CN101264233A - Chinese medicinal composition for treating lobar pneumonia and preparation thereof - Google Patents

Chinese medicinal composition for treating lobar pneumonia and preparation thereof Download PDF

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Publication number
CN101264233A
CN101264233A CNA2008101050604A CN200810105060A CN101264233A CN 101264233 A CN101264233 A CN 101264233A CN A2008101050604 A CNA2008101050604 A CN A2008101050604A CN 200810105060 A CN200810105060 A CN 200810105060A CN 101264233 A CN101264233 A CN 101264233A
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parts
herba
medicine composition
radix
chinese medicine
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何俊保
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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Abstract

The invention relates to a Chinese herbal medicine composition which is used for treating lobar pneumonia. The Chinese herbal medicine composition comprises dayflower, baical skullcap, honeysuckle, peucedanum decursiva, herba patriniae, weeping forsythia, flatland wood, mulberry leaves, houttuyinie en Coeur, anemarrhena asphodeloides bunge, dandelion, lilyturf root, cidcada slough, giant knotweed, almond, plaster stone and/or carriers accepted by pharmacy. The invention also relates to a preparation method of the Chinese herbal medicine composition. The invention has the advantages of clearing away heat and toxic material, activating blood circulation to dissipate blood stasis and eliminating sputum and relieving coughs, applicable for curing the symptoms of chilling shiver, fever heat, chest pain and coughs caused by the lobar pneumonia.

