CN102908423B - Traditional Chinese medicine composition for treating stones - Google Patents
Traditional Chinese medicine composition for treating stones Download PDFInfo
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- CN102908423B CN102908423B CN201210458410.1A CN201210458410A CN102908423B CN 102908423 B CN102908423 B CN 102908423B CN 201210458410 A CN201210458410 A CN 201210458410A CN 102908423 B CN102908423 B CN 102908423B
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Abstract
The invention discloses a Chinese medicinal composition for treating stones. The composition comprises the following raw material drugs in parts by weight: 1 to 20 parts of giant knot weed, 3 to 18 parts of lysimachia nummularia aurea, 5 to 20 parts of centella, and 1 to 15 parts of Japanese raspberry root. The Chinese medicinal composition is simple in prescription, has low price and easily available raw material drugs and low treatment cost, can be taken as long as the composition is decocted or immersed with boiled water, and is convenient in using. The composition plays roles in clearing heat and promoting diuresis, removing stasis, and removing and dissolving stones, and is excellent in curative effect to stones in liver, gallbladder, kidney and urinary tract.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition that is used for the treatment of calculus, belong to the field of Chinese medicines.
Background technology
Calculus, refers to that some position forms and stagnates as sick sandstone sample pathological product or caking in vivo.Calculus the greater is difficult to discharge, therefore be detained, causes a disease more, and prevalence approximately 15%, and on the rise year by year.Common are cholelithiasis, hepatolithiasis, renal calculus, lithangiuria etc.The origin cause of formation of calculus is comparatively complicated, common because have improper diet, feelings will internal injury, take medicine improper and body constitution difference etc.
At present, the method for the treatment of calculus has western medicine therapy and tcm therapy.The former mainly take excision stone location as main, but that operation meeting brings to patient is many unfavorable and painful, and the postoperative possibility that still has again calculus, so Most patients is all reluctant to select operative therapy; The conservative treatment of other doctors trained in Western medicine mainly adopts the method for antiinflammatory, pain relieving, function of gallbladder promoting, diuresis, but these class methods can not be effected a radical cure calculus.Traditional tcm therapy is that to take calculus, lithodialysis be aim, by adjusting the stagnation of QI of liver, gallbladder, kidney etc., and be aided with body constitution conditioning and carry out Coryza Treated by Syndrome Differentiation, but generally the course for the treatment of of this therapy long, formula complexity, curative effect is not remarkable.
In prior art, Chinese patent literature CN1165662A discloses a kind of Chinese medicine composition that comprises Herba clerodendranthi spicati, Lysimachia christinae Hance, Endothelium corneum Anas domestica, Aleuritopteris argentea (Gmel.) Fee, Rhizoma Polygoni Cuspidati, Huang Zaigen, Rhizoma Corydalis, Radix Curcumae, hair Xiucai, Herba Clerodendri fortunati, monkey hair, Herba Leonuri, Caulis Lonicerae, the Radix Linderae, Rhizoma Curcumae Longae and Radix Salviae Miltiorrhizae, the effect that it has depressed liver-energy dispersing and function of gallbladder promoting, removing damp-heat, antiinflammatory, softening the hard mass fossil, calculus, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain and improves bile component.But said composition formula is complicated, needs 16 kinds of mutual compatibilities of raw material of Chinese medicine medicine, Synergistic treatment.
Summary of the invention
Technical problem to be solved by this invention is the problem that Chinese medicine composition composition formula is complicated, treatment cost is high that is used for the treatment of calculus in prior art, provide that a kind of formula is simple, treatment cost is low, liver, gallbladder, kidney, lithangiuria are there is to Chinese medicine composition and the preparation method of good efficacy.
The invention provides a kind of Chinese medicine composition, the weight portion of said composition crude drug is: Rhizoma Polygoni Cuspidati 1-20 part, gold leaf Lysimachia christinae Hance 3-18 part, Herba Centellae 5-20 part, Radix Rubi parvifolii 1-15 part.
The weight portion of preferred feedstock medicine of the present invention is: Rhizoma Polygoni Cuspidati 5-15 part, gold leaf Lysimachia christinae Hance 6-12 part, Herba Centellae 10-15 part, Radix Rubi parvifolii 5-11 part.
The weight portion of optimum feed stock medicine of the present invention is: 10 parts of Rhizoma Polygoni Cuspidati, 11 parts of gold leaf Lysimachia christinae Hance, 12 parts of Herba Centellaes, 8 parts of Radix Rubi parvifolii.
