CN102099378B - 针对CXCR4和其他GPCRs的氨基酸序列以及包含所述氨基酸序列的多肽 - Google Patents

针对CXCR4和其他GPCRs的氨基酸序列以及包含所述氨基酸序列的多肽 Download PDF

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CN102099378B
CN102099378B CN200980127612.4A CN200980127612A CN102099378B CN 102099378 B CN102099378 B CN 102099378B CN 200980127612 A CN200980127612 A CN 200980127612A CN 102099378 B CN102099378 B CN 102099378B
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acid sequence
sequences
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CN102099378A (zh
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克里斯托夫·布朗什托
马丁·斯密特
雷格留斯·勒尔
斯文·耶尼兴
迈克尔·约翰·斯科特·桑德斯
约翰内斯·约瑟夫·威廉姆斯·德哈德
彼得·万兰德舒特
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
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    • A—HUMAN NECESSITIES
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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CN200980127612.4A 2008-05-16 2009-05-18 针对CXCR4和其他GPCRs的氨基酸序列以及包含所述氨基酸序列的多肽 Active CN102099378B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5384708P 2008-05-16 2008-05-16
US61/053,847 2008-05-16
US10214208P 2008-10-02 2008-10-02
US61/102,142 2008-10-02
PCT/EP2009/056026 WO2009138519A1 (en) 2008-05-16 2009-05-18 AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME

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CN102099378A CN102099378A (zh) 2011-06-15
CN102099378B true CN102099378B (zh) 2016-01-20

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US (1) US9212226B2 (https=)
EP (1) EP2285833B1 (https=)
JP (1) JP6034023B2 (https=)
KR (1) KR20110020825A (https=)
CN (1) CN102099378B (https=)
AU (1) AU2009248049B2 (https=)
BR (1) BRPI0911984A2 (https=)
CA (1) CA2724208C (https=)
IL (1) IL209176A0 (https=)
MX (1) MX2010012518A (https=)
NZ (1) NZ589036A (https=)
RU (1) RU2010151725A (https=)
WO (1) WO2009138519A1 (https=)
ZA (1) ZA201008180B (https=)

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EP2285833A1 (en) 2011-02-23
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US20110206660A1 (en) 2011-08-25
AU2009248049B2 (en) 2015-07-23
IL209176A0 (en) 2011-01-31
RU2010151725A (ru) 2012-06-27
CN102099378A (zh) 2011-06-15
US9212226B2 (en) 2015-12-15
MX2010012518A (es) 2010-12-06
JP6034023B2 (ja) 2016-11-30
BRPI0911984A2 (pt) 2016-09-20
JP2011523550A (ja) 2011-08-18
ZA201008180B (en) 2011-09-28
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