CN103392709B - Bactericidal composition containing iminazoles and methoxy acrylates - Google Patents
Bactericidal composition containing iminazoles and methoxy acrylates Download PDFInfo
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- CN103392709B CN103392709B CN201310282450.XA CN201310282450A CN103392709B CN 103392709 B CN103392709 B CN 103392709B CN 201310282450 A CN201310282450 A CN 201310282450A CN 103392709 B CN103392709 B CN 103392709B
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- glyoxalin
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- kresoxim
- enestroburin
- pyraclostrobin
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Abstract
The invention discloses a bactericidal composition containing iminazoles and methoxy acrylates, which contains 1-50 wt% of active component A and 1-60 wt% of active component B, wherein the active component A is selected from iminazoles; and the active component B is selected from any one of the following bactericides: kresoxim-methyl, strobilurin, pyraclostrobin and enestroburin. The bactericidal composition can be used for controlling multiple crop diseases, has obvious synergistic action, widens the bactericidal spectrum, and has higher activity for alternaria leaf spot, banana freckle, powdery mildew, leaf spot, downy mildew, epidemic disease and anthracnose; and the bactericidal composition reduces the amount of pesticide, lowers the residue level of the pesticide on the crops, and alleviates the environmental pollution.
Description
The application is divisional application, original application is the patent application " a kind of bactericidal composition containing glyoxalin and methoxy acrylic ester compounds " of Mei Bang agricultural chemicals Co., Ltd, the application number Wei ︰ 201110006168.X of original application, original application day is 2011.01.12.
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition containing glyoxalin and methoxy acrylic ester compounds.
Background technology
Glyoxalin, English name: imibenconazole, molecular formula: C
17h
13cl
3n
4s, chemical name: 4-chlorobenzyl N-(2,4-dichlorophenyl)-2 (1H-1,2,4-triazol-1-yl) thioacetamide ester, structural formula:
Glyoxalin is broad spectrum activity triazole bactericidal agent.Main Function mechanism is the biosynthesis of the after birth important composition composition ergosterol of threading destroying and stop germ, thus destroys the formation of cell membrane, causes germ dead.Glyoxalin has protection and therapeutic action, to be sprayed onto after on crop can rapid osmotic in plant corpus, resistance of rainwater washing against.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is the drug-fast generation of germ.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find by glyoxalin and kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin composite after can produce good synergistic effect, and about glyoxalin and the composite relevant report of kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin not yet open.
Summary of the invention
A kind of bactericidal composition containing glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B percentage by weight is 1 ~ 50% ︰ 1 ~ 60%, active component A is selected from glyoxalin, and active component B is kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin.
Described a kind of bactericidal composition containing glyoxalin and methoxy acrylic ester compounds, is characterized in that: the percentage by weight of A, B two kinds of active components is 2 ~ 40% ︰ 2 ~ 50%.
The described bactericidal composition containing glyoxalin, is characterized in that: the percentage by weight of glyoxalin and kresoxim-methyl is 5 ~ 30% ︰ 5 ~ 40%.
The described bactericidal composition containing glyoxalin, is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5 ~ 30% ︰ 5 ~ 20%.
The described bactericidal composition containing glyoxalin, is characterized in that: the percentage by weight of glyoxalin and pyraclostrobin is 5 ~ 30% ︰ 5 ~ 40%.
The described bactericidal composition containing glyoxalin, is characterized in that: the percentage by weight of glyoxalin and Enestroburin is 5 ~ 30% ︰ 5 ~ 40%.
The percentage by weight of A, B two kinds of active components is 1 ~ 50% ︰ 1 ~ 60%.Weight percentage active in usual composition is 0.5 ~ 90% of gross weight, is preferably 5% ~ 85%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains 1 ~ 70% active substance by weight, is preferably 5 ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5 ~ 85%, is preferably 10 ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5 ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, disintegrant known in those skilled in the art, antifreeze etc. can also be contained.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, one or more during ester polyoxyethylene is phonetic.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol.
Described defoamer is selected from: silicone, C
8 ~ 10aliphatic alcohols, C
10 ~ 20one or more in saturated fat acids (as capric acid) and acid amides, silicone oil, silicone compound.
