CN101953994A - Chinese medicament for treating luekopenia after concurrent chemoradiotherapy - Google Patents

Chinese medicament for treating luekopenia after concurrent chemoradiotherapy Download PDF

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CN101953994A
CN101953994A CN 201010502454 CN201010502454A CN101953994A CN 101953994 A CN101953994 A CN 101953994A CN 201010502454 CN201010502454 CN 201010502454 CN 201010502454 A CN201010502454 A CN 201010502454A CN 101953994 A CN101953994 A CN 101953994A
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radix
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chinese medicine
chemicotherapy
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CN101953994B (en
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于淑萍
宫兆妮
王大鹏
迟君华
慈明伟
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于淑萍
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Abstract

The invention relates to a Chinese medicament for treating luekopenia after concurrent chemoradiotherapy, which consists of the following raw materials by weight: 10 to 12 grams of American ginseng, 10 to 12 grams of fried atractylodes macrocephala Koidz., 30 to 35 grams of astragalus, 12 to 14 grams of medlar, 8 to 10 grams of malaytea scurfpea fruit, 10 to 12 grams of tangerine peel, 10 to 12 grams of white paeony root, 10 to 13 grams of Chinese angelica, 28 to 33 grams of siberian solomonseal rhizome and 6 to 8 grams of mix-fried licorice. The Chinese medicament of the invention has the characteristics of simple and rational preparation, good curative effects, wide medicinal sources, convenient use, no toxic or side effect, high curative ratio and the overall response rate of over 98 percent.

