CN105687672A

CN105687672A - Traditional Chinese medicine composition for treating mastitis and mammary gland hyperplasia and preparation method thereof

Info

Publication number: CN105687672A
Application number: CN201610151587.5A
Authority: CN
Inventors: 韩聪慧
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-03-17
Filing date: 2016-03-17
Publication date: 2016-06-22

Abstract

The invention provides a traditional Chinese medicine composition for treating mastitis and mammary gland hyperplasia and a preparation method thereof, and belongs to the technical field of Chinese herbal medicine. The traditional Chinese medicine composition is prepared from, by weight, 10-14 parts of radix angelicae, 10-14 parts of bulbs of fritillary, 10-14 parts of radix saposhnikoviae, 13-16 parts of roots of common peony, 18-22 parts of radix angelica sinensis, 8-10 parts of liquorice roots, 6-8 parts of myrsine semiserrata fruit, 10-14 parts of squama manis, 13-16 parts of radix trichosanthis, 10-14 parts of frankincense, 10-14 parts of myrrh, 23-27 parts of flos lonicerae, 8-10 parts of pericarpium citri reticulatae, 8-10 parts of radix bupleuri and 13-16 parts of rhizoma corydalis. The invention further discloses the preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the effects of clearing heat, removing toxicity, relieving swelling and disintegrating mass, can treat the mammary gland hyperplasia, the mastitis, breast nodules and an initial stage of a breast cancer, is high in penetrating power and has the obvious inhibition effect.

Description

A kind of Chinese medicine composition treating mastitis and cyclomastopathy and preparation method thereof

Technical field

The invention belongs to field of Chinese herbal medicine technology, relate to a kind of Chinese medicine treating mastitis and cyclomastopathy, specifically a kind of Chinese medicine composition treating mastitis and cyclomastopathy and preparation method thereof。

Background technology

Mastitis are the diseases that women is common, are a kind of big diseases anxious, painful of falling ill, can be divided into acute purulent mammitis, mammary areola other fistula, plasma cell mastitis etc. according to the difference of the different pathogeny of the cause of disease。Acute purulent mammitis often betides age of sucking, particularly in 1～2 month puerperal of primipara, therefore cry again acute age of sucking or puerperal suppurative mastitis, the traditional Chinese medical science is called " acute mastitis "。The sickness rate of primipara's acute mastitis up to 2%～4%, more than multipara's mastitis 1 times。Antibacterial of occurring together infects and falls ill human milk silt, shows in acute inflammation, red and swollen heat pain, the high heat of shiver with cold, early stage can maneuver milk ejection, treatment by Chinese herbs, then need incision and drainage after suppurating。After morbidity, not only puerpera is painful abnormal, and can not continue suckling, affects the health of baby。Therefore, if giving Western medicine, to the adverse effect that nourished the baby on mother's milk, so mostly advising Chinese medicine。Most Chinese medicines are natural plants and the not high violent person's prescription of the entirely selectable property of medicine of Chinese medicine for the treatment of primary disease, breast feeding will not be produced harmful effect。Even if need not breastfeeding patient, use the antibiotic therapy primary disease of heavy dose, also bring along " fastbacteria problem ", the traditional Chinese medical science then has evades the advantage of many toxic and side effects that doctor trained in Western medicine uses a large amount of antibiotic to bring。

Summary of the invention

In order to comply with theory of Chinese medical science, seek a kind of Chinese medicine composition not having toxic and side effects, we devise a kind of Chinese medicine composition treating mastitis and cyclomastopathy and preparation method thereof, utilize the Chinese medicine composition that this preparation method produces to have heat-clearing and toxic substances removing, the effect of relieving swelling and disintegrating mass, treatment cyclomastopathy, mastitis, breast nodule, the breast carcinoma initial stage, this medicine penetration power is strong, has obvious inhibiting effect。