Description

A kind of Chinese medicine composition for the treatment of lobar pneumonia and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of Chinese medicine composition for the treatment of lobar pneumonia and preparation method thereof.
Background technology
Lobar pneumonia (lobar pneumonia) is caused that by streptococcus pneumoniae infection pathological changes originates in alveolar, and extends to the fibrinous inflammation of the lung of whole or a plurality of Da Ye rapidly.Pathological changes is often invaded the major part of a leaf or a leaf of lung, can involve 2-3 the lobe of the lung when pathological changes is serious, and is generally common with the bottom right lung.Between twenty and fifty patient sees more, good sending out in winter and spring.Approximately through 5~10 days, body temperature descended, resolution of symptoms.Lobar pneumonia more than 95% is caused by streptococcus pneumoniae, and is the strongest with III type person virulence especially.In addition, pneumobacillus, staphylococcus aureus, Hemolytic streptococcus, hemophilus influenza also can cause.The inducement that catch cold, tired, drunk, flu, anesthesia, diabetes, liver, kidney disease etc. all can be pneumonia.At this moment, the defense function of respiratory tract is weakened, and Abwehrkraft des Koepers reduces, and bacterial infection easily takes place.Antibacterial breeds after invading alveolar therein, particularly the serous effusion of Xing Chenging helps bacterial reproduction again, and antibacterial is spread rapidly to contiguous lung tissue by interalveolar pores or alveolar bronchiole, thereby involve whole Da Ye, between Da Ye, spread then frenulum bacterium transudate due to the leaf bronchogenic spread.
The cardinal symptom of lobar pneumonia has:
1. onset is hurried, shiver with cold, hyperpyrexia, chest pain, coughs, coughs rusty expectoration.The extensive person of pathological changes can accompany tachypnea and cyanosis.
2. some cases has nauseating, vomiting, abdominal distention, diarrhoea.
3. serious symptom person can have neural mental symptom, as dysphoria, delirium etc.Also loop depletion on every side can take place, the accompanying infection shock claims shock type (or toxic) pneumonia.
4. face of acute ill, rapid breathing, flaring of alaenasi.
5. early stage pulmonary sign is not obvious or only have respiratory murmur to lower and pleuritic rub.Can there be typical sign the consolidation phase, and respiratory movement weakens as Ipsilateral, and vocal fremitus strengthens, dull percussion note, and the auscultation respiratory murmur lowers, and moist rale or pathologic bronchial breathing sound are arranged.
Lobar pneumonia is that bacterial pneumonia is modal.Most prognosis bonas, but through many rehabilitations about 2 weeks of treatment rationally.But old, original chronic disease, the concurrent shock person's prognosis that is in a bad way are relatively poor.Therefore must note prevention upper respiratory tract infection, strengthen cold resistant training; The inducement such as catch cold, drunk, overtired of avoiding drenching with rain; Cure the Primary Disease as chronic heart and lung diseases, chronic hepatopathy, diabetes and pars oralis pharyngis disease etc., can prevent the generation of pneumonia.
The traditional Chinese medical science thinks that lobar pneumonia belongs to " pathogenic wind-warm " " pulmonary distension " category.Primary disease is many suffers from cold and drenches with rain because of the imbalance of human body cold and heat, or the daily life impermanence, and when overtired, healthy energy is impaired, weakened defensive QI, and the heresy of pathogenic wind-warm is violated lung in an opponent's defence and is fallen ill." epidemic febrile disease longitude and latitude " pointed out: " warm pathogen tend to attack the upper orifices, attacking the lung first ".Attack outward from the beginning of pathogenic wind-warm, the evil lung of violating is defended, and defends stagnation of QI resistance, Lung Qi obstruction, thus see fever with aversion to cold, cough, lungs such as headache body Chu are defended sign, and heat is gone into edema caused by disorder of QI then, and pyretic toxicity is stopped up lung, and impairment of dispersing and descending function of the lung is so see hyperpyrexia, cough with asthma, sweating, thirsty; The bright lung Tianjin of heat, refining liquid is expectorant, so the noise made in coughing or vomiting yellow sputum; Injury of blood vessel of the lung by heat, then noise made in coughing or vomiting rusty expectoration or sputum mixed with blood; Expectorant heat is handed over resistance, QI and blood retardance, then chest pain.If vital QI cannot conquer pathogen, excessive noxious heat is to pass nutrient blood, upsets the mind, light dysphoria then, palpitation and insomnia; Heavy then unconsciousness and delirium; Extreme heat causing wind syndrome is then twitched.Pathogenic heat are contained very much, and healthy energy is not propped up, and extreme cold of the limbs can occur, dripping sweat, faint pulse being about to disappear etc., the crisis of YIN and YANG exhausted simultaneously.If strong vital QI leading to retreat of pathogen, the expectorant pyretolysis then spiritlessness and weakness, feverish sensation in the palms and soles, the time of impairment of both QI and YIN such as thready and rapid pulse can occur.
