CN101912577B - Medicament for treating rheumatism and rheumatoid disease and preparation process - Google Patents
Medicament for treating rheumatism and rheumatoid disease and preparation process Download PDFInfo
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Abstract
The invention discloses a medicament for treating rheumatism and rheumatoid disease, which is prepared from the following raw materials: himalayan teasel root, Chinese angelica, incised notopterygium rhizome, pubescent angelica root, Chinese flowering quince, cassia twig, quilled cinnamon bark, rehmanniae vaporata, Ningxia medlar, swordlike atractylodes rhizome, zedoary, szechuan lovage rhizome, tuber fleeceflower root, poria, szechwon tangshen root, adenophora, panax ginseng, rhizoma corydalis, nutgrass galingale rhizome, clematis root, akebia stem, large-headed atractylodes rhizome, eucommia bark, cibotium barometz, India madder root, gambir plant, root of largeleaf gentian, psoralea fruit, south dodder seed, glossy privet fruit, common clubmoss herb, medicinal indianmulberry root, cistanche, songaria cynomorium herb, scorpion and leech. The medicament is prepared by taking natural traditional Chinese medicines as raw materials and can be made into preparations for clinic use such as tablets, capsules, granules, vina or pills by a method of the conventional preparation of a Chinese medicinal preparation. In the medicament, the capsules are preferable, and the medicament has the advantages of obvious and stable curative effect, no toxic nor side effect, convenient administration, simple and convenient preparation and the like.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of rheumatism, rheumatoid disease, particularly a kind of is the treatment rheumatism made of raw material, the medicine and the preparation technology of rheumatoid disease with the natural Chinese medicine.
Background technology
Rheumatism, rheumatoid are the osteoarticular commonly encountered diseases of mankind nowadays, frequently-occurring disease, and the international especially difficult disease of rheumatoid is a kind of chronic noninfective inflammation of joint part.Its clinical manifestation symptom mostly is: a plurality of positions of whole body arthralgia, deformity, corresponding joint dysfunction etc., modern medicine does not still have special effect medicine therapeutic, how to add the anti-inflammatory analgesic chemotherapy based on adrenocortical hormone, but the patient is difficult to bear for a long time the infringement to health of hormone and chemicals, and the utmost point is ready to accept to have the Chinese medicine of stable curative effect.
The existing medicine that is used for the treatment of rheumatism, rheumatoid disease mainly contains meticortelone and dexamethasone, class are liked health sheet, indometacin tablets, Radix Tripterygii Wilfordii tablet lamp bitterly on the market, but these medicines all exist curative effect remarkable inadequately to some extent, and obvious toxic and side effects is arranged.Take defectives such as having dependency, addiction for a long time.
Summary of the invention
Purpose of the present invention just is to overcome the deficiencies in the prior art, and a kind of treatment rheumatism made from raw material of Chinese medicine, the medicine and the preparation technology of rheumatoid disease are provided, and this curative effect of medication is significantly stable, have no side effect, and taking convenience, simple for production.
The objective of the invention is to be achieved through the following technical solutions: a kind of medicine for the treatment of rheumatism, rheumatoid disease, it is the medicament of being made by the following weight proportion raw material:
Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35,15-35 rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12.
Optimum, a kind of medicine for the treatment of rheumatism, rheumatoid disease, wherein the weight proportion of each raw material is: Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10.
The medicine of treatment rheumatism of the present invention, rheumatoid disease can adopt the conventional formulation method of Chinese medicine preparation to be prepared into any suitable clinical preparation, for example can be tablet, capsule, granule, pill, medicated wine etc., preferably capsule.
The preparation technology of the medicine of treatment rheumatism, rheumatoid disease, its step is as follows:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35,15-35 rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each 1 to 2 hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is made tablet, capsule, granule or pill.
The preparation technology of the medicated wine of treatment rheumatism, rheumatoid disease, its step is as follows:
(1) with Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35, the 15-35 that rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12 is 36-flavor Glutinous to be added 52 ℃ to 56 ℃ pure grain wine and fully soaks 3 times, and each 1 month, it was stand-by to obtain 3 parts of medicated liquors respectively;
(2) with above-mentioned 3 parts of medicated liquor mixings, be prepared into medicated wine.
The preparation technology of treatment rheumatism of the present invention, rheumatoid medicine, its step is as follows:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is made capsule.
Amount of drug of the present invention is relevant with dosage form, patient's age and health status etc.For referencial use with capsule: oral, a 3-5 grain, 3 times on the one.Took in 10 minutes after meal, serveing on 3 months is a course of treatment.
