CN102046806B - 微阵列系统 - Google Patents

微阵列系统 Download PDF

Info

Publication number
CN102046806B
CN102046806B CN200880129099.8A CN200880129099A CN102046806B CN 102046806 B CN102046806 B CN 102046806B CN 200880129099 A CN200880129099 A CN 200880129099A CN 102046806 B CN102046806 B CN 102046806B
Authority
CN
China
Prior art keywords
microarray
hydrophilic
chamber
systems
incubation chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200880129099.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN102046806A (zh
Inventor
克里斯托弗·G·库尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akonni Biosystems Inc
Original Assignee
Akonni Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akonni Biosystems Inc filed Critical Akonni Biosystems Inc
Publication of CN102046806A publication Critical patent/CN102046806A/zh
Application granted granted Critical
Publication of CN102046806B publication Critical patent/CN102046806B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00387—Applications using probes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00529—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/049—Valves integrated in closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0605—Valves, specific forms thereof check valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN200880129099.8A 2008-05-09 2008-05-09 微阵列系统 Active CN102046806B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/005933 WO2009136892A1 (en) 2008-05-09 2008-05-09 Microarray system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201410430953.1A Division CN104263631A (zh) 2008-05-09 2008-05-09 微阵列系统

Publications (2)

Publication Number Publication Date
CN102046806A CN102046806A (zh) 2011-05-04
CN102046806B true CN102046806B (zh) 2014-10-08

Family

ID=41264805

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880129099.8A Active CN102046806B (zh) 2008-05-09 2008-05-09 微阵列系统

Country Status (5)

Country Link
EP (2) EP2703500B1 (enExample)
JP (1) JP5490783B2 (enExample)
CN (1) CN102046806B (enExample)
CA (1) CA2723707C (enExample)
WO (1) WO2009136892A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030643A1 (it) 2003-04-01 2004-10-02 Copan Innovation Ltd Tampone per il prelievo di campioni biologici
US10125388B2 (en) 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
WO2011011062A2 (en) * 2009-07-24 2011-01-27 Akonni Biosystems Flow cell device
EP2263549B1 (en) 2010-04-21 2013-06-26 Puritan Medical Products Company, LLC Collection device and material
IT1401447B1 (it) 2010-06-09 2013-07-26 Copan Italia Spa Metodo per il trasferimento quantitativo di analiti
CA2858608C (en) 2010-12-09 2020-03-10 Akonni Biosystems Sample analysis system
IT1403618B1 (it) * 2011-01-05 2013-10-31 Copan Italia Spa Procedimento per realizzare un dispositivo per il prelievo ed il trasferimento di campioni per biologia molecolare
CN102206573B (zh) * 2011-03-22 2014-12-31 博奥生物有限公司 用于微阵列芯片的自动进样装置及自动进样杂交微阵列芯片
CN102199529A (zh) * 2011-03-22 2011-09-28 博奥生物有限公司 一种生物芯片杂交系统
CN105289762B (zh) 2011-04-13 2017-07-18 阿科尼生物系统公司 基于微阵列的样检系统
KR101275742B1 (ko) * 2011-06-23 2013-06-17 주식회사 아이센스 광학 분석용 셀
ITTO20110854A1 (it) * 2011-09-23 2013-03-24 St Microelectronics Srl Dispositivo e metodo per misurare la concentrazione di materiali biologici, in particolare l'ormone di stimolazione della tiroide, in un campione
JP5825190B2 (ja) * 2012-04-26 2015-12-02 コニカミノルタ株式会社 アナライトを検出または定量するためのラテラルフロー型クロマト法用テストストリップ
ITMI20121603A1 (it) 2012-09-25 2014-03-26 Copan Italia Spa Dispositivo e metodo per il prelievo ed il trasferimento di campioni di materiale biologico
EP3919174A3 (en) * 2012-10-24 2022-03-09 Genmark Diagnostics Inc. Integrated multiplex target analysis
WO2014069063A1 (ja) * 2012-10-29 2014-05-08 京セラ株式会社 弾性表面波センサ
SG10201808874XA (en) * 2014-04-09 2018-11-29 Agency Science Tech & Res Microfluidic device
US11333674B2 (en) 2015-11-16 2022-05-17 Otsuka Pharmaceutical Co., Ltd. Test kit, liquid delivery method and testing apparatus using test kit
CN110501491B (zh) * 2019-09-20 2022-07-26 四川微康朴澜医疗科技有限责任公司 可支持芯片倾斜的多通道孵育装置及试样制备设备
CN110501514B (zh) * 2019-09-20 2023-12-22 四川朴澜医疗科技有限公司 自动检测仪及自动检测系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003015922A1 (en) * 2001-08-20 2003-02-27 Biomicro Systems, Inc. Laminated microarray interface device
EP1374988A2 (en) * 2002-06-21 2004-01-02 Agilent Technologies, Inc. Array assay devices and methods of using the same
EP1374996A1 (en) * 2002-06-21 2004-01-02 Agilent Technologies, Inc. Array assay devices and methods of using the same

