CN102037969A - Sterilization composition containing imibenconazole and methoxyl acrylate compound - Google Patents
Sterilization composition containing imibenconazole and methoxyl acrylate compound Download PDFInfo
- Publication number
- CN102037969A CN102037969A CN201110006168XA CN201110006168A CN102037969A CN 102037969 A CN102037969 A CN 102037969A CN 201110006168X A CN201110006168X A CN 201110006168XA CN 201110006168 A CN201110006168 A CN 201110006168A CN 102037969 A CN102037969 A CN 102037969A
- Authority
- CN
- China
- Prior art keywords
- glyoxalin
- kresoxim
- active component
- enestroburin
- pyraclostrobin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 59
- -1 methoxyl acrylate compound Chemical class 0.000 title claims abstract description 44
- AGKSTYPVMZODRV-UHFFFAOYSA-N imibenconazole Chemical compound C1=CC(Cl)=CC=C1CSC(CN1N=CN=C1)=NC1=CC=C(Cl)C=C1Cl AGKSTYPVMZODRV-UHFFFAOYSA-N 0.000 title abstract description 4
- 230000001954 sterilising effect Effects 0.000 title abstract 3
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 3
- 239000005869 Pyraclostrobin Substances 0.000 claims abstract description 45
- VMNULHCTRPXWFJ-UJSVPXBISA-N enoxastrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)\C=C\C1=CC=C(Cl)C=C1 VMNULHCTRPXWFJ-UJSVPXBISA-N 0.000 claims abstract description 45
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 claims abstract description 45
- 239000005800 Kresoxim-methyl Substances 0.000 claims abstract description 41
- ZOTBXTZVPHCKPN-HTXNQAPBSA-N kresoxim-methyl Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=CC=C1C ZOTBXTZVPHCKPN-HTXNQAPBSA-N 0.000 claims abstract description 41
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 12
- 201000010099 disease Diseases 0.000 claims abstract description 11
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical compound C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims description 177
- 239000000843 powder Substances 0.000 claims description 35
- 238000009736 wetting Methods 0.000 claims description 31
- 239000000375 suspending agent Substances 0.000 claims description 23
- 230000000844 anti-bacterial effect Effects 0.000 claims description 20
- 239000000839 emulsion Substances 0.000 claims description 20
- 239000000725 suspension Substances 0.000 claims description 20
- 239000004562 water dispersible granule Substances 0.000 claims description 16
- 239000000945 filler Substances 0.000 claims description 7
- 239000012752 auxiliary agent Substances 0.000 claims description 4
- 239000000306 component Substances 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 235000013311 vegetables Nutrition 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 18
- 239000000575 pesticide Substances 0.000 abstract description 10
- 241000221785 Erysiphales Species 0.000 abstract description 9
- 241000223600 Alternaria Species 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 241000233679 Peronosporaceae Species 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 230000000855 fungicidal effect Effects 0.000 abstract description 2
- 238000001228 spectrum Methods 0.000 abstract description 2
- 241000395107 Cladosporium cucumerinum Species 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 239000000447 pesticide residue Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 33
- 239000002131 composite material Substances 0.000 description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 25
- 238000012360 testing method Methods 0.000 description 20
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 18
- 239000003795 chemical substances by application Substances 0.000 description 16
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 13
- 239000007859 condensation product Substances 0.000 description 11
- 239000002270 dispersing agent Substances 0.000 description 11
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 11
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 10
- 229910052799 carbon Inorganic materials 0.000 description 9
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- 229910021641 deionized water Inorganic materials 0.000 description 9
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- 231100000820 toxicity test Toxicity 0.000 description 8
- 241000255789 Bombyx mori Species 0.000 description 7
- 240000008067 Cucumis sativus Species 0.000 description 7
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- 208000003351 Melanosis Diseases 0.000 description 7
- 241000234295 Musa Species 0.000 description 7
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 7
- 239000002202 Polyethylene glycol Substances 0.000 description 7
- 235000014443 Pyrus communis Nutrition 0.000 description 7
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 7
- 239000002253 acid Substances 0.000 description 7
- 239000000440 bentonite Substances 0.000 description 7
- 229910000278 bentonite Inorganic materials 0.000 description 7
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 7
- 239000013530 defoamer Substances 0.000 description 7
- 230000000149 penetrating effect Effects 0.000 description 7
- 229920001223 polyethylene glycol Polymers 0.000 description 7
- 240000003377 Shepherdia canadensis Species 0.000 description 6
- 235000018324 Shepherdia canadensis Nutrition 0.000 description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 150000007513 acids Chemical class 0.000 description 6
- 150000004996 alkyl benzenes Chemical class 0.000 description 6
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 6
- 230000002528 anti-freeze Effects 0.000 description 6
- 239000011575 calcium Substances 0.000 description 6
- 229910052791 calcium Inorganic materials 0.000 description 6
