CN103392709A - Bactericidal composition containing iminazoles and methoxy acrylates - Google Patents
Bactericidal composition containing iminazoles and methoxy acrylates Download PDFInfo
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- CN103392709A CN103392709A CN201310282450XA CN201310282450A CN103392709A CN 103392709 A CN103392709 A CN 103392709A CN 201310282450X A CN201310282450X A CN 201310282450XA CN 201310282450 A CN201310282450 A CN 201310282450A CN 103392709 A CN103392709 A CN 103392709A
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- glyoxalin
- bactericidal composition
- kresoxim
- enestroburin
- pyraclostrobin
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Abstract
The invention discloses a bactericidal composition containing iminazoles and methoxy acrylates, which contains 1-50 wt% of active component A and 1-60 wt% of active component B, wherein the active component A is selected from iminazoles; and the active component B is selected from any one of the following bactericides: kresoxim-methyl, strobilurin, pyraclostrobin and enestroburin. The bactericidal composition can be used for controlling multiple crop diseases, has obvious synergistic action, widens the bactericidal spectrum, and has higher activity for alternaria leaf spot, banana freckle, powdery mildew, leaf spot, downy mildew, epidemic disease and anthracnose; and the bactericidal composition reduces the amount of pesticide, lowers the residue level of the pesticide on the crops, and alleviates the environmental pollution.
Description
The application is for dividing an application, original application is the patent application " a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds " of agricultural chemicals Co., Ltd of U.S. nation, the application number Wei ︰ 201110006168.X of original application, original application day is 2011.01.12.
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds.
Background technology
Glyoxalin, English name: imibenconazole, molecular formula: C
17H
13Cl
3N
4S, chemical name: 4-chlorobenzyl N-(2,4-dichlorophenyl)-2 (1H-1,2,4-triazol-1-yl) thioacetamide ester, structural formula:
Glyoxalin is the broad spectrum activity triazole bactericidal agent.Main Function mechanism is to destroy and stop the biosynthesis of the after birth important composition composition ergosterol of threading of germ, thereby destroys the formation of cell membrane, causes germ death.Glyoxalin has protection and therapeutic action, can rapid osmotic after being sprayed onto on crop in plant corpus, resistance of rainwater washing against.
Yet in the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect by glyoxalin and kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin after composite, and not yet open about glyoxalin and the composite relevant report of kresoxim-methyl, ZJ0712, pyraclostrobin and Enestroburin.
Summary of the invention
A kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B percentage by weight are 1～50% ︰ 1～60%, active component A is selected from glyoxalin, and active component B is kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin.
Described a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds is characterized in that: the percentage by weight of A, two kinds of active components of B is 2～40% ︰ 2～50%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and kresoxim-methyl is 5～30% ︰ 5～40%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5～30% ︰ 5～20%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and pyraclostrobin is 5～30% ︰ 5～40%.
The described bactericidal composition that contains glyoxalin is characterized in that: the percentage by weight of glyoxalin and Enestroburin is 5～30% ︰ 5～40%.
The percentage by weight of A, two kinds of active components of B is 1～50% ︰ 1～60%.Usually in composition, active weight percentage is 0.5～90% of gross weight, is preferably 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, is preferably 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, is preferably 10～80%.
In bactericidal composition of the present invention, contain at least a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, can also contain disintegrant known in those skilled in the art, antifreeze etc.
described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, one or more during the ester polyoxyethylene is phonetic.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20One or more in saturated fat acids (as capric acid) and acid amides, silicone oil, silicone compound.
described emulsifier is selected from: agriculture breast 500#(alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400#(benzyl dimethyl phenol polyoxy ethyl ether), agriculture breast 600#(phenyl phenol polyoxy ethyl ether), Nongru-700 #(alkylphenol-formaldehyde resin polyoxy ethyl ether), agriculture breast 36#(phenethyl fluosite polyoxy ethyl ether), agriculture breast 1600#(phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), agriculture breast 33#(alkylaryl polyoxyethylene polyoxypropylene ether), agriculture breast 34#(alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), one or more in AEO series (the pure APEO of fat).
