CN102119994B - Traditional Chinese medicine enema for treating exogenous fever of infants - Google Patents
Traditional Chinese medicine enema for treating exogenous fever of infants Download PDFInfo
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- CN102119994B CN102119994B CN2010100042241A CN201010004224A CN102119994B CN 102119994 B CN102119994 B CN 102119994B CN 2010100042241 A CN2010100042241 A CN 2010100042241A CN 201010004224 A CN201010004224 A CN 201010004224A CN 102119994 B CN102119994 B CN 102119994B
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Abstract
The invention relates to the technical field of a traditional Chinese medicine preparation, and discloses a traditional Chinese medicine enema for treating exogenous fever of infants. The enema is prepared by taking radix scutellariae, honeysuckle, forsythia, dandelion, gypsum and rhizoma anemarrhenae as raw materials through the steps of soaking, decocting and filtering. The invention is characterized in that each dose of enema is prepared from the following raw materials in proportioning by weight: 2-5g of radix scutellariae, 5-8g of honeysuckle, 2-5g of forsythia, 5-8g of dandelion, 9-12g of gypsum and 2-5g of rhizoma anemarrhenae. The enema has the functions of clearing away heat and toxic material, diminishing inflammation and allaying the fever, and is a preferred medicament for allaying the exogenous fever of infants. Compared with the existing treatment method, the enema disclosed by the invention can be quickly absorbed through rectal administration, has a good treatment effect, reduces the 'first pass effect' of general medicaments, has high bioavailability and low price, is convenient and easy to implement, does not have toxic side effects, has an obvious effect on allaying the fever, and also solves the problem that infants are afraid of needles and medicaments. Observed by 200 clinical cases, the antipyretic effective rate within 36 hours is 100%.
Description
Technical field
The present invention relates to the Chinese medicine preparation technical field, a kind of specifically treatment infantile fever caused by exogenous pathogens, the Chinese medicinal herbs decoction that effect is very ideal.
Background technology
Infantile common cold and upper respiratory tract infection are the commonly encountered diseases of department of pediatrics, and frequently-occurring disease is caused by virus usually, and symptoms such as heating, pharyngalgia, cough are often arranged, and bring misery to infant.
Children's's physiological and pathological feature: children's's internal organs are tender and lovely, and shape gas does not fill, and adding cold warm can not the self-care, and newborn food can not be from joint, in case nurse inappropriately, then are prone to hindered by pathogenic factor, so morbidity easily on the pathology.Children's is the body of " pure sun ", and sun is long has a surplus, in case ill, pathogenic factor is prone to heat being transformed from excessive YANG, is prone to sensible heat disease, so the heating of clinical diseases caused by exogenous pathogenic factor infant is more.Fever of children is prone to cause convulsions, dehydration, electrolyte disturbance and aggravates disease, and therefore, should take active and effective cooling measure to infantile fever caused by exogenous pathogens.The treatment infantile fever caused by exogenous pathogens has antipyretic-antalgic, antibiotic, antiviral class Drug therapy at present; But these medicines often produce side effect such as drug resistance, gastrointestinal reaction, hemopoietic system dysfunction, nephrotoxicity; Can produce serious anaphylactic shock like penicillin; Streptomycin, gentamycin can cause permanent deafness; Sulfonamides has inhibitory action to hemopoietic function, and antipyretic analgesic usually has side effect such as gastrointestinal reaction, hepatotoxicity and inhibition hemopoietic function, and is especially more unfavorable to weak sick child.Approach often adopts methods such as oral medication, intramuscular injection, venous transfusion, and 6 months to 4 years old child is prone to cry and scream during one's sickness; Uncooperative, often fear pin and be afraid of medicine, especially the oral medicine to bitter in the mouth causes reflex vomiting easily; Thereby compliance is poor; Mismatch treatment, often can not stop PD sometimes, influence the normal therapeutic effect.