The technical solution used in the present invention is: a kind of Chinese medicine composition treating mastitis and cyclomastopathy, it is important to: containing, for example the component of lower parts by weight proportion relation in this Chinese medicine composition: Radix Angelicae Dahuricae 10-14 part, Bulbus Fritillariae Uninbracteatae 10-14 part, Radix Saposhnikoviae 10-14 part, Radix Paeoniae Rubra 13-16 part, Radix Angelicae Sinensis 18-22 part, Radix Glycyrrhizae 8-10 part, acupuncture 6-8 part, Squama Manis 10-14 part, Radix Trichosanthis 13-16 part, Olibanum 10-14 part, Myrrha 10-14 part, Flos Lonicerae 23-27 part, Pericarpium Citri Reticulatae 8-10 part, Radix Bupleuri 8-10 part, Rhizoma Corydalis 13-16 part。

Preferably, containing, for example the component of lower parts by weight proportion relation in this Chinese medicine composition: the Radix Angelicae Dahuricae 12 parts, Bulbus Fritillariae Uninbracteatae 12 parts, Radix Saposhnikoviae 12 parts, Radix Paeoniae Rubra 15 parts, Radix Angelicae Sinensis 20 parts, 9 parts of Radix Glycyrrhizae, acupuncture 7 parts, Squama Manis 12 parts, Radix Trichosanthis 15 parts, Olibanum 12 parts, Myrrha 12 parts, Flos Lonicerae 25 parts, Pericarpium Citri Reticulatae 9 parts, Radix Bupleuri 9 parts, Rhizoma Corydalis 15 parts。

The preparation method preparing above-mentioned Chinese medicine composition, step includes:

(1), by weight proportion relation weigh each component, each component is crushed to 100～200 orders one by one；

(2), by Bulbus Fritillariae Uninbracteatae with humus flava usta concoct micro-Huang, Squama Manis rough sand slow fire concoct micro-Huang, Rhizoma Corydalis, Myrrha, Olibanum respectively through steaming with vinegar, dry, micro-stir-fry；

(3) take each component after step (1), (2) process, be mixed, beat powder to 180-220 order to obtain finished product。

Wherein, described steaming with vinegar steams 3-9 time, each 8-12min。

Preferably, described steaming with vinegar steams 3 times, each 10min。

The beneficial effects of the present invention is: 1, the preparation method of Chinese medicine of the present invention it is crucial that the process of preparing Chinese medicine skill of medicine, the multiple concocting method of Chinese medicine to add some auxiliary spices, some medicines are conducive to stable drug effect through the process of preparing Chinese medicine, after heat treated, can prevent glycoside hydrolysis from avoiding important active constituent content to decline, but generally it is for improving curative effect, potentiation。If, Bulbus Fritillariae Uninbracteatae must be that humus flava usta is concocted, Squama Manis needs rough sand to have slow fire to concoct gradually to form, and Rhizoma Corydalis, Myrrha, Olibanum needs to concoct after nine steam with vinegar, so that medicine effect strengthens。2, the formula of Chinese medicine of the present invention it is crucial that the control of the selection of component and pharmaceutical quantities。The Radix Angelicae Dahuricae, expelling pathogenic wind from the body surface, pain relieving, dampness, have antipyretic, antiinflammatory, antitumaous effect。Bulbus Fritillariae Uninbracteatae, has heat clearing away, vanishing sputum and dispelling knot, analgesic activity。Radix Saposhnikoviae, expelling pathogenic wind from the body surface, pain relieving, eliminating evil and just do not hinder, consolidating superficial resistance and do not stay heresy, play the effect of strengthening vital QI to eliminate pathogenic factors altogether with Bulbus Fritillariae Uninbracteatae。Radix Paeoniae Rubra, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, there is antiplatelet to condense mammary gland, antithrombus formation, improve microcirculation, coronary artery dilator, antiinflammatory, analgesia, antiulcer etc. has multiple pharmacological effect。Radix Angelicae Sinensis, enriches blood, and invigorates blood circulation, pain relieving, has anti-peripheral blood vessel smooth muscle spasm for mammary gland, increases blood flow, improves peripheral circulation, have analgesia, antiinflammatory action。Each medicine in inventive formulation complements each other so that it is medicine has heat-clearing and toxic substances removing, the effect of relieving swelling and disintegrating mass, treats cyclomastopathy, mastitis, breast nodule, and breast carcinoma is strong from the beginning of, this medicine penetration power, has obvious inhibiting effect。It is known that pharmaceutical quantities is extremely paid attention to by the traditional Chinese medical science successive dynasties, having saying of " traditional Chinese medical science do not pass secret be in that dosage ", same to Herba indigoferae Pseudotinctoriae, consumption is different, then effect differs。Such as Radix Gentianae in a small amount, having bitter digestion promoting function of mending, the big then bitter cold of amount is upset one's stomach。In the compatibility of medicines in a prescription, often Herba indigoferae Pseudotinctoriae consumption number just determine that the primary efficacy that whole prescription produces is different。The property of medicine of each component used by the present invention is all known by common people, but, the consumption of each component can not be ignored, and is otherwise difficult to receive intended therapeutic effect。Each group flavour of a drug post in inventive formulation is clearly demarcated, complement each other, give full play to the exclusive compound compatibility medication of Chinese medicine if the sexology research methodology of analyzing mentally arranged forces in certain formation is to marrow, mastitis no matter symptom weight, good curative effect can be obtained, provide a kind of new selection for clinical application。