Description

Leukopenic Chinese medicine behind a kind of treatment chemicotherapy
Technical field
The present invention relates to the field of Chinese medicines, leukopenic Chinese medicine behind a kind of treatment chemicotherapy.
Background technology
Chemicotherapy is one of main treatment means of malignant tumor, but chemicotherapy is when killing and wounding cancerous cell, also to the normal structure of body, cause great infringement as the bone marrow system, often cause leukopenia, make chemicotherapy be forced to decrement or termination, and easy concurrent infection.Leukopenia is meant that the peripheral blood leucocyte counting continues to be lower than 4 * 10 9/ L.The patient shows as fatigue and weakness, lassitude, lusterless complexion, breathe hard lazy speech, inappetence, pale tongue with white fur, deficient and weak pulse etc.The traditional Chinese medical science thinks that the leukopenia that chemicotherapy causes belongs to " asthenia " category.
Summary of the invention
Purpose of the present invention just provides a kind of leukopenic Chinese medicine that chemicotherapy causes for the treatment of, and with the treatment of benefiting vital QI and blood method, stable curative effect is difficult for recurrence, the cure rate height, and have no side effect.
For achieving the above object, leukopenic Chinese medicine behind a kind of treatment chemicotherapy is characterized in that it is made up of the component of following raw materials in weight drug ratio: Radix Panacis Quinquefolii 10-12g, Rhizoma Atractylodis Macrocephalae (parched) 10-12g, Radix Astragali 30-35g, Fructus Lycii 12-14g, Fructus Psoraleae 8-10g, Pericarpium Citri Reticulatae 10-12g, Radix Paeoniae Alba 10-12g, Radix Angelicae Sinensis 10-13g, Rhizoma Polygonati 28-33g, Radix Glycyrrhizae Preparata 6-8g.
Chinese medicine preparation of the present invention is simple, reasonable, good effect, and the medicine source is wide, and is easy to use, without any side effects, the cure rate height.
The Radix Astragali among the present invention, Radix Panacis Quinquefolii benefiting QI and nourishing blood are monarch drug altogether; " medication on the analogy of natural things ": " Radix Panacis Quinquefolii can tonifying the lung in vigour, the prosperous then four dirty gas of lung qi are all prosperous, smart spontaneous and shape is from containing, so all gas of lung master is also." " pearl sac ": " and the sweet Wen Chunyang of the Radix Astragali, it is with having five: mend all empty deficiencies, one also; Benefit vigour, two also; Strong taste, three also ..." be equipped with Rhizoma Atractylodis Macrocephalae (parched), Rhizoma Polygonati spleen invigorating eliminating dampness by diuresis helps ginseng, stilbene replenishing QI to invigorate the spleen, the joint venture of nourishing blood of Radix Angelicae Sinensis, the Radix Paeoniae Alba, essence is added in Fructus Lycii, Fructus Psoraleae the kidney invigorating, Pericarpium Citri Reticulatae circulation of qi promoting spleen invigorating works in the arteries and veins nutrient blood and circulates, Radix Glycyrrhizae Preparata is for making, QI invigorating and in, coordinating the actions of various ingredients in a prescription.Full side share have strengthening the body resistance, kidney and spleen invigorating, the effect of filling out marrow yin nourishing, benefiting QI and nourishing blood.
The dosage form of Chinese medicine of the present invention is the decocting decoction, manufacture method is: get raw material of Chinese medicine, at room temperature above-mentioned 10 kinds of Chinese herbal medicine are added water to 900-1000ml, soaked 4 hours, and boiled slow fire then with high heat and decoct to about 100-120 minute, remove slag about filtrate 200ml, Chinese medicine slag is added water 300-400ml again, decoct 30-40 minute, remove slag about filtrate 100ml, decoct altogether about medicine soup 300ml for twice and to mix.Divide twice (medicine) being taken before meal sooner or later every day, about each oral 150ml.
The present invention verifies that through clinical practice taking medicine 15 days is a course of treatment, a lighter's produce effects course of treatment, and heavy person is a produce effects two courses of treatment.Total effective rate is more than 98%.
The specific embodiment
Embodiment 1: leukopenic Chinese medicine behind a kind of treatment chemicotherapy, it is characterized in that it is made up of the component of following raw materials in weight drug ratio: Radix Panacis Quinquefolii 10-12g, Rhizoma Atractylodis Macrocephalae (parched) 10-12g, Radix Astragali 30-35g, Fructus Lycii 12-14g, Fructus Psoraleae 8-10g, Pericarpium Citri Reticulatae 10-12g, Radix Paeoniae Alba 10-12g, Radix Angelicae Sinensis 10-13g, Rhizoma Polygonati 28-33g, Radix Glycyrrhizae Preparata 6-8g.
Embodiment 2: leukopenic Chinese medicine behind a kind of treatment chemicotherapy, it is Radix Panacis Quinquefolii 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Astragali 30g, Fructus Lycii 12g, Fructus Psoraleae 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Angelicae Sinensis 10g, Rhizoma Polygonati 30g, Radix Glycyrrhizae Preparata 6g preferably.
Leukopenic Chinese medicine clinical efficacy is summed up behind a kind of treatment chemicotherapy:
One, physical data: decoction of the present invention is sutable for men, women, and children to be taken, and treats over one hundred routine patient.
Two, diagnostic criteria: leukopenic tumor patient behind the chemicotherapy.General clinical manifestation is fatigue and weakness, lusterless complexion, breathe hard lazy speech, inappetence, and laboratory examination shows that leukocyte is lower than 4 * 10 9/ L.
Three, making and method of administration: manufacture method is: get raw material of Chinese medicine, at room temperature above-mentioned 10 kinds of Chinese herbal medicine are added water to 900-1000ml, soaked 4 hours, boiling slow fire then with high heat decocts to about 100-120 minute, remove slag about filtrate 200ml, Chinese medicine slag is added water 300-400ml again, decoct 30-40 minute, remove slag about filtrate 100ml, decoct altogether about medicine soup 300ml for twice and to mix.Divide twice (medicine) being taken before meal sooner or later every day, about each oral 150ml.
Four, curative effect determinate standard:
Produce effects: total white blood cells ﹥ 4 * 10 9/ L, or by ﹤ 2.0 * 10 9/ L rises and reaches 4 * 10 9/ L stablized more than 2 weeks.Clinical symptoms significantly alleviates or disappears.
Effectively: total white blood cells is than the preceding rising 0.5-1.0 of treatment * 10 9/ L, or rise to 3.0 * 10 9/ L stablized more than 2 weeks, and clinical symptoms takes a turn for the better.
Invalid: total white blood cells does not have obvious rising or does not rise counter falling, and clinical symptoms does not have improvement.
Five, therapeutic effect: taking medicine 15 days is a course of treatment, a lighter's produce effects course of treatment, and heavy person is a produce effects two courses of treatment.Total effective rate is more than 98% according to statistics.
Six, model case:
1, open XX, be in hospital because of pulmonary carcinoma in February, 2008, carry out chemotherapy second round after leukocyte reduce to 1.5 * 10 9/ L, sense fatigue and weak, lusterless complexion, breathe hard lazy speech, inappetence, pale tongue with white fur, deficient and weak pulse.Took decoction of the present invention 15 days, leukocyte rises to 4.5 * 10 9/ L continues and obeyed 15 days, and all diseases disappear, and leukocyte rises to 5.8 * 10 9/ L follows up a case by regular visits to the not recurrence again of 6 cycle end of chemotherapy.
2, all XX, woman, 50 years old, go to a doctor in May, 2008, leukopenia appears in breast carcinoma postoperative chemicotherapy repeatedly, causes chemicotherapy normally not carry out, use the leucocyte increasing agent poor effect, took Chinese medicine decoction of the present invention 15 days, leukocyte rises to normally, after consolidate a course of treatment, finish chemicotherapy smoothly, not recurrence again.
3, king XX, man, 10 years old, nephroblastoma postoperative chemotherapy, occur leukopenia repeatedly, several different methods is failed to respond to any medical treatment, and makes chemotherapy can't carry out the traditional Chinese medical science of seeking medical advice, took the present invention 15 days, leukocyte rises to normally, after consolidate a course of treatment, finish 6 chemotherapy smoothly and do not recur.
4, Cai XX, leukopenia appears in postoperative rectal cancer chemotherapy repeatedly, the western medical treatment poor effect, the traditional Chinese medical science of seeking medical advice is taken 2 courses of treatment of the present invention and is healed, recurrence again.