The traditional Chinese medical science adopts this disease of decoction for the treatment of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of lobar pneumonia.
The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of lobar pneumonia, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:
Herba Commelinae 5-10 part Radix Scutellariae 20-30 part Flos Lonicerae 15-25 part
Radix Peucedani 10-20 part Herba Patriniae 10-15 part Fructus Forsythiae 15-25 part
PINGDIMU 10-20 part Folium Mori 5-15 part Herba Houttuyniae 10-15 part
Rhizoma Anemarrhenae 5-15 part Herba Taraxaci 10-20 part 10-15 Radix Ophiopogonis part
Periostracum Cicadae 10-15 part Rhizoma Polygoni Cuspidati 5-10 part Semen Armeniacae Amarum 20-30 part
Gypsum Fibrosum 10-20 part
Effective ingredient is preferably made by weight by following raw materials according:
21 parts of 26 portions of Flos Loniceraes of 8 parts of Radix Scutellariaes of Herba Commelinae
21 parts of 13 parts of Fructus Forsythiaes of 16 parts of Herba Patriniae of Radix Peucedani
13 parts of 11 parts of Herba Houttuyniae of 16 parts of Folium Mori of PINGDIMU
13 parts of 11 parts of Herba Taraxacis of the Rhizoma Anemarrhenae 16 parts of Radix Ophiopogonis
26 parts in 8 parts of Semen Armeniacae Amarums of 12 parts of Rhizoma Polygoni Cuspidati of Periostracum Cicadae
15 parts of Gypsum Fibrosum
The present invention also provides a kind of preparation method of this Chinese medicine composition, comprises the steps:
(1) to be broken into impalpable powder standby for Gypsum Fibrosum;
(2) Fructus Forsythiae, Folium Mori, the Rhizoma Anemarrhenae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae, Radix Scutellariae, Flos Lonicerae, Radix Peucedani, Herba Patriniae, PINGDIMU, Herba Houttuyniae, Herba Taraxaci, Radix Ophiopogonis, Periostracum Cicadae, Rhizoma Polygoni Cuspidati, Semen Armeniacae Amarum decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying
Be ground into fine powder, make granule, capsule, tablet and pill with pharmaceutically acceptable carrier.
Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet, pill oral administration is used.
Chinese medicine composition of the present invention has effects such as heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough, is used for diseases such as shiver with cold that lobar pneumonia causes, hyperpyrexia, chest pain, cough.
The specific embodiment
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: Chinese medicinal composition granules of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Fructus Forsythiae 210g, Folium Mori 110g, Rhizoma Anemarrhenae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae 80g, Radix Scutellariae 260g, Flos Lonicerae 210g, Radix Peucedani 160g, Herba Patriniae 130g, PINGDIMU 160g, Herba Houttuyniae 130g, Herba Taraxaci 160g, Radix Ophiopogonis, 130g, Periostracum Cicadae 120g, Rhizoma Polygoni Cuspidati 80g, Semen Armeniacae Amarum 260g decocted with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, add dextrin 800g, lactose 200g, mixing, with 75% ethanol wet granulation promptly.
Embodiment 2: Chinese medicinal composition capsules agent of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Fructus Forsythiae 210g, Folium Mori 110g, Rhizoma Anemarrhenae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae 80g, Radix Scutellariae 260g, Flos Lonicerae 210g, Radix Peucedani 160g, Herba Patriniae 130g, PINGDIMU 160g, Herba Houttuyniae 130g, Herba Taraxaci 160g, Radix Ophiopogonis, 130g, Periostracum Cicadae 120g, Rhizoma Polygoni Cuspidati 80g, Semen Armeniacae Amarum 260g decocted with water secondary, each 2 hours, filter merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, dry, be ground into fine powder, add dextrin 400g mixing, in the capsulae vacuus of packing into promptly.
Embodiment 3: Chinese medicine composition tablet of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Fructus Forsythiae 210g, Folium Mori 110g, Rhizoma Anemarrhenae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae 80g, Radix Scutellariae 260g, Flos Lonicerae 210g, Radix Peucedani 160g, Herba Patriniae 130g, PINGDIMU 160g, Herba Houttuyniae 130g, Herba Taraxaci 160g, Radix Ophiopogonis, 130g, Periostracum Cicadae 120g, Rhizoma Polygoni Cuspidati 80g, Semen Armeniacae Amarum 260g decocted with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, add starch 300g, carboxymethylstach sodium 30g is with 70% ethanol wet granulation, tabletting, coating are promptly.
Embodiment 4: Chinese medicine composition pill of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Fructus Forsythiae 210g, Folium Mori 110g, Rhizoma Anemarrhenae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae 80g, Radix Scutellariae 260g, Flos Lonicerae 210g, Radix Peucedani 160g, Herba Patriniae 130g, PINGDIMU 160g, Herba Houttuyniae 130g, Herba Taraxaci 160g, Radix Ophiopogonis, 130g, Periostracum Cicadae 120g, Rhizoma Polygoni Cuspidati 80g, Semen Armeniacae Amarum 260g decocted with water secondary, each 2 hours, filtered, merging filtrate, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, adds refined honey 40g and an amount of water, general ball is made water-honeyed pill.

