CN102065694A - 用于局部治疗免疫相关疾病的雾化的lfa-1拮抗剂 - Google Patents
用于局部治疗免疫相关疾病的雾化的lfa-1拮抗剂 Download PDFInfo
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- CN102065694A CN102065694A CN2009801216848A CN200980121684A CN102065694A CN 102065694 A CN102065694 A CN 102065694A CN 2009801216848 A CN2009801216848 A CN 2009801216848A CN 200980121684 A CN200980121684 A CN 200980121684A CN 102065694 A CN102065694 A CN 102065694A
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- lfa
- antagonist
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- aliphatic
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- 0 CC(C(C(*)CC(C1)C2CCN1C(C1CC(*CC3)C3CC1)O)C2Cl)NC(C1)(C1C(CCC1)CC1[Sn](C)CO)C(O)=O Chemical compound CC(C(C(*)CC(C1)C2CCN1C(C1CC(*CC3)C3CC1)O)C2Cl)NC(C1)(C1C(CCC1)CC1[Sn](C)CO)C(O)=O 0.000 description 2
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4525708P | 2008-04-15 | 2008-04-15 | |
| US61/045,257 | 2008-04-15 | ||
| PCT/US2009/002388 WO2009128933A1 (en) | 2008-04-15 | 2009-04-15 | Aerosolized lfa-1 antagonists for use in localized treatment of immune related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102065694A true CN102065694A (zh) | 2011-05-18 |
Family
ID=41164173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009801216848A Pending CN102065694A (zh) | 2008-04-15 | 2009-04-15 | 用于局部治疗免疫相关疾病的雾化的lfa-1拮抗剂 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20090257957A1 (enExample) |
| EP (1) | EP2265124A4 (enExample) |
| JP (4) | JP2011518155A (enExample) |
| CN (1) | CN102065694A (enExample) |
| WO (1) | WO2009128933A1 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920138A (zh) * | 2014-04-17 | 2014-07-16 | 兆科药业(广州)有限公司 | 一种药物组合物及其制剂与应用 |
| CN106995439A (zh) * | 2016-01-26 | 2017-08-01 | 镇江圣安医药有限公司 | 氘取代3‑(甲磺酰基)‑l‑苯丙氨酸衍生物及其药物组合物、药物制剂和用途 |
| CN109906081A (zh) * | 2016-09-01 | 2019-06-18 | 加莱拉实验室有限责任公司 | 利用五氮杂大环络合物和抗坏血酸类化合物的联合癌症疗法 |
| CN111588730A (zh) * | 2020-06-10 | 2020-08-28 | 中山大学中山眼科中心 | FL2-siRNA在制备治疗角膜碱烧伤药物中的应用及角膜碱烧伤药物 |
| CN114025759A (zh) * | 2019-04-18 | 2022-02-08 | 阿祖拉眼科有限公司 | 用于治疗眼病的化合物和方法 |
| CN116635032A (zh) * | 2020-10-21 | 2023-08-22 | 阿祖拉眼科有限公司 | 用于治疗眼部病症的化合物和方法 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8926990B2 (en) | 2009-10-13 | 2015-01-06 | Rutgers, The State University Of New Jersey | Treatment and diagnosis of inflammatory disorders and HIV |
| WO2009128934A1 (en) * | 2008-04-15 | 2009-10-22 | Sarcode Corporation | Topical lfa-1 antagonists for use in localized treatment of immune related disorders |
| CN102065893A (zh) * | 2008-04-15 | 2011-05-18 | 萨可德公司 | Lfa-1拮抗剂向胃肠系统的递送 |
| US8623330B2 (en) * | 2010-03-18 | 2014-01-07 | Precision Dermatology, Inc. | Emollient foams for treatment of seborrheic dermatitis |
| US8592380B2 (en) * | 2010-03-26 | 2013-11-26 | Precision Dermatology, Inc. | Aerosol foams comprising clindamycin phosphate |
| CA2802041A1 (en) | 2010-06-11 | 2011-12-15 | Precision Dermatology, Inc. | High oil-content emollient aerosol foam compositions |