- 239000006185 dispersion Substances 0.000 description 6
- 238000009313 farming Methods 0.000 description 6
- 235000019197 fats Nutrition 0.000 description 6
- 229920001296 polysiloxane Polymers 0.000 description 6
- 159000000000 sodium salts Chemical class 0.000 description 6
- 229920001285 xanthan gum Polymers 0.000 description 6
- 229920001732 Lignosulfonate Polymers 0.000 description 5
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 5
- 239000003905 agrochemical Substances 0.000 description 5
- 150000001298 alcohols Chemical class 0.000 description 5
- 229940077388 benzenesulfonate Drugs 0.000 description 5
- 239000011230 binding agent Substances 0.000 description 5
- 150000007942 carboxylates Chemical class 0.000 description 5
- 239000000470 constituent Substances 0.000 description 5
- 235000011187 glycerol Nutrition 0.000 description 5
- 239000008187 granular material Substances 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 229920005646 polycarboxylate Polymers 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 5
- 239000005995 Aluminium silicate Substances 0.000 description 4
- 206010067482 No adverse event Diseases 0.000 description 4
- 229910019142 PO4 Inorganic materials 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 235000012211 aluminium silicate Nutrition 0.000 description 4
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 239000007884 disintegrant Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000011835 investigation Methods 0.000 description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- 229920000609 methyl cellulose Polymers 0.000 description 4
- 239000001923 methylcellulose Substances 0.000 description 4
- 125000006353 oxyethylene group Chemical group 0.000 description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 4
- 239000010452 phosphate Substances 0.000 description 4
- 229920000573 polyethylene Polymers 0.000 description 4
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 4
- 229920002545 silicone oil Polymers 0.000 description 4
- 239000001488 sodium phosphate Substances 0.000 description 4
- 229910000162 sodium phosphate Inorganic materials 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 239000013638 trimer Substances 0.000 description 4
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 4
- 244000215068 Acacia senegal Species 0.000 description 3
- 229920000084 Gum arabic Polymers 0.000 description 3
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- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000000205 acacia gum Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 3
- 235000011130 ammonium sulphate Nutrition 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 229960000892 attapulgite Drugs 0.000 description 3
- 238000009833 condensation Methods 0.000 description 3
- 230000005494 condensation Effects 0.000 description 3
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
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- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 3
- 229910021653 sulphate ion Inorganic materials 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- RNMDNPCBIKJCQP-UHFFFAOYSA-N 5-nonyl-7-oxabicyclo[4.1.0]hepta-1,3,5-trien-2-ol Chemical compound C(CCCCCCCC)C1=C2C(=C(C=C1)O)O2 RNMDNPCBIKJCQP-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 125000002877 alkyl aryl group Chemical group 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
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- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 1
- YSUQLAYJZDEMOT-UHFFFAOYSA-N 2-(butoxymethyl)oxirane Chemical compound CCCCOCC1CO1 YSUQLAYJZDEMOT-UHFFFAOYSA-N 0.000 description 1
- CUFXMPWHOWYNSO-UHFFFAOYSA-N 2-[(4-methylphenoxy)methyl]oxirane Chemical compound C1=CC(C)=CC=C1OCC1OC1 CUFXMPWHOWYNSO-UHFFFAOYSA-N 0.000 description 1
- AOBIOSPNXBMOAT-UHFFFAOYSA-N 2-[2-(oxiran-2-ylmethoxy)ethoxymethyl]oxirane Chemical compound C1OC1COCCOCC1CO1 AOBIOSPNXBMOAT-UHFFFAOYSA-N 0.000 description 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 description 1
- JCUDAMKYTWVICI-UHFFFAOYSA-N 4-benzyl-2,3-dimethylphenol Chemical compound C1=C(O)C(C)=C(C)C(CC=2C=CC=CC=2)=C1 JCUDAMKYTWVICI-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 229920005682 EO-PO block copolymer Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- FQYUMYWMJTYZTK-UHFFFAOYSA-N Phenyl glycidyl ether Chemical compound C1OC1COC1=CC=CC=C1 FQYUMYWMJTYZTK-UHFFFAOYSA-N 0.000 description 1
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- 239000004283 Sodium sorbate Substances 0.000 description 1
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- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical class OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a sterilization composition containing imibenconazole and methoxyl acrylate compound, comprising an active component A and an active component B, wherein the active component A is selected from Imibenconazole and the active component B is respectively any one fungicide of kresoxim-methyl, kresoxim-methyl phenylate, pyraclostrobin and enestroburin, and the weight percents of the two active components are 1-50% and 1-60% respectively. The composition can control multiple crop diseases and has obvious synergistic effect, sterilization spectrum is expanded, and the composition has high activity on alternaria leaf spot, cladosporium cucumerinum, powdery mildew, leaf spot, downy mildew, epidemic disease and anthracnose; and meanwhile pesticide usage amount is reduced, pesticide residue on crop is reduced, and environmental pollution is reduced.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds.
