CN101977630B - 眼药组合物 - Google Patents

眼药组合物 Download PDF

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Publication number
CN101977630B
CN101977630B CN2009801095970A CN200980109597A CN101977630B CN 101977630 B CN101977630 B CN 101977630B CN 2009801095970 A CN2009801095970 A CN 2009801095970A CN 200980109597 A CN200980109597 A CN 200980109597A CN 101977630 B CN101977630 B CN 101977630B
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CN
China
Prior art keywords
composition
viscosity
polyvinylpyrrolidone
ophthalmic
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009801095970A
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English (en)
Chinese (zh)
Other versions
CN101977630A (zh
Inventor
阿林达曼·霍尔德
埃杰伊·杰伊辛·库帕德
苏巴斯·巴拉罗姆·鲍米克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Ltd
Original Assignee
Sun Pharmaceutical Advanced Research Centre Ltd
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Publication date
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Publication of CN101977630A publication Critical patent/CN101977630A/zh
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Publication of CN101977630B publication Critical patent/CN101977630B/zh
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2009801095970A 2008-03-07 2009-03-09 眼药组合物 Expired - Fee Related CN101977630B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN477MU2008 2008-03-07
IN477/MUM/2008 2008-03-07
PCT/IN2009/000162 WO2009110009A2 (en) 2008-03-07 2009-03-09 Opthalmic composition

Publications (2)

Publication Number Publication Date
CN101977630A CN101977630A (zh) 2011-02-16
CN101977630B true CN101977630B (zh) 2012-11-21

Family

ID=41056432

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801095970A Expired - Fee Related CN101977630B (zh) 2008-03-07 2009-03-09 眼药组合物

Country Status (9)

Country Link
US (1) US20110003816A1 (https=)
EP (1) EP2249871A4 (https=)
JP (1) JP2011513393A (https=)
KR (1) KR20100133980A (https=)
CN (1) CN101977630B (https=)
BR (1) BRPI0909797A2 (https=)
CA (1) CA2717825A1 (https=)
MX (1) MX2010009857A (https=)
WO (1) WO2009110009A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201301332A1 (ru) * 2011-05-27 2014-06-30 Рациофарм Гмбх ОФТАЛЬМОЛОГИЧЕСКИЙ ПРЕПАРАТ, СОДЕРЖАЩИЙ АНАЛОГ PGF2α
JP6260230B2 (ja) * 2013-11-28 2018-01-17 ライオン株式会社 眼科用組成物
EP2979689A1 (en) * 2014-07-29 2016-02-03 Sygene Technologies Composition for an eye drop and delivery system therefor
CN106619573B (zh) * 2016-12-27 2019-09-20 广州中大南沙科技创新产业园有限公司 马来酸噻吗洛尔立方液晶纳米粒滴眼液及其制备方法
DE102017103346A1 (de) * 2017-02-17 2018-08-23 Lts Lohmann Therapie-Systeme Ag Strukturierte orodispergierbare Filme
CN117137866A (zh) * 2018-02-28 2023-12-01 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物
WO2020050423A1 (ja) 2018-09-07 2020-03-12 株式会社ファルネックス 非ラメラ液晶形成脂質を含む外用剤
CN115737654B (zh) * 2021-09-03 2025-11-21 成都瑞沐生物医药科技有限公司 一种滴眼给药预防和/或治疗白内障的眼用制剂
JPWO2023054669A1 (https=) * 2021-09-30 2023-04-06

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
US4474752A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
JP2594486B2 (ja) * 1991-01-15 1997-03-26 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物
JP2719049B2 (ja) * 1991-01-28 1998-02-25 日本碍子株式会社 ランタンクロマイト膜の製造方法及び固体電解質型燃料電池用インターコネクターの製造方法
SE512871C2 (sv) * 1992-08-20 2000-05-29 Santen Oy Oftalmologisk beredning innehållande pilokarpin och ytterligare medel för behandling av okular hypertension
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
US6335335B2 (en) * 1997-11-05 2002-01-01 Senju Pharmaceutical Co., Ltd. Prolonged-action eye drop
US6174524B1 (en) * 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6962691B1 (en) * 1999-05-20 2005-11-08 U & I Pharmaceuticals Ltd. Topical spray compositions
US7081482B2 (en) * 1999-11-30 2006-07-25 Alcon, Inc. Use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
AU2225701A (en) * 1999-12-27 2001-07-09 Santen Pharmaceutical Co. Ltd. System for stabilizing lacrimal fluid layer
EP1627637A1 (en) * 2003-05-23 2006-02-22 Santen Pharmaceutical Co., Ltd. Ophthalmic solution containing quinolone antimicrobial compound
US7063862B2 (en) * 2003-06-03 2006-06-20 Biokey, Inc. Pharmaceutical composition and method for treating
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
CA2839847C (en) * 2003-06-13 2016-03-15 Masood A. Chowhan Ophthalmic compositions containing a synergistic combination of two polymers
US6960300B2 (en) * 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications
WO2007002669A1 (en) * 2005-06-28 2007-01-04 Bausch & Lomb Incorporated In-eye method of cleaning and/or disinfecting silicone hydrogel contact lenses

Also Published As

Publication number Publication date
MX2010009857A (es) 2010-12-07
KR20100133980A (ko) 2010-12-22
BRPI0909797A2 (pt) 2017-08-22
WO2009110009A2 (en) 2009-09-11
EP2249871A4 (en) 2011-03-16
CN101977630A (zh) 2011-02-16
JP2011513393A (ja) 2011-04-28
EP2249871A2 (en) 2010-11-17
WO2009110009A3 (en) 2009-12-23
US20110003816A1 (en) 2011-01-06
CA2717825A1 (en) 2009-09-11

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Granted publication date: 20121121

Termination date: 20140309