Detailed description of the invention

With embodiment, the present invention is described in detail below。

Embodiment 1: weigh each component by following parts by weight proportion relation: the Radix Angelicae Dahuricae 12 parts, Bulbus Fritillariae Uninbracteatae 12 parts, Radix Saposhnikoviae 12 parts, Radix Paeoniae Rubra 15 parts, Radix Angelicae Sinensis 20 parts, 9 parts of Radix Glycyrrhizae, acupuncture 7 parts, Squama Manis 12 parts, Radix Trichosanthis 15 parts, Olibanum 12 parts, Myrrha 12 parts, Flos Lonicerae 25 parts, Pericarpium Citri Reticulatae 9 parts, Radix Bupleuri 9 parts, Rhizoma Corydalis 15 parts。

Embodiment 2: weigh each component by following parts by weight proportion relation: the Radix Angelicae Dahuricae 10 parts, Bulbus Fritillariae Uninbracteatae 10 parts, Radix Saposhnikoviae 10 parts, Radix Paeoniae Rubra 13 parts, Radix Angelicae Sinensis 18 parts, 8 parts of Radix Glycyrrhizae, acupuncture 6 parts, Squama Manis 10 parts, Radix Trichosanthis 13 parts, Olibanum 10 parts, Myrrha 10 parts, Flos Lonicerae 23 parts, Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 8 parts, Rhizoma Corydalis 13 parts。

Embodiment 3: weigh each component by following parts by weight proportion relation: the Radix Angelicae Dahuricae 14 parts, Bulbus Fritillariae Uninbracteatae 14 parts, Radix Saposhnikoviae 14 parts, Radix Paeoniae Rubra 16 parts, Radix Angelicae Sinensis 22 parts, 10 parts of Radix Glycyrrhizae, acupuncture 8 parts, Squama Manis 14 parts, Radix Trichosanthis 16 parts, Olibanum 14 parts, Myrrha 14 parts, Flos Lonicerae 27 parts, Pericarpium Citri Reticulatae 10 parts, Radix Bupleuri 10 parts, Rhizoma Corydalis 16 parts。

Embodiment 4: weigh each component by following parts by weight proportion relation: the Radix Angelicae Dahuricae 13 parts, Bulbus Fritillariae Uninbracteatae 13 parts, Radix Saposhnikoviae 13 parts, Radix Paeoniae Rubra 14 parts, Radix Angelicae Sinensis 21 parts, 9 parts of Radix Glycyrrhizae, acupuncture 7 parts, Squama Manis 13 parts, Radix Trichosanthis 14 parts, Olibanum 13 parts, Myrrha 13 parts, Flos Lonicerae 14 parts, Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 9 parts, Rhizoma Corydalis 15 parts。

Afterwards, Bulbus Fritillariae Uninbracteatae humus flava usta in component embodiment 1,2,3,4 taken respectively concocts micro-Huang, and Squama Manis needs rough sand slow fire to concoct micro-Huang gradually, and Rhizoma Corydalis steaming with vinegar steams 3 times, each 10min, dries afterwards, then micro-stir-fry；Myrrha steaming with vinegar steams 3 times, and each 10min dries, then micro-stir-fry afterwards；, Olibanum steaming with vinegar steam 3 times, each 10min, dry afterwards, then micro-stir-fry；