Background technology
Glyoxalin, English name: imibenconazole, molecular formula: C
17H
13C
L3N
4S, chemical name: 4-benzyl chloride base N-(2,4 dichloro benzene base)-2 (1H-1,2,4-triazol-1-yl) thioacetamide ester, structural formula:
Glyoxalin is the broad spectrum activity triazole bactericidal agent.The main mechanism of action is to destroy and stop the biosynthesis of the after birth important composition composition ergosterol of threading of germ, thereby destroys the formation of cell membrane, causes germ death.Glyoxalin has protection and therapeutic action, can rapid osmotic after being sprayed onto on the crop in plant corpus, resistance of rainwater washing against.
Yet in the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect with glyoxalin and kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin after composite, and still unexposed about the composite relevant report of glyoxalin and kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin.
Summary of the invention
A kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B percentage by weight are 1～50%: 1～60%, active component A is selected from glyoxalin, and active component B is kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin.
Described a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds is characterized in that: the percentage by weight of A, two kinds of active components of B is 2～40%: 2～50%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and kresoxim-methyl is 5～30%: 5～40%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5～30%: 5～20%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and pyraclostrobin is 5～30%: 5～40%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and Enestroburin is 5～30%: 5～40%.
The percentage by weight of A, two kinds of active components of B is 1～50%: 1～60%.Usually active weight percentage is 0.5～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, binding agent or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether), farming newborn 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), farming newborn 36# (phenethyl fluosite polyoxy ethyl ether), farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether), farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), in the AEO series (the pure APEO of fat) one or more.
Described stabilizing agent is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, the polyethylene glycol diglycidyl ether;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent or suspension emulsion.
When making wetting powder, composition comprises following constituent content: glyoxalin 1～50%, active component B 1～60%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
Active component glyoxalin, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: active component glyoxalin 1～50%, active component B1～60%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
Active component glyoxalin, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
Comprise following constituent content when composition is made suspending agent: active component glyoxalin 1～25%, active component B1～35%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active component glyoxalin, active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is made suspension emulsion: glyoxalin 1～25%, effective active composition B 1～35%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of effective active composition B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the former medicine suspending agent of effective active composition B, then with the former medicine of glyoxalin, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
The invention has the advantages that: after (1) glyoxalin and effective active composition B are composite, have notable synergistic and lasting effect; (2) enlarged fungicidal spectrum, diseases such as spot defoliation, scab, powdery mildew, leaf spot, downy mildew, eqpidemic disease, anthracnose have all been had greater activity; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage; (4) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 60% glyoxalin kresoxim-methyl wetting powder
Glyoxalin 20%, kresoxim-methyl 40%, lignosulfonates 6%, wetting and penetrating agent F 4%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 60% glyoxalin kresoxim-methyl wetting powder.
Example 2 62% glyoxalin kresoxim-methyl wetting powders
Glyoxalin 2%, kresoxim-methyl 60%, alkyl benzene sulfonate calcium salt 7%, silkworm excrement 6%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 62% glyoxalin kresoxim-methyl wetting powder.