Described stabilizing agent is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, polyethylene glycol diglycidyl ether;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, then adds one or more in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, defoamer etc.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent or suspension emulsion.
When making wetting powder, composition comprises following constituent content: glyoxalin 1～50%, active component B1～60%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
Active component glyoxalin, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, namely can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: active component glyoxalin 1～50%, active component B1～60%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
Active component glyoxalin, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter that needs through air-flow crushing together, then add other auxiliary agent such as binding agent, obtain the materials of granulating.By item quantitatively send in the fluidized bed granulation dryer through granulation and drying after, make the water dispersible granules product of the present composition.
When composition is made suspending agent, comprise following constituent content: active component glyoxalin 1～25%, active component B1～35%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in above-mentioned formulation material are mixed through high speed shear, add active component glyoxalin, active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
When composition is made suspension emulsion, comprise following constituent content: glyoxalin 1～25%, effective active composition B1～35%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in above-mentioned formulation material are mixed through high speed shear, add the former medicine of effective active composition B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the former medicine suspending agent of effective active composition B, then by the former medicine of glyoxalin, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
The invention has the advantages that: after (1) glyoxalin and effective active composition B are composite, have notable synergistic and lasting effect; (2) enlarged fungicidal spectrum, the diseases such as spot defoliation, scab, powdery mildew, leaf spot, downy mildew, epidemic disease, anthracnose have all been had to greater activity; (3) the present invention not with an organic solvent, is difficult for producing poisoning, is convenient to transportation and storage; (4) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution.
Embodiment
To further instruction of the present invention, the percentage in embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 60% glyoxalin kresoxim-methyl wetting powder
Glyoxalin 20%, kresoxim-methyl 40%, lignosulfonates 6%, wetting and penetrating agent F4%, kaolin add to 100%, and mixture carries out air-flow crushing, make 60% glyoxalin kresoxim-methyl wetting powder.
Example 2 62% glyoxalin kresoxim-methyl wetting powders
Glyoxalin 2%, kresoxim-methyl 60%, alkyl benzene sulfonate calcium salt 7%, silkworm excrement 6%, diatomite add to 100%, and mixture carries out air-flow crushing, make 62% glyoxalin kresoxim-methyl wetting powder.
Example 3 50% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 10%, kresoxim-methyl 40%, spaonin powder 5%, polycarboxylate aliphatic amine polyoxyethylene are phonetic 5%, aluminium chloride 1.5%, bentonite add to 100%, mix and make 50% glyoxalin water dispersion granules agent of Kresoxim.
Example 4 65% glyoxalin water dispersion granules agent of Kresoxim
Glyoxalin 15%, kresoxim-methyl 50%, lauryl sodium sulfate 8%, polycarboxylate 6%, ammonium sulfate 1.6%, attapulgite add to 100%, mix and make 65% glyoxalin water dispersion granules agent of Kresoxim.
Example 5 30% glyoxalin kresoxim-methyl suspending agents
Glyoxalin 10%, kresoxim-methyl 20%, polyoxyethylene carboxylate 6%, Nekal BX 5%, silicone oil 0.3%, sodium phosphate trimer 1.2%, polyethylene glycol 1.8%, deionized water add to 100%, mix and make 30% glyoxalin kresoxim-methyl suspending agent.
Example 6 45% glyoxalin kresoxim-methyl suspending agents
Glyoxalin 5%, kresoxim-methyl 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, neopelex 4%, C
8～10Aliphatic alcohols 0.5%, gum Arabic 1.2%, ethylene glycol 1.4%, deionized water add to 100%, mix and make 45% glyoxalin kresoxim-methyl suspending agent.
Example 7 35% glyoxalin kresoxim-methyl suspension emulsions
Glyoxalin 30%, kresoxim-methyl 5%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 4%, xanthans 1.5%, propane diols 1.6%, C
10～20Saturated fat acids 0.6%, Nongru-700 #6%, water add to 100%, mix and make 35% glyoxalin kresoxim-methyl suspension emulsion.