Described emulsifier is selected from: agriculture breast 500#(alkyl benzene calcium sulfonate), OP series phosphate (thermally coupled distillation columns), 600# phosphate (phenyl phenol polyoxyethanyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400#(benzyl dimethyl phenol polyoxyethyl ether), agriculture breast 600#(phenyl phenol polyoxyethyl ether), Nongru-700 #(alkylphenol-formaldehyde resin polyoxyethyl ether), agriculture breast 36#(phenethyl fluosite polyoxyethyl ether), agriculture breast 1600#(phenethyl phenol polyoxyethanyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), agriculture breast 33#(alkylaryl polyoxyethylene polyoxypropylene ether), agriculture breast 34#(alkylaryl polyoxyethylene poly-oxygen propylene aether), Span series (sorbitan monostearate), TWEEN Series (sorbitan fatty acid ester APEO), one or more in AEO series (fat alcohol alcohol APEO).
Described stabilizing agent be selected from sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, polyethylene glycol diglycidyl ether one or more;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
Composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method, after mixing, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, adhesive, defoamer etc. by active substance with liquid flux or solid carrier.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent or suspension emulsion.
Composition comprises following constituent content when making wetting powder: glyoxalin 1 ~ 50%, active component B1 ~ 60%, dispersant 5 ~ 10%, wetting agent 2 ~ 10%, filler 8 ~ 91%.
By active component glyoxalin, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into the wetting powder product of the present composition.
Composition comprises following constituent content when making water dispersible granules: active component glyoxalin 1 ~ 50%, active component B1 ~ 60%, dispersant 3 ~ 12%, wetting agent 1 ~ 8%, disintegrant 1 ~ 10%, binding agent 1 ~ 8%, filler 10 ~ 92%.
Active component glyoxalin, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent, obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, obtaining the water dispersible granules product of the present composition.
Composition comprises following constituent content when making suspending agent: active component glyoxalin 1 ~ 25%, active component B1 ~ 35%, dispersant 2 ~ 10%, wetting agent 2 ~ 10%, defoamer 0.1 ~ 1%, binding agent 0.1 ~ 2%, antifreeze 0.1 ~ 8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in above-mentioned formulation material are mixed through high speed shear, add active component glyoxalin, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, the suspending agent product of the obtained present composition.
Composition comprises following constituent content when making suspension emulsion: glyoxalin 1 ~ 25%, effective active composition B1 ~ 35%, emulsifier 2 ~ 12%, dispersant 2 ~ 10%, defoamer 0.1 ~ 2%, thickener 0.1 ~ 2%, antifreeze 0.1 ~ 8%, stabilizing agent 0.05 ~ 3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in above-mentioned formulation material are mixed through high speed shear, add the former medicine of effective active composition B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, the obtained former medicine suspending agent of effective active composition B, then by former for glyoxalin medicine, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, the suspension emulsion product of the obtained present composition.
The invention has the advantages that: (1) glyoxalin and effective active composition B composite after, there is notable synergistic and lasting effect; (2) expand fungicidal spectrum, all have greater activity to diseases such as spot defoliation, scab, powdery mildew, leaf spot, downy mildew, epidemic disease, anthracnose; (3) the present invention not with an organic solvent, not easily produces poisoning, is convenient to transport and storage; (4) decrease the dosage of agricultural chemicals, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.
Application Example one
Example 1 60% glyoxalin kresoxim-methyl wetting powder
Glyoxalin 20%, kresoxim-methyl 40%, lignosulfonates 6%, wetting and penetrating agent F4%, kaolin add to 100%, and mixture carries out air-flow crushing, obtained 60% glyoxalin kresoxim-methyl wetting powder.
Example 2 62% glyoxalin kresoxim-methyl wetting powder
Glyoxalin 2%, kresoxim-methyl 60%, alkyl benzene sulfonate calcium salt 7%, silkworm excrement 6%, diatomite add to 100%, and mixture carries out air-flow crushing, obtained 62% glyoxalin kresoxim-methyl wetting powder.
Example 3 50% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 10%, kresoxim-methyl 40%, spaonin powder 5%, polycarboxylate aliphatic amine polyoxyethylene are phonetic 5%, aluminium chloride 1.5%, bentonite add to 100%, the obtained 50% glyoxalin water dispersion granules agent of Kresoxim of mixing.
Example 4 65% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 15%, kresoxim-methyl 50%, lauryl sodium sulfate 8%, polycarboxylate 6%, ammonium sulfate 1.6%, attapulgite add to 100%, the obtained 65% glyoxalin water dispersion granules agent of Kresoxim of mixing.