Example 3 50% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 10%, kresoxim-methyl 40%, spaonin powder 5%, polycarboxylate aliphatic amine polyoxyethylene are phonetic 5%, aluminium chloride 1.5%, bentonite add to 100%, mixed 50% glyoxalin water dispersion granules agent of Kresoxim.
Example 4 65% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 15%, kresoxim-methyl 50%, lauryl sodium sulfate 8%, polycarboxylate 6%, ammonium sulfate 1.6%, attapulgite add to 100%, the mixed 65% glyoxalin water dispersion granules agent of Kresoxim that gets.
Example 5 30% glyoxalin kresoxim-methyl suspending agents
Glyoxalin 10%, kresoxim-methyl 20%, polyoxyethylene carboxylate 6%, Nekal BX 5%, silicone oil 0.3%, sodium phosphate trimer 1.2%, polyethylene glycol 1.8%, deionized water add to 100%, the mixed 30% glyoxalin kresoxim-methyl suspending agent that gets.
Example 6 45% glyoxalin kresoxim-methyl suspending agents
Glyoxalin 5%, kresoxim-methyl 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, neopelex 4%, C
8～10Aliphatic alcohols 0.5%, gum Arabic 1.2%, ethylene glycol 1.4%, deionized water add to 100%, the mixed 45% glyoxalin kresoxim-methyl suspending agent that gets.
Example 7 35% glyoxalin kresoxim-methyl suspension emulsions
Glyoxalin 30%, kresoxim-methyl 5%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 4%, xanthans 1.5%, propane diols 1.6%, C
10～20Saturated fat acids 0.6%, Nongru-700 #6%, water add to 100%, the mixed 35% glyoxalin kresoxim-methyl suspension emulsion that gets.
Example 8 40% glyoxalin kresoxim-methyl suspension emulsions
Glyoxalin 10%, kresoxim-methyl 30%, octylphenol polyethylene oxyethylene group ether sulfate 7%, neopelex 5%, methylcellulose 1.4%, polyethylene glycol 1.3%, silicone compound 0.5%, agricultural newborn 1600#5%, water add to 100%, the mixed 40% glyoxalin kresoxim-methyl suspension emulsion that gets.
Example 9 45% glyoxalin ZJ0712 wetting powders
Glyoxalin 30%, ZJ0712 15%, polycarboxylate 7%, soapberry powder 6%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 45% glyoxalin ZJ0712 wetting powder.
Example 10 60% glyoxalin ZJ0712 wetting powders
Glyoxalin 40%, ZJ0712 20%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 5%, starch add to 100%, and mixture carries out comminution by gas stream, make 60% glyoxalin ZJ0712 wetting powder.
Example 11 30% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 20%, ZJ0712 10%, lignosulfonates 6%, Nekal BX 5%, ammonium sulfate 1.5%, kaolin add to 100%, the mixed 30% glyoxalin ZJ0712 water dispersible granules that gets.
Example 12 50% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 40%, ZJ0712 10%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, spaonin powder 4%, bentonite add to 100%, the mixed 50% glyoxalin ZJ0712 water dispersible granules that gets.
Example 13 20% glyoxalin ZJ0712 suspending agents
Glyoxalin 10%, ZJ0712 10%, alkylphenol-polyethenoxy are phonetic 7%, soapberry powder 6%, C
8～10Aliphatic alcohols 0.4%, sodium phosphate trimer 1.3%, glycerine 1.6%, deionized water add to 100%, the mixed 20% glyoxalin ZJ0712 suspending agent that gets.
Example 14 48% glyoxalin ZJ0712 suspending agents
Glyoxalin 16%, ZJ0712 32%, polyoxyethylene carboxylate 6%, lauryl sodium sulfate 4%, silicone oil 0.4%, xanthans 1.1%, polyethylene glycol 1.9%, deionized water add to 100%, the mixed 48% glyoxalin ZJ0712 suspending agent that gets.
Example 15 15% glyoxalin ZJ0712 suspension emulsions
Glyoxalin 5%, ZJ0712 10%, lignosulfonates 6%, wetting and penetrating agent F 5%, gum Arabic 1%, ethylene glycol 1.6%, C
10～20Saturated fat acids 0.4%, 600# phosphate 6%, water add to 100%, the mixed 15% glyoxalin ZJ0712 suspension emulsion that gets.
