CN107982421A - A kind of medicine for treating male sterility - Google Patents

A kind of medicine for treating male sterility Download PDF

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Publication number
CN107982421A
CN107982421A CN201711449334.7A CN201711449334A CN107982421A CN 107982421 A CN107982421 A CN 107982421A CN 201711449334 A CN201711449334 A CN 201711449334A CN 107982421 A CN107982421 A CN 107982421A
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China
Prior art keywords
parts
fruit
male sterility
medicine
tortoiseshell
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Pending
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CN201711449334.7A
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Chinese (zh)
Inventor
蒋伟哲
巫玲玲
付书婕
周媚
张卓
黄俊力
刘雪萍
王娜
陈昱晓
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NANNING DUOLING BIOTECHNOLOGY CO Ltd
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NANNING DUOLING BIOTECHNOLOGY CO Ltd
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Priority to CN201711449334.7A priority Critical patent/CN107982421A/en
Publication of CN107982421A publication Critical patent/CN107982421A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)

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  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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Abstract

The present invention relates to a kind of drug regimen for treating male sterility, thizoma curculiginis, HERBA EPIMEDII, Morinda officinalis, the fleece-flower root, saline cistanche, tortoiseshell, turtle shell, RHIZOMA POLYGONATI PREPARATA, Schisandra chinensis, plantain seed, psoralea corylifolia, raspberry, the fruit of glossy privet, the fruit of Chinese wolfberry, Fructus Corni, Semen Cuscutae, Radix Codonopsis, astragalus root, the dried rhizome of rehmannia, cultivated land is selected to be mended altogether for raw material negative and positive, rich in nutrition mends marrow and is used to treat male sterility.

