteriae sinensis, WUXINZI; after adding 3 times of water gagings; boiled with vigorous fire, to burn 3 hours with slow fire then, the back of ceasing fire adds Myrrha; be cooled to 40 degree, filter.Dried Alumen, Sal Ammoniacus, Os Draconis (forging), Gekko Swinhonis, Zaocys, Scolopendra, Concha Margaritifera, Cipangopaludina chinensis are mixed with above-mentioned gained medicinal liquid, add 2 times of water gagings and fried in shallow oil 3 hours, filter.Filtering residue adds 4 times of water gagings to be fried in shallow oil 2 hours, filtered.Twice filtrate merges, and places sedimentation more than 12 hours, gets supernatant and is evaporated to extractum below 60 ℃ and contains crude drug 2g/ml.Extractum is put in the stainless steel disc, and vacuum drying (below 60 ℃) claims dried cream (extractum rate about 15%) to pulverize, and adds an amount of cane sugar powder, makes 40 order dissolved granulies and packing, every bag 10g.
Medicine of the present invention is pure Chinese medicine, and prescription meets theory of Chinese medical science, through for many years facts have proved its have heat-clearing and toxic substances removing, strengthening the body resistance, assault fortified position except that tumor, drag in saturating pus, hemostasis and pain-relieving, antiinflammatory dampness, remove necrotic tissue and promoting muscle growing, kill eight big functions of cancerous cell.
For showing the therapeutic effect of medicine of the present invention to oral cavity cancer, skin cancer, the present invention is through the clinical observation of 1000 routine oral cavity cancer patients and 1000 routine skin cancer systems, observation period is 90 days, the recovery from illness tumor disappears and is produce effects, the tumor growth of not fully recovering is obstructed to effectively, and tumor growth normally is invalid.
Using method: obey 1 bag at every turn, every bag 10g, taking after mixing it with water with the 150ml boiled water gets final product, and obeys every day 2 times.Clinical test results sees Table one.
Table one: use the observation of curative effect of medicine of the present invention to oral cavity cancer, skin cancer patient.
Group Case load Produce effects (routine number) Effectively (routine number) Invalid (routine number) Total effective rate (%)
The oral cancer group 1000 921 79 0 100
The skin carcinoma group 1000 918 82 0 100
As can be seen from Table I, medicine of the present invention is to 1000 routine oral cavity cancer patients, and obtaining significant curative effect has 921 examples, accounts for 92.1%; That takes a turn for the better has 79 examples, accounts for 7.9%; Total effective rate 100%.Medicine of the present invention is to 1000 routine skin cancer patients, and obtaining significant curative effect has 918 examples, accounts for 91.8%; That takes a turn for the better has 82 examples, accounts for 8.2%; Total effective rate 100%.

Claims (5)