Example 16 45% glyoxalin ZJ0712 suspension emulsions
Glyoxalin 40%, ZJ0712 5%, octylphenol polyethylene oxyethylene group ether sulfate 5%, soapberry powder 4%, polyvinylpyrrolidone 1.5%, glycerine 1.2%, silicone compound 0.3%, agricultural newborn 500#5%, water add to 100%, the mixed 45% glyoxalin ZJ0712 suspension emulsion that gets.
Example 17 45% glyoxalin pyraclostrobin wetting powders
Glyoxalin 15%, pyraclostrobin 30%, polyoxyethylene carboxylate 6%, silkworm excrement 5%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 45% glyoxalin pyraclostrobin wetting powder.
Example 18 70% glyoxalin pyraclostrobin wetting powders
Glyoxalin 10%, pyraclostrobin 60%, alkyl benzene sulfonate calcium salt 8%, Nekal BX 6%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 70% glyoxalin pyraclostrobin wetting powder.
Example 19 42% glyoxalin pyraclostrobin water dispersible granules
Glyoxalin 20%, pyraclostrobin 22%, alkylphenol-polyethenoxy are phonetic 7%, lauryl sodium sulfate 5%, bentonite add to 100%, mixed 42% glyoxalin pyraclostrobin water dispersible granules.
Example 20 55% glyoxalin pyraclostrobin water dispersible granules
Glyoxalin 15%, pyraclostrobin 40%, polycarboxylate 6%, wetting and penetrating agent F4%, urea 1.3%, attapulgite add to 100%, the mixed 55% glyoxalin pyraclostrobin water dispersible granules that gets.
Example 21 10% glyoxalin pyraclostrobin suspending agents
Glyoxalin 5%, pyraclostrobin 5%, alkyl benzene sulfonate calcium salt 8%, neopelex 5%, C
8～10Aliphatic alcohols 0.5%, methylcellulose 1.6%, glycerine 1.8%, deionized water add to 100%, the mixed 10% glyoxalin pyraclostrobin suspending agent that gets.
Example 22 40% glyoxalin pyraclostrobin suspending agents
Glyoxalin 8%, pyraclostrobin 32%, the phonetic formaldehyde condensation products sulphate 7% of alkylphenol-polyethenoxy, silkworm excrement 5%, C
10～20Saturated fat acids 0.7%, xanthans 1.3%, ethylene glycol 1.7%, deionized water add to 100%, the mixed 40% glyoxalin pyraclostrobin suspending agent that gets.
Example 23 30% glyoxalin pyraclostrobin suspension emulsions
Glyoxalin 20%, pyraclostrobin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, soapberry powder 4%, methylcellulose 1.5%, ethylene glycol 1.4%, silicone compound 0.6%, agricultural newborn 1600#6%, water add to 100%, the mixed 30% glyoxalin pyraclostrobin suspension emulsion that gets.
Example 24 36% glyoxalin pyraclostrobin suspension emulsions
Glyoxalin 12%, pyraclostrobin 24%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, wetting and penetrating agent F 6%, xanthans 1.7%, propane diols 1.6%, C
10～20Saturated fat acids 0.4%, AEO series 5%, water add to 100%, the mixed 36% glyoxalin pyraclostrobin suspension emulsion that gets.
Example 25 55% glyoxalin Enestroburin wetting powders
Glyoxalin 10%, Enestroburin 45%, lignosulfonates 8%, Nekal BX 6%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 55% glyoxalin Enestroburin wetting powder.
Example 26 70% glyoxalin Enestroburin wetting powders
Glyoxalin 20%, Enestroburin 50%, polyoxyethylene carboxylate 6%, spaonin powder 5%, starch add to 100%, and mixture carries out comminution by gas stream, make 70% glyoxalin Enestroburin wetting powder.
Example 27 50% glyoxalin Enestroburin water dispersible granules
Glyoxalin 10%, Enestroburin 40%, octylphenol polyethylene oxyethylene group ether sulfate 5%, silkworm excrement 4%, aluminium chloride 1.5%, diatomite add to 100%, the mixed 50% glyoxalin Enestroburin water dispersible granules that gets.
Example 28 65% glyoxalin Enestroburin water dispersible granules
Glyoxalin 30%, Enestroburin 35%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, wetting and penetrating agent F 5%, bentonite add to 100%, the mixed 65% glyoxalin Enestroburin water dispersible granules that gets.