The invention provides treatment rheumatism, rheumatoid medicine, is that raw material is made with the natural Chinese medicine, have evident in efficacy, stablize, have no side effect, taking convenience and advantage such as simple for production.
The specific embodiment
Embodiment 1
A kind of preparation of capsule of medicine for the treatment of rheumatism, rheumatoid disease:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is made capsule by general capsule method for making.
Embodiment 2
A kind of preparation of tablet of medicine for the treatment of rheumatism, rheumatoid disease:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is prepared into tablet by general tablet method for making.
Embodiment 3
A kind of preparation of granule of medicine for the treatment of rheumatism, rheumatoid disease:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is prepared into granule by general granule method for making.
Embodiment 4
A kind of preparation of pill of medicine for the treatment of rheumatism, rheumatoid disease:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is prepared into pill by general pill method for making.
Embodiment 5
A kind of preparation of medicated wine of medicine for the treatment of rheumatism, rheumatoid disease:
(1) with Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35, the 15-35 that rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12 is 36-flavor Glutinous to be added 52 ℃ to 56 ℃ pure grain wine and fully soaks 3 times, and each 1 month, it was stand-by to obtain 3 parts of medicated liquors respectively;
(2) with above-mentioned 3 parts of medicated liquor mixings, be prepared into medicated wine.
The clinical observation test of medicine of the present invention (capsule):
(1) physical data: accept patient's 536 examples for medical treatment, the age is at 25-55 between year.
(2) severity extent: long, the outbreak repeatedly of rheumatoid pathology, prolongedly do not heal, a plurality of arthralgia, deformity, joint function disturbance can't orthobiosis, and the blood test rheumatoid factor is positive, this is the fundamental difference of rheumatoid disease and rheumatism, and it is ill all around that the contact of the two shows that then the disease gene all centers on the joint.
(3) Therapeutic Method:
Every day, oral capsule was 3-5 time, each 4-6 grain, and between meal or took in 5 minutes after meal, 3 months is a course of treatment.
(4) efficacy assessment standard:
Cure: the arthralgia complete obiteration, blood test rheumatoid factor, erythrocyte sedimentation rate, anti-0 transfer feminine gender to; Take a turn for the better: arthralgia disappears substantially, and the blood test rheumatoid factor transfers the weak positive to, and erythrocyte sedimentation rate, anti-0 transfers feminine gender to; Invalid: arthralgia does not have significant change, and the position that maintains the original state or swell and ache increases, increases, blood test rheumatoid factor, erythrocyte sedimentation rate, anti-0 all positive;
5 therapeutic outcomes
Rheumatic arthritis swells and ache, clicking of joint, and dysfunction, promptly cure 1 course of treatment.
Rheumatoid arthrosis swells and ache, lopsided, dysfunction, and outbreak be can't take care of oneself repeatedly, takes 2-6 the course of treatment and cures.
Observe in 536 examples, cure 528 examples, 8 examples that take a turn for the better, cure rate is 98%, total effective rate reaches 100%.
Claims (8)
1. treat rheumatism for one kind, the medicine of rheumatoid disease is characterized in that it is the medicament of being made by the following weight proportion raw material: Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35,15-35 rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12.
2. according to right 1 described a kind of treatment rheumatism, the medicine of rheumatoid disease is characterized in that: it is to be made by following weight proportion raw material: Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10.
3. according to right 1 described a kind of medicine for the treatment of rheumatism, rheumatoid disease, it is characterized in that: described medicament is tablet, capsule, granule or pill.
4. according to right 1 described a kind of medicine for the treatment of rheumatism, rheumatoid disease, it is characterized in that: described medicament is a medicated wine.
5. a kind of medicine for the treatment of rheumatism, rheumatoid disease according to claim 3, it is characterized in that: described medicine is a capsule.
6. as claim 1 or 3 described a kind of preparation technologies that treat the medicine of rheumatism, rheumatoid disease, it is characterized in that its step is as follows:
(1) take by weighing each raw material by following formula ratio:
Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35,15-35 rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each 1 to 2 hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is made tablet, capsule, granule or pill with pharmaceutically acceptable carrier.