Crude drug described in Chinese medicine composition of the present invention also has: 7 parts of Radix Bupleuri, 5 parts of Rhizoma Et Radix Notopterygiis.
Described Rhizoma Polygoni Cuspidati is wild Rhizoma Polygoni Cuspidati.
Described Chinese medicine composition is made into any peroral dosage form.
Described Chinese medicine composition is made into oral liquid, electuary or capsule.
The preparation method that the invention still further relates to described Chinese medicine composition, comprises the steps:
A) get Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii and clean respectively, dry;
B) the above-mentioned medicine that dries is risen with bundle, water decocts or boiled water soaks
The time that in described step b), water decocts or boiled water soaks is more than 5min.
The invention still further relates to the purposes of described Chinese medicine composition in preparation treatment liver, gallbladder, kidney, lithangiuria medicine.
Theory of Chinese medical science thinks that calculus is because of retention of damp-heat in the interior, accumulates into stone in the course of time and causes a disease, so the principle of Chinese traditional treatment calculus is mainly clearing away heat-damp and promoting diuresis, and blood stasis dispelling, calculus lithodialysis.
Rhizoma Polygoni Cuspidati is dry rhizome and the root of polygonaceae plant Rhizoma Polygoni Cuspidati Polygonum cuspidatum Sieb.et Zucc., cold nature, and mildly bitter flavor, returns liver, gallbladder, lung meridian, the effect of tool heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy; Gold leaf Lysimachia christinae Hance, formal name used at school Lysimachia nummularia ' Aurea ', warm in nature, acrid in the mouth, sweet, returns liver, gallbladder, kidney, urinary bladder channel, the effect of tool heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dampness removing jaundice eliminating; Herba Centellae has another name called Herba Lysimachiae, for dry herb or the whole herb with root of dicotyledon Umbelliferae Umbelliferae Herba Centellae Centella asiatica (L.) Urban, cold in nature, acrid in the mouth, hardship, return liver,spleen,kidney warp, the effect of tool clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling; Radix Rubi parvifolii has another name called radix rubi parvifol, cool in nature, and sweet-bitter flavor is returned liver, lung, kidney channel, the effect of tool heat clearing away solution, expelling wind and removing dampness.
Above four Chinese medicine fit applications, plays clearing away heat-damp and promoting diuresis altogether, blood stasis dispelling, and the effect of calculus lithodialysis, has good efficacy to liver, gallbladder, kidney, lithangiuria.
Radix Bupleuri cold nature, bitter in the mouth, pungent, returns Liver Channel, lung meridian, spleen channel, and tool expelling pathogenic factors from the exterior expels the heat-evil, the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, Rhizoma Et Radix Notopterygii is warm in nature, and acrid in the mouth, hardship are returned urinary bladder channel, kidney channel, the effect of tool wind-damp dispelling, pain relieving, belongs to wind medicine together with Radix Bupleuri, reaches yang invigorating, wet, the loose fire of victory, soothing the liver effect.Radix Bupleuri, Rhizoma Et Radix Notopterygii and Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii compatibility, at clearing away heat-damp and promoting diuresis, blood stasis dispelling, on the basis of calculus lithodialysis, further recovers function and coordinates, and reaches the object for the treatment of both the principal and secondary aspects of a disease.
The present invention has following advantage:
It is raw material that the present invention selects Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii, plays altogether clearing away heat-damp and promoting diuresis, blood stasis dispelling, and the effect of calculus lithodialysis, all has good efficacy to liver, gallbladder, kidney, lithangiuria.This formula is simple, and crude drug is cheap and easy to get, and treatment cost is low, has overcome the problem that Chinese medicine composition composition formula is complicated, treatment cost is high that is used for the treatment of calculus in prior art.With wind medicine Radix Bupleuri, Rhizoma Et Radix Notopterygii compatibility, on the basis for the treatment of calculus, further recover function and coordinate, reach the object for the treatment of both the principal and secondary aspects of a disease.
