CN102327392B - Formula of Chinese medicine for treating viral pneumonia - Google Patents
Formula of Chinese medicine for treating viral pneumonia Download PDFInfo
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Abstract
The invention relates to a formula of a Chinese medicine for treating viral pneumonia. The Chinese medicine consists of the following medicinal materials in part by weight: 5 parts of ephedra, 8 parts of bitter apricot seed, 12 parts of palemane prunella, 8 parts of tea leaf, 10 parts of white mulberry root-bark, 10 parts of phellodendron, 12 parts of indigowoad leaf, 6 parts of pueraria flower, 8 parts of liquoric root and 25 parts of gypsum. Clinical tests prove that the Chinese medicine for treating viral pneumonia has the cure rate of 73.3 percent and the total effective rate of 93.3 percent, is safe in administration and almost does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese prescription for the treatment of viral pneumonia.
Background technology
Viral pneumonia be by upper respiratory tract infection, the downward pneumonia due to spreading, be more common in the child.The clinical main manifestations of primary disease is heating, headache, systemic pain, dry cough and lung infiltration etc.Existing medicine mostly is greatly anti-virus formulation, antibiotic or hormones, and is large to the toxic and side effects of human body, and cure rate is lower.
Motherland's Chinese medicine is thought, viral pneumonia genus " heating ", " cough " category.The warm heresy criminal of going up invades the flesh table, defends gas and loses in a surname freely, therefore generate heat, have a headache.Pathogenic heat criminal lung, impairment of purifying function of the lung, body fluid are burnt, therefore cough with ropy sputum.Pathogenic heat is flourishing, then high heat.Disturbed and the cardiopalmus of the mind, deficiency of vital energy sun not gas fills.The then tachypnea of blood stasis supervention, cyanosis.Hyposthenia, if pathogenic heat are caved in, evil Sheng is weakened body resistance, then heart-yang is depleted, causes the crisis of unconsciousness and collapse.
The present Research of the related Chinese crude drug of Chinese prescription that the present invention treats viral pneumonia is as follows:
Herba Ephedrae: [source] is the dry herb stem of Ephedraceae plant plait Herba Ephedrae EphedrasinicaStapf, epheday intermedia EphedraintermediaSchrenketC.A.Mey. or ephedra equisetina EphedraequisetinaBge..[meridian distribution of property and flavor] is hot, little hardship, temperature.Return lung, urinary bladder channel.[function cures mainly] diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Be used for anemofrigid cold, uncomfortable in chest breathing with cough, edema due to wind pathogen edema; Bronchial asthma.Honey Herba Ephedrae nourishing the lung to arrest cough.Multiplex in the table disease separate asthma and cough.[usage and dosage] 2～9g.
Semen Armeniacae Amarum: [source] is the dry mature seed of rosaceous plant Prunus armeniaca L.var.ansu Maxim. PrunusarmeniacaL.var.ansuMaxim., Siberia Fructus Pruni PrunussibiricaL., prunus mandshuricaKoehne Prunusmandshurica (Maxim.) Koehne or Fructus Pruni PrunusarmeniacaL..[meridian distribution of property and flavor] hardship, tepor; Slightly poisonous.Return lung, large intestine channel.[function cures mainly] sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation.Be used for cough and asthma, the fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, the dryness of the intestine constipation.[usage and dosage] 4.5～9g.[attention] is for oral administration unsuitable excessive, in order to avoid poison.
Herba Ajugae: [source] is the herb of labiate ajuga decumbens.Latin plant animal mineral name: Ajuga decumbens Thunb.[meridian distribution of property and flavor] bitter in the mouth; Sweet; Cold in nature.Return lung; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Preventing phlegm from forming and stopping coughing; Removing pathogenic heat from blood and dissipating blood stasis.Main laryngopharynx swelling and pain; The cough due to lung-heat; Lung abscess; Conjunctival congestion and swelling pain; Dysentery; The carbuncle furuncle; Venom; Traumatic injury.[usage and dosage] is for oral administration, 10-30g.
Folium Camelliae sinensis: be processed into for tender leaf or the tender shoots of plant of theaceae tea in [source], Latin plant animal mineral name Camellia sinensis (L.) O.Kuntze ［ Thea sinensis L. ］ [meridian distribution of property and flavor] hardship; Sweet; Cool.GUIXIN; Lung; Stomach; Liver; Spleen; Kidney channel.[function cures mainly] refresh oneself; Relieving thirst and restlessness; Help digestion; Reduce phlegm; Diuresis; Detoxifcation.[usage and dosage] 3-10g.
