CN101972441A

CN101972441A - Medicament for treating cough and asthma and preparation method thereof

Info

Publication number: CN101972441A
Application number: CN 201010516353
Authority: CN
Inventors: 王蔚
Original assignee: Individual
Current assignee: Huang Jinyan
Priority date: 2010-10-11
Filing date: 2010-10-11
Publication date: 2011-02-16
Anticipated expiration: 2030-10-11
Also published as: CN101972441B

Abstract

The invention discloses a medicament for treating cough and asthma and a preparation method thereof. The medicament consists of the following components in part by weight: 15 to 20 parts of platycodon root, 15 to 20 parts of sessile stemona root, 20 to 25 parts of whiteflower hogfennel root, 15 to 20 parts of perilla seed, 20 to 25 parts of roasted ephedra herb, 20 to 25 parts of baical skullcap root, 15 to 20 parts of immature bitter orange, 10 to 15 parts of raw liquoric root, 15 to 20 parts of prepared common monkshood daughter root, 20 to 25 parts of prepared rehmannia root, 15 to 20 parts of common macrocarpium fruit, 20 to 25 parts of epimedium herb, 20 to 25 parts of medicinal indianmulberry root and 3 to 10 parts of Chinese yam rhizome. The preparation method comprises the following steps of: drying the Chinese yam rhizome and the epimedium herb, grinding into fine powder and sieving with a screen of 100 meshes for later use; weighing and mixing the other medicaments in the prescription, soaking in water, decocting for two times, combining two-time filtrate, concentrating to form liquor with the relative density of 1.05 to 1.10, refrigerating at the temperature of 10 DEG C for 24 hours, and concentrating supernatant until heat test specific gravity is 1.35 to 1.40; and adding the fine powder of the Chinese yam rhizome and the epimedium herb, uniformly stirring, performing vacuum drying, grinding coarse powder, sieving with a screen of 14 meshes, wetting the fine powder, pelleting, sieving with the screen of 14 meshes, drying, mixing and granulating, and tabletting or pelleting or filling into capsules or preparing pills.

Description

A kind of medicine for the treatment of cough and asthma and preparation method thereof

Affiliated technical field

The invention belongs to the Chinese medicine preparation technical field, relating to a kind of is the medicine and preparation method thereof of raw material treatment cough and asthma with the Chinese herbal medicine.

Background technology

Cough and asthma are a kind of commonly encountered diseases and frequently-occurring disease, and these disease serious harm people's is healthy, and for a long time, doctor trained in Western medicine adopts the method for anti-inflammation to treat this disease always.But some patient uses antibiotic therapy one month also ineffective continuously, makes patient very painful, and the doctor has a headache very much.Therefore, according to the tcm treatment according to syndrome differentiation theory, the Chinese patent medicine of exploitation treatment cough and asthma just has crucial meaning.

Summary of the invention:

The purpose of this invention is to provide a kind of Chinese medicine for the treatment of cough and asthma and preparation method thereof.

In order to achieve the above object, a kind of medicine for the treatment of cough and asthma of the present invention and preparation method thereof, the weight proportion of its medicine is: Radix Platycodonis 15～20, the Radix Stemonae 15～20, Radix Peucedani 20～25, Fructus Perillae 15～20, Herba Ephedrae (processed) 20～25, Radix Scutellariae 20～25, Fructus Aurantii Immaturus 15～20, Radix Glycyrrhizae 10～15, Radix Aconiti Lateralis Preparata 15～20, Radix Rehmanniae Preparata 20～25, Fructus Corni 15～20, Herba Epimedii 20～25, Radix Morindae Officinalis 20～25, Rhizoma dioscoreae 5～10.The dosage form of medicine is tablet or capsule or pill or granule.Suggestion instructions about how to take medicine and consumption: oral, 3 times/day, 8 gram/time (tablet or capsule or pill or granules) divide early, middle and late clothes.

The manufacture method of medicine of the present invention is: with Rhizoma dioscoreae and Herba Epimedii drying; wearing into fine powder, to cross 100 mesh sieves standby; the water logging that adds 5～8 times of drug weight after then all the other the medicine weighings in the above-mentioned prescription being mixed was steeped 2 hours; decocting secondary (decocts 1.5 hours after-filtration for the first time and goes out medicinal liquid; the decocting that adds for the second time 4～5 times of drug weight in medicinal residues boils 1 hour after-filtration and goes out medicinal liquid); merge 2 times filtrate; being concentrated into relative density is 1.05～1.10; 10 ℃ of following cold preservations, getting its supernatant reconcentration to heat survey proportion after 24 hours is 1.35～1.40, adds Rhizoma dioscoreae and Herba Epimedii fine powder; stir evenly; vacuum drying, the mill coarse powder is crossed 14 mesh sieves; granulate after the fine powder moistening; cross 14 mesh sieves, drying is mixed behind the granulate tabletting or is made granule or make capsule or make pill.

The present invention is through 400 routine clinical trials, random packet, double blinding dual analog case shows: with Drug therapy 200 examples of the present invention, be 85.1% to the cure-remarkable-effectiveness rate of cough and asthma, total effective rate is 98.2%, following up a case by regular visits to 3 months cure-remarkable-effectiveness rates is 88.3%, and total effective rate is 98.5%, and matched group is treated 200 examples with relieving cough and relieving asthma cream, cure-remarkable-effectiveness rate to cough and asthma is 70.2%, total effective rate is 81.5%, and following up a case by regular visits to 3 months cure-remarkable-effectiveness rates is 65.7%, and total effective rate is 84.6%.Treatment group and matched group clinical efficacy, follow up a case by regular visits to the comparison of curative effect, medicine of the present invention obviously is better than relieving cough and relieving asthma cream matched group (P＜0.01).