The specific embodiment
embodiment 1
Take Rhizoma Polygoni Cuspidati 1g, gold leaf Lysimachia christinae Hance 3g, Herba Centellae 5g, Radix Rubi parvifolii 1g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, with 500ml boiled water, soak 5min and can take.
embodiment 2
Take Rhizoma Polygoni Cuspidati 20g, gold leaf Lysimachia christinae Hance 18g, Herba Centellae 20g, Radix Rubi parvifolii 15g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, with 1500ml boiled water, soak 5min and can take.
embodiment 3
Take Rhizoma Polygoni Cuspidati 10g, gold leaf Lysimachia christinae Hance 11g, Herba Centellae 12g, Radix Rubi parvifolii 8g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, with 1000ml boiled water, soak 5min and can take.
embodiment 4
Take Rhizoma Polygoni Cuspidati 5g, gold leaf Lysimachia christinae Hance 6g, Herba Centellae 10g, Radix Rubi parvifolii 5g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, with 800ml boiled water, soak 10min and can take.
embodiment 5
Take Rhizoma Polygoni Cuspidati 15g, gold leaf Lysimachia christinae Hance 12g, Herba Centellae 15g, Radix Rubi parvifolii 8g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, with 1200ml boiled water, soak 8min and can take.
embodiment 6
Take Rhizoma Polygoni Cuspidati 20g, gold leaf Lysimachia christinae Hance 18g, Herba Centellae 20g, Radix Rubi parvifolii 15g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, add water 2000ml and decoct, boil after 5mi n, remove by filter residue and obtain extractum, powdered extract, prepares electuary.
embodiment 7
Take Rhizoma Polygoni Cuspidati 5g, gold leaf Lysimachia christinae Hance 6g, Herba Centellae 10g, Radix Rubi parvifolii 5g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, add water 1000ml and decoct, boil after 8mi n, remove by filter residue and obtain extractum, powdered extract, prepares capsule.
embodiment 8
Take Rhizoma Polygoni Cuspidati 12g, gold leaf Lysimachia christinae Hance 10g, Herba Centellae 12g, Radix Rubi parvifolii 9g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii are cleaned respectively, dried, with bundle, rise, add water 1500ml and decoct, boil after 10mi n, remove by filter residue and obtain extractum, powdered extract, prepares electuary.
embodiment 9
Take Rhizoma Polygoni Cuspidati 10g, gold leaf Lysimachia christinae Hance 11g, Herba Centellae 12g, Radix Rubi parvifolii 8g, Radix Bupleuri 7g, Rhizoma Et Radix Notopterygii 5g;
Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii, Radix Bupleuri, Rhizoma Et Radix Notopterygii are cleaned respectively, dried, with bundle, rise, with 1500ml boiled water, soak 10min and can take.
experimental example
In order to show the therapeutic effect of this Chinese medicine composition to calculus, the present invention is through 100 routine system clinical observations, hepatolithiasis patient 20 examples wherein, Patients with Cholelithiasis 30 examples, renal calculus patient's 20 examples, vesical calculus patient's 30 examples.In the process of above-mentioned clinical observation, and the work of above-mentioned patient being recorded to its medical history, the state of an illness, age and curative effect.
The criterion of clinical therapeutic efficacy is:
Clinical cure: transference cure, calculus is dissolved, and discharges, and x-ray or B ultrasonic check calculus disappear.
Effective: symptom is alleviated substantially, more than x-ray or B ultrasonic check calculus is partly discharged or calculus is dwindled or calculus position moves down 3cm.
Invalid: symptom is slightly alleviated, have no calculus and discharge, x-ray or B ultrasonic check calculus size, position are all without changing.
Medication is: give patient the oral liquid 100ml of oral embodiment 3 preparations.
The course for the treatment of: 15 days be a course for the treatment of, take every day twice.
Clinical experiment result shows, only uses this Chinese medicine composition of a course for the treatment of, and original symptom obviously alleviates.According to statistics, use after the course for the treatment of, reach 95% cure rate, 5% effective or improvement, without invalid situation (in Table 1).
Table 1
By above-mentioned same method, the oral liquid of embodiment 9 preparations is tested and shown, only use this Chinese medicine composition of a course for the treatment of, original symptom obviously alleviates.According to statistics, use after the course for the treatment of, reach 97% cure rate, 3% effective or improvement, without invalid situation (in Table 2).
Table 2
Contrast experiment's example
Take Herba clerodendranthi spicati 5g, Lysimachia christinae Hance 5g, Endothelium corneum Anas domestica 5g, Aleuritopteris argentea (Gmel.) Fee 5g, Rhizoma Polygoni Cuspidati 5g, yellow young root 5g, Rhizoma Corydalis 5g, Radix Curcumae 5g, hair Xiucai 5g, Herba Clerodendri fortunati 5g, monkey hair 5g, Herba Leonuri 5g, Caulis Lonicerae 5g, Radix Linderae 5g, Rhizoma Curcumae Longae 5g and Radix Salviae Miltiorrhizae 5g, according to the disclosed method of aforementioned Chinese patent literature CN1165662A, make oral liquid.Use this product to carry out clinic trial to 100 routine patients of identical body constitution, state of an illness state, medication is oral 100ml once, 2 times on the one.After successive administration 15 days, result is as shown in table 3, and its average cure rate only has 60%.