7. a kind of preparation technology who treats the medicine of rheumatism, rheumatoid disease according to claim 4 is characterized in that the preparation process of its medicated wine is as follows:
(1) with Radix Dipsaci 6-20, Radix Angelicae Sinensis 9-30, Rhizoma Et Radix Notopterygii 2-9, Radix Angelicae Pubescentis 2-9, Fructus Chaenomelis 2-9, Ramulus Cinnamomi 2-8, bar osmanthus 2-8, Radix Rehmanniae Preparata 9-30, Lycium barbarum L. 9-30, Rhizoma Atractylodis 2-10, Rhizoma Curcumae 2-9, Rhizoma Chuanxiong 2-9, Radix Polygoni Multiflori 2-6, Poria 9-30, Radix Codonopsis 15-35, bubble ginseng 15-35, Radix Ginseng 2-9, Rhizoma Corydalis 2-6, Rhizoma Cyperi 2-9, Radix Clematidis 2-9, Caulis Akebiae 2-6, Rhizoma Atractylodis Macrocephalae 6-20, Cortex Eucommiae 9-30, Rhizoma Cibotii 15-35, Radix Rubiae 2-6, Ramulus Uncariae Cum Uncis 2-9, Radix Gentianae Macrophyllae 3-12, Fructus Psoraleae 9-30, Semen Cuscutae 9-30, Fructus Ligustri Lucidi 12-35, Herba Lycopodii 2-9, Radix Morindae Officinalis 15-35, the 15-35 that rues greatly, Herba Cynomorii 15-35, Scorpio 9-12, Hirudo 9-12 is 36-flavor Glutinous to be added 52 ℃ to 56 ℃ pure grain wine and fully soaks 3 times, and each 1 month, it was stand-by to obtain 3 parts of medicated liquors respectively;
(2) with above-mentioned 3 parts of medicated liquor mixings, be prepared into medicated wine.
8. a kind of preparation technology who treats the medicine of rheumatism, rheumatoid disease according to claim 6 is characterized in that its step is as follows:
(1) take by weighing each raw material by following weight ratio:
Radix Dipsaci 13, Radix Angelicae Sinensis 19, Rhizoma Et Radix Notopterygii 5, Radix Angelicae Pubescentis 5, Fructus Chaenomelis 5, Ramulus Cinnamomi 5, bar osmanthus 5, Radix Rehmanniae Preparata 20, Lycium barbarum L. 20, Rhizoma Atractylodis 6, Rhizoma Curcumae 5, Rhizoma Chuanxiong 5, Radix Polygoni Multiflori 4, Poria 20, Radix Codonopsis 25, bubble ginseng 25, Radix Ginseng 5, Rhizoma Corydalis 4, Rhizoma Cyperi 5, Radix Clematidis 5, Caulis Akebiae 4, the Rhizoma Atractylodis Macrocephalae 13, the Cortex Eucommiae 20, Rhizoma Cibotii 25, Radix Rubiae 4, Ramulus Uncariae Cum Uncis 5, Radix Gentianae Macrophyllae 7, Fructus Psoraleae 20, Semen Cuscutae 20, Fructus Ligustri Lucidi 24, Herba Lycopodii 5, Radix Morindae Officinalis 25 rues 25 greatly, Herba Cynomorii 25, Scorpio 10, Hirudo 10;
(2) Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Fructus Chaenomelis, Ramulus Cinnamomi, bar osmanthus, Rhizoma Atractylodis, Rhizoma Curcumae, Rhizoma Corydalis, Rhizoma Chuanxiong, Rhizoma Cyperi, Radix Clematidis, Caulis Akebiae, Radix Rubiae, Ramulus Uncariae Cum Uncis, Radix Gentianae Macrophyllae, Herba Lycopodii, Scorpio, Hirudo are pulverized, mistake 120 mesh sieves get fine powder and coarse powder is stand-by;
(3) with above-mentioned coarse powder with interrupted, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Lycium barbarum L., Radix Polygoni Multiflori, Poria, Radix Codonopsis, bubble ginseng, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Rhizoma Cibotii, Fructus Psoraleae, Semen Cuscutae, Fructus Ligustri Lucidi, Radix Morindae Officinalis, rue greatly, Herba Cynomorii totally ten eight flavors decoct with water 3 times, each one to two hour, relative density 1.30 to 1.32 when collecting decoction, filtration, filtrate were concentrated into 60 ℃, got I;
(4) with above-mentioned fine powder and I mixing, drying is made capsule with pharmaceutically acceptable carrier.
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| CN105997497A (en) * | 2016-07-07 | 2016-10-12 | 南阳纯爱香颂美容有限公司 | Belly and back health-maintaining moxibustion therapy set and application method thereof |
| CN109045255A (en) * | 2018-09-13 | 2018-12-21 | 楚伟 | A kind of drug and preparation method thereof that clearing damp is warded off the cold |
| CN110613130A (en) * | 2019-10-23 | 2019-12-27 | 内蒙古普康药业有限公司 | Cistanche honey tablets and preparation method thereof |
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| Title |
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| 陈晓明，郭岳峰.类风湿性关节炎中医临床用药策略探讨.《世界中医药》.2008,第3卷(第1期),3-5. * |
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