Example 8 40% glyoxalin kresoxim-methyl suspension emulsions
Glyoxalin 10%, kresoxim-methyl 30%, octylphenol polyethylene oxyethylene group ether sulfate 7%, neopelex 5%, methylcellulose 1.4%, polyethylene glycol 1.3%, silicone compound 0.5%, agriculture breast 1600#5%, water add to 100%, mix and make 40% glyoxalin kresoxim-methyl suspension emulsion.
Example 9 45% glyoxalin ZJ0712 wetting powders
Glyoxalin 30%, ZJ0712 15%, polycarboxylate 7%, soapberry powder 6%, diatomite add to 100%, and mixture carries out air-flow crushing, make 45% glyoxalin ZJ0712 wetting powder.
Example 10 60% glyoxalin ZJ0712 wetting powders
Glyoxalin 40%, ZJ0712 20%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, silkworm excrement 5%, starch add to 100%, and mixture carries out air-flow crushing, make 60% glyoxalin ZJ0712 wetting powder.
Example 11 30% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 20%, ZJ0712 10%, lignosulfonates 6%, Nekal BX 5%, ammonium sulfate 1.5%, kaolin add to 100%, mix and make 30% glyoxalin ZJ0712 water dispersible granules.
Example 12 50% glyoxalin ZJ0712 water dispersible granules
Glyoxalin 40%, ZJ0712 10%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, spaonin powder 4%, bentonite add to 100%, mix and make 50% glyoxalin ZJ0712 water dispersible granules.
Example 13 20% glyoxalin ZJ0712 suspending agents
Glyoxalin 10%, ZJ0712 10%, alkylphenol-polyethenoxy are phonetic 7%, soapberry powder 6%, C
8～10Aliphatic alcohols 0.4%, sodium phosphate trimer 1.3%, glycerine 1.6%, deionized water add to 100%, mix and make 20% glyoxalin ZJ0712 suspending agent.
Example 14 48% glyoxalin ZJ0712 suspending agents
Glyoxalin 16%, ZJ0712 32%, polyoxyethylene carboxylate 6%, lauryl sodium sulfate 4%, silicone oil 0.4%, xanthans 1.1%, polyethylene glycol 1.9%, deionized water add to 100%, mix and make 48% glyoxalin ZJ0712 suspending agent.
Example 15 15% glyoxalin ZJ0712 suspension emulsions
Glyoxalin 5%, ZJ0712 10%, lignosulfonates 6%, wetting and penetrating agent F5%, gum Arabic 1%, ethylene glycol 1.6%, C
10～20Saturated fat acids 0.4%, 600# phosphate 6%, water add to 100%, mix and make 15% glyoxalin ZJ0712 suspension emulsion.
Example 16 45% glyoxalin ZJ0712 suspension emulsions
Glyoxalin 40%, ZJ0712 5%, octylphenol polyethylene oxyethylene group ether sulfate 5%, soapberry powder 4%, polyvinylpyrrolidone 1.5%, glycerine 1.2%, silicone compound 0.3%, agriculture breast 500#5%, water add to 100%, mix and make 45% glyoxalin ZJ0712 suspension emulsion.
Example 17 45% glyoxalin pyraclostrobin wetting powders
Glyoxalin 15%, pyraclostrobin 30%, polyoxyethylene carboxylate 6%, silkworm excrement 5%, kaolin add to 100%, and mixture carries out air-flow crushing, make 45% glyoxalin pyraclostrobin wetting powder.
Example 18 70% glyoxalin pyraclostrobin wetting powders
Glyoxalin 10%, pyraclostrobin 60%, alkyl benzene sulfonate calcium salt 8%, Nekal BX 6%, diatomite add to 100%, and mixture carries out air-flow crushing, make 70% glyoxalin pyraclostrobin wetting powder.
Example 19 42% glyoxalin pyraclostrobin water dispersible granules
Glyoxalin 20%, pyraclostrobin 22%, alkylphenol-polyethenoxy are phonetic 7%, lauryl sodium sulfate 5%, bentonite add to 100%, mix and make 42% glyoxalin pyraclostrobin water dispersible granules.
