CN101959602A - 分离血浆的设备 - Google Patents

分离血浆的设备 Download PDF

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Publication number
CN101959602A
CN101959602A CN200980106816XA CN200980106816A CN101959602A CN 101959602 A CN101959602 A CN 101959602A CN 200980106816X A CN200980106816X A CN 200980106816XA CN 200980106816 A CN200980106816 A CN 200980106816A CN 101959602 A CN101959602 A CN 101959602A
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CN
China
Prior art keywords
equipment
passage
channel
sample liquids
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200980106816XA
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English (en)
Chinese (zh)
Inventor
格特·布兰肯斯滕
霍尔格·巴托斯
拉尔夫-彼得·彼得斯
克里斯琴·舍恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Microparts GmbH
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Boehringer Ingelheim Microparts GmbH
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Filing date
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Application filed by Boehringer Ingelheim Microparts GmbH filed Critical Boehringer Ingelheim Microparts GmbH
Publication of CN101959602A publication Critical patent/CN101959602A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
    • B01D29/014—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements with curved filtering elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
    • B01D29/05—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/088—Microfluidic devices comprising semi-permeable flat membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2201/00—Details relating to filtering apparatus
    • B01D2201/04—Supports for the filtering elements
    • B01D2201/0415—Details of supporting structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2201/00—Details relating to filtering apparatus
    • B01D2201/44—Special measures allowing the even or uniform distribution of fluid along the length of a conduit
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • External Artificial Organs (AREA)
CN200980106816XA 2008-02-27 2009-02-26 分离血浆的设备 Pending CN101959602A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008011339 2008-02-27
DE102008011339.5 2008-02-27
PCT/EP2009/001383 WO2009106331A2 (de) 2008-02-27 2009-02-26 Vorrichtung zur plasmaseparation

Publications (1)

Publication Number Publication Date
CN101959602A true CN101959602A (zh) 2011-01-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980106816XA Pending CN101959602A (zh) 2008-02-27 2009-02-26 分离血浆的设备

Country Status (10)

Country Link
US (2) US9539572B2 (enExample)
EP (1) EP2268405B1 (enExample)
JP (1) JP5475692B2 (enExample)
CN (1) CN101959602A (enExample)
AU (1) AU2009218752B2 (enExample)
BR (1) BRPI0907148B1 (enExample)
CA (1) CA2716411C (enExample)
MX (1) MX346456B (enExample)
RU (1) RU2523681C2 (enExample)
WO (1) WO2009106331A2 (enExample)

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CN103033609A (zh) * 2011-09-30 2013-04-10 奥索临床诊断有限公司 用于免疫血液学测试元件的一次性箔冲头
CN107469477A (zh) * 2016-06-07 2017-12-15 杨国勇 流体处理装置及其制备方法
CN107525765A (zh) * 2016-06-15 2017-12-29 优志旺电机株式会社 微流路芯片及检体浓度测定装置
CN109641210A (zh) * 2016-08-12 2019-04-16 高丽大学校产学协力团 微流体元件及其制造方法
CN109701408A (zh) * 2017-10-25 2019-05-03 台达电子工业股份有限公司 粒子凝集混合方法及混合设备
CN114761103A (zh) * 2019-10-02 2022-07-15 奥斯龙-明士克公司 血液成分收集和分离介质、包括所述介质的血液成分收集和分离装置以及实施所述介质的血液成分分离和提取方法

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Publication number Priority date Publication date Assignee Title
CN103033609A (zh) * 2011-09-30 2013-04-10 奥索临床诊断有限公司 用于免疫血液学测试元件的一次性箔冲头
CN107469477A (zh) * 2016-06-07 2017-12-15 杨国勇 流体处理装置及其制备方法
CN107525765A (zh) * 2016-06-15 2017-12-29 优志旺电机株式会社 微流路芯片及检体浓度测定装置
CN109641210A (zh) * 2016-08-12 2019-04-16 高丽大学校产学协力团 微流体元件及其制造方法
CN109641210B (zh) * 2016-08-12 2021-03-30 高丽大学校产学协力团 微流体元件及其制造方法
CN109701408A (zh) * 2017-10-25 2019-05-03 台达电子工业股份有限公司 粒子凝集混合方法及混合设备
CN114761103A (zh) * 2019-10-02 2022-07-15 奥斯龙-明士克公司 血液成分收集和分离介质、包括所述介质的血液成分收集和分离装置以及实施所述介质的血液成分分离和提取方法

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BRPI0907148B1 (pt) 2021-01-12
CA2716411A1 (en) 2009-09-03
EP2268405A2 (de) 2011-01-05
US20110011781A1 (en) 2011-01-20
CA2716411C (en) 2015-11-24
RU2010139578A (ru) 2012-04-10
WO2009106331A3 (de) 2010-02-25
US10363559B2 (en) 2019-07-30
JP5475692B2 (ja) 2014-04-16
AU2009218752B2 (en) 2014-07-10
US9539572B2 (en) 2017-01-10
BRPI0907148A2 (pt) 2020-08-25
EP2268405B1 (de) 2017-01-04
WO2009106331A2 (de) 2009-09-03
MX346456B (es) 2017-03-21
JP2011513718A (ja) 2011-04-28
RU2523681C2 (ru) 2014-07-20
WO2009106331A4 (de) 2010-04-22
AU2009218752A1 (en) 2009-09-03
US20170165666A1 (en) 2017-06-15
MX2010009331A (es) 2010-09-14

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Application publication date: 20110126