Example 5 30% glyoxalin kresoxim-methyl suspending agent
Glyoxalin 10%, kresoxim-methyl 20%, polyoxyethylene carboxylate 6%, Nekal BX 5%, silicone oil 0.3%, sodium phosphate trimer 1.2%, polyethylene glycol 1.8%, deionized water add to 100%, the obtained 30% glyoxalin kresoxim-methyl suspending agent of mixing.
Example 6 45% glyoxalin kresoxim-methyl suspending agent
Glyoxalin 5%, kresoxim-methyl 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, neopelex 4%, C
8 ~ 10aliphatic alcohols 0.5%, gum Arabic 1.2%, ethylene glycol 1.4%, deionized water add to 100%, the obtained 45% glyoxalin kresoxim-methyl suspending agent of mixing.
Example 7 35% glyoxalin kresoxim-methyl suspension emulsion
Glyoxalin 30%, kresoxim-methyl 5%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 4%, xanthans 1.5%, propane diols 1.6%, C
10 ~ 20saturated fat acids 0.6%, Nongru-700 #6%, water add to 100%, the obtained 35% glyoxalin kresoxim-methyl suspension emulsion of mixing.
Example 8 40% glyoxalin kresoxim-methyl suspension emulsion
Glyoxalin 10%, kresoxim-methyl 30%, octylphenol polyethylene oxyethylene group ether sulfate 7%, neopelex 5%, methylcellulose 1.4%, polyethylene glycol 1.3%, silicone compound 0.5%, agriculture breast 1600#5%, water add to 100%, the obtained 40% glyoxalin kresoxim-methyl suspension emulsion of mixing.
Example 9 45% glyoxalin ZJ0712 wetting powder
Glyoxalin 30%, ZJ0712 15%, polycarboxylate 7%, soapberry powder 6%, diatomite add to 100%, and mixture carries out air-flow crushing, obtained 45% glyoxalin ZJ0712 wetting powder.
Example 10 60% glyoxalin ZJ0712 wetting powder
Glyoxalin 40%, ZJ0712 20%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 5%, starch add to 100%, and mixture carries out air-flow crushing, obtained 60% glyoxalin ZJ0712 wetting powder.
Example 11 30% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 20%, ZJ0712 10%, lignosulfonates 6%, Nekal BX 5%, ammonium sulfate 1.5%, kaolin add to 100%, the obtained 30% glyoxalin ZJ0712 water dispersible granules of mixing.
Example 12 50% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 40%, ZJ0712 10%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, spaonin powder 4%, bentonite add to 100%, the obtained 50% glyoxalin ZJ0712 water dispersible granules of mixing.
Example 13 20% glyoxalin ZJ0712 suspending agent
Glyoxalin 10%, ZJ0712 10%, alkylphenol-polyethenoxy are phonetic 7%, soapberry powder 6%, C
8 ~ 10aliphatic alcohols 0.4%, sodium phosphate trimer 1.3%, glycerine 1.6%, deionized water add to 100%, the obtained 20% glyoxalin ZJ0712 suspending agent of mixing.
Example 14 48% glyoxalin ZJ0712 suspending agent
Glyoxalin 16%, ZJ0712 32%, polyoxyethylene carboxylate 6%, lauryl sodium sulfate 4%, silicone oil 0.4%, xanthans 1.1%, polyethylene glycol 1.9%, deionized water add to 100%, the obtained 48% glyoxalin ZJ0712 suspending agent of mixing.
Example 15 15% glyoxalin ZJ0712 suspension emulsion
Glyoxalin 5%, ZJ0712 10%, lignosulfonates 6%, wetting and penetrating agent F5%, gum Arabic 1%, ethylene glycol 1.6%, C
10 ~ 20saturated fat acids 0.4%, 600# phosphate 6%, water add to 100%, the obtained 15% glyoxalin ZJ0712 suspension emulsion of mixing.
Example 16 45% glyoxalin ZJ0712 suspension emulsion
Glyoxalin 40%, ZJ0712 5%, octylphenol polyethylene oxyethylene group ether sulfate 5%, soapberry powder 4%, polyvinylpyrrolidone 1.5%, glycerine 1.2%, silicone compound 0.3%, agriculture breast 500#5%, water add to 100%, the obtained 45% glyoxalin ZJ0712 suspension emulsion of mixing.