Cortex Mori: [source] is the dry root bark of moraceae plants Mulberry Morus alba L..[meridian distribution of property and flavor] is sweet, and be cold.Return lung meridian.[function cures mainly] eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.Be used for dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.[usage and dosage] 6～12g.
Cortex Phellodendri: [source] is the dry bark of rutaceae wampee PhellodendronchinenseSchneid..[meridian distribution of property and flavor] hardship, cold.Return kidney, urinary bladder channel.[function cures mainly] heat clearing and damp drying, pathogenic fire purging is except steaming, and skin ulcer is treated in detoxifcation.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.[usage and dosage] 3～12g
Folium Isatidis: [source] is the dried leaves of cruciferae isatis Isatis indigotica Fort..Meridian distribution of property and flavor: cold; Bitter; GUIXIN, stomach warp.[meridian distribution of property and flavor] hardship, cold.GUIXIN, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be used for the high heat of epidemic febrile disease, coma is sent out the speckle dermexanthesis, mumps, sore throat, erysipelas, carbuncle.[usage and dosage] 9～15g.
Flos puerariae lobatae: [source] is the flower of legume pueraria lobata Pueraria lobata (Willd.) Ohwi, bitter Pueraria lobata Pueraria thomsonii Benth..[meridian distribution of property and flavor] sweet in the mouth; Cool in nature.Return the stomach warp.[function cures mainly] relieving acute alcoholism and recuperating the spleen, hemostasis, lung heat clearing.Cure mainly: the dysphoria with smothery sensation of getting sick from drinking too much wine is thirsty; Headache and dizzy; Distension and fullness in the abdomen; The vomiting acid regurgitation; Anorexia; Spit blood; Discharging fresh blood stool.[usage and dosage] 3-9g.
Radix Glycyrrhizae: [source] is the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[meridian distribution of property and flavor] is sweet, and be flat.GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.[usage and dosage] 1.5～9g.
Gypsum Fibrosum: [source] is Sulfates mineral anhydrite family Gypsum Fibrosum, the main hydrous calcium sulfate (CaSO that contains
42H
2O), after excavating, remove silt and assorted stone.[nature and flavor with return through] are sweet, hot, Great Cold.Attach to the lung and stomach meridians.[function with cure mainly] clearing away heat-fire, relieving restlessness is quenched the thirst.Be used for fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.[usage and consumption] 15～60g.
Summary of the invention
The present invention aims to provide a kind of Chinese prescription for the treatment of viral pneumonia, by selecting suitable compound ratio, reaches strengthening the body resistance, heat-clearing and toxic substances removing, thus the purpose of Cure Viruses pneumonia.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese prescription for the treatment of viral pneumonia, medical material by following weight proportion forms: Herba Ephedrae 2-9 part, Semen Armeniacae Amarum 4.5-9 part, Herba Ajugae 10-30 part, Folium Camelliae sinensis 3-10 part, Cortex Mori 6-12 part, Cortex Phellodendri 3-12 part, Folium Isatidis 9-15 part, Flos puerariae lobatae 3-9 part, Radix Glycyrrhizae 1.5-9 part, Gypsum Fibrosum 15-60 part.
The optimum weight proportioning of its Chinese crude drug is: 5 parts in Herba Ephedrae, 8 parts of Semen Armeniacae Amarums, 12 parts of Herba Ajugaes, 8 parts of Folium Camelliae sinensis, 10 parts of Cortex Mori, 10 parts of Cortex Phellodendris, 12 parts of Folium Isatidiss, 6 parts of Flos puerariae lobataes, 8 parts in Radix Glycyrrhizae, 25 parts in Gypsum Fibrosum.
Use optimum weight proportioning of the present invention to make the preparation method of capsule:
Take by weighing Herba Ephedrae 5 grams, Semen Armeniacae Amarum 8 grams, Herba Ajugae 12 grams, Folium Camelliae sinensis 8 grams, Cortex Mori 10 grams, Cortex Phellodendri 10 grams, Folium Isatidis 12 grams, Flos puerariae lobatae 6 grams, Radix Glycyrrhizae 8 grams, Gypsum Fibrosum 25 grams; Add 8 times of water gagings, decocted 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying incapsulates shell, namely gets the capsule that meets one day consumption of normal adult.Take for general minute 2-3 time.