Gained Bulbus Fritillariae Uninbracteatae, Squama Manis, Rhizoma Corydalis, Myrrha, Olibanum will mix with remaining ingredient, and then beat powder and get product to 180-220 order after concocting again。

For showing the Chinese medicine composition of the present invention therapeutic effect to mastitis and cyclomastopathy, from being in hospital and internal clinic selects the case that 200 example mastitis degree are identical。

Therapeutic scheme: 200 example patients are divided into A, B, C, D tetra-groups, and every 50 examples are one group, and A group takes the powder that embodiment 1 is made, each takes 200-400ml, daily three times, take four courses for the treatment of, one of them moon is a course for the treatment of。B group takes the powder that embodiment 2 is made, each takes 200-400ml, daily three times, takes four courses for the treatment of, and one of them moon is a course for the treatment of。C group takes the powder that embodiment 3 is made, each takes 200-400ml, daily three times, takes four courses for the treatment of, and one of them moon is a course for the treatment of。D group takes the powder that embodiment 4 is made, each takes 200-400ml, daily three times, takes four courses for the treatment of, and one of them moon is a course for the treatment of。

Treatment standard:

Recovery from illness: mastitis symptom all disappears, it is abnormal that inspection has no index of correlation；

Evident in efficacy: mastitis symptom substantially alleviates, test rating has considerable degree of improvement simultaneously；

There is certain effect: mastitis symptom alleviates to some extent, or test rating makes moderate progress；

Invalid: still, test rating is without change for mastitis symptom。

Therapeutic outcome:

A group: 40 examples of fully recovering, 8 examples evident in efficacy, there are certain effect 2 example, invalid 0 example。

B group: 38 examples of fully recovering, 10 examples evident in efficacy, there are certain effect 2 example, invalid 0 example。

C group: 39 examples of fully recovering, 9 examples evident in efficacy, there are certain effect 2 example, invalid 0 example。

D group: 40 examples of fully recovering, 7 examples evident in efficacy, there are certain effect 3 example, invalid 0 example。

In sum, the Chinese medicine composition of the present invention is evident in efficacy to the treatment mastopathy such as mastitis, cyclomastopathy, and medicine is full Chinese medicine formula, is the optimum selection of patient medication treatment age of sucking。

Claims

1. the Chinese medicine composition treating mastitis and cyclomastopathy, it is characterised in that: containing, for example the component of lower parts by weight proportion relation in this Chinese medicine composition: Radix Angelicae Dahuricae 10-14 part, Bulbus Fritillariae Uninbracteatae 10-14 part, Radix Saposhnikoviae 10-14 part, Radix Paeoniae Rubra 13-16 part, Radix Angelicae Sinensis 18-22 part, Radix Glycyrrhizae 8-10 part, acupuncture 6-8 part, Squama Manis 10-14 part, Radix Trichosanthis 13-16 part, Olibanum 10-14 part, Myrrha 10-14 part, Flos Lonicerae 23-27 part, Pericarpium Citri Reticulatae 8-10 part, Radix Bupleuri 8-10 part, Rhizoma Corydalis 13-16 part。

2. a kind of Chinese medicine composition treating mastitis and cyclomastopathy according to claim 1, it is characterised in that: containing, for example the component of lower parts by weight proportion relation in this Chinese medicine composition: the Radix Angelicae Dahuricae 12 parts, Bulbus Fritillariae Uninbracteatae 12 parts, Radix Saposhnikoviae 12 parts, Radix Paeoniae Rubra 15 parts, Radix Angelicae Sinensis 20 parts, 9 parts of Radix Glycyrrhizae, acupuncture 7 parts, Squama Manis 12 parts, Radix Trichosanthis 15 parts, Olibanum 12 parts, Myrrha 12 parts, Flos Lonicerae 25 parts, Pericarpium Citri Reticulatae 9 parts, Radix Bupleuri 9 parts, Rhizoma Corydalis 15 parts。

3. the preparation method of preparation Chinese medicine composition described in claim 1, it is characterised in that: this preparation method step includes:

4. preparation method according to claim 3, it is characterised in that: described steaming with vinegar steams 3-9 time, each 8-12min。

5. preparation method according to claim 3, it is characterised in that: described steaming with vinegar steams 3 times, each 10min。