CN101925603B - 囊性纤维化跨膜通道调节因子的调节剂 - Google Patents

囊性纤维化跨膜通道调节因子的调节剂 Download PDF

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CN101925603B
CN101925603B CN2008801255937A CN200880125593A CN101925603B CN 101925603 B CN101925603 B CN 101925603B CN 2008801255937 A CN2008801255937 A CN 2008801255937A CN 200880125593 A CN200880125593 A CN 200880125593A CN 101925603 B CN101925603 B CN 101925603B
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phenyl
methyl
compound
oxo
pyrimidine
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CN101925603A (zh
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H·宾奇
P·D·J·格鲁滕休斯
A·皮尔斯
L·T·D·范宁
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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CN2008801255937A 2007-12-13 2008-12-12 囊性纤维化跨膜通道调节因子的调节剂 Expired - Fee Related CN101925603B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1333607P 2007-12-13 2007-12-13
US61/013,336 2007-12-13
PCT/US2008/086562 WO2009076593A1 (en) 2007-12-13 2008-12-12 Modulators of cystic fibrosis transmembrane conductance regulator

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CN101925603A CN101925603A (zh) 2010-12-22
CN101925603B true CN101925603B (zh) 2013-12-04

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CN2008801255937A Expired - Fee Related CN101925603B (zh) 2007-12-13 2008-12-12 囊性纤维化跨膜通道调节因子的调节剂

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US (2) US8552006B2 (enExample)
EP (1) EP2231671B1 (enExample)
JP (1) JP5637859B2 (enExample)
CN (1) CN101925603B (enExample)
AU (1) AU2008335031B2 (enExample)
CA (1) CA2709301C (enExample)
ES (1) ES2422741T3 (enExample)
NZ (1) NZ586271A (enExample)
WO (1) WO2009076593A1 (enExample)

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