Table 3
Although the present invention elaborates it by above-mentioned specific embodiment; but; those skilled in the art should be understood that any form that does not exceed claim protection domain made on this basis and the variation of details, all belong to invention which is intended to be protected.
Claims (1)
1. a Chinese medicine composition that is used for the treatment of calculus, is characterized in that, the weight portion of said composition crude drug is: Rhizoma Polygoni Cuspidati 1-20 part, gold leaf Lysimachia christinae Hance 3-18 part, Herba Centellae 5-20 part, Radix Rubi parvifolii 1-15 part.
2. according to the Chinese medicine composition that is used for the treatment of calculus described in claim 1, it is characterized in that, the weight portion of described crude drug is: Rhizoma Polygoni Cuspidati 5-15 part, gold leaf Lysimachia christinae Hance 6-12 part, Herba Centellae 10-15 part, Radix Rubi parvifolii 5-11 part.
3. according to the Chinese medicine composition that is used for the treatment of calculus described in claim 2, it is characterized in that, the weight portion of described crude drug is: 10 parts of Rhizoma Polygoni Cuspidati, 11 parts of gold leaf Lysimachia christinae Hance, 12 parts of Herba Centellaes, 8 parts of Radix Rubi parvifolii.
4. according to the Chinese medicine composition that is used for the treatment of calculus described in claim 3, it is characterized in that, wherein said crude drug also has: 7 parts of Radix Bupleuri, 5 parts of Rhizoma Et Radix Notopterygiis.
5. according to the arbitrary described Chinese medicine composition that is used for the treatment of calculus of claim 1 to 4, it is characterized in that, described Rhizoma Polygoni Cuspidati is wild Rhizoma Polygoni Cuspidati.
6. according to the arbitrary described Chinese medicine composition that is used for the treatment of calculus of claim 1 to 4, it is characterized in that, described Chinese medicine composition is made into any peroral dosage form.
7. according to the Chinese medicine composition that is used for the treatment of calculus described in claim 6, it is characterized in that, described Chinese medicine composition is made into oral liquid, electuary or capsule.
8. the preparation method of the Chinese medicine composition that is used for the treatment of calculus described in claim 6, comprises the steps:
A) get Rhizoma Polygoni Cuspidati, gold leaf Lysimachia christinae Hance, Herba Centellae, Radix Rubi parvifolii and clean respectively, dry;
B) the above-mentioned medicine that dries is risen with bundle, water decocts or boiled water soaks.
9. the preparation method of the described Chinese medicine composition that is used for the treatment of calculus according to Claim 8, is characterized in that described step b) in water decocts or boiled water soaks time be more than 5min.
10. the purposes of the Chinese medicine composition that claim 1 to 4 is used for the treatment of calculus described in arbitrary in preparation treatment liver, gallbladder, kidney, lithangiuria medicine.
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| CN104740399A (en) * | 2015-04-09 | 2015-07-01 | 张�杰 | Traditional Chinese medicine medicament for preventing and treating urinary calculi and preparation method of traditional Chinese medicine medicament |
| CN107617067A (en) * | 2017-09-29 | 2018-01-23 | 梁正文 | It is a kind of be used for treat calculus lower stone dissipate and preparation method thereof |
| CN113750169A (en) * | 2021-07-19 | 2021-12-07 | 浙江羲和时光科技有限公司 | Chinese herbal medicine formula for preventing epidemic liver warm disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102258651A (en) * | 2010-05-26 | 2011-11-30 | 刘国昌 | Traditional Chinese medicine for treating gallstones |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102258651A (en) * | 2010-05-26 | 2011-11-30 | 刘国昌 | Traditional Chinese medicine for treating gallstones |
Non-Patent Citations (2)
| Title |
|---|
| 中医药治疗泌尿系结石临床研究进展;周向文等;《亚太传统医药》;20110430;第7卷(第4期);151-152 * |
| 周向文等.中医药治疗泌尿系结石临床研究进展.《亚太传统医药》.2011,第7卷(第4期),151-152. |
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