Example 20 55% glyoxalin pyraclostrobin water dispersible granules
Glyoxalin 15%, pyraclostrobin 40%, polycarboxylate 6%, wetting and penetrating agent F4%, urea 1.3%, attapulgite add to 100%, mix and make 55% glyoxalin pyraclostrobin water dispersible granules.
Example 21 10% glyoxalin pyraclostrobin suspending agents
Glyoxalin 5%, pyraclostrobin 5%, alkyl benzene sulfonate calcium salt 8%, neopelex 5%, C
8～10Aliphatic alcohols 0.5%, methylcellulose 1.6%, glycerine 1.8%, deionized water add to 100%, mix and make 10% glyoxalin pyraclostrobin suspending agent.
Example 22 40% glyoxalin pyraclostrobin suspending agents
Glyoxalin 8%, pyraclostrobin 32%, the phonetic formaldehyde condensation products sulphate 7% of alkylphenol-polyethenoxy, silkworm excrement 5%, C
10～20Saturated fat acids 0.7%, xanthans 1.3%, ethylene glycol 1.7%, deionized water add to 100%, mix and make 40% glyoxalin pyraclostrobin suspending agent.
Example 23 30% glyoxalin pyraclostrobin suspension emulsions
Glyoxalin 20%, pyraclostrobin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, soapberry powder 4%, methylcellulose 1.5%, ethylene glycol 1.4%, silicone compound 0.6%, agriculture breast 1600#6%, water add to 100%, mix and make 30% glyoxalin pyraclostrobin suspension emulsion.
Example 24 36% glyoxalin pyraclostrobin suspension emulsions
Glyoxalin 12%, pyraclostrobin 24%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, wetting and penetrating agent F6%, xanthans 1.7%, propane diols 1.6%, C
10～20Saturated fat acids 0.4%, AEO series 5%, water add to 100%, mix and make 36% glyoxalin pyraclostrobin suspension emulsion.
Example 25 55% glyoxalin Enestroburin wetting powders
Glyoxalin 10%, Enestroburin 45%, lignosulfonates 8%, Nekal BX 6%, bentonite add to 100%, and mixture carries out air-flow crushing, make 55% glyoxalin Enestroburin wetting powder.
Example 26 70% glyoxalin Enestroburin wetting powders
Glyoxalin 20%, Enestroburin 50%, polyoxyethylene carboxylate 6%, spaonin powder 5%, starch add to 100%, and mixture carries out air-flow crushing, make 70% glyoxalin Enestroburin wetting powder.
Example 27 50% glyoxalin Enestroburin water dispersible granules
Glyoxalin 10%, Enestroburin 40%, octylphenol polyethylene oxyethylene group ether sulfate 5%, silkworm excrement 4%, aluminium chloride 1.5%, diatomite add to 100%, mix and make 50% glyoxalin Enestroburin water dispersible granules.
Example 28 65% glyoxalin Enestroburin water dispersible granules
Glyoxalin 30%, Enestroburin 35%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, wetting and penetrating agent F5%, bentonite add to 100%, mix and make 65% glyoxalin Enestroburin water dispersible granules.
Example 29 15% glyoxalin Enestroburin suspending agents
Glyoxalin 10%, Enestroburin 5%, aliphatic amine polyoxyethylene are phonetic 7%, soapberry powder 5%, silicone oil 0.4%, sodium phosphate trimer 1.2%, polyethylene glycol 1.7%, deionized water add to 100%, mix and make 15% glyoxalin Enestroburin suspending agent.
Example 30 45% glyoxalin Enestroburin suspending agents
Glyoxalin 15%, Enestroburin 30%, alkyl benzene sulfonate calcium salt 6%, lauryl sodium sulfate 4%, C
8～10Aliphatic alcohols 0.3%, xanthans 1.4%, glycerine 1.6%, deionized water add to 100%, mix and make 45% glyoxalin Enestroburin suspending agent.