Example 17 45% glyoxalin pyraclostrobin wetting powder
Glyoxalin 15%, pyraclostrobin 30%, polyoxyethylene carboxylate 6%, silkworm excrement 5%, kaolin add to 100%, and mixture carries out air-flow crushing, obtained 45% glyoxalin pyraclostrobin wetting powder.
Example 18 70% glyoxalin pyraclostrobin wetting powder
Glyoxalin 10%, pyraclostrobin 60%, alkyl benzene sulfonate calcium salt 8%, Nekal BX 6%, diatomite add to 100%, and mixture carries out air-flow crushing, obtained 70% glyoxalin pyraclostrobin wetting powder.
Example 19 42% glyoxalin pyraclostrobin water dispersible granule
Glyoxalin 20%, pyraclostrobin 22%, alkylphenol-polyethenoxy are phonetic 7%, lauryl sodium sulfate 5%, bentonite add to 100%, the obtained 42% glyoxalin pyraclostrobin water dispersible granule of mixing.
Example 20 55% glyoxalin pyraclostrobin water dispersible granule
Glyoxalin 15%, pyraclostrobin 40%, polycarboxylate 6%, wetting and penetrating agent F4%, urea 1.3%, attapulgite add to 100%, the obtained 55% glyoxalin pyraclostrobin water dispersible granule of mixing.
Example 21 10% glyoxalin pyraclostrobin suspending agent
Glyoxalin 5%, pyraclostrobin 5%, alkyl benzene sulfonate calcium salt 8%, neopelex 5%, C
8 ~ 10aliphatic alcohols 0.5%, methylcellulose 1.6%, glycerine 1.8%, deionized water add to 100%, the obtained 10% glyoxalin pyraclostrobin suspending agent of mixing.
Example 22 40% glyoxalin pyraclostrobin suspending agent
The phonetic formaldehyde condensation products sulphate 7% of glyoxalin 8%, pyraclostrobin 32%, alkylphenol-polyethenoxy, silkworm excrement 5%, C
10 ~ 20saturated fat acids 0.7%, xanthans 1.3%, ethylene glycol 1.7%, deionized water add to 100%, the obtained 40% glyoxalin pyraclostrobin suspending agent of mixing.
Example 23 30% glyoxalin pyraclostrobin suspension emulsion
Glyoxalin 20%, pyraclostrobin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, soapberry powder 4%, methylcellulose 1.5%, ethylene glycol 1.4%, silicone compound 0.6%, agriculture breast 1600#6%, water add to 100%, the obtained 30% glyoxalin pyraclostrobin suspension emulsion of mixing.
Example 24 36% glyoxalin pyraclostrobin suspension emulsion
Glyoxalin 12%, pyraclostrobin 24%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, wetting and penetrating agent F6%, xanthans 1.7%, propane diols 1.6%, C
10 ~ 20saturated fat acids 0.4%, AEO series 5%, water add to 100%, the obtained 36% glyoxalin pyraclostrobin suspension emulsion of mixing.
Example 25 55% glyoxalin Enestroburin wetting powder
Glyoxalin 10%, Enestroburin 45%, lignosulfonates 8%, Nekal BX 6%, bentonite add to 100%, and mixture carries out air-flow crushing, obtained 55% glyoxalin Enestroburin wetting powder.
Example 26 70% glyoxalin Enestroburin wetting powder
Glyoxalin 20%, Enestroburin 50%, polyoxyethylene carboxylate 6%, spaonin powder 5%, starch add to 100%, and mixture carries out air-flow crushing, obtained 70% glyoxalin Enestroburin wetting powder.
Example 27 50% glyoxalin Enestroburin water dispersible granules
Glyoxalin 10%, Enestroburin 40%, octylphenol polyethylene oxyethylene group ether sulfate 5%, silkworm excrement 4%, aluminium chloride 1.5%, diatomite add to 100%, the obtained 50% glyoxalin Enestroburin water dispersible granules of mixing.
Example 28 65% glyoxalin Enestroburin water dispersible granules
Glyoxalin 30%, Enestroburin 35%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, wetting and penetrating agent F5%, bentonite add to 100%, the obtained 65% glyoxalin Enestroburin water dispersible granules of mixing.