Example 29 15% glyoxalin Enestroburin suspending agents
Glyoxalin 10%, Enestroburin 5%, aliphatic amine polyoxyethylene are phonetic 7%, soapberry powder 5%, silicone oil 0.4%, sodium phosphate trimer 1.2%, polyethylene glycol 1.7%, deionized water add to 100%, mixed 15% glyoxalin Enestroburin suspending agent.
Example 30 45% glyoxalin Enestroburin suspending agents
Glyoxalin 15%, Enestroburin 30%, alkyl benzene sulfonate calcium salt 6%, lauryl sodium sulfate 4%, C
8～10Aliphatic alcohols 0.3%, xanthans 1.4%, glycerine 1.6%, deionized water add to 100%, the mixed 45% glyoxalin Enestroburin suspending agent that gets.
Example 31 16% glyoxalin Enestroburin suspension emulsions
Glyoxalin 8%, Enestroburin 8%, naphthalene sulfonic acid-formaldehyde condensation product 7%, wetting and penetrating agent F 5%, crospolyvinylpyrrolidone 1.3%, ethylene glycol 1.8%, C
10～20Saturated fat acids 0.5%, Nongru-700 #5%, water add to 100%, the mixed 16% glyoxalin Enestroburin suspension emulsion that gets.
Example 32 42% glyoxalin Enestroburin suspension emulsions
Glyoxalin 14%, Enestroburin 28%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, spaonin powder 4%, polyvinylpyrrolidone 1.7%, propane diols 1.2%, silicone compound 0.6%, agricultural newborn 1600#6%, water add to 100%, the mixed 42% glyoxalin Enestroburin suspension emulsion that gets.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Glyoxalin and active component B (B is selected from a kind of of kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component glyoxalin and B (kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) shared ratio in combination;
A is a glyoxalin;
B is a kind of in kresoxim-methyl, ZJ0712, pyraclostrobin, the Enestroburin.
Implementation of an application example diimine azoles and kresoxim-methyl are composite to the alternaria leaf spot of apple Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of kresoxim-methyl and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 glyoxalin, kresoxim-methyl and composite toxicity test analysis of results table thereof to alternaria leaf spot of apple
As shown in Table 1, glyoxalin, kresoxim-methyl are to the EC of alternaria leaf spot of apple
50Be respectively 0.68mg/L and 1.47mg/L.Glyoxalin and kresoxim-methyl proportioning were at 50: 1 to 1: 60 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and kresoxim-methyl were mixed in the scope at 50: 1 to 1: 60 all shows synergistic effect, especially when the two proportioning during at 2: 1 to 1: 8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and kresoxim-methyl weight ratio are 1: 2 wherein, synergistic effect is the most obvious.
Implementation of an application example three glyoxalins and ZJ0712 are composite to the powdery mildew of cucumber Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of ZJ0712 and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 glyoxalin, ZJ0712 and composite toxicity test analysis of results table thereof to powdery mildew of cucumber
As shown in Table 2, glyoxalin, ZJ0712 are to the EC of powdery mildew of cucumber
50Be respectively 0.76mg/L and 0.34mg/L.Glyoxalin and ZJ0712 proportioning were at 50: 1 to 1: 60 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and ZJ0712 were mixed in the scope at 50: 1 to 1: 60 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 2, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and ZJ0712 weight ratio are 2: 1 wherein, synergistic effect is the most obvious.
Implementation of an application example four
Glyoxalin and pyraclostrobin are composite to the banana freckle Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of pyraclostrobin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 glyoxalin, pyraclostrobin and composite toxicity test analysis of results table thereof to banana freckle
As shown in Table 3, glyoxalin, pyraclostrobin are to the EC of banana freckle
50Be respectively 0.71mg/L and 1.58mg/L.Glyoxalin and pyraclostrobin proportioning were at 50: 1 to 1: 60 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and pyraclostrobin were mixed in the scope at 50: 1 to 1: 60 all shows synergistic effect, especially when the two proportioning during at 2: 1 to 1: 8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and pyraclostrobin weight ratio are 1: 2 wherein, synergistic effect is the most obvious.