| CN103917265B (zh) * | 2011-03-03 | 2017-02-15 | 英倍尔药业股份有限公司 | 鼻药递送装置 |
| CN104955453B (zh) | 2012-12-19 | 2018-09-18 | 原生质生物科学股份有限公司 | Lfa-1抑制剂制剂 |
| US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| CA2910766C (en) | 2013-04-30 | 2020-12-15 | Otitopic Inc. | Dry powder formulations and methods of use |
| EP3105146B1 (en) | 2014-02-14 | 2019-10-16 | Mission Pharmacal Company | Spray delivery device |
| AU2015217274B2 (en) | 2014-02-14 | 2019-07-25 | Mission Pharmacal Company | Sprayable composition containing zinc oxide and a fluoro-olefin propellant |
| WO2015123238A1 (en) * | 2014-02-14 | 2015-08-20 | Mission Pharmacal Company | Stabilized, sprayable emulsion containing active agent particles |
| JP6649376B2 (ja) * | 2014-06-20 | 2020-02-19 | ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー | 肺の炎症を治療する方法 |
| WO2019059953A2 (en) | 2017-09-22 | 2019-03-28 | Otitopic Inc. | DRY POWDER COMPOSITIONS CONTAINING MAGNESIUM STEARATE |
| US10786456B2 (en) | 2017-09-22 | 2020-09-29 | Otitopic Inc. | Inhaled aspirin and magnesium to treat inflammation |
| EP4589369A1 (en) * | 2022-09-15 | 2025-07-23 | NOF Corporation | Solution for contact lenses |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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-
2009
- 2009-04-15 US US12/386,363 patent/US20090257957A1/en not_active Abandoned
- 2009-04-15 EP EP09733386A patent/EP2265124A4/en not_active Ceased
- 2009-04-15 JP JP2011505027A patent/JP2011518155A/ja not_active Withdrawn
- 2009-04-15 CN CN2009801216848A patent/CN102065694A/zh active Pending
- 2009-04-15 WO PCT/US2009/002388 patent/WO2009128933A1/en not_active Ceased
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2013
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2014
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-
2016
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-
2017
- 2017-05-30 JP JP2017106334A patent/JP2017141310A/ja active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920138A (zh) * | 2014-04-17 | 2014-07-16 | 兆科药业(广州)有限公司 | 一种药物组合物及其制剂与应用 |
| CN106995439A (zh) * | 2016-01-26 | 2017-08-01 | 镇江圣安医药有限公司 | 氘取代3‑(甲磺酰基)‑l‑苯丙氨酸衍生物及其药物组合物、药物制剂和用途 |
| CN106995439B (zh) * | 2016-01-26 | 2019-09-20 | 镇江圣安医药有限公司 | 氘取代3-(甲磺酰基)-l-苯丙氨酸衍生物及其药物组合物、药物制剂和用途 |
| CN109906081A (zh) * | 2016-09-01 | 2019-06-18 | 加莱拉实验室有限责任公司 | 利用五氮杂大环络合物和抗坏血酸类化合物的联合癌症疗法 |
| CN114025759A (zh) * | 2019-04-18 | 2022-02-08 | 阿祖拉眼科有限公司 | 用于治疗眼病的化合物和方法 |
| CN111588730A (zh) * | 2020-06-10 | 2020-08-28 | 中山大学中山眼科中心 | FL2-siRNA在制备治疗角膜碱烧伤药物中的应用及角膜碱烧伤药物 |
| CN116635032A (zh) * | 2020-10-21 | 2023-08-22 | 阿祖拉眼科有限公司 | 用于治疗眼部病症的化合物和方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090257957A1 (en) | 2009-10-15 |
| EP2265124A1 (en) | 2010-12-29 |
| EP2265124A4 (en) | 2011-12-28 |
| JP2016128515A (ja) | 2016-07-14 |
| JP2017141310A (ja) | 2017-08-17 |
| WO2009128933A1 (en) | 2009-10-22 |
| JP2014132033A (ja) | 2014-07-17 |
| US20140079784A1 (en) | 2014-03-20 |
| JP2011518155A (ja) | 2011-06-23 |
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