Claims (2)

  1. One kind the treatment chemicotherapy after leukopenic Chinese medicine, it is characterized in that it is made up of the component of following raw materials in weight drug ratio: Radix Panacis Quinquefolii 10-12g, Rhizoma Atractylodis Macrocephalae (parched) 10-12g, Radix Astragali 30-35g, Fructus Lycii 12-14g, Fructus Psoraleae 8-10g, Pericarpium Citri Reticulatae 10-12g, Radix Paeoniae Alba 10-12g, Radix Angelicae Sinensis 10-13g, Rhizoma Polygonati 28-33g, Radix Glycyrrhizae Preparata 6-8g.
  2. One kind the treatment chemicotherapy after leukopenic Chinese medicine, it is preferably formed is Radix Panacis Quinquefolii 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Astragali 30g, Fructus Lycii 12g, Fructus Psoraleae 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Angelicae Sinensis 10g, Rhizoma Polygonati 30g, Radix Glycyrrhizae Preparata 6g.
CN201010502454A 2010-10-11 2010-10-11 Chinese medicament for treating luekopenia after concurrent chemoradiotherapy Expired - Fee Related CN101953994B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404490A (en) * 2022-03-31 2022-04-29 江西纤仁本草堂生物科技有限公司 Traditional Chinese medicine for treating leucopenia after tumor radiotherapy and chemotherapy and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1160560A (en) * 1996-03-21 1997-10-01 廖柏松 Chinese patent drug for curing leukopenia and its preparation process
CN1970036A (en) * 2005-11-24 2007-05-30 王精益 Chinese medicinal decoction for treating leucopenia caused by cancer radiochemical therapy and method for preparing same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1160560A (en) * 1996-03-21 1997-10-01 廖柏松 Chinese patent drug for curing leukopenia and its preparation process
CN1970036A (en) * 2005-11-24 2007-05-30 王精益 Chinese medicinal decoction for treating leucopenia caused by cancer radiochemical therapy and method for preparing same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
《光明中医》 20000531 吴继萍等 中医药防治放化疗毒副反应的临床研究 46-49 1-2 第15卷, 第90期 2 *
《解放军药学学报》 20011231 朱秀美等 国内中药防治化疗药物毒副作用的研究概况 321-323,封三 1-2 第17卷, 第6期 2 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404490A (en) * 2022-03-31 2022-04-29 江西纤仁本草堂生物科技有限公司 Traditional Chinese medicine for treating leucopenia after tumor radiotherapy and chemotherapy and preparation method thereof

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