Description

A kind of medicine for treating male sterility
Technical field
The present invention relates to a kind of drug regimen for treating male sterility, belongs to the field of Chinese medicines.
Background technology
Male infertility infertility pathogenic factor is complicated very much, and disease or factor can cause male sterility, according to semen efamination Result can be categorized as azoospermia, severe oligospermatism, oligospermatism, sperm count normality sterility, more sperm diseases and Asthenospermia disease etc..The medicament categories for the treatment of male infertility infertility are many, and most of western medicines are palliative.It is controlled Treatment approach is more to make endocrine therapy using raising sperm motility and sex hormone drug, sperm quality is improved, so as to mitigate disease Feelings symptom.It was verified that though this kind of medicine can alleviate illness to a certain extent, regret of effecting a permanent cure is reached there is hardly possible all the time.
The content of the invention
The purpose of the present invention is further excavate and utilize effective prescription in pools of traditional Chinese medicine, there is provided prescription uniqueness, The medicine of low, safe and reliable, the evident in efficacy treatment male infertility infertility of cost.
The present invention is achieved by the following technical solutions:
A kind of medicine for treating male sterility, is made of the raw material of following parts by weight:
10-14 parts of thizoma curculiginis, 10-14 parts of HERBA EPIMEDII, 10-14 parts of Morinda officinalis, 10-14 parts of the fleece-flower root, 30-40 parts of saline cistanche, tortoiseshell 8-10 parts, 8-10 parts of turtle shell, 10-14 parts of RHIZOMA POLYGONATI PREPARATA, 10-14 parts of Schisandra chinensis, 15-25 parts of plantain seed, 10-14 parts of psoralea corylifolia, cover 10-20 parts of basin, 10-14 parts of the fruit of glossy privet, 10-14 parts of the fruit of Chinese wolfberry, 10-20 parts of Fructus Corni, 10-20 parts of Semen Cuscutae, Radix Codonopsis 10-14 Part, 20-40 parts of astragalus root, 5-15 parts of the dried rhizome of rehmannia, 15-25 parts of cultivated land.
All tool has a better effect each component dosage in above-mentioned weight range.
Preferably:
12 parts of thizoma curculiginis, 12 parts of HERBA EPIMEDII, 12 parts of Morinda officinalis, 12 parts of the fleece-flower root, 35 parts of saline cistanche, 9 parts of tortoiseshell, 9 parts of turtle shell, manufacture-yellow 12 parts of essence, 12 parts of Schisandra chinensis, 20 parts of plantain seed, 12 parts of psoralea corylifolia, 15 parts of raspberry, 12 parts of the fruit of glossy privet, 12 parts of the fruit of Chinese wolfberry, mountain Zhu 15 parts of cornel, 15 parts of Semen Cuscutae, 12 parts of Radix Codonopsis, 30 parts of astragalus root, 10 parts of the dried rhizome of rehmannia, 20 parts of cultivated land.
The medicine of the present invention can use the conventional method of Chinese medicine preparation, and the active component of medicine of the present invention is added and is prepared Required various customary adjuvants are prepared into any conventional oral preparations during different dosage forms.Such as these bulk pharmaceutical chemicals can be ground into powder End is uniformly mixed to be made powder, pill or capsule, tablet is made;These bulk pharmaceutical chemicals decoctings, concentration decocting liquid can be lived and carried Take active ingredient that oral liquid is made, crushed after can also extracting solution be concentrated and dried and powder, capsule etc. is made.But these cannot For limiting the scope of the invention.
The present invention selects thizoma curculiginis, HERBA EPIMEDII, Morinda officinalis, the fleece-flower root, saline cistanche, tortoiseshell, turtle shell, RHIZOMA POLYGONATI PREPARATA, Schisandra chinensis, car Preceding son, psoralea corylifolia, raspberry, the fruit of glossy privet, the fruit of Chinese wolfberry, Fructus Corni, Semen Cuscutae, Radix Codonopsis, astragalus root, the dried rhizome of rehmannia, cultivated land are raw material, warp Scientific and reasonable compatibility, the effect of making each medicine, produces synergistic effect, so as to achieve the purpose that effectively to treat male sterility.
By the way that there is establishing-Yang production of sperm to the medicine of clinical observation, treatment male sterility of the invention, treat both principal and secondary aspect of disease, Good curative effect is not given birth to treatment male infertility, and is pure Chinese medicinal preparation, it is without any side effects, it is worthy to be popularized.
Embodiment:
Embodiment one:A kind of medicine for treating male sterility, contains the agents in units of parts by weight, 12 parts of thizoma curculiginis, celestial being Clever 12 parts of spleen, 12 parts of Morinda officinalis, 12 parts of the fleece-flower root, 35 parts of saline cistanche, 9 parts of tortoiseshell, 9 parts of turtle shell, 12 parts of RHIZOMA POLYGONATI PREPARATA, Schisandra chinensis 12 Part, 20 parts of plantain seed, 12 parts of psoralea corylifolia, 15 parts of raspberry, 12 parts of the fruit of glossy privet, 12 parts of the fruit of Chinese wolfberry, 15 parts of Fructus Corni, Semen Cuscutae 15 Part, 12 parts of Radix Codonopsis, 30 parts of astragalus root, 10 parts of the dried rhizome of rehmannia, 20 parts of cultivated land.
After above-mentioned all components are ground, 80 ~ 120 mesh sieves are crossed, the capsule of every drug containing 1.5g are made, for patient Oral, 2 times a day, 5 tablets each time, warm water delivery service, 20 days are 1 course for the treatment of, avoid during medication pungent, peppery, greasy food and Tobacco and wine.
Embodiment two:Preparation and the instructions of taking of the present embodiment medicine are as in the first embodiment, difference is:One kind treatment The medicine of male sterility, containing the agents in units of parts by weight, 15 parts of thizoma curculiginis, 15 parts of HERBA EPIMEDII, 15 parts of Morinda officinalis, what 15 parts of the tuber of multiflower knotweed, 40 parts of saline cistanche, 12 parts of tortoiseshell, 12 parts of turtle shell, 15 parts of RHIZOMA POLYGONATI PREPARATA, 15 parts of Schisandra chinensis, 25 parts of plantain seed, psoralea corylifolia 15 parts, 20 parts of raspberry, 15 parts of the fruit of glossy privet, 15 parts of the fruit of Chinese wolfberry, 20 parts of Fructus Corni, 20 parts of Semen Cuscutae, 15 parts of Radix Codonopsis, astragalus root 35 Part, 12 parts of the dried rhizome of rehmannia, 25 parts of cultivated land
Embodiment three:Preparation and the instructions of taking of the present embodiment medicine are as in the first embodiment, difference is:One kind treats male The medicine of infertility, contains the agents in units of parts by weight, 10 parts of thizoma curculiginis, 10 parts of HERBA EPIMEDII, 10 parts of Morinda officinalis, the fleece-flower root 10 parts, 33 parts of saline cistanche, 6 parts of tortoiseshell, 6 parts of turtle shell, 10 parts of RHIZOMA POLYGONATI PREPARATA, 10 parts of Schisandra chinensis, 18 parts of plantain seed, 10 parts of psoralea corylifolia, 12 parts of raspberry, 10 parts of the fruit of glossy privet, 10 parts of the fruit of Chinese wolfberry, 12 parts of Fructus Corni, 12 parts of Semen Cuscutae, 12 parts of Radix Codonopsis, 30 parts of astragalus root, life 10 parts of ground, 20 parts of cultivated land.