Example 31 16% glyoxalin Enestroburin suspension emulsions
Glyoxalin 8%, Enestroburin 8%, naphthalene sulfonic acid-formaldehyde condensation product 7%, wetting and penetrating agent F5%, crospolyvinylpyrrolidone 1.3%, ethylene glycol 1.8%, C
10～20Saturated fat acids 0.5%, Nongru-700 #5%, water add to 100%, mix and make 16% glyoxalin Enestroburin suspension emulsion.
Example 32 42% glyoxalin Enestroburin suspension emulsions
Glyoxalin 14%, Enestroburin 28%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, spaonin powder 4%, polyvinylpyrrolidone 1.7%, propane diols 1.2%, silicone compound 0.6%, agriculture breast 1600#6%, water add to 100%, mix and make 42% glyoxalin Enestroburin suspension emulsion.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect, on this basis, then carry out field trial.
Glyoxalin and active component B(B are selected from a kind of of kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established respectively 5 dosage by active constituent content and is processed, and established the clear water contrast.With reference to " farm-chemical indoor determination test rule bactericide ", carry out, adopt the mycelial growth rate method to measure the virulence of medicament to the crop germ.After 72h, with the right-angled intersection method, measure colony diameter, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into to probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50Value.According to the Wadley method, calculate the different proportioning synergy ratio (SR) of two medicaments simultaneously, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component glyoxalin and B(kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin) shared ratio in combination;
A is glyoxalin;
B is a kind of in kresoxim-methyl, ZJ0712, pyraclostrobin, Enestroburin.
Implementation of an application example diimine azoles and kresoxim-methyl are composite to the alternaria leaf spot of apple Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of kresoxim-methyl and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 1 glyoxalin, kresoxim-methyl and the composite analysis of results table of toxicity test to alternaria leaf spot of apple thereof
As shown in Table 1, glyoxalin, the kresoxim-methyl EC to alternaria leaf spot of apple
50Be respectively 0.68mg/L and 1.47mg/L.Glyoxalin and kresoxim-methyl proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and kresoxim-methyl are mixed and all show synergistic effect in 50 ︰ 1 to 1 ︰ 60 scopes, especially when the two proportioning during at 2:1 to 1:8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and kresoxim-methyl weight ratio are 1 ︰ 2 wherein, synergistic effect is the most obvious.
Implementation of an application example three glyoxalins and ZJ0712 are composite to the powdery mildew of cucumber Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of ZJ0712 and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 2 glyoxalin, ZJ0712 and the composite analysis of results table of toxicity test to powdery mildew of cucumber thereof
As shown in Table 2, glyoxalin, the ZJ0712 EC to powdery mildew of cucumber
50Be respectively 0.76mg/L and 0.34mg/L.Glyoxalin and ZJ0712 proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and ZJ0712 are mixed and all show synergistic effect in 50 ︰ 1 to 1 ︰ 60 scopes, especially when the two proportioning during at 8:1 to 1:2, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and ZJ0712 weight ratio are 2 ︰ 1 wherein, synergistic effect is the most obvious.
Implementation of an application example four
Glyoxalin and pyraclostrobin are composite to the banana freckle Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of pyraclostrobin and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 3 glyoxalin, pyraclostrobin and the composite analysis of results table of toxicity test to banana freckle thereof
As shown in Table 3, glyoxalin, the pyraclostrobin EC to banana freckle
50Be respectively 0.71mg/L and 1.58mg/L.Glyoxalin and pyraclostrobin proportioning are when 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and pyraclostrobin are mixed and all show synergistic effect in 50 ︰ 1 to 1 ︰ 60 scopes, especially when the two proportioning during at 2:1 to 1:8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and pyraclostrobin weight ratio are 1 ︰ 2 wherein, synergistic effect is the most obvious.