Example 29 15% glyoxalin Enestroburin suspending agent
Glyoxalin 10%, Enestroburin 5%, aliphatic amine polyoxyethylene are phonetic 7%, soapberry powder 5%, silicone oil 0.4%, sodium phosphate trimer 1.2%, polyethylene glycol 1.7%, deionized water add to 100%, the obtained 15% glyoxalin Enestroburin suspending agent of mixing.
Example 30 45% glyoxalin Enestroburin suspending agent
Glyoxalin 15%, Enestroburin 30%, alkyl benzene sulfonate calcium salt 6%, lauryl sodium sulfate 4%, C
8 ~ 10aliphatic alcohols 0.3%, xanthans 1.4%, glycerine 1.6%, deionized water add to 100%, the obtained 45% glyoxalin Enestroburin suspending agent of mixing.
Example 31 16% glyoxalin Enestroburin suspension emulsion
Glyoxalin 8%, Enestroburin 8%, naphthalene sulfonic acid-formaldehyde condensation product 7%, wetting and penetrating agent F5%, crospolyvinylpyrrolidone 1.3%, ethylene glycol 1.8%, C
10 ~ 20saturated fat acids 0.5%, Nongru-700 #5%, water add to 100%, the obtained 16% glyoxalin Enestroburin suspension emulsion of mixing.
Example 32 42% glyoxalin Enestroburin suspension emulsion
The phonetic formaldehyde condensation products sulphate 6% of glyoxalin 14%, Enestroburin 28%, alkylphenol-polyethenoxy, spaonin powder 4%, polyvinylpyrrolidone 1.7%, propane diols 1.2%, silicone compound 0.6%, agriculture breast 1600#6%, water add to 100%, the obtained 42% glyoxalin Enestroburin suspension emulsion of mixing.
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Glyoxalin and active component B(B are selected from the one of kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) composite to crop pest Toxicity Determination.
Determine that after the effective inhibition concentration scope of each medicament, each medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component glyoxalin and B(kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) shared in combination ratio;
A is glyoxalin;
B is the one in kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin.
Implementation of an application example diimine azoles and kresoxim-methyl composite to alternaria leaf spot of apple Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination glyoxalin, the former medicine of kresoxim-methyl and the two different ratio mixture.
Toxicity test result
Table 1 glyoxalin, kresoxim-methyl and the composite toxicity test analysis of results table to alternaria leaf spot of apple thereof
As shown in Table 1, glyoxalin, kresoxim-methyl are to the EC of alternaria leaf spot of apple
50be respectively 0.68mg/L and 1.47mg/L.Glyoxalin and kresoxim-methyl proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and kresoxim-methyl mixture in 50 ︰ 1 to 1 ︰ 60 scopes all shows synergistic effect, especially when the proportioning of the two is at 2:1 to 1:8, synergistic effect is more obviously given prominence to, wherein when glyoxalin and kresoxim-methyl weight ratio are 1 ︰ 2, synergy ratio SR is maximum, and synergistic effect is the most obvious.
Implementation of an application example three glyoxalin and ZJ0712 composite to powdery mildew of cucumber Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination glyoxalin, the former medicine of ZJ0712 and the two different ratio mixture.
Toxicity test result
Table 2 glyoxalin, ZJ0712 and the composite toxicity test analysis of results table to powdery mildew of cucumber thereof
As shown in Table 2, glyoxalin, ZJ0712 are to the EC of powdery mildew of cucumber
50be respectively 0.76mg/L and 0.34mg/L.Glyoxalin and ZJ0712 proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and ZJ0712 mixture in 50 ︰ 1 to 1 ︰ 60 scopes all shows synergistic effect, especially when the proportioning of the two is at 8:1 to 1:2, synergistic effect is more obviously given prominence to, wherein when glyoxalin and ZJ0712 weight ratio are 2 ︰ 1, synergy ratio SR is maximum, and synergistic effect is the most obvious.
Implementation of an application example four
Glyoxalin and pyraclostrobin composite to banana freckle Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination glyoxalin, the former medicine of pyraclostrobin and the two different ratio mixture.
Toxicity test result
Table 3 glyoxalin, pyraclostrobin and the composite toxicity test analysis of results table to banana freckle thereof
As shown in Table 3, glyoxalin, pyraclostrobin are to the EC of banana freckle
50be respectively 0.71mg/L and 1.58mg/L.Glyoxalin and pyraclostrobin proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and pyraclostrobin mixture in 50 ︰ 1 to 1 ︰ 60 scopes all shows synergistic effect, especially when the proportioning of the two is at 2:1 to 1:8, synergistic effect is more obviously given prominence to, wherein when glyoxalin and pyraclostrobin weight ratio are 1 ︰ 2, synergy ratio SR is maximum, and synergistic effect is the most obvious.