Claims (2)

1. a kind of medicine for treating male sterility, it is characterised in that be made of the raw material of following parts by weight:
10-14 parts of thizoma curculiginis, 10-14 parts of HERBA EPIMEDII, 10-14 parts of Morinda officinalis, 10-14 parts of the fleece-flower root, 30-40 parts of saline cistanche, tortoiseshell 8-10 parts, 8-10 parts of turtle shell, 10-14 parts of RHIZOMA POLYGONATI PREPARATA, 10-14 parts of Schisandra chinensis, 15-25 parts of plantain seed, 10-14 parts of psoralea corylifolia, cover 10-20 parts of basin, 10-14 parts of the fruit of glossy privet, 10-14 parts of the fruit of Chinese wolfberry, 10-20 parts of Fructus Corni, 10-20 parts of Semen Cuscutae, Radix Codonopsis 10-14 Part, 20-40 parts of astragalus root, 5-15 parts of the dried rhizome of rehmannia, 15-25 parts of cultivated land.
2. a kind of medicine for treating male sterility according to claim 1, it is characterised in that by the raw material of following parts by weight It is made:
12 parts of thizoma curculiginis, 12 parts of HERBA EPIMEDII, 12 parts of Morinda officinalis, 12 parts of the fleece-flower root, 35 parts of saline cistanche, 9 parts of tortoiseshell, 9 parts of turtle shell, manufacture-yellow 12 parts of essence, 12 parts of Schisandra chinensis, 20 parts of plantain seed, 12 parts of psoralea corylifolia, 15 parts of raspberry, 12 parts of the fruit of glossy privet, 12 parts of the fruit of Chinese wolfberry, mountain Zhu 15 parts of cornel, 15 parts of Semen Cuscutae, 12 parts of Radix Codonopsis, 30 parts of astragalus root, 10 parts of the dried rhizome of rehmannia, 20 parts of cultivated land.
CN201711449334.7A 2017-12-28 2017-12-28 A kind of medicine for treating male sterility Pending CN107982421A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117357621A (en) * 2023-11-21 2024-01-09 江苏省中医院 Traditional Chinese medicine compound for improving sperm energy metabolism and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814251A (en) * 2005-04-28 2006-08-09 陈宏棕 Chinese medicine preparation for treating male sterility
CN104161895A (en) * 2014-06-29 2014-11-26 苟晓龙 A sperm-producing decoction

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1814251A (en) * 2005-04-28 2006-08-09 陈宏棕 Chinese medicine preparation for treating male sterility
CN104161895A (en) * 2014-06-29 2014-11-26 苟晓龙 A sperm-producing decoction

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
滕黎明: "温肾育子汤治疗男性不育症50例", 《湖南中医杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117357621A (en) * 2023-11-21 2024-01-09 江苏省中医院 Traditional Chinese medicine compound for improving sperm energy metabolism and preparation method and application thereof

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Application publication date: 20180504