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
EP1136556B1 (en) 1991-11-25 2005-06-08 Enzon, Inc. Method of producing multivalent antigen-binding proteins
RU2041262C1 (ru) 1993-08-11 1995-08-09 Институт молекулярной биологии им.В.А.Энгельгардта РАН Способ иммобилизации водорастворимых биоорганических соединений на капиллярно-пористый носитель
RU2041261C1 (ru) 1993-08-11 1995-08-09 Институт молекулярной биологии им.В.А.Энгельгардта РАН Способ изготовления матрицы для детектирования мисматчей
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
EP1959255A3 (en) * 1997-04-04 2008-09-24 Caliper Life Sciences, Inc. Closed-loop biochemical analyzers
US5981734A (en) 1997-07-17 1999-11-09 University Of Chicago Methods for immobilizing nucleic acids on a gel substrate
JP3302003B2 (ja) 2000-03-08 2002-07-15 三洋電機株式会社 オートフォーカス機能を有する撮像装置
JP3629405B2 (ja) * 2000-05-16 2005-03-16 コニカミノルタホールディングス株式会社 マイクロポンプ
CA2450676C (en) * 2001-03-09 2010-03-30 Biomicro Systems, Inc. Method and system for microfluidic interfacing to arrays
JP4566456B2 (ja) * 2001-05-31 2010-10-20 独立行政法人理化学研究所 微量液体制御機構および微量液体制御方法
US7201833B2 (en) * 2001-06-04 2007-04-10 Epocal Inc. Integrated solid-phase hydrophilic matrix circuits and micro-arrays
WO2003006964A1 (en) * 2001-07-12 2003-01-23 Aclara Biosciences, Inc. Submersible light-directing member for material excitation in microfluidic devices
US6656725B2 (en) 2001-08-15 2003-12-02 The University Of Chicago Method of fabrication of microarray of gel-immobilized compounds on a chip by copolymerization
JP2003190751A (ja) * 2001-12-25 2003-07-08 Minolta Co Ltd 混合方法、混合装置、及び該混合装置を用いた検査装置
JP2003232791A (ja) * 2002-02-12 2003-08-22 Olympus Optical Co Ltd プローブ固相化反応アレイ
JP4083452B2 (ja) * 2002-03-28 2008-04-30 旭化成株式会社 バルブ機構
CA2482887A1 (en) * 2002-04-19 2003-10-30 Pamgene B.V. System, substrate plate and incubation device for conducting bioassays
JP3610349B2 (ja) * 2002-08-06 2005-01-12 キヤノン株式会社 液体搬送装置
JP2005037368A (ja) * 2003-05-12 2005-02-10 Yokogawa Electric Corp 化学反応用カートリッジおよびその作製方法および化学反応用カートリッジ駆動システム
JP2005098790A (ja) * 2003-09-24 2005-04-14 Cstec Kk 検査用チップ
JP3860174B2 (ja) * 2004-03-01 2006-12-20 倉敷紡績株式会社 同時多検体ハイブリダイゼーション方法
AU2005272546B2 (en) * 2004-08-12 2010-11-11 Yuji Kikuchi Micro channel array
JP4470640B2 (ja) * 2004-08-12 2010-06-02 東ソー株式会社 微粒子製造方法及びそのための微小流路構造体
JP4403954B2 (ja) * 2004-11-24 2010-01-27 パナソニック株式会社 攪拌装置とこれを用いた攪拌方法
JP4422702B2 (ja) * 2005-07-01 2010-02-24 株式会社神鋼環境ソリューション 蓄熱装置への蓄熱方法
DE602005013948D1 (de) * 2005-07-12 2009-05-28 Sartorius Stedim Biotech Gmbh Microarray-Vorrichtung mit mikroporöser Membrane und einer Inkubationskammernanordnung
JP2007083191A (ja) * 2005-09-22 2007-04-05 Konica Minolta Medical & Graphic Inc マイクロリアクタ
JP2007121278A (ja) * 2005-09-30 2007-05-17 Toray Ind Inc 分析チップおよび分析方法
WO2007055151A1 (ja) * 2005-11-11 2007-05-18 Konica Minolta Medical & Graphic, Inc. マイクロリアクタおよびマイクロ分析システム
JP2007171144A (ja) * 2005-12-26 2007-07-05 Toray Ind Inc カバーを有するマイクロアレイ
US20070202560A1 (en) * 2006-02-24 2007-08-30 National Food Research Institute Resin microchannel array, method of manufacturing the same and blood test method using the same
JP4682874B2 (ja) * 2006-03-01 2011-05-11 コニカミノルタエムジー株式会社 マイクロリアクタ
JP4775039B2 (ja) * 2006-03-03 2011-09-21 パナソニック株式会社 マイクロ流体チップ
US20080124716A1 (en) * 2006-11-29 2008-05-29 Northrop Grumman Systems Corporation Method and device for time-effective biomolecule detection
US20100101660A1 (en) * 2007-02-27 2010-04-29 Konica Minolta Holdings, Inc. Channel switching system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003015922A1 (en) * 2001-08-20 2003-02-27 Biomicro Systems, Inc. Laminated microarray interface device
EP1374988A2 (en) * 2002-06-21 2004-01-02 Agilent Technologies, Inc. Array assay devices and methods of using the same
EP1374996A1 (en) * 2002-06-21 2004-01-02 Agilent Technologies, Inc. Array assay devices and methods of using the same