Claims (4)

1, a kind of Chinese medicine composition for the treatment of lobar pneumonia is to be made by effective ingredient and/or pharmaceutically acceptable carrier, it is characterized in that described effective ingredient is made by weight by following raw materials according:
Herba Commelinae 5-10 part Radix Scutellariae 20-30 part Flos Lonicerae 15-25 part
Radix Peucedani 10-20 part Herba Patriniae 10-15 part Fructus Forsythiae 15-25 part
PINGDIMU 10-20 part Folium Mori 5-15 part Herba Houttuyniae 10-15 part
Rhizoma Anemarrhenae 5-15 part Herba Taraxaci 10-20 part 10-15 Radix Ophiopogonis part
Periostracum Cicadae 10-15 part Rhizoma Polygoni Cuspidati 5-10 part Semen Armeniacae Amarum 20-30 part
Gypsum Fibrosum 10-20 part
2, Chinese medicine composition as claimed in claim 1 is characterized in that described effective ingredient made by weight by following raw materials according:
21 parts of 26 portions of Flos Loniceraes of 8 parts of Radix Scutellariaes of Herba Commelinae
21 parts of 13 parts of Fructus Forsythiaes of 16 parts of Herba Patriniae of Radix Peucedani
13 parts of 11 parts of Herba Houttuyniae of 16 parts of Folium Mori of PINGDIMU
13 parts of 11 parts of Herba Taraxacis of the Rhizoma Anemarrhenae 16 parts of Radix Ophiopogonis
26 parts in 8 parts of Semen Armeniacae Amarums of 12 parts of Rhizoma Polygoni Cuspidati of Periostracum Cicadae
15 parts of Gypsum Fibrosum
3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule, tablet and pill as the arbitrary described Chinese medicine composition of claim 1-2.
4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:
(1) to be broken into impalpable powder standby for gypsum powder;
(2) Fructus Forsythiae, Folium Mori, the Rhizoma Anemarrhenae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Herba Commelinae, Radix Scutellariae, Flos Lonicerae, Radix Peucedani, Herba Patriniae, PINGDIMU, Herba Houttuyniae, Herba Taraxaci, Radix Ophiopogonis, Periostracum Cicadae, Rhizoma Polygoni Cuspidati, Semen Armeniacae Amarum decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, make granule, capsule, tablet and pill with pharmaceutically acceptable carrier.
CNA2008101050604A 2008-04-25 2008-04-25 Chinese medicinal composition for treating lobar pneumonia and preparation thereof Pending CN101264233A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102119994B (en) * 2010-01-12 2012-05-23 冯陆冰 Traditional Chinese medicine enema for treating exogenous fever of infants
CN102688427A (en) * 2012-05-08 2012-09-26 安徽智远生物科技有限公司 Chinese medicinal composition for treating pneumonia and preparation method thereof
CN102836373A (en) * 2012-09-19 2012-12-26 陈旭东 Medicament for treating infantile pneumonia
CN103055297A (en) * 2013-01-14 2013-04-24 吕冀 Traditional Chinese medicine mixture for treating infant lobar pneumonia
CN104096070A (en) * 2014-06-30 2014-10-15 无锡市崇安区科技创业服务中心 Traditional Chinese medical composition for treating cold, and preparation method thereof
CN104398938A (en) * 2014-11-19 2015-03-11 杨光霞 Traditional Chinese medicine for treating wind-heat invading lung lobar pneumonia and preparation method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102119994B (en) * 2010-01-12 2012-05-23 冯陆冰 Traditional Chinese medicine enema for treating exogenous fever of infants
CN102688427A (en) * 2012-05-08 2012-09-26 安徽智远生物科技有限公司 Chinese medicinal composition for treating pneumonia and preparation method thereof
CN102688427B (en) * 2012-05-08 2014-07-09 安徽智远生物科技有限公司 Chinese medicinal composition for treating pneumonia and preparation method thereof
CN102836373A (en) * 2012-09-19 2012-12-26 陈旭东 Medicament for treating infantile pneumonia
CN103055297A (en) * 2013-01-14 2013-04-24 吕冀 Traditional Chinese medicine mixture for treating infant lobar pneumonia
CN104096070A (en) * 2014-06-30 2014-10-15 无锡市崇安区科技创业服务中心 Traditional Chinese medical composition for treating cold, and preparation method thereof
CN104398938A (en) * 2014-11-19 2015-03-11 杨光霞 Traditional Chinese medicine for treating wind-heat invading lung lobar pneumonia and preparation method

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Open date: 20080917