Implementation of an application example five:
Glyoxalin and Enestroburin are composite to the pear scab Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of Enestroburin and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 4 glyoxalin, Enestroburin and the composite analysis of results table of toxicity test to pear scab thereof
As shown in Table 4, glyoxalin, the Enestroburin EC to pear scab
50Be respectively 0.65mg/L and 1.42mg/L.Glyoxalin and Enestroburin are than when the 50:1 to 1:60, synergy ratio SR is all greater than 1.5, illustrate that glyoxalin and Enestroburin are mixed and all show synergistic effect in 2 ︰ 1 to 1 ︰ 8 scopes, synergy ratio SR maximum when glyoxalin and Enestroburin weight ratio are 1 ︰ 2 wherein, synergistic effect is the most obvious.
Application Example six glyoxalins and kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Dali County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 50% water dispersion granules agent of Kresoxim (commercial).
Investigation alternaria leaf spot of apple disease index before medicine, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, for the second time 7 days, 14 days investigation disease indexs calculate preventive effect after dispenser.Experimental result is as follows:
Table 5 glyoxalin, kresoxim-methyl and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 5, after glyoxalin and kresoxim-methyl are composite, can effectively prevent and treat alternaria leaf spot of apple, control efficiency all is better than the preventive effect of single dose.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven glyoxalins and ZJ0712 and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in the Qingdao of Shandong province suburb, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 10% ZJ0712 suspending agent (commercial).
The investigation powdery mildew of cucumber state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.After dispenser, investigated respectively disease index and calculated preventive effect in 7 days, 14 days for the second time.Experimental result is as follows:
Table 6 glyoxalin, ZJ0712 and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 6, after glyoxalin and ZJ0712 are composite, can effectively prevent and treat powdery mildew of cucumber, control efficiency all is better than the preventive effect of single dose.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight glyoxalins and pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
This experimental establishment is in Longan County, Guangxi province Nanning City, and test medicine is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 250 grams per liter pyraclostrobin missible oil (commercial).
The investigation banana freckle state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 10 days.After dispenser, investigated respectively disease index and calculated preventive effect in 7 days, 14 days for the second time.Experimental result is as follows:
Table 7 glyoxalin, pyraclostrobin and the composite control banana freckle test of pesticide effectiveness thereof
As can be seen from Table 7, after glyoxalin and pyraclostrobin are composite, can effectively prevent and treat banana freckle, control efficiency all is better than the preventive effect of single dose.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine glyoxalins and Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Pucheng County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 25% Enestroburin missible oil (commercial).
Investigation pear scab disease index before medicine, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, for the second time 7 days, 14 days investigation disease indexs calculate preventive effect after dispenser.Experimental result is as follows:
Table 8 glyoxalin, Enestroburin and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 8, after glyoxalin and Enestroburin are composite, can effectively prevent and treat pear scab, control efficiency all is better than the preventive effect of single dose.In the test scope of medication, the target crop is had no adverse effects.
Claims (5)
1. bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds, comprise effective active component, auxiliary agent and filler, it is characterized in that: the effective active composition is comprised of glyoxalin and ZJ0712, and glyoxalin and ZJ0712 percentage by weight are 1～50% ︰ 1～60%.
2. a kind of bactericidal composition that contains glyoxalin and methoxy acrylic ester compounds according to claim 1, it is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 2～40% ︰ 2～50%.
3. the bactericidal composition that contains glyoxalin according to claim 2, it is characterized in that: the percentage by weight of glyoxalin and ZJ0712 is 5～30% ︰ 5～20%.
4. the bactericidal composition that contains glyoxalin according to claim 1, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent or suspension emulsion.
5. the bactericidal composition that contains glyoxalin according to claim 1 is mainly used in preventing and treating paddy rice, vegetables, fruit tree multiple diseases.
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| CN101167455A (en) * | 2007-12-06 | 2008-04-30 | 张少武 | Imibenconazole water dispersible granule and preparation method thereof |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN101715771A (en) * | 2009-11-30 | 2010-06-02 | 福建新农大正生物工程有限公司 | Sterilizing composition containing imibenconazole |
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| CN101167455A (en) * | 2007-12-06 | 2008-04-30 | 张少武 | Imibenconazole water dispersible granule and preparation method thereof |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
| CN101715771A (en) * | 2009-11-30 | 2010-06-02 | 福建新农大正生物工程有限公司 | Sterilizing composition containing imibenconazole |
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