The good effect that we are bright:
Tcm theory thinks, viral pneumonia is that exopathogen is invaded body, contains heat in the lung, and therefore the QI rising in reverse order impairment of body fluid is the fever of the body cough with asthma.This moment is anxious when clear eliminating the pathogens from the lung heat, makes hot clearing heat in QI system flat and breath with cough to such an extent that end.The side is monarch with Herba Ephedrae, gets its energy lung qi dispersing and the heresy that expels the heat-evil, and it is warm in nature, the Gypsum Fibrosum that is equipped with hot sweet Great Cold is ministerial drug, lung qi dispersing and do not help heat, lung heat clearing and do not stay heresy, lung qi falls in Semen Armeniacae Amarum, Folium Camelliae sinensis, Cortex Mori help clearing away lung-heat, Herba Imperatae Spica Prunellae, Cortex Phellodendri, Folium Isatidis detoxicating, relieving inflammation, the sharp stomach of Flos puerariae lobatae lung heat clearing, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, respectful the falling of lung qi had the right, and dyspnea with rapid respiration can be put down.
The clinical trial confirmation, the present invention reaches 73.3% to the cure rate of viral pneumonia, and total effective rate reaches 93.3%, and drug safety, does not almost have toxic and side effects.Below in conjunction with clinical testing data beneficial effect of the present invention is described:
From year February in February, 2008 to 2011, the inventor uses capsule treatment viral pneumonia patient 75 examples that optimum weight proportioning prescription of the present invention makes in Yantai City's Fushan District the People's Hospital, and with use amantadine treatment viral pneumonia 30 examples the same period and carry out controlled observation.
1, clinical data
Physical data is observed case totally 105 examples, is divided at random 2 groups.Treatment group 75 examples, male 30 examples, women 45 examples; Year at age (39.5 ± 25.27); The course of disease (2 ± 1) sky; Matched group 30 examples, male 20 examples, women 10 examples; Year at age (39.5 ± 26.27); The course of disease (2 ± 1) sky.2 groups of physical data are learned processing by statistics, and there are no significant that meaning (P＞0.05) has comparability for difference.
2, Therapeutic Method
2.1 matched group adopts amantadine, 0.1g, 2 times/d, the 3-5 days course for the treatment of.
2.2 the capsule that treatment group adopts oral optimum weight proportioning prescription of the present invention to make, every day 2 times, the 3-5 days course for the treatment of.
2.3 observation item: clinical efficacy: following all situation changes before and after comprising treatment: the upper airway symptoms such as dry pharynx, pharyngalgia, sneeze, watery nasal discharge, heating, headache, poor appetite and systemic pain, and pathological changes is involved pulmonary parenchyma can cough, chest pain, the symptom such as breathe hard; The x-ray rabat, blood test, etiological examination, the auxiliary examination indexs such as Serological testing.
2.4 statistical method adopts the SPSS statistical software to analyze.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".
Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal; Take a turn for the better: clinical symptom relief, lab testing improve or are normal; Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 therapeutic outcome
Two groups of Clinical efficacy comparisons see Table 1.
Table 1 liang group Clinical efficacy comparison
| Group | n | Recovery from illness | Take a turn for the better | Invalid | The untoward reaction example | Total effective rate (%) |
| Treatment group | 75 | 55(73.3%) | 15(20%) | 5(6.7%) | 0 | 93.3% |
| Matched group | 30 | 12(40%) | 11(36.6%) | 7(23.4%) | 3（10%） | 76.6% |
Experimental observation, total effective rate treatment group are 93.3%, and matched group is 76.6%, 2 group of comparison, and difference has significant (P＜0.05).As seen, the medicine that optimum weight proportioning prescription of the present invention makes is respond well for the treatment viral pneumonia, and does not almost have untoward reaction to occur, and takes safe.
According to above-mentioned clinical experiment data, treat Chinese medicine Analysis on Mechanism and the general knowledge known in this field of viral pneumonia in conjunction with the present invention, those skilled in the art easily know by inference, use the medical material among the present invention, in the conventional amount used scope, be Herba Ephedrae 2-9 part, Semen Armeniacae Amarum 4.5-9 part, Herba Ajugae 10-30 part, Folium Camelliae sinensis 3-10 part, Cortex Mori 6-12 part, Cortex Phellodendri 3-12 part, Folium Isatidis 9-15 part, Flos puerariae lobatae 3-9 part, Radix Glycyrrhizae 1.5-9 part, Gypsum Fibrosum 15-60 part can be obtained the similar technique effect of medicine that makes with optimum weight proportioning prescription of the present invention.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing Herba Ephedrae 5 grams, Semen Armeniacae Amarum 8 grams, Herba Ajugae 12 grams, Folium Camelliae sinensis 8 grams, Cortex Mori 10 grams, Cortex Phellodendri 10 grams, Folium Isatidis 12 grams, Flos puerariae lobatae 6 grams, Radix Glycyrrhizae 8 grams, Gypsum Fibrosum 25 grams; Add 8 times of water gagings, decocted 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying incapsulates shell, namely gets the capsule that meets one day consumption of normal adult.
Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Generally acknowledge minimum onset consumption according to each medical material of the present invention, take by weighing Herba Ephedrae 2 grams, Semen Armeniacae Amarum 4.5 grams, Herba Ajugae 10 grams, Folium Camelliae sinensis 3 grams, Cortex Mori 6 grams, Cortex Phellodendri 3 grams, Folium Isatidis 9 grams, Flos puerariae lobatae 3 grams, Radix Glycyrrhizae 1.5 grams, Gypsum Fibrosum 15 grams; Add 10 times of water gagings, decocted 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, drying, packing namely gets the powder that meets one day consumption of normal adult.
Oral, take once every day.
Specific embodiment 3
According to the high safety using amount of each medical material acknowledged of the present invention, take by weighing Herba Ephedrae 9 grams, Semen Armeniacae Amarum 9 grams, Herba Ajugae 30 grams, Folium Camelliae sinensis 10 grams, Cortex Mori 12 grams, Cortex Phellodendri 12 grams, Folium Isatidis 15 grams, Flos puerariae lobatae 9 grams, Radix Glycyrrhizae 9 grams, Gypsum Fibrosum 60 grams; Add 6 times of water gagings, decocted 1 hour, filter, filtrate is concentrated, adds an amount of dextrin and correctives, granulates according to this area common process, and packing can make the granule that meets one day consumption of normal adult.
Oral, every bu morning, noon and afternoon take for three times.
Claims (2)
1. Chinese medicine composition for the treatment of viral pneumonia, it is characterized in that, it is comprised of the medical material of following weight proportion: Herba Ephedrae 2-9 part, Semen Armeniacae Amarum 4.5-9 part, Herba Ajugae 10-30 part, Folium Camelliae sinensis 3-10 part, Cortex Mori 6-12 part, Cortex Phellodendri 3-12 part, Folium Isatidis 9-15 part, Flos puerariae lobatae 3-9 part, Radix Glycyrrhizae 1.5-9 part, Gypsum Fibrosum 15-60 part.
2. according to the Chinese medicine composition for the treatment of viral pneumonia claimed in claim 1, it is characterized in that, it is comprised of the medical material of following weight proportion: 5 parts in Herba Ephedrae, 8 parts of Semen Armeniacae Amarums, 12 parts of Herba Ajugaes, 8 parts of Folium Camelliae sinensis, 10 parts of Cortex Mori, 10 parts of Cortex Phellodendris, 12 parts of Folium Isatidiss, 6 parts of Flos puerariae lobataes, 8 parts in Radix Glycyrrhizae, 25 parts in Gypsum Fibrosum.
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| CN1337252A (en) * | 2001-07-17 | 2002-02-27 | 陈华琴 | Chinese medicine for treating chronic bronchitis |
| CN100443108C (en) * | 2004-03-29 | 2008-12-17 | 张兆春 | Plaster for treating pneumonia and tracheitis and its preparing method |
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| CN1337252A (en) * | 2001-07-17 | 2002-02-27 | 陈华琴 | Chinese medicine for treating chronic bronchitis |
| CN100443108C (en) * | 2004-03-29 | 2008-12-17 | 张兆春 | Plaster for treating pneumonia and tracheitis and its preparing method |
| CN101480437A (en) * | 2008-01-11 | 2009-07-15 | 曾雄辉 | Method for preparing decoction containing ephedra, apricot kernel, gypsum, and licorice |
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