Implementation of an application example five:
Glyoxalin and Enestroburin are composite to the pear scab Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of Enestroburin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 4 glyoxalin, Enestroburin and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 4, glyoxalin, Enestroburin are to the EC of pear scab
50Be respectively 0.65mg/L and 1.42mg/L.Glyoxalin compares at 50: 1 to 1: 60 o'clock with Enestroburin, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and Enestroburin were mixed in the scope at 2: 1 to 1: 8 all shows synergistic effect, synergy ratio SR maximum when glyoxalin and Enestroburin weight ratio are 1: 2 wherein, synergistic effect is the most obvious.
Application Example six glyoxalins and kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Dali County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 50% water dispersion granules agent of Kresoxim (commercial).
The preceding investigation of medicine alternaria leaf spot of apple disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 5 glyoxalin, kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 5, can effectively prevent and treat alternaria leaf spot of apple after glyoxalin and kresoxim-methyl are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven glyoxalins and ZJ0712 and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in the Qingdao of Shandong province suburb, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 10% ZJ0712 suspending agent (commercial).
The investigation powdery mildew of cucumber state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 6 glyoxalin, ZJ0712 and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 6, can effectively prevent and treat powdery mildew of cucumber after glyoxalin and ZJ0712 are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight glyoxalins and pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
This experimental establishment is in Longan County, Guangxi province Nanning City, and test medicine is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 250 grams per liter pyraclostrobin missible oil (commercial).
The investigation banana freckle state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 10 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 7 glyoxalin, pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
As can be seen from Table 7, can effectively prevent and treat banana freckle after glyoxalin and pyraclostrobin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine glyoxalins and Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Pucheng County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 25% Enestroburin missible oil (commercial).
The preceding investigation of medicine pear scab disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 8 glyoxalin, Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 8, can effectively prevent and treat pear scab after glyoxalin and Enestroburin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (8)
1. bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: active component A, B percentage by weight are 1～50%: 1～60%, described active component A is selected from glyoxalin, and active component B is selected from a kind of in kresoxim-methyl, ZJ0712, pyraclostrobin, the Enestroburin.
2. a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds according to claim 1 is characterized in that: the percentage by weight of A, two kinds of active components of B is 2～40%: 2～50%.
3. the bactericidal composition that contains glyoxalin according to claim 2 is characterized in that: the percentage by weight of glyoxalin and kresoxim-methyl is 5～30%: 5～40%.
4. the bactericidal composition that contains glyoxalin according to claim 2 is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5～30%: 5～20%.
5. the bactericidal composition that contains glyoxalin according to claim 2 is characterized in that: the percentage by weight of glyoxalin and pyraclostrobin is 5～30%: 5～40%.
6. the bactericidal composition that contains glyoxalin according to claim 2 is characterized in that: the percentage by weight of glyoxalin and Enestroburin is 5～30%: 5～40%.
7. the bactericidal composition that contains glyoxalin according to claim 1 is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent or suspension emulsion.
8. the bactericidal composition that contains glyoxalin according to claim 1 is mainly used in control paddy rice, vegetables, fruit tree multiple diseases.
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| CN201110006168.XA CN102037969B (en) | 2011-01-12 | 2011-01-12 | Sterilization composition containing imibenconazole and methoxyl acrylate compound |
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| CN201310282898.1A Division CN103392719B (en) | 2011-01-12 | 2011-01-12 | Bactericidal composition containing iminazoles and methoxy acrylates |
| CN201310282450.XA Division CN103392709B (en) | 2011-01-12 | 2011-01-12 | Bactericidal composition containing iminazoles and methoxy acrylates |
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| CN102037969B CN102037969B (en) | 2014-06-18 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101087525A (en) * | 2004-12-23 | 2007-12-12 | 巴斯福股份公司 | Fungicidal mixtures containing enestroburin and at least one active substance from the group of azoles |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| WO2010094728A1 (en) * | 2009-02-19 | 2010-08-26 | Bayer Cropscience Ag | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101087525A (en) * | 2004-12-23 | 2007-12-12 | 巴斯福股份公司 | Fungicidal mixtures containing enestroburin and at least one active substance from the group of azoles |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| WO2010094728A1 (en) * | 2009-02-19 | 2010-08-26 | Bayer Cropscience Ag | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance |
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Inventor after: Yu Min Inventor after: Deng Song Inventor after: Liu An Inventor after: Deng Meng Inventor after: Xie Xiaoyang Inventor before: Zhang Wei Inventor before: Gao Chao Inventor before: Cao Qiaoli |
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