CN102016009B - 膜 - Google Patents

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Publication number
CN102016009B
CN102016009B CN200980113395.3A CN200980113395A CN102016009B CN 102016009 B CN102016009 B CN 102016009B CN 200980113395 A CN200980113395 A CN 200980113395A CN 102016009 B CN102016009 B CN 102016009B
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CN
China
Prior art keywords
membrane
cells
film
hesc
rpe
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CN200980113395.3A
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English (en)
Chinese (zh)
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CN102016009A (zh
Inventor
彼得·科菲
林登·Da·克鲁兹
凯伦·奇塔姆
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UCL Business Ltd
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UCL Business Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN200980113395.3A 2008-04-14 2009-04-08 膜 Active CN102016009B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0806746.4 2008-04-14
GBGB0806746.4A GB0806746D0 (en) 2008-04-14 2008-04-14 Membrane
PCT/GB2009/000917 WO2009127809A1 (en) 2008-04-14 2009-04-08 Membrane

Publications (2)

Publication Number Publication Date
CN102016009A CN102016009A (zh) 2011-04-13
CN102016009B true CN102016009B (zh) 2015-05-20

Family

ID=39433610

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980113395.3A Active CN102016009B (zh) 2008-04-14 2009-04-08 膜

Country Status (19)

Country Link
US (2) US8642072B2 (enExample)
EP (1) EP2265711B1 (enExample)
JP (1) JP5552478B2 (enExample)
KR (2) KR101317094B1 (enExample)
CN (1) CN102016009B (enExample)
AU (1) AU2009237462B2 (enExample)
BR (1) BRPI0910936A2 (enExample)
CA (1) CA2720264C (enExample)
CO (1) CO6311115A2 (enExample)
DK (1) DK2265711T3 (enExample)
ES (1) ES2665284T3 (enExample)
GB (1) GB0806746D0 (enExample)
IL (1) IL208745A (enExample)
MX (1) MX2010011232A (enExample)
MY (1) MY159049A (enExample)
NZ (1) NZ587753A (enExample)
RU (1) RU2530169C2 (enExample)
WO (1) WO2009127809A1 (enExample)
ZA (1) ZA201006326B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110112101A1 (en) * 2009-03-05 2011-05-12 Sanofi-Aventis Treatment for ocular-related disorders
JP5867926B2 (ja) * 2010-05-10 2016-02-24 公立大学法人名古屋市立大学 細胞シート作製方法
EP4245370A3 (en) 2010-07-12 2023-11-29 University of Southern California Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same
CN103459593A (zh) * 2011-02-25 2013-12-18 独立行政法人理化学研究所 视网膜色素上皮细胞片层的生产方法
US8877489B2 (en) 2011-12-05 2014-11-04 California Institute Of Technology Ultrathin parylene-C semipermeable membranes for biomedical applications
US10478206B2 (en) 2011-04-29 2019-11-19 University Of Southern California Instruments and methods for the implantation of cell-seeded substrates
WO2012177968A1 (en) * 2011-06-22 2012-12-27 The Schepens Eye Research Institute, Inc. A scaffold for subretinal cell transplantation and drug delivery
US9763777B2 (en) 2011-07-11 2017-09-19 Ear Science Institute Australia Device for ear drum repair
CN103007355B (zh) * 2011-09-20 2014-08-13 同济大学 一种水凝胶-纳米纤维膜及其制备方法和用途
CA2792081C (en) * 2011-10-11 2020-10-27 Bond University Ltd Layered compositions comprising 3d nanofibre webbing for tissue repair
CA2855941A1 (en) 2011-11-14 2013-05-23 Advanced Cell Technology, Inc. Pharmaceutical preparations of human rpe cells and uses thereof
US9248013B2 (en) 2011-12-05 2016-02-02 California Institute Of Technology 3-Dimensional parylene scaffold cage
US20130330825A1 (en) * 2012-06-07 2013-12-12 City Of Hope Attachment substrates for directed differentiation of human embryonic stem cells in culture
US11033586B2 (en) 2012-08-24 2021-06-15 Riken Method for producing retinal pigment epithelial cell sheet
RU2518972C1 (ru) * 2012-12-24 2014-06-10 Общество с ограниченной ответственностью "НАНО КАСКАД" Трековая мембрана для фильтрации крови
EP3080248A1 (en) 2013-12-11 2016-10-19 Pfizer Limited Method for producing retinal pigment epithelial cells
CN105013010B (zh) * 2015-07-07 2018-01-12 中山大学中山眼科中心 一种辅助iPS‑RPE移植的层粘连蛋白膜
CN105597145A (zh) * 2016-02-22 2016-05-25 中山大学中山眼科中心 一种视网膜细胞支架生物手术粘合剂及其制备方法
CN109790508A (zh) * 2016-06-28 2019-05-21 国立研究开发法人农业·食品产业技术综合研究机构 细胞封入用设备及其用途
WO2020047380A1 (en) 2018-08-31 2020-03-05 Wisconsin Alumni Research Foundation Generating arterial endothelial cell-seeded vascular grafts
TWI820330B (zh) * 2019-04-26 2023-11-01 國立研究開發法人理化學研究所 包含神經視網膜與視網膜色素上皮細胞與水凝膠之複合體及其製造方法
RU2704094C1 (ru) * 2019-05-16 2019-10-23 федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ трансплантации ретинального пигментного эпителия в форме многоклеточных 3D сфероидов в эксперименте
JP2021141877A (ja) * 2020-03-13 2021-09-24 大日本印刷株式会社 細胞培養基材、細胞付細胞培養基材、細胞培養容器、細胞付細胞培養容器、上皮細胞シート及びその製造方法、被験物質の評価方法並びに評価キット
JP7676135B2 (ja) * 2020-12-14 2025-05-14 日本バイリーン株式会社 細胞培養担体