1. pharmaceutical composition for the treatment of oral cancer, skin carcinoma, it is characterized in that: the active component by following weight portion is formed: Semen Momordicae (stir-fry) 180-220 part, Herba Scutellariae Barbatae 45-55 part, Herba Lobeliae Chinensis 45-55 part, Radix Et Rhizoma Rhei 90-110 part, Hedyotidis Diffusae 45-55 part, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 90-110 part, Radix Notoginseng 18-22 part, Spina Gleditsiae 27-33 part; Semen Strychni (stir-fry) 90-110 part, Herba Asari 45-55 part, Caulis wisteriae sinensis 45-55 part, Myrrha 45-55 part, WUXINZI 90-110 part; Dried Alumen 45-55 part, Sal Ammoniacus 18-22 part, Os Draconis (forging) 27-33 part; Gekko Swinhonis 18-22 part, Zaocys 8-12 part, Scolopendra 27-33 part, Concha Margaritifera 18-22 part, Cipangopaludina chinensis 18-22 part.
2. the pharmaceutical composition of treatment oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion is formed: 200 parts of Semen Momordicaes (stir-fry), 50 parts of Herba Scutellariae Barbataes, 50 parts of Herba Lobeliae Chinensis, 100 parts of Radix Et Rhizoma Rhei, 50 parts of Hedyotidis Diffusaes, 100 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 20 parts of Radix Notoginseng, 30 parts of Spina Gleditsiaes; 100 parts of Semen Strychnis (stir-fry), 50 parts of Herba Asaris, 50 parts in Caulis wisteriae sinensis, 50 parts of Myrrhas, 100 parts of WUXINZI; 50 parts of dried Alumens, 20 parts of Sal Ammoniacuss, 30 parts of Os Draconis (forging); 20 parts of Gekko Swinhoniss, 10 parts of Zaocyss, 30 parts of Scolopendras, 20 parts of Concha Margaritiferas, 20 parts of Cipangopaludina chinensiss.
3. the pharmaceutical composition of treatment oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion is formed: 180 parts of Semen Momordicaes (stir-fry), 46 parts of Herba Scutellariae Barbataes, 45 parts of Herba Lobeliae Chinensis, 90 parts of Radix Et Rhizoma Rhei, 45 parts of Hedyotidis Diffusaes, 91 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 18 parts of Radix Notoginseng, 27 parts of Spina Gleditsiaes; 90 parts of Semen Strychnis (stir-fry), 45 parts of Herba Asaris, 45 parts in Caulis wisteriae sinensis, 45 parts of Myrrhas, 90 parts of WUXINZI; 45 parts of dried Alumens, 18 parts of Sal Ammoniacuss, 27 parts of Os Draconis; 18 parts of Gekko Swinhoniss, 8 parts of Zaocyss, 27 parts of Scolopendras, 18 parts of Concha Margaritiferas, 18 parts of Cipangopaludina chinensiss.
4. the pharmaceutical composition of treatment oral cancer as claimed in claim 1, skin carcinoma, it is characterized in that: the active component by following weight portion is formed: 220 parts of Semen Momordicaes (stir-fry), 54 parts of Herba Scutellariae Barbataes, 55 parts of Herba Lobeliae Chinensis, 110 parts of Radix Et Rhizoma Rhei, 54 parts of Hedyotidis Diffusaes, 110 parts of the Radixs Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), 22 parts of Radix Notoginseng, 33 parts of Spina Gleditsiaes; 110 parts of Semen Strychnis (stir-fry), 55 parts of Herba Asaris, 55 parts in Caulis wisteriae sinensis, 55 parts of Myrrhas, 110 parts of WUXINZI; 55 parts of dried Alumens, 22 parts of Sal Ammoniacuss, 33 parts of Os Draconis (forging); 22 parts of Gekko Swinhoniss, 12 parts of Zaocyss, 33 parts of Scolopendras, 22 parts of Concha Margaritiferas, 22 parts of Cipangopaludina chinensiss.
5. as the pharmaceutical composition of the arbitrary described treatment oral cancer of claim 1-4, skin carcinoma, it is characterized in that: it is injection, unguentum or powder.
CN2011100882817A 2011-04-10 2011-04-10 Pharmaceutical composition for treating oral cancer and skin cancer Active CN102138991B (en)

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CN104208525A (en) * 2013-05-31 2014-12-17 吴本汉 Traditional Chinese medicine composition for treating skin cancer

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CN101049484A (en) * 2007-05-14 2007-10-10 郝来勤 Strong effective Chinese traditional medicine for treating lung cancer and other various cancers

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CN1539455A (en) * 2003-10-27 2004-10-27 李林龙 Medical combination possessing effect for turning cancer off and rejuvenation
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208525A (en) * 2013-05-31 2014-12-17 吴本汉 Traditional Chinese medicine composition for treating skin cancer

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Patentee after: Rudong County Chahe sewage treatment Co. Ltd.

Address before: 266200 Jimo, Shandong, the Yellow River Road No. two, No. 182, No.

Patentee before: Cui Hefang