Also Published As

Publication number Publication date
WO2009136892A1 (en) 2009-11-12
EP2281057B1 (en) 2013-12-25
EP2281057A1 (en) 2011-02-09
EP2281057A4 (en) 2011-10-19
JP2011523698A (ja) 2011-08-18
EP2703500B1 (en) 2020-01-08
CA2723707C (en) 2016-08-23
JP5490783B2 (ja) 2014-05-14
CA2723707A1 (en) 2009-11-12
EP2703500A2 (en) 2014-03-05
HK1157412A1 (en) 2012-06-29
CN102046806A (zh) 2011-05-04
EP2703500A3 (en) 2014-07-02

Similar Documents

Publication Publication Date Title
CN102046806B (zh) 微阵列系统
US8680025B2 (en) Microarray system
CN102667477B (zh) 流通池装置
CN104254395B (zh) 用于分析物测定的序贯侧向流动毛细管装置
DK1843850T3 (en) LATERAL FLOW STEERING CAPILLAR DEVICE
CN105050720A (zh) 顺序递送流体体积和相关的设备、系统和方法
JP2022522866A (ja) アッセイデバイスにおける試薬の配備
CN104263631A (zh) 微阵列系统
HK1157412B (en) Microarray system
HK1231117A1 (en) Flow cell device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1157412

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1157412

Country of ref document: HK

EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20110504

Assignee: Shanghai Ruian Gene Technology Co., Ltd.

Assignor: Akonni Biosystems

Contract record no.: 2019990000134

Denomination of invention: Molecule making for identifying liver fibrosis and hepatic cirrhosis and micro-array system plate thereof

Granted publication date: 20141008

License type: Exclusive License

Record date: 20190429

EE01 Entry into force of recordation of patent licensing contract