CN101874880B - Method for preparing traditional Chinese medicine for treating pediatric wind-heat lung obstruction type pneumonia asthma - Google Patents

Method for preparing traditional Chinese medicine for treating pediatric wind-heat lung obstruction type pneumonia asthma Download PDF

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CN101874880B
CN101874880B CN2010102037002A CN201010203700A CN101874880B CN 101874880 B CN101874880 B CN 101874880B CN 2010102037002 A CN2010102037002 A CN 2010102037002A CN 201010203700 A CN201010203700 A CN 201010203700A CN 101874880 B CN101874880 B CN 101874880B
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CN101874880A (en
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顾玉栋
闫向东
李金龙
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Abstract

The invention relates to a method for preparing a traditional Chinese medicine for treating pediatric wind-heat lung obstruction type pneumonia asthma, and belongs to the technical field of the preparation method of traditional Chinese medicines. At present, the pediatric wind-heat lung obstruction type pneumonia asthma is treated by adopting sulfa and antibiotics generally, but patients who adopt sulfamethoxazole have the symptoms of gastrointestinal reactions, crystalluria, hematuria, tetter, medicinal fever and oligoleukocythemia. The invention adopts the technical scheme that: the method comprises the steps of immersing 25 medicaments of ephedra, apricot kernel, gypsum, simpleleaf shrub chastetree fruit, cicada slough, fermented soybean, folium mori, flos chrysanthemum, radix asteris,common coltsfoot flower, ginkgo seed, purple perilla, honeysuckle, weeping forsythia, indigowoad leaf, indigowoad root, dahurian patrinia herb, houttuynia cordata thumb, Chinese olive, vietnamese sophora root, franchet groundcherry calyx and fruit, reed rhizome, folium phyllostachytis, platycodon root and liquorice root into water, decocting the medicaments over slow fire, and filtering and removing decoction dregs to obtain decocted decoction, namely the traditional Chinese medicine for treating the pediatric wind-heat lung obstruction type pneumonia asthma. The traditional Chinese medicine has the advantages of simple preparation, small toxic and side effect of the prepared Chinese medicinal liquid, quick absorption in digestive tracts, easy absorption, short course of treatment and high cure rate.

Description

A kind of Chinese medicinal preparation method for the treatment of pediatric wind-heat lung obstruction type pneumonia asthma
Technical field
The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of pediatric wind-heat lung obstruction type pneumonia asthma more specifically.
Background technology
The treatment pediatric wind-heat lung obstruction type pneumonia asthma generally adopts sulfonamides and antibiotics at present.1. adopt the sulfamethoxazole patient to cause gastrointestinal reaction, crystalluria, hematuria, erythra, medicine heat and leukopenia sometimes.2. adopt penicillin: with before must do skin test, positive person forbidding.(the most dangerous anaphylactic shock can occur in and do tuerculoderma at that time because allergy, particularly anaphylactic shock easily take place penicillin, only a few can occur in the process of continuous use, the latter claims the Delayed Hypersensitivity shock), as untimely rescue, but threat to life.3. use the amoxicillin: accidental erythra can have nauseating, epigastric discomfort, diarrhoea, pseudomembranous colitis etc.4. use carbenicillin: various types of allergy can occur.Can cause neural poison reaction, pulmonary edema after heavy dose of administration; Can occur the transience transaminase during the medication raises and granulocytopenia.5. piperacillin: cause nausea, uncomfortable in chest, cough, heating, halitosis, conjunctival congestion etc. allergy such as erythra, gargalesthesia, dizziness, numbness, heating etc. easily.6. use aminophylline: have reactions such as nauseating, vomiting, inappetence, stomach discomfort, insomnia, increased heart rate, can cause tachycardia, cardiac arrhythmia, frightened Jue, blood pressure rapid drawdown during the too fast or excessive concentration of intravenously administrable, in addition dead.
Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of pediatric wind-heat lung obstruction type pneumonia asthma.Pulmonary type breathes heavily that to cough be one of common lung pattern disease in children's period, and children's's lungs are tender and lovely, and shape gas does not fill, weakened defensive QI, and the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, exopathogen is gone into by mouth and nose or fur, invades lung to defend, and impaired depurative descending of lung QI, lung qi closing are sent out to pneumonia asthma and are coughed.Lid is because of lung governing qi, and department breathes, and closes fur outward, the gas of main the whole body, and regulating fluid apssage, following defeated bladder is source on the water.Its property is reduced to suitable with Xuan Fasu, strongly fragrant in lung if pathogen is closed, and lung loses respectful the falling of clear a surname, and water liquid defeatedization had no right, and is expectorant with fixed attention then, and the expectorant lung network that stagnates hinders in air flue, so that abnormal rising of lung-QI, for coughing to breathing heavily gurgling with sputum; If the exopathogen invading the interior heat-transformation, pathogenic heat is flourishing, and Tianjin refining liquid that burns becomes expectorant, and gluing of phlegm and heat is stopped up in air flue, and expectorant is with QI rising in reverse order, and then high fever is thirsty, breathes heavily the excessive phlegm of coughing, and wheezing sound in the throat is filtered.Thereby occur based on the pneumonia asthma of lung qi obturations such as cough, asthma, rale, flaring of nares, the heating syndrome of coughing.The clinical manifestation of pediatric wind-heat lung obstruction type pneumonia asthma: lighter from the beginning of syndrome, visible fever and aversion to wind, it is out of breath to cough, abundant expectoration, the thick glutinous yellow skin of matter, thirsty, swallow red, red tongue, white or yellow thin fur, floating and rapid pulse.Heavily card is then seen the hyperpyrexia agitation, cough slight asthma, flaring of nares gurgling with sputum out of breath, flushing conjunctival congestion, constipation yellow urine, red tongue with yellow fur, slippery and rapid pulse.Blood test: total white blood cells increases; Neutrophilic leukocytosis; Lymphocytosis.
Its technical scheme is: get Herba Ephedrae 3 weight portions, Semen Armeniacae Amarum 3 weight portions, Gypsum Fibrosum 3 weight portions, Fructus Viticis 6 weight portions, Periostracum Cicadae 6 weight portions, Semen Sojae Preparatum 6 weight portions, Folium Mori 9 weight portions, Flos Chrysanthemi 9 weight portions, Radix Asteris 6 weight portions, Flos Farfarae 6 weight portions, Semen Ginkgo 3 weight portions, Fructus Perillae 6 weight portions, Flos Lonicerae 9 weight portions, Fructus Forsythiae 3 weight portions, Folium Isatidis 9 weight portions, Radix Isatidis 6 weight portions, Herba Patriniae 6 weight portions, Herba Houttuyniae 6 weight portions, Fructus Canarii albi 3 weight portions, Radix Sophorae Tonkinensis 3 weight portions, Calyx Seu Fructus Physalis 3 weight portions, Rhizoma Phragmitis 9 weight portions, Folium Bambusae 3 weight portions, Radix Platycodonis 6 weight portions and Radix Glycyrrhizae 6 weight portions, top 25 flavor medicines are put into 1000 ml waters together, soaked 30 minutes, slow fire is fried 30 minutes then, filter and remove residue gets 300 milliliters of medicinal liquids, and fried medicinal liquid is the Chinese medicine of treatment pediatric wind-heat lung obstruction type pneumonia asthma.
The advantage of this invention is: our 25 flavor Chinese medicines, all can buy in pharmacy, and to make simply, the herb liquid toxic and side effects of making is little, absorbs in digestive tract soon, absorbs short treating period, cure rate height easily.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine sulphonamides, antibiotics to cause.Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, it is MAXINGSHIGAN TANG that this 3 flavor medicine is joined Radix Glycyrrhizae, belongs to the agent of relieving cough and asthma, has Xin Liang and leads off, the effect of clearing lung, relieving asthma.Its epheday intermedia: hot, little hardship, temperature.Go into lung, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, diuretic detumescent.Modern medicine study thinks that Herba Ephedrae contains ephedrine, isoephedrine, Herba Ephedrae wet goods.Ephedrine has remarkable loose bronchial smooth muscle effect, can remove the dyspnea that causes because of tracheal smooth muscle spasm.Semen Armeniacae Amarum: be medicine for the treatment of cough and asthma.Bitter, hot, temperature, slightly poisonous.Go into lung, large intestine channel.Relieving cough and asthma, loosening bowel to relieve constipation, the Semen Armeniacae Amarum bitter in the mouth is hot and warm in nature, goes into the lung meridian edema caused by disorder of QI, and the special hardship of merit is let out profit and is fallen, and holds concurrently hot a surname to evacuate, and is good at the lung qi dispersing expectorant, moisturizes the therapeutic method to keep the adverse QI flowing downwards.Semen Armeniacae Amarum has the effect of laxation relieving constipation, so be applicable to the dryness of the intestine constipation again owing to contain the oil profit.Gypsum Fibrosum: be heat clearing and fire purging medicine.Hot, sweet, Great Cold.Go into lung, stomach warp.Resolving heat and reducing pathogenic fire, relieving restlessness are quenched the thirst, promoting tissue regeneration and ulcer healing, the key medicine of dividing excess-heat for removing summer-heat lung gastric qi.Modern medicine study is thought: the composition of Gypsum Fibrosum is that hydrous calcium sulfate, Gypsum Fibrosum Preparatum are dead plaster.Zoopery proves that Gypsum Fibrosum has obvious antipyretic effect, and Gypsum Fibrosum is for oral administration through the gastric acid effect, become soluble calcium salt, be absorbed into blood after, to neural (comprising thermotaxic centre) and muscle inhibitory action being arranged, and can lower vascular permeability, thereby analgesic, spasmolytic and antiinflammation are arranged.Herba Ephedrae, Semen Armeniacae Amarum, this 3 flavor medicine of Gypsum Fibrosum play main therapeutical effect in the process of treatment pediatric wind-heat lung obstruction type pneumonia asthma disease, so be monarch drug.Fructus Viticis, Periostracum Cicadae, Semen Sojae Preparatum, Folium Mori, Flos Chrysanthemi, Radix Asteris, Flos Farfarae, Semen Ginkgo, Fructus Perillae, Flos Lonicerae, Fructus Forsythiae, Folium Isatidis, Radix Isatidis, Herba Patriniae, Herba Houttuyniae, Fructus Canarii albi, Radix Sophorae Tonkinensis, Calyx Seu Fructus Physalis, Rhizoma Phragmitis, Folium Bambusae, this 20 flavor medical instrument has expelling wind and clearing away heat, sore-throat relieving, relieving restlessness, nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, astringing lung QI for relieving asthma, heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds.Wherein Fructus Viticis, Periostracum Cicadae, Semen Sojae Preparatum, Folium Mori, this 5 flavor property of medicine of Flos Chrysanthemi are trembled with fear or are slightly cold, and have expelling wind and clearing away heat, the merit of sore-throat relieving relieving restlessness; Radix Asteris, Flos Farfarae, Semen Ginkgo, this 4 flavor medicine of Fructus Perillae are all gone into lung meridian, have nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, the merit of astringing lung QI for relieving asthma.Flos Lonicerae, Fructus Forsythiae, Folium Isatidis, Radix Isatidis, Herba Patriniae, Herba Houttuyniae, this 7 flavor medical instrument of Fructus Canarii albi have the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, secretion replenishing and throat moistening, the sweet cold clear virtue of Flos Lonicerae wherein, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance reach thoroughly and hold back heresy, can dispelling wind-heat, again can removing summer-heat blood poison.Modern medicine study confirms: Flos Lonicerae contains Saponin, tannic acid, inosite etc.Flos Lonicerae Saponin energy regulate body temperature maincenter has refrigeration function, and the effect of detoxifcation, antiinflammatory is arranged.The experiment in vitro proof has extensive antibacterial action: staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae, dysentery bacterium, Bacillus typhi etc. are all had stronger antibacterial action; Influenza virus there is certain inhibitory action; The Fructus Forsythiae and the eliminating stagnation of relieving inflammation or internal heat, all diseases of pyretic toxicity, normal and Flos Lonicerae mutual reinforcement between adapteds controlled; The double energy of Herba Taraxaci liver heat removing and eyesight improving; The cooling blood and dissolving purpura of the double energy of Folium Isatidis; The double energy of Radix Isatidis removing heat from blood; The evacuation of pus of the double energy of Herba Patriniae clots absorbing; The double energy of Herba Houttuyniae subduing inflammation, inducing diuresis for treating stranguria syndrome; Radix Sophorae Tonkinensis, Calyx Seu Fructus Physalis, Rhizoma Phragmitis, Folium Bambusae, this 4 flavor medical instrument has the merit of detumescence sore-throat relieving, clearing heat and relieving fidgetness.Fructus Viticis, Periostracum Cicadae, Semen Sojae Preparatum, Folium Mori, Flos Chrysanthemi, Radix Asteris, Flos Farfarae, Semen Ginkgo, Fructus Perillae, Flos Lonicerae, Fructus Forsythiae, Folium Isatidis, Radix Isatidis, Herba Patriniae, Herba Houttuyniae, Fructus Canarii albi, Radix Sophorae Tonkinensis, Calyx Seu Fructus Physalis, Rhizoma Phragmitis, Folium Bambusae, this 20 flavor medicine can be assisted principal agent performance therapeutical effect in the process of treatment pediatric wind-heat lung obstruction type pneumonia asthma disease, so be ministerial drug.Radix Platycodonis is lung meridian edema caused by disorder of QI medicine, specially goes into lung meridian.Toil is flat, both rises and falls, and is good at the dispersing and elevation lung qi, the fast diaphragm of a surname's breast, expelling phlegm for arresting cough.Can treat the disease of laryngopharynx swelling and pain.Be good at the dispersing and elevation lung qi, all medicines of rate are up, and through focus is so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate the toxicity of all medicines again, so be messenger drug.More than 25 flavor medicine compatibilities use, play Xin Liang jointly and lead off, clearing lung, relieving asthma, expelling wind and clearing away heat, sore-throat relieving, relieving restlessness, nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, astringing lung QI for relieving asthma, heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds.Monarch, compatibility is proper, is the optimum formula of treatment pediatric wind-heat lung obstruction type pneumonia asthma.Herba Ephedrae: hot, little hardship, temperature.Go into lung, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, diuretic detumescent.Semen Armeniacae Amarum: bitter, hot, temperature, slightly poisonous.Go into lung, large intestine channel.Relieving cough and asthma, loosening bowel to relieve constipation.Gypsum Fibrosum: hot, sweet, Great Cold.Go into lung, stomach warp.Resolving heat and reducing pathogenic fire, relieving restlessness are quenched the thirst, promoting tissue regeneration and ulcer healing.Fructus Viticis: be slightly cold, bitter, hot.Go into bladder, liver, stomach warp.Dispelling wind and heat pathogens, the clear sharp head.Periostracum Cicadae: bitter, cold.Go into lung, Liver Channel.Diffusing wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.Semen Sojae Preparatum: cool, bitter, suffering.Go into lung, stomach warp.Induce sweat, relieving restlessness, a surname sends out hot and suffocating.Folium Mori: bitter, sweet, cold.Go into liver, lung meridian.Expelling wind and clearing away heat, cooling blood for improving eyesight.Flos Chrysanthemi: sweet, be slightly cold.Go into lung, Liver Channel.Diffusing wind heat clearing away, suppressing the hyperactive liver makes eye bright.Radix Asteris: temperature; Hot, sweet, bitter; Return lung meridian.Nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Flos Farfarae: temperature; Hot, little hardship; Return lung meridian.Nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.Semen Ginkgo: flat; Sweet, bitter, puckery; Return lung meridian, poison.Astringing lung QI for relieving asthma, leukorrhagia stopping is turbid, urine reducing.Fructus Perillae: temperature; Hot; Return lung, large intestine channel.The sending down the abnormal ascending QI expectorant is relievingd asthma, intestine moistening.Flos Lonicerae: sweet, cold.Go into lung, the heart, stomach warp.Heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.Fructus Forsythiae: hardship is slightly cold.Go into the heart, small intestine meridian.Heat-clearing and toxic substances removing, the eliminating stagnation of relieving inflammation or internal heat.Folium Isatidis: bitter, salty, Great Cold.Go into the heart, stomach warp.Heat-clearing and toxic substances removing, cooling blood and dissolving purpura.Radix Isatidis: hardship, cold.Go into the heart, stomach warp.Clearing away heat,cooling blood and removing toxin.Herba Patriniae: suffering, hardship is slightly cold.Go into stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, the clots absorbing evacuation of pus.Herba Houttuyniae: suffering is slightly cold.Go into lung, kidney, urinary bladder channel.Separate pyretic toxicity, subduing inflammation, inducing diuresis for treating stranguria syndrome.Fructus Canarii albi: sweet, puckery, sour, flat.Go into lung meridian.Removing heat from the lung and relieving sorethroat, detoxifcation.Radix Sophorae Tonkinensis: cold, bitter.Go into lung, stomach warp.Heat-clearing and toxic substances removing, the detumescence sore-throat relieving.Calyx Seu Fructus Physalis: cold, bitter.Go into lung meridian.Heat-clearing and toxic substances removing, sore-throat relieving reduces phlegm, diuresis.Rhizoma Phragmitis: cold, sweet.Go into lung, lung meridian.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Folium Bambusae: cold, sweet, suffering, light.Go into the heart, stomach, small intestine meridian.Clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Radix Platycodonis: bitter, hot, flat.Go into lung meridian.Lung qi dispersing eliminates the phlegm, removing pus and relieving carbuncle.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Herba Ephedrae 3g, Semen Armeniacae Amarum 3g, Gypsum Fibrosum 3g, Fructus Viticis 6g, Periostracum Cicadae 6g, Semen Sojae Preparatum 6g, Folium Mori 9g, Flos Chrysanthemi 9g, Radix Asteris 6g, Flos Farfarae 6g, Semen Ginkgo 3g, Fructus Perillae 6g, Flos Lonicerae 9g, Fructus Forsythiae 3g, Folium Isatidis 9g, Radix Isatidis 6g, Herba Patriniae 6g, Herba Houttuyniae 6g, Fructus Canarii albi 3g, Radix Sophorae Tonkinensis 3g, Calyx Seu Fructus Physalis 3g, Rhizoma Phragmitis 9g, Folium Bambusae 3g, Radix Platycodonis 6g and Radix Glycyrrhizae 6g, top 25 flavor medicines are put into 1000 ml waters together, soaked 30 minutes, slow fire is fried 30 minutes then, filter and remove residue gets 300 milliliters of medicinal liquids, and fried medicinal liquid is the Chinese medicine of treatment pediatric wind-heat lung obstruction type pneumonia asthma.When the patient of pediatric wind-heat lung obstruction type pneumonia asthma need treat, be 35 ℃ with fluid temperature, each 100 milliliters, every day secondary, three is a course of treatment, if symptom still deposits, obeys for second course of treatment again, so that recovery from illness.
Among the 319 routine pediatric wind-heat lung obstruction type pneumonia asthma patients, male's 183 examples account for 57.3%; Women's 136 examples account for 42.7%.The male is more than the women.
The range of age of table one, 319 routine pediatric wind-heat lung obstruction type pneumonia asthma patients
Age (year) 1~2 3~5 6~10 10~12
The example number 21 130 165 3
Percentage ratio 6.6% 40.8% 51.7% 0.9%
Table two, 319 routine pediatric wind-heat lung obstruction type pneumonia asthma patient curative effect tables
Cure Take a turn for the better Invalid
The example number 317 2 Do not have
Percentage ratio 99.4% 0.6% Do not have
Table three, 319 routine pediatric wind-heat lung obstruction type pneumonia asthma patients show the course of treatment
The treatment natural law 2~3 4~7 8~10 11~21
The example number 12 132 173 2
Percentage ratio 3.8% 41.4% 54.2% 0.6
Information slip before and after table four, the 319 routine pediatric wind-heat lung obstruction type pneumonia asthma patient
Figure GSB00000508865100041

Claims (1)

1. Chinese medicinal preparation method for the treatment of pediatric wind-heat lung obstruction type pneumonia asthma, it is characterized in that: get Herba Ephedrae 3 grams, Semen Armeniacae Amarum 3 grams, Gypsum Fibrosum 3 grams, Fructus Viticis 6 grams, Periostracum Cicadae 6 grams, Semen Sojae Preparatum 6 grams, Folium Mori 9 grams, Flos Chrysanthemi 9 grams, Radix Asteris 6 grams, Flos Farfarae 6 grams, Semen Ginkgo 3 grams, Fructus Perillae 6 grams, Flos Lonicerae 9 grams, Fructus Forsythiae 3 grams, Folium Isatidis 9 grams, Radix Isatidis 6 grams, Herba Patriniae 6 grams, Herba Houttuyniae 6 grams, Fructus Canarii albi 3 grams, Radix Sophorae Tonkinensis 3 grams, Calyx Seu Fructus Physalis 3 grams, Rhizoma Phragmitis 9 grams, Folium Bambusae 3 grams, Radix Platycodonis 6 grams and Radix Glycyrrhizae 6 grams, top 25 flavor medicines are put into 1000 ml waters together, soaked 30 minutes, slow fire is fried 30 minutes then, filter and remove residue gets 300 milliliters of medicinal liquids, and fried medicinal liquid is the Chinese medicine of treatment pediatric wind-heat lung obstruction type pneumonia asthma.
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CN102698165B (en) * 2012-05-04 2014-05-21 李红 Traditional Chinese medicine for treating cough and wind-heat attacked lung pneumonia
CN102743676B (en) * 2012-06-07 2016-03-09 王晓兵 A kind of Chinese medicine fruit and vegerable composite oral liquid of clearing away lung-heat treatment pneumonia
CN102836373B (en) * 2012-09-19 2014-01-22 刘伟 Medicament for treating infantile pneumonia
CN102988713B (en) * 2012-10-29 2015-01-21 相波 TCM (Traditional Chinese medicine) prescription for treating lung-stomach heat-stagnated type pneumonia
CN103041217A (en) * 2013-01-27 2013-04-17 马丽 Traditional Chinese medicine composition for treating pneumonia
CN104800660A (en) * 2015-05-19 2015-07-29 王丽 Traditional Chinese medicine preparation for treating mycoplasma pneumoniae pneumonia and preparation method thereof
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