The invention has the beneficial effects as follows that this medicine has that lung moistening is induced sweat, the effect of relieving cough and resolving phlegm, antiinflammatory Zhichuan, strengthening spleen, tonifying kidney, by strengthening spleen, tonifying kidney, relieving cough and resolving phlegm, reaches the therapeutical effect of relieving cough and asthma.

Embodiment one:

1, to cross 100 mesh sieves standby with wearing into fine powder after the Rhizoma dioscoreae 10 of weight proportion and Herba Epimedii 20 dryings.

2, Radix Platycodonis 15 with weight proportion, the Radix Stemonae 15, Radix Peucedani 20, Fructus Perillae 15, Herba Ephedrae (processed) 20, Radix Scutellariae 25, Fructus Aurantii Immaturus 20, Radix Glycyrrhizae 10, Radix Aconiti Lateralis Preparata 15, Radix Rehmanniae Preparata 25, Fructus Corni 20, Radix Morindae Officinalis 25 medical materials add the water logging of 8 times of drug weight and steeped 2 hours, decocting secondary (decocts 1.5 hours after-filtration for the first time and goes out medicinal liquid, the decocting that adds for the second time 4 times of drug weight in medicinal residues boils 1 hour after-filtration and goes out medicinal liquid), merge 2 times filtrate, being concentrated into relative density is 1.05,10 ℃ of following cold preservations, getting supernatant reconcentration to heat survey proportion after 24 hours is 1.40, add Rhizoma dioscoreae and Herba Epimedii fine powder, stir evenly, vacuum drying, the mill coarse powder is crossed 14 mesh sieves, granulate after the fine powder moistening, cross 14 mesh sieves, drying, tabletting behind the mixing granulate.

Embodiment two:

1, to cross 100 mesh sieves standby with wearing into fine powder after the Rhizoma dioscoreae 8 of weight proportion and Herba Epimedii 25 dryings.

2, Radix Platycodonis 20 with weight proportion, the Radix Stemonae 20, Radix Peucedani 20, Fructus Perillae 15, Herba Ephedrae (processed) 20, Radix Scutellariae 25, Fructus Aurantii Immaturus 15, Radix Glycyrrhizae 15, Radix Aconiti Lateralis Preparata 15, Radix Rehmanniae Preparata 205, Fructus Corni 15, Radix Morindae Officinalis 20 medical materials add the water logging of 8 times of drug weight and steeped 2 hours, decocting secondary (decocts 1.5 hours after-filtration for the first time and goes out medicinal liquid, the decocting that adds for the second time 4 times of drug weight in medicinal residues boils 1 hour after-filtration and goes out medicinal liquid), merge 2 times filtrate, being concentrated into relative density is 1.05,10 ℃ of following cold preservations, getting supernatant reconcentration to heat survey proportion after 24 hours is 1.40, add Rhizoma dioscoreae and Herba Epimedii fine powder, stir evenly, vacuum drying, the mill coarse powder is crossed 14 mesh sieves, granulate after the fine powder moistening, cross 14 mesh sieves, drying pours into capsule behind the mixing granulate.

Claims

1. a medicine for the treatment of cough and asthma is characterized in that this drug weight proportioning consists of: Radix Platycodonis 15～20, the Radix Stemonae 15～20, Radix Peucedani 20～25, Fructus Perillae 15～20, Herba Ephedrae (processed) 20～25, Radix Scutellariae 20～25, Fructus Aurantii Immaturus 15～20, Radix Glycyrrhizae 10～15, Radix Aconiti Lateralis Preparata 15～20, Radix Rehmanniae Preparata 20～25, Fructus Corni 15～20, Herba Epimedii 20～25, Radix Morindae Officinalis 20～25, Rhizoma dioscoreae 3～10.

2. a kind of medicine for the treatment of cough and asthma according to claim 1; the manufacture method that it is characterized in that this medicine is: with Rhizoma dioscoreae and Herba Epimedii drying; wear into fine powder; it is standby to cross 100 mesh sieves; the water logging bubble 2 hours that adds 5～8 times of drug weight after then all the other the medicine weighings in the above-mentioned prescription being mixed, decocting 1.5 hours after-filtration, to go out medicinal liquid standby, adds the water of 4～5 times of drug weight again in the medicine residue; decoct 1 hour after-filtration and go out medicinal liquid; merge 2 times filtrate, it is concentrated into relative density is 1.05～1.10, then 10 ℃ of following cold preservations 24 hours; getting supernatant reconcentration to heat survey proportion is 1.35～1.40; add Rhizoma dioscoreae and Herba Epimedii fine powder, stir evenly vacuum drying; the mill coarse powder; cross 14 mesh sieves, granulate after the fine powder moistening, cross 14 mesh sieves; drying is mixed behind the granulate tabletting or granulation or is poured into capsule or make pill.

3. a kind of medicine for the treatment of cough and asthma according to claim 1, the dosage form that it is characterized in that this medicine is tablet or capsule or pill or granule.