Citations (1)

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CN1739813A (zh) * 2005-09-15 2006-03-01 上海赐人合元企业发展有限公司 组织工程表皮替代物及其制备方法

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Patent Citations (1)

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CN1739813A (zh) * 2005-09-15 2006-03-01 上海赐人合元企业发展有限公司 组织工程表皮替代物及其制备方法

Non-Patent Citations (2)

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Transplantation of the RPE in AMD;Susanne Binder et al.;《Progress in Retinal and Eye Research》;20071231;第26卷;516–554 *

Also Published As

Publication number Publication date
GB0806746D0 (en) 2008-05-14
EP2265711A1 (en) 2010-12-29
IL208745A0 (en) 2010-12-30
DK2265711T3 (en) 2018-04-30
WO2009127809A1 (en) 2009-10-22
MX2010011232A (es) 2011-02-23
KR101317094B1 (ko) 2013-10-16
KR20100128329A (ko) 2010-12-07
ZA201006326B (en) 2011-09-28
BRPI0910936A2 (pt) 2015-10-06
US8889179B2 (en) 2014-11-18
CN102016009A (zh) 2011-04-13
ES2665284T3 (es) 2018-04-25
IL208745A (en) 2015-04-30
MY159049A (en) 2016-12-15
JP5552478B2 (ja) 2014-07-16
CO6311115A2 (es) 2011-08-22
US8642072B2 (en) 2014-02-04
JP2011517696A (ja) 2011-06-16
US20140127282A1 (en) 2014-05-08
RU2010144399A (ru) 2012-05-20
EP2265711B1 (en) 2018-03-07
AU2009237462A1 (en) 2009-10-22
KR20130065737A (ko) 2013-06-19
RU2530169C2 (ru) 2014-10-10
CA2720264A1 (en) 2009-10-22
AU2009237462B2 (en) 2012-12-20
NZ587753A (en) 2012-07-27
CA2720264C (en) 2016-09-27
US20110236464A1 (en) 2011-09-29

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