Implementation of an application example five:
Glyoxalin and Enestroburin composite to pear scab Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination glyoxalin, the former medicine of Enestroburin and the two different ratio mixture.
Toxicity test result
Table 4 glyoxalin, Enestroburin and the composite toxicity test analysis of results table to pear scab thereof
As shown in Table 4, glyoxalin, Enestroburin are to the EC of pear scab
50be respectively 0.65mg/L and 1.42mg/L.Glyoxalin and Enestroburin compare when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and Enestroburin mixture in 2 ︰ 1 to 1 ︰ 8 scopes all shows synergistic effect, wherein when glyoxalin and Enestroburin weight ratio are 1 ︰ 2, synergy ratio SR is maximum, and synergistic effect is the most obvious.
Application Example six glyoxalin and kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Dali County, Shaanxi Province, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 5% glyoxalin wetting powder (commercial), 50% water dispersion granules agent of Kresoxim (commercial).
Investigation alternaria leaf spot of apple disease index before medicine, in their early stage dispenser, second time dispenser afterwards, altogether dispenser 2 times on the 10th, 7 days, 14 days investigation disease indexs after second time dispenser also calculate preventive effect.Experimental result is as follows:
Table 5 glyoxalin, kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 5, glyoxalin and kresoxim-methyl composite after effectively can prevent and treat alternaria leaf spot of apple, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Application Example seven glyoxalin and ZJ0712 and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
This experimental establishment is in suburb, Qingdao of Shandong province, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 5% glyoxalin wetting powder (commercial), 10% ZJ0712 suspending agent (commercial).
The investigation powdery mildew of cucumber state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 6 glyoxalin, ZJ0712 and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 6, glyoxalin and ZJ0712 composite after effectively can prevent and treat powdery mildew of cucumber, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Application Example eight glyoxalin and pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
This experimental establishment is in Longan County, Guangxi province Nanning City, and test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd., contrast medicament 5% glyoxalin wetting powder (commercial), 250 grams per liter pyraclostrobin missible oil (commercial).
The investigation banana freckle state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 10 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 7 glyoxalin, pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
As can be seen from Table 7, glyoxalin and pyraclostrobin composite after effectively can prevent and treat banana freckle, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Application Example nine glyoxalin and Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Pucheng County, Shaanxi Province, and test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 5% glyoxalin wetting powder (commercial), 25% Enestroburin missible oil (commercial).
Investigation pear scab disease index before medicine, in their early stage dispenser, second time dispenser afterwards, altogether dispenser 2 times on the 10th, 7 days, 14 days investigation disease indexs after second time dispenser also calculate preventive effect.Experimental result is as follows:
Table 8 glyoxalin, Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 8, glyoxalin and Enestroburin composite after effectively can prevent and treat pear scab, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Claims (5)
1. one kind contains the bactericidal composition of glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: effective active composition is made up of glyoxalin and ZJ0712, glyoxalin and ZJ0712 percentage by weight are 1% ~ 50% ︰ 1% ~ 60%.
2. a kind of bactericidal composition containing glyoxalin and methoxy acrylic ester compounds according to claim 1, is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 2% ~ 40% ︰ 2% ~ 50%.
3. the bactericidal composition containing glyoxalin according to claim 2, is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5% ~ 30% ︰ 5% ~ 20%.
4. the bactericidal composition containing glyoxalin according to claim 1, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent or suspension emulsion.
5. the bactericidal composition containing glyoxalin according to claim 1 is for preventing and treating the purposes of powdery mildew.
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| CN101167455A (en) * | 2007-12-06 | 2008-04-30 | 张少武 | Imibenconazole water dispersible granule and preparation method thereof |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN101715771A (en) * | 2009-11-30 | 2010-06-02 | 福建新农大正生物工程有限公司 | Sterilizing composition containing imibenconazole |
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| CN101167455A (en) * | 2007-12-06 | 2008-04-30 | 张少武 | Imibenconazole water dispersible granule and preparation method thereof |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN101715771A (en) * | 2009-11-30 | 2010-06-02 | 福建新农大正生物工程有限公司 | Sterilizing composition containing imibenconazole |
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