Summary of the invention
To the defective that exists in the above-mentioned treatment, the object of the present invention is to provide a kind ofly according to Chinese medical theory, to take conveniently, operation is prone to row, cost, curative effect is high, the Chinese medicinal herbs decoction of treatment infantile fever caused by exogenous pathogens.This enema fully absorbs through intestinal mucosa in rectum, and interference factor is few, and medicine is avoided losing activity because of the effect of gastrointestinal tract PH environment or digestive enzyme; Mucous membrane of rectum absorbs fast, and medicine can directly get into blood circulation, without liver circulation and liver biochemical metabolism process; Avoided " first pass effect " of liver, pharmacokinetics shows that the peak concentration of intestinal mucosa administration is higher 3～10 times than oral; Bioavailability is higher 5～9 times than oral, and is similar with intravenously administrable.Children's's intestinal tube adult that compares is long, and the digestion area is relatively large, and intestinal wall is thin, the mucosa rich blood vessel, and permeability is high, thus the obvious adult's height of absorbance, thereby can bring into play drug effect better.Medicine retention enema not only effective ingredient bioavailability is high, and the performance curative effect is strong, has eliminated the child simultaneously and has feared the feared state of mind that pin is afraid of medicine, and effect has directly been brought into play in the reflex vomiting of having avoided oral amara to cause again, is worth clinical application
Technical scheme of the present invention
A kind of Chinese medicinal herbs decoction of treating infantile fever caused by exogenous pathogens: adopting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Gypsum Fibrosum, the Rhizoma Anemarrhenae is raw material, through soaking, decocts, and filters and processes enema.It is characterized in that every dose of raw material weight proportioning is:
Radix Scutellariae 2-5 gram Flos Lonicerae 5-8 gram Fructus Forsythiae 2-5 gram
Herba Taraxaci 5-8 gram Gypsum Fibrosum 9-12 gram Rhizoma Anemarrhenae 2-5 gram
A kind of Chinese medicinal herbs decoction of treating infantile fever caused by exogenous pathogens: adopting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Gypsum Fibrosum, the Rhizoma Anemarrhenae is raw material, it is characterized in that every dose of raw material preferred weight proportioning is:,
Radix Scutellariae 3 gram Flos Loniceraes 6 gram Fructus Forsythiaes 3 grams
The Herba Taraxaci 6 gram Gypsum Fibrosum 10 gram Rhizoma Anemarrhenaes 3 grams
Above-mentioned raw materials decocts through soaking, and filters and processes enema
The invention has the beneficial effects as follows:
The present invention has heat-clearing and toxic substances removing, the effect of the arresting convulsion of inducing sweat, and it is rapid-action that patient's coloclysis is used the back, has no side effect, and is applicable to wind-heat invading the lung and the heating, cough, the upper respiratory tract infection of pharyngalgia and the fever of children disease due to the influenza that cause.Observe 12 hours effective percentage of bringing down a fever effective percentage effective percentage 100% of bringing down a fever in 95%, 36 hour of bringing down a fever in 85%, 24 hour through clinical treatment 200 exception sense heating sick children.
Various drug effects are following among the present invention:
Effects such as the Radix Scutellariae nature and flavor are bitter, cold, go into the heart, lung, gallbladder, large intestine channel, and merit is apt to clear part of the body cavity above the diaphragm housing the heart and lungs lung-heat, has heat clearing and damp drying, and eliminating fire and detoxication stops blooding, and is antiabortive.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Modern pharmacological research shows: the rat fever that (1) Caulis et Folium Scutellariae total flavones causes dry yeast has significant refrigeration function, and baicalin abdominal cavity or intravenous injection also have tangible refrigeration function to the heating rat, and are certain amount-result relation.(2) Radix Scutellariae is antibiotic, the antiviral scope is wider, and external have inhibitory action to multiple gram positive bacteria, gram-negative bacteria, and influenza virus and hepatitis B virus are had inhibitory action; (3) in addition multiple pathogenic dermatophytes also there is certain inhibitory action.Antibiotic effective ingredient is baicalin and wogonoside unit.
The Flos Lonicerae nature and flavor are sweet, cold, go into lung, stomach warp, have another name called Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae etc., are described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property is sweet cold, gas fragrance, and clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance reaches thoroughly and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, and also kind removing summer-heat blood poison is used for various febrile diseases, and like fever of the body, dermexanthesis, send out cards such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, effect is all showing.Modern pharmacological research shows: (1) Flos Lonicerae has the antibiotic and antivirus action of broad-spectrum, promptly staphylococcus aureus, Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae, bacillus pyocyaneus and influenza virus etc. is all had obvious inhibitory action.(2) function of enhance immunity is arranged.Flos Lonicerae can promote lymphocyte transformation, strengthens leukocytic phagocytic function.(3) antiinflammatory, analgesic.Flos Lonicerae can promote the release of adrenocortical hormone, and inflammation is had obvious inhibitory action.
The Fructus Forsythiae nature and flavor are bitter, be slightly cold, and go into the heart, lung, gallbladder meridian, be longer than clearing away heart-fire, the part of the body cavity above the diaphragm housing the heart and lungs phoenix heat of loosing, and have heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, effects such as dispelling wind and heat pathogens.Modern pharmacological research shows: Fructus Forsythiae has broad-spectrum antibacterial action, and staphylococcus aureus, Hayes dysentery bacterium are had very strong inhibitory action, and other pathogenic bacterium, influenza virus, fungus are all had certain inhibitory action.
The Herba Taraxaci nature and flavor are bitter, sweet, cold, go into liver, stomach warp, have heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, the treating stranguria effect of dampness removing.Modern pharmacological research shows: Herba Taraxaci has stronger bactericidal action to staphylococcus aureus Resistant strain, Hemolytic streptococcus; To Diplococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi etc. and micrococcus catarrhalis also have certain bactericidal action.
The Gypsum Fibrosum nature and flavor are hot, sweet, go into lung, stomach warp, and kind clearing away lung-heat rushes down stomach-fire, has expelling pathogenic factors from muscles for clearing heat, the relieving restlessness effect of quenching the thirst.Be used for fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, lung-heat cough with asthma, the high Sheng of stomach-fire, headache toothache.The Gypsum Fibrosum main component is a hydrous calcium sulfate.Ferrum, magnesium etc. that a small amount of silicic acid, aluminium hydroxide, sulfide and trace are still arranged in addition.Modern pharmacological research shows: can suppress thermotaxic centre, alleviate skeletal muscle irritability, reduce vascular permeability, effects such as analgesic, spasmolytic, antiinflammatory are arranged.
Rhizoma Anemarrhenae nature and flavor are bitter, sweet, cold, go into lung, stomach, kidney channel, the effect that has clearing away heat-fire, promotes the production of body fluid and moisturize.Modern pharmacological research shows: (1) resisting pathogenic microbes in vitro tests shows that the Rhizoma Anemarrhenae has certain inhibitory action to Bacillus typhi, dysentery bacterium, diphtheria corynebacterium, staphylococcus aureus, Diplococcus pneumoniae etc.Extracts such as Rhizoma Anemarrhenae ethanol, ether have stronger inhibitory action to tubercule bacillus H37RV.The Rhizoma Anemarrhenae also has inhibitory action in various degree to some pathogenic dermatophytes and Candida albicans.Isomangiferin and chimonin all have significant anti-herpes simplex virus effect.(2) the analgesic Rhizoma Anemarrhenae has tangible prevention and therapeutical effect to the rabbit hyperpyrexia due to the escherichia coli.
The specific embodiment
The present invention treats the Chinese medicinal herbs decoction of infantile fever caused by exogenous pathogens, and every dose takes by weighing raw material of Chinese medicine by following weight
Radix Scutellariae 3 gram Flos Loniceraes 6 gram Fructus Forsythiaes 3 grams
The Herba Taraxaci 6 gram Gypsum Fibrosum 10 gram Rhizoma Anemarrhenaes 3 grams
Soaked above-mentioned mixed material 30 minutes with clear water 200ml, the Gypsum Fibrosum 20 minutes of being decocted first is fried in shallow oil altogether with other medicine and was got filtrate in 15 minutes, and multiple slag decocts once again, and twice filtrate merges and be concentrated into 30ml.(12 hours 1 time) retention enema at twice; Treat to make infant get lateral position about medicine temperature 35 degree, insert anus 5-10cm with children's's anal canal and slowly pour into colon, the row retention enema from anal canal with 20ml syringe absorption medicinal liquid 15ml; Flat the crouching of bed hedgehopping buttocks absorbs medicinal liquid fully after the coloclysis, every day potion.
Claims (2)
1. Chinese medicinal herbs decoction of treating infantile fever caused by exogenous pathogens, adopting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Gypsum Fibrosum, the Rhizoma Anemarrhenae is raw material, through soaking, decocts, filtration forms, and it is characterized in that the weight proportion of every dose of raw material is:
Radix Scutellariae 2-5 gram Flos Lonicerae 5-8 gram Fructus Forsythiae 2-5 gram
Herba Taraxaci 5-8 gram Gypsum Fibrosum 9-12 gram Rhizoma Anemarrhenae 2-5 gram.
2. Chinese medicinal herbs decoction of treating infantile fever caused by exogenous pathogens, adopting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Gypsum Fibrosum, the Rhizoma Anemarrhenae is raw material, through soaking, decocts, filtration forms, and it is characterized in that every dose of raw material weight proportioning is:
Radix Scutellariae 3 gram Flos Loniceraes 6 gram Fructus Forsythiaes 3 grams
The Herba Taraxaci 6 gram Gypsum Fibrosum 10 gram Rhizoma Anemarrhenaes 3 grams.
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| CN105079520A (en) * | 2014-05-13 | 2015-11-25 | 重庆美德实业集团有限公司 | Traditional Chinese medicine powder used for improving sub-health state of swinery and preparation process thereof |
| CN105616518A (en) * | 2014-11-18 | 2016-06-01 | 郝建友 | Injection for treating epidemic cerebrospinal meningitis |
| CN104306679A (en) * | 2014-11-18 | 2015-01-28 | 郝建友 | Chinese herb agentia for treating epidemic cerebrospinal meningitis and preparation method thereof |
| CN115364148A (en) * | 2021-05-20 | 2022-11-22 | 林鹤 | Enema |
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| CN1883651A (en) * | 2006-05-24 | 2006-12-27 | 佛山冯了性药业有限公司 | Chinese medicinal composition for treating wind-heat cold and preparation method thereof |
| CN101264233A (en) * | 2008-04-25 | 2008-09-17 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating lobar pneumonia and preparation thereof |
| CN101543602A (en) * | 2008-03-28 | 2009-09-30 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for treating upper respiratory tract infection and preparation method thereof |
| CN101601830A (en) * | 2009-07-10 | 2009-12-16 | 卢速江 | A kind of Chinese medicine preparation for the treatment of flu and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1883651A (en) * | 2006-05-24 | 2006-12-27 | 佛山冯了性药业有限公司 | Chinese medicinal composition for treating wind-heat cold and preparation method thereof |
| CN101543602A (en) * | 2008-03-28 | 2009-09-30 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for treating upper respiratory tract infection and preparation method thereof |
| CN101264233A (en) * | 2008-04-25 | 2008-09-17 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating lobar pneumonia and preparation thereof |
| CN101601830A (en) * | 2009-07-10 | 2009-12-16 | 卢速江 | A kind of Chinese medicine preparation for the treatment of flu and preparation method thereof